E-3 Visa Clinical Research Nurse Jobs
Clinical Research Nurse jobs in the U.S. qualify for E-3 visa sponsorship when the role requires a bachelor's degree in nursing and a registered nurse license. The E-3 has no lottery and no annual cap, making it a reliable path for Australian nurses moving into clinical trials work.
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Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.
ROLE AND RESPONSIBILITIES
Work collaboratively with physicians, Clinical Research Associates (CRA) and pharmacists to coordinate care for an assigned population of patients who are enrolled in clinical research trials. You will assist in the assessment, management and coordination of care across the continuum of care (outpatient, inpatient and home) including triage of phone calls and proactive patient communication. You will educate patients and families on the clinical trial treatments and required testing.
As a successful candidate, you will:
- Collaborate with the investigator to ascertain study patient eligibility for clinical trial, including documentation of criteria specified in the clinical trial.
- Assess, identify and prioritize clinical information to physician, NP, PA and other clinicians for patients who are being evaluated or who are enrolled in to IRB clinical trials.
- Assess and document signs and symptoms of illness, reactions to treatment, changes in physical or psychological condition and general appearance in accordance with the IRB protocol assuring that the documentation is complete and accurate in order to avoid protocol deviations.
- Manage patient/family phone calls – collaborating with MD, NP and/or PA as needed to obtain orders for the management of the patient.
- Ensure the consent process is performed in compliance with institutional, FDA, IRB, clinical trial sponsor and other applicable regulations.
- Support Peds, head/neck and other specialties.
BASIC QUALIFICATIONS
Your qualifications should include:
- BSN
- 2 or more years of experience in oncology, clinical research, research, ICU, other intensive care setting, pediatrics, case management or nurse navigation.
- Human subjects protection training (can be completed after hire).
Required Certification/Licensure:
- Current California RN License
- American Heart Association BLS Certification
COMPENSATION
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, please CLICK HERE.

Join the transformative team at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. City of Hope’s growing national system includes its Los Angeles campus, a network of clinical care locations across Southern California, a new cancer center in Orange County, California, and treatment facilities in Atlanta, Chicago and Phoenix. Our dedicated and compassionate employees are driven by a common mission: To deliver the cures of tomorrow to the people who need them today.
ROLE AND RESPONSIBILITIES
Work collaboratively with physicians, Clinical Research Associates (CRA) and pharmacists to coordinate care for an assigned population of patients who are enrolled in clinical research trials. You will assist in the assessment, management and coordination of care across the continuum of care (outpatient, inpatient and home) including triage of phone calls and proactive patient communication. You will educate patients and families on the clinical trial treatments and required testing.
As a successful candidate, you will:
- Collaborate with the investigator to ascertain study patient eligibility for clinical trial, including documentation of criteria specified in the clinical trial.
- Assess, identify and prioritize clinical information to physician, NP, PA and other clinicians for patients who are being evaluated or who are enrolled in to IRB clinical trials.
- Assess and document signs and symptoms of illness, reactions to treatment, changes in physical or psychological condition and general appearance in accordance with the IRB protocol assuring that the documentation is complete and accurate in order to avoid protocol deviations.
- Manage patient/family phone calls – collaborating with MD, NP and/or PA as needed to obtain orders for the management of the patient.
- Ensure the consent process is performed in compliance with institutional, FDA, IRB, clinical trial sponsor and other applicable regulations.
- Support Peds, head/neck and other specialties.
BASIC QUALIFICATIONS
Your qualifications should include:
- BSN
- 2 or more years of experience in oncology, clinical research, research, ICU, other intensive care setting, pediatrics, case management or nurse navigation.
- Human subjects protection training (can be completed after hire).
Required Certification/Licensure:
- Current California RN License
- American Heart Association BLS Certification
COMPENSATION
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, please CLICK HERE.
See all 71+ Clinical Research Nurse jobs
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Get Access To All JobsTips for Finding E-3 Visa Sponsorship as a Clinical Research Nurse
Verify your credentials meet U.S. requirements
Your Australian nursing registration doesn't automatically transfer. You'll need to pass the NCLEX-RN and obtain state licensure before most U.S. employers can file your E-3 LCA. Start credential verification through your target state's nursing board early.
Target academic medical centers and CROs
Academic medical centers, hospital research departments, and contract research organizations file E-3 LCAs regularly for clinical research roles. These employers already understand specialty occupation requirements, so sponsorship conversations are less likely to stall over unfamiliarity with the visa.
Frame your application around specialty occupation
Clinical Research Nurse roles must qualify as a specialty occupation for the E-3. Emphasize your degree in nursing and protocol-specific responsibilities in your resume and cover letter, not general bedside care tasks, so the DOL and consular officer see a clear degree-to-role connection.
Ask about LCA filing before accepting an offer
Your employer files the LCA with the DOL before you can apply for your E-3 at the consulate. Confirm during negotiations that HR is prepared to file promptly, since delays in LCA certification can push your start date back by weeks.
Use Migrate Mate's E-3 filing service for the process
Once you have a job offer, use Migrate Mate's E-3 filing service to handle your LCA and visa paperwork end-to-end, from DOL submission through consulate appointment preparation, so nothing falls through the gaps during the filing window.
Search for roles using E-3 sponsorship filters
Generic job searches return results with no indication of sponsorship willingness. Migrate Mate filters Clinical Research Nurse roles by verified E-3 sponsorship history, so you apply to employers who have already navigated the process for Australian candidates.
Clinical Research Nurse jobs are hiring across the US. Find yours.
Find Clinical Research Nurse JobsClinical Research Nurse E-3 Visa: Frequently Asked Questions
How do I find Clinical Research Nurse jobs with E-3 visa sponsorship?
Migrate Mate is the most direct way to search. It filters Clinical Research Nurse listings by employers with verified E-3 sponsorship history, so you're not spending time on roles where the hiring manager has never heard of the visa. Standard job boards don't surface sponsorship intent, which means most applications go nowhere for visa-requiring candidates.
How much does it cost to get an E-3 visa?
Migrate Mate's E-3 filing service covers the entire process for $499, including the Labor Condition Application, visa document preparation, and consulate appointment guidance. Traditional immigration lawyers charge $2,000–$5,000+ for the same work. The E-3 has less paperwork than most work visas, so paying thousands for legal help is usually unnecessary.
Does the Clinical Research Nurse role qualify as a specialty occupation for the E-3?
Yes, provided the position requires a bachelor's degree in nursing as a minimum entry requirement. Clinical Research Nurse roles that involve protocol management, patient safety monitoring, and regulatory compliance under a BSN requirement consistently meet the DOL's specialty occupation standard. Roles that accept any nursing credential regardless of degree level are more likely to face scrutiny during LCA review.
How does the E-3 compare to the H-1B for Clinical Research Nurses?
The E-3 is available only to Australian citizens, but it has two major practical advantages over the H-1B for this role. There's no annual cap and no lottery, so your employer can file at any point in the year with a near-certain path to approval. H-1B petitions for the same role are subject to a randomized annual lottery with no guarantee of selection, regardless of qualifications.
Can I transfer my E-3 if I move to a different clinical research employer in the U.S.?
Yes, but each new employer must file a fresh LCA with the DOL and you'll need to either apply for a new E-3 at an Australian consulate or, in some cases, complete a change of status through USCIS. You can't simply carry your existing E-3 to a new employer the way some other visa types allow portability. Plan the transition timeline with your new employer before resigning from your current role.
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