Full-stack Software Engineer Jobs in San Francisco, CA
Full-stack Software Engineer jobs in San Francisco concentrate in SoMa, the Financial District, and Mission Bay, with strong demand from employers in fintech, enterprise SaaS, AI infrastructure, and consumer technology. Employers actively hiring include OpenAI, Rippling, and Anthropic. Scan the live roles below and apply to whichever ones fit.
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Senior Software Engineer (Full-Stack)
Employment Type: Full-time
Work Type: Hybrid
Location: San Francisco
Company: Roger Healthcare
About This Role
We are looking for a Senior Software Engineer with 5+ years of experience to join our small, lean team of ten engineers. We are seeking a candidate with a strong backend focus, startup experience (Pre-seed to Series B), and a passion for healthcare. This individual will be a core team member, taking on significant ownership to help scale our core services and build new Generative AI and LLM-driven workflows.
What Will You Be Doing?
- Build and ship complex backend services and infrastructure that interface with LLMs and Generative AI models.
- Take ownership of zero-to-one projects, from prototyping MVPs to hardening them into scalable, secure, and reliable production systems.
- Help scale our existing, widely adopted products as we launch to more organizations.
- Improve backend architecture, observability, and code quality standards.
- Collaborate within a flat engineering structure, working directly with other engineers and the CTO.
Pay: $144,301.88 - $173,782.91 per year
Work Location: Hybrid remote in San Francisco, CA 94114
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Find JobsFull-stack Software Engineer Job Market in San Francisco
Who's Hiring
- OpenAI47

- Rippling33

- Anthropic8

- Atlassian8

- Salesforce8

Top Industries Hiring
- Technology & Software55
- Science & Research22
- Agriculture & Farming3
- Banking & Financial Services3
- Healthcare & Medical Services3
Full-stack Software Engineer Jobs in San Francisco: Frequently Asked Questions
How do I get a full-stack software engineer job in San Francisco?
Target fintech firms in the Financial District, AI and SaaS companies in SoMa, and biotech-adjacent tech teams in Mission Bay, since those sectors post the most full-stack openings in San Francisco. Candidates who can demonstrate experience with modern cloud infrastructure, API design, and React or Vue alongside a backend framework have a clear edge in this market. Contributing to open-source projects with Bay Area community visibility also helps.
Which companies hire full-stack software engineers in San Francisco?
San Francisco full-stack software engineer roles are posted by OpenAI, Rippling, and Anthropic and others right now, based on current listings on Migrate Mate as of September 2026. San Francisco's employer base is a mix of late-stage startups, established enterprise technology companies, and financial services firms that maintain significant engineering footprints in the city.
Are there remote full-stack software engineer jobs in San Francisco?
Yes, full-stack software engineering is well-suited to remote and hybrid arrangements since the core work happens in code editors, cloud environments, and collaborative tools rather than on-site. About 61% of full-stack software engineer openings tied to San Francisco are remote or hybrid as of September 2026, reflecting the sector's flexibility. Frontend-heavy and platform-focused roles tend to offer the most location flexibility among San Francisco postings.
How can I get a full-stack software engineer job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is through contract-to-hire roles at mid-size SaaS companies in SoMa, where teams are small enough to bring on junior engineers who show strong fundamentals. Early-career candidates can also target associate engineer and software engineering apprenticeship programs at San Francisco-based fintech and infrastructure companies. Building a portfolio that includes a deployed full-stack project with a real database and public API makes a concrete difference in this competitive market.
Which industries hire the most full-stack software engineers in San Francisco?
Most full-stack software engineer openings in San Francisco sit in Technology & Software, Science & Research, and Agriculture & Farming, per current listings on Migrate Mate as of September 2026. San Francisco's concentration of venture-backed technology companies, established fintech platforms, and AI-focused startups creates sustained demand for engineers who can own both the frontend and backend of a product.
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