Data Science Lead Jobs in Chicago, IL

Data Science Lead jobs in Chicago are concentrated in the Loop, River North, and the Fulton Market tech corridor, with strong hiring across financial services, healthcare analytics, and enterprise software. Employers posting openings right now include Federal Reserve Bank of Chicago, UST, and AbbVie. See the openings below and apply to the ones that match your experience.

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Overview

Open roles37
Top employerFederal Reserve Bank of Chicago
Work type71% Hybrid
Top credentialBachelor's degree in statistics
Companies hiring19

Showing 5 of 37+ Data Science Lead jobs

VP of AI, Data and Data Science
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Added 4d ago
VP of AI, Data and Data Science
Sims Limited
Chicago, Illinois
Account Management
Customer Service
Customer Success
Bachelor's degree in engineering
5,001-10,000

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Manager - Data Science & AI
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Added 5d ago
Manager - Data Science & AI
Suntory Global Spirits
Chicago, Illinois
Business Analysis
Data Analytics
Data Science
$130k - $150k/yr
Doctoral degree in statistics

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Data Science Program Lead I - Oncology
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Added 1w ago
Data Science Program Lead I - Oncology
AbbVie
Chicago, Illinois
Clinical Trials
Healthcare Administration
Project Management
$85k - $162k/yr
Remote (US)
Bachelor's degree in management information systems
10,000+

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Director of Data Science
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Added 1w ago
Director of Data Science
AHOLD Delhaize
Chicago, Illinois
Business Strategy
Executive Leadership & C-Suite
Strategy & Corporate Development
$160k - $240k/yr
Hybrid
Master's degree
10,000+

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Senior Manager, Data Science
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Added 1w ago
Senior Manager, Data Science
Bain & Company
Chicago, Illinois
Data Analytics
Data Science
$165k - $198k/yr
Bachelor's degree in statistics
10,000+

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See All 37 Data Science Lead Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

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Data Science Lead Job Market in Chicago

Who's Hiring

Federal Reserve Bank of Chicago4 open roles
UST2 open roles
AbbVie2 open roles

Top Industries Hiring

  • Media & Entertainment
  • Banking & Financial Services

Data Science Lead Jobs in Chicago: Frequently Asked Questions

How do I get a data science lead job in Chicago?

Focus your search on Chicago's three dominant hiring pockets: the Loop's trading firms and banks, the Fulton Market tech corridor, and the Medical District's health systems. Candidates with experience in financial modeling, clinical analytics, or large-scale ML platform work stand out locally. Networking through Chicago-area data science meetups and targeting mid-size fintechs and insurtech companies can give you an edge that purely national job searches miss.

Which companies hire data science leads in Chicago?

Chicago data science lead roles are posted by Federal Reserve Bank of Chicago, UST, and AbbVie and others right now, based on current listings on Migrate Mate as of November 2026. Chicago's hiring mix leans heavily toward financial institutions, health systems, and B2B software companies, so expect a range of enterprise-scale employers alongside growth-stage startups.

Are there remote data science lead jobs in Chicago?

Yes, though it varies: data science lead roles that are primarily analytical and strategic tend to be more remote-friendly than those requiring hands-on lab or trading-floor presence. About 100% of data science lead openings tied to Chicago are remote or hybrid as of November 2026, with hybrid arrangements most common among Chicago's tech and fintech employers.

How can I get a data science lead job in Chicago with little or no experience?

The most realistic entry path in Chicago is moving into a senior individual contributor data scientist role at a mid-size Chicago fintech, insurer, or health system, then stepping into a lead position internally. Chicago employers like regional banks and healthcare networks frequently promote from within. Building a portfolio with projects involving financial or clinical data and contributing to Chicago's active open-source and Kaggle community also helps establish credibility before you apply for lead-level roles.

Which industries hire the most data science leads in Chicago?

Chicago data science lead roles concentrate in Media & Entertainment and Banking & Financial Services, based on current listings on Migrate Mate as of November 2026. Chicago's position as a national hub for commodities trading, insurance underwriting, and large health systems creates sustained demand for data science leadership that other Midwest cities don't match.

See All 37 Data Science Lead Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

Find Data Science Lead Jobs