Data Science Lead Jobs in Chicago, IL
Data Science Lead jobs in Chicago are concentrated in the Loop, River North, and the Fulton Market tech corridor, with strong hiring across financial services, healthcare analytics, and enterprise software. Employers posting openings right now include NORC at the University of Chicago, University of Illinois, and Stripe. See the openings below and apply to the ones that match your experience.
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Who You Are
You are passionate about leveraging data, machine learning/AI and operational execution to improve patient outcomes. Your mandate will be to build a worldclass data science function that develops, deploys and maintains data marts and machine learning models that can also assess the impact of our clinical interventions. You're a leader who cares deeply about outcomes and impact. You are a collaborative leader who can help bridge the gap between clinical strategy, operational execution and technology. You have rich experience with health plan (claims, eligibility, pharmacy) and clinical (EMR, HIE) data. You can build data-marts in DBT and leverage those data marts to build new machine learning models.
Who We Are
Oasis Health Partners (Oasis) is an all-in-one partner for independent primary care practices. We focus on Medicare value-based care programs, including Medicare Advantage and MSSP, and surround practices with the practical support they need to deliver better care while building durable, independent businesses.
Our model helps physicians spend more time on proactive, high-value care for seniors while Oasis brings the data, tools and team to support them behind the scenes. We are building a fast-growing network of independent PCPs and IPAs, backed by leading healthcare investors and scaling into new markets as we expand our suite of provider solutions. We are committed to keeping independent medicine strong — and we are looking for people who want to build that future with us.
Together, we will boldly advance primary care for those that need it most. We are excited for you to join us on this journey. We invite you to be a part of Oasis, where you will discover we do the right thing, build things together and go all in - all while having fun!
Your Role
As a Director of Data Science, you will:
- Own our machine learning strategy and execution
- Collaborate within the tech team, clinical, and operations to implement best-in-class clinical interventions
- Set up analytics data models in DBT
- Identify additional sources of data we can use to identify / risk stratify patients for intervention, and understand the impact of our program
- Build out predictive models to identify high risk patients
- Utilize AI/LLMs to advance patient and provider engagement
- Analyze clinical data we receive from payors and providers
- Analyze clinical program performance
- Analyze workflow and operational data
- Develop the analytics layer to support executive and operational dashboards
Investment In Our Team
We invest in the personal and professional success of our team. We take care of our people and offer robust benefits including medical, dental, vision, 401k, and generous time off plans. We are committed to supporting your growth with a development program that starts with onboarding and continues throughout your career. As an inclusive, passionate, and diverse team, you will partner with professionals who understand the importance of high-value, high-impact patient care.
We invite you to be a part of Oasis, where you will discover we listen first, build things together, always do the right thing, have fun and most importantly, are all in!
About You
- Minimum 8 years of experience in healthcare analytics with hands-on expertise in real-world data
- Minimum 3 years of experience leading data science teams in healthcare
- Advanced SQL skills for complex data analysis and reporting
- Advanced Python skills for building and productionalizing machine learning models
- Experience in developing impactful BI reports and dashboards for end-users
- Quick learner with a demonstrated ability to adapt to new technologies
- Comfortable working in the ambiguity and rapid change of a startup environment
- Excellent communication skills for effective collaboration with technical and non-technical teams, including operational and clinical teams
- Ability to manage and prioritize multiple tasks and projects effectively
Preferred Experience
- Previous experience at a health plan or Managed Service Organization
- Familiarity with Medicare Advantage populations and their unique healthcare needs
- Background in value-based care organizations
- Experience with the Oasis data stack, including AWS, DBT, and Snowflake
The salary range listed reflects the full compensation range for this role level at Oasis and is designed to support growth over time. Actual offers may vary based on a candidate's skills, experience, and alignment with the scope of the role. Offers near the top of the range are uncommon and generally reflect exceptionally deep, directly relevant experience.
At this time, we are unable to sponsor employment visas. Candidates must be authorized to work in the United States without a current or future visa sponsorship. This role is open to applicants currently residing in the United States.
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status, or disability status.
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Who's Hiring



Top Industries Hiring
- Education
- Media & Entertainment
- Banking & Financial Services
Data Science Lead Jobs in Chicago: Frequently Asked Questions
How do I get a data science lead job in Chicago?
Focus your search on Chicago's three dominant hiring pockets: the Loop's trading firms and banks, the Fulton Market tech corridor, and the Medical District's health systems. Candidates with experience in financial modeling, clinical analytics, or large-scale ML platform work stand out locally. Networking through Chicago-area data science meetups and targeting mid-size fintechs and insurtech companies can give you an edge that purely national job searches miss.
Which companies hire data science leads in Chicago?
Chicago data science lead roles are posted by NORC at the University of Chicago, University of Illinois, and Stripe and others right now, based on current listings on Migrate Mate as of September 2026. Chicago's hiring mix leans heavily toward financial institutions, health systems, and B2B software companies, so expect a range of enterprise-scale employers alongside growth-stage startups.
Are there remote data science lead jobs in Chicago?
Yes, though it varies: data science lead roles that are primarily analytical and strategic tend to be more remote-friendly than those requiring hands-on lab or trading-floor presence. About 100% of data science lead openings tied to Chicago are remote or hybrid as of September 2026, with hybrid arrangements most common among Chicago's tech and fintech employers.
How can I get a data science lead job in Chicago with little or no experience?
The most realistic entry path in Chicago is moving into a senior individual contributor data scientist role at a mid-size Chicago fintech, insurer, or health system, then stepping into a lead position internally. Chicago employers like regional banks and healthcare networks frequently promote from within. Building a portfolio with projects involving financial or clinical data and contributing to Chicago's active open-source and Kaggle community also helps establish credibility before you apply for lead-level roles.
Which industries hire the most data science leads in Chicago?
Chicago data science lead roles concentrate in Education, Media & Entertainment, and Banking & Financial Services, based on current listings on Migrate Mate as of September 2026. Chicago's position as a national hub for commodities trading, insurance underwriting, and large health systems creates sustained demand for data science leadership that other Midwest cities don't match.
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