Engineering Jobs in Knoxville, TN
Engineering jobs in Knoxville are in strong demand, concentrated in the Oak Ridge corridor, the University of Tennessee research district, and the downtown Innovation Valley along the Tennessee River waterfront, with heavy hiring across nuclear, advanced manufacturing, and civil infrastructure sectors. Employers posting right now include University of Tennessee Health Science Center, Siemens Healthineers, and HII. See the openings below and apply to the ones that match your experience.
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The Laboratory Manager for Radiological Sciences supports the day-to-day operations of research laboratories supporting radiopharmaceutical sciences, reporting to the Nuclear Engineering Laboratory and Safety Manager. This position supports safe research operation and compliance with environmental, chemical, biological, and radiation safety regulations; coordinates laboratory maintenance and equipment upkeep. The position will support the management and documentation of laboratory supplies and help ensure research is performed following the documented safety protocols. The Laboratory Manager will work closely with faculty, staff, and students to maintain a safe, efficient, and productive research environment.
Coordinate with faculty and the department laboratory manager to ensure safe, organized and efficient research operations occur in compliance with institutional, state, and federal regulations related to radiation safety, environmental health and safety (EHS), biosafety, and animal research.
Make sure machines are running safely based on the guidance from lab manager and assist with ensuring that safety protocols are in place and communicated with everyone in the lab.
Assist in the training of laboratory personnel in radiation safety, biosafety, chemical safety, and best laboratory practices related to radiopharmaceutical sciences.
Draft and update laboratory protocols, standard operating procedures (SOPs), and regulatory documentation for management approval.
Serve as the point of contact with the University's Radiation Safety Office, EHS, Institutional Biosafety Committee (IBC), and Institutional Animal Care and Use Committee (IACUC). Will provide knowledge to these partners as appropriate and filter the remaining concerns or questions with the manager.
Maintain accurate laboratory records to be up to date and comply with regulatory compliance for random inspections that occur.
Work with department procurement specialist and department laboratory manager regarding the ordering, receipt, inventory, and waste management of radioactive materials. This role will assist the procurement specialist lab needs to allow that specialist to ensure they're meeting policies and guidelines on ordering and coordinating bids for equipment and work orders. This role will ensure that those orders and bids are within budget guidelines provided to the research lab manager.
Operate and maintain research instrumentation, including the IQID camera, PET/CT scanner, Gamma-Eye imaging system, IVIS imaging system, tissue sectioning equipment, and other laboratory instruments used in radiopharmaceutical sciences.
Train laboratory personnel on the proper operation and maintenance of laboratory equipment as the SME.
Coordinate routine maintenance, troubleshooting, calibration, and service of laboratory instrumentation.
Serve as a point of contact for equipment vendors and service engineers to ensure all laboratory equipment remains operational and properly maintained.
Assist faculty Principal Investigators (PIs) in preparing the laboratory safety protocol documents and detailing experimental methods that can support the technical sections of manuscripts, grant proposals, and research reports. Provide support with experiment planning and logistical coordination, including estimating and budgeting user facility charges for the experimental costs, supplies, equipment, and radiopharmaceutical-related research expenses.
Required Qualifications
- Education: Bachelor’s in biology, chemistry, biomedical sciences, laboratory science, or a related field
- Experience:
- Minimum of two years of relevant laboratory experience.
- Experience should demonstrate proficiency in standard laboratory practices, adherence to chemical and biological safety requirements, accurate documentation, and the ability to independently perform routine laboratory procedures.
Knowledge, Skills, Abilities:
- Knowledge of lab operations & safety procedures
- Knowledge of laboratory scientific principles/techniques
- Ability to troubleshoot and maintain lab equipment
- Knowledge and ability to comply with federal, state, local, and university regulations and requirements
- Strong attention to detail
Preferred Qualifications
- Education: Master’s in biology, chemistry, biomedical sciences, laboratory science, or a related field
Knowledge, Skills, Abilities: Knowledge, skills and abilities in working with cultured cells, mouse models of disease, and highly effective communication skills, both oral and written, are preferred.
Work Location
Location: Knoxville, TN
Onsite
Compensation and Benefits
- UT market range: MR08
Application Instructions
To express interest, please submit an application with the noted below attachments.
Resume
Cover Letter
List of 3 Professional References
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Who's Hiring
- University of Tennessee Health Science Center18

- Siemens Healthineers14

- HII5

- CDM Smith5

- ATC Drivetrain5

Top Industries Hiring
- Consulting & Professional Services
Engineering Jobs in Knoxville: Frequently Asked Questions
How do I get a engineering job in Knoxville?
Knoxville's strongest engineering demand comes from the nuclear and energy sector anchored near Oak Ridge, the advanced manufacturing plants along the I-75 and I-40 corridors, and civil and infrastructure firms tied to TVA projects and regional transportation work. Candidates with experience in nuclear systems, structural analysis, or process engineering gain an edge here. Connecting with the local Society of Civil Engineers chapter and attending UT Knoxville career events also puts you in front of the employers who hire most actively in this market.
Which companies hire engineerings in Knoxville?
Knoxville engineering roles are posted by University of Tennessee Health Science Center, Siemens Healthineers, and HII and others right now, based on current listings on Migrate Mate as of September 2026. The local market includes a distinctive mix of federal contractors supporting Oak Ridge National Laboratory, Tennessee Valley Authority vendors, and regional civil and mechanical engineering firms serving the construction and utilities sectors across East Tennessee.
Are there remote engineering jobs in Knoxville?
Yes, though remote availability in engineering depends heavily on the specialty, since hands-on roles in manufacturing, nuclear, or civil construction are almost always on-site, while systems engineering, data analysis, and software-adjacent engineering positions have more flexibility. About 74% of engineering openings tied to Knoxville are remote or hybrid as of September 2026, and the roles most likely to offer that flexibility are in systems integration, project controls, and technical consulting tied to Oak Ridge or TVA vendor work.
How can I get a engineering job in Knoxville with little or no experience?
The most realistic entry path in Knoxville is through co-op or internship programs with federal contractors and TVA suppliers near Oak Ridge, where structured training pipelines are common for candidates still completing engineering degrees. Entry-level civil and environmental roles at regional consulting firms serving municipal infrastructure projects are another strong starting point. A degree from UT Knoxville's engineering programs carries real name recognition with local employers, and candidates who have completed senior capstone projects with Knoxville-area companies often convert to full-time offers.
Which industries hire the most engineerings in Knoxville?
Most engineering openings in Knoxville sit in Consulting & Professional Services, per current listings on Migrate Mate as of September 2026. Knoxville's proximity to Oak Ridge National Laboratory and the Tennessee Valley Authority makes energy and government contracting the dominant drivers of local engineering hiring, while regional population growth sustains steady demand from civil and environmental firms working on transportation, utilities, and commercial development projects.
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