Data Science Lead Jobs in Chicago, IL

Data Science Lead jobs in Chicago are concentrated in the Loop, River North, and the Fulton Market tech corridor, with strong hiring across financial services, healthcare analytics, and enterprise software. Employers posting openings right now include NORC at the University of Chicago, University of Illinois, and Stripe. See the openings below and apply to the ones that match your experience.

Find Data Science Lead Jobs

Overview

Open roles22
Top employerNORC at the University of Chicago
Work type93% Hybrid
Top credentialBachelor's degree
Companies hiring12

Showing 5 of 22+ Data Science Lead jobs

Oasis Health Partners
Director of Data Science
We won't show you this job again
Oasis Health Partners
Added 3d ago
Director of Data Science
Oasis Health Partners
Chicago, Illinois
Business Analysis
Data Analytics
Data Science
Remote (US)
Managed care organization experience

Have you applied for this role?

CCC Intelligent Solutions
R&D & Data Science Internship Fall 2026
We won't show you this job again
CCC Intelligent Solutions
Added 6d ago
R&D & Data Science Internship Fall 2026
CCC Intelligent Solutions
Chicago, Illinois
Healthcare Administration
Patient Services & Wellbeing
Physical Therapy
$20 - $43/hr
1,001-5,000

Have you applied for this role?

NORC at the University of Chicago
Senior Vice President – Statistics and Data Science Department - Chicago Loop Office
We won't show you this job again
NORC at the University of Chicago
Added 6d ago
Senior Vice President – Statistics and Data Science Department - Chicago Loop Office
NORC at the University of Chicago
Chicago, Illinois
Business Operations
Business Strategy
Consulting & Professional Services
$285k - $315k/yr
Hybrid
1,001-5,000

Have you applied for this role?

National Futures Association
Summer 2027 Centralized Data Science and Analytics Intern
We won't show you this job again
National Futures Association
Added 2w ago
Summer 2027 Centralized Data Science and Analytics Intern
National Futures Association
Chicago, Illinois
Accounting
Business Operations
Tax
501-1,000

Have you applied for this role?

Northern Trust Corp.
Technology Intern – Data Science and Analytics
We won't show you this job again
Northern Trust Corp.
Added 2w ago
Technology Intern – Data Science and Analytics
Northern Trust Corp.
Chicago, Illinois
Data Analytics
Data Science
Healthcare Administration
10,000+

Have you applied for this role?

See All 22 Data Science Lead Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

Find Data Science Lead Jobs

Data Science Lead Job Market in Chicago

Who's Hiring

NORC at the University of Chicago
NORC at the University of Chicago4 open roles
University of Illinois
University of Illinois3 open roles
Stripe
Stripe1 open role

Top Industries Hiring

  • Education
  • Media & Entertainment
  • Banking & Financial Services

Data Science Lead Jobs in Chicago: Frequently Asked Questions

How do I get a data science lead job in Chicago?

Focus your search on Chicago's three dominant hiring pockets: the Loop's trading firms and banks, the Fulton Market tech corridor, and the Medical District's health systems. Candidates with experience in financial modeling, clinical analytics, or large-scale ML platform work stand out locally. Networking through Chicago-area data science meetups and targeting mid-size fintechs and insurtech companies can give you an edge that purely national job searches miss.

Which companies hire data science leads in Chicago?

Chicago data science lead roles are posted by NORC at the University of Chicago, University of Illinois, and Stripe and others right now, based on current listings on Migrate Mate as of September 2026. Chicago's hiring mix leans heavily toward financial institutions, health systems, and B2B software companies, so expect a range of enterprise-scale employers alongside growth-stage startups.

Are there remote data science lead jobs in Chicago?

Yes, though it varies: data science lead roles that are primarily analytical and strategic tend to be more remote-friendly than those requiring hands-on lab or trading-floor presence. About 100% of data science lead openings tied to Chicago are remote or hybrid as of September 2026, with hybrid arrangements most common among Chicago's tech and fintech employers.

How can I get a data science lead job in Chicago with little or no experience?

The most realistic entry path in Chicago is moving into a senior individual contributor data scientist role at a mid-size Chicago fintech, insurer, or health system, then stepping into a lead position internally. Chicago employers like regional banks and healthcare networks frequently promote from within. Building a portfolio with projects involving financial or clinical data and contributing to Chicago's active open-source and Kaggle community also helps establish credibility before you apply for lead-level roles.

Which industries hire the most data science leads in Chicago?

Chicago data science lead roles concentrate in Education, Media & Entertainment, and Banking & Financial Services, based on current listings on Migrate Mate as of September 2026. Chicago's position as a national hub for commodities trading, insurance underwriting, and large health systems creates sustained demand for data science leadership that other Midwest cities don't match.

See All 22 Data Science Lead Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

Find Data Science Lead Jobs