Engineering Jobs in St. Louis, MO
Engineering jobs in St. Louis are concentrated in aerospace, defense, manufacturing, and biomedical research, with major activity in the Cortex Innovation Community, Chesterfield Valley, and downtown along the riverfront. Employers hiring right now include Introba, Nidec Motor Corporation, and Thermo Fisher Scientific. Find a role that fits below and apply directly.
Find Engineering JobsOverview
Showing 5 of 55+ Engineering jobs
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.
How will you make an impact?
The Thermo Fisher Scientific St. Louis site is a multi-product and multi-client biopharmaceutical site with manufacturing facilities for pharmaceutical products for both (pre)clinical trials and commercial applications. The Staff Engineer role is part of the Engineering team and reports to the Manager of Manufacturing Engineering. This role focuses on managing and supporting capital projects to enhance our manufacturing capabilities and ensure compliance with GMP standards.
What you will do
- Manage contractors and capital projects up to $5MM.
- Develop and track scope, schedule, and budget for capital projects.
- Initiate, manage and close quality records related to capital projects.
- Drive closure of intermediate tasks on quality records to ensure departmental compliance and on-time completion.
- Author and Review GMP documents as required to support capital project objectives.
- Lead start-up and commissioning activities on capital projects.
- Ensure all capital projects comply with regulatory requirements, industry standards, and company policies.
- Collaborate with cross-functional teams including MSAT, PD, Quality, Operations, and Maintenance to ensure project alignment with business objectives.
- Conduct feasibility studies, prepare detailed project plans, and manage project timelines and budgets.
- Perform risk assessments and develop mitigation strategies to ensure successful project execution.
- Engage with business leadership as required for projects to attain business approval and ensure alignment of project deliverables with business objectives.
- Engage with customers and regulators as required for managed projects and areas of expertise.
- Drive adherence to site safety standards in delivering projects including applicable assessments of new facilities and equipment.
Education:
- Bachelor’s Degree or higher education in Engineering (Chemical, Mechanical, Electrical, Bio) and 5+ years experience, 8+ preferred.
- Associates Degree and 8+ years of related professional experience.
Experience
- 5+ years of pharmaceutical industry experience or experience in a similar industry
- Past experience managing contractors and projects up to $5MM
- Experience authoring documents in a GMP setting.
- Experience working in a cleanroom.
- Prior experience working on commissioning and validation in a pharmaceutical setting.
Knowledge, Skills, Abilities
- Knowledge of building codes and regulations.
- Understanding of regulatory requirements for pharmaceutical facilities.
- Excellent written and verbal communication
- Strong attention to detail
- Proficient with Microsoft Excel, Word, Outlook, Project and PowerPoint
- Proficient with AutoCad and Bluebeam
Benefits
We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!
Other
Relocation assistance is not provided.
Must be legally authorized to work in the United States now and in the future, without sponsorship.
Must be able to pass a comprehensive background check, which includes a drug screening.
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.
How will you make an impact?
The Thermo Fisher Scientific St. Louis site is a multi-product and multi-client biopharmaceutical site with manufacturing facilities for pharmaceutical products for both (pre)clinical trials and commercial applications. The Staff Engineer role is part of the Engineering team and reports to the Manager of Manufacturing Engineering. This role focuses on managing and supporting capital projects to enhance our manufacturing capabilities and ensure compliance with GMP standards.
What you will do
- Manage contractors and capital projects up to $5MM.
- Develop and track scope, schedule, and budget for capital projects.
- Initiate, manage and close quality records related to capital projects.
- Drive closure of intermediate tasks on quality records to ensure departmental compliance and on-time completion.
- Author and Review GMP documents as required to support capital project objectives.
- Lead start-up and commissioning activities on capital projects.
- Ensure all capital projects comply with regulatory requirements, industry standards, and company policies.
- Collaborate with cross-functional teams including MSAT, PD, Quality, Operations, and Maintenance to ensure project alignment with business objectives.
- Conduct feasibility studies, prepare detailed project plans, and manage project timelines and budgets.
- Perform risk assessments and develop mitigation strategies to ensure successful project execution.
- Engage with business leadership as required for projects to attain business approval and ensure alignment of project deliverables with business objectives.
- Engage with customers and regulators as required for managed projects and areas of expertise.
- Drive adherence to site safety standards in delivering projects including applicable assessments of new facilities and equipment.
Education:
- Bachelor’s Degree or higher education in Engineering (Chemical, Mechanical, Electrical, Bio) and 5+ years experience, 8+ preferred.
- Associates Degree and 8+ years of related professional experience.
Experience
- 5+ years of pharmaceutical industry experience or experience in a similar industry
- Past experience managing contractors and projects up to $5MM
- Experience authoring documents in a GMP setting.
- Experience working in a cleanroom.
- Prior experience working on commissioning and validation in a pharmaceutical setting.
Knowledge, Skills, Abilities
- Knowledge of building codes and regulations.
- Understanding of regulatory requirements for pharmaceutical facilities.
- Excellent written and verbal communication
- Strong attention to detail
- Proficient with Microsoft Excel, Word, Outlook, Project and PowerPoint
- Proficient with AutoCad and Bluebeam
Benefits
We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!
Other
Relocation assistance is not provided.
Must be legally authorized to work in the United States now and in the future, without sponsorship.
Must be able to pass a comprehensive background check, which includes a drug screening.
See All 55 Engineering Jobs in St. Louis
Find roles in St. Louis that match your experience and apply in just a few clicks.
Find Engineering JobsEngineering Job Market in St. Louis
Who's Hiring
Engineering Jobs in St. Louis: Frequently Asked Questions
How do I get a engineering job in St. Louis?
Target the sectors that drive St. Louis engineering demand most directly: aerospace and defense contractors in the western suburbs, chemical and agricultural engineering firms along the Missouri River corridor, and biomedical device companies anchored in the Cortex Innovation Community. Civil and infrastructure roles are active downtown and in the Metro East. Candidates with hands-on project experience, relevant certifications, and familiarity with advanced manufacturing processes stand out in this market.
Which companies hire engineerings in St. Louis?
Companies currently hiring engineerings in St. Louis include Introba, Nidec Motor Corporation, and Thermo Fisher Scientific, per current listings on Migrate Mate as of November 2026. St. Louis draws a broad mix of legacy industrial employers, defense contractors, and fast-growing life sciences and clean energy firms, giving engineers a wide range of workplace environments and project types to choose from.
Are there remote engineering jobs in St. Louis?
Yes, though availability depends heavily on the discipline, since hands-on and field roles are almost always on-site while software, systems, and data-focused engineering roles often allow remote or hybrid arrangements. About 80% of engineering openings tied to St. Louis are remote or hybrid as of November 2026, with the highest concentration in the technology and biomedical sectors anchored in the Cortex district.
How can I get a engineering job in St. Louis with little or no experience?
The most realistic entry path in St. Louis is through co-op and internship programs at the city's manufacturing and aerospace employers, which frequently convert to full-time roles. Entry-level openings for process, quality, and test engineers are common at mid-size industrial firms in Chesterfield and Maryland Heights. Familiarity with CAD software, lean manufacturing principles, or laboratory instrumentation gives candidates a concrete edge over general applicants in this market.
Related Jobs in Missouri
See All 55 Engineering Jobs in St. Louis
Find roles in St. Louis that match your experience and apply in just a few clicks.
Find Engineering Jobs