Senior Clinical Research Scientist Green Card Jobs
Senior Clinical Research Scientist roles at pharmaceutical companies, CROs, and academic medical centers regularly qualify for EB-2 and EB-3 green card sponsorship through PERM labor certification. Employers file on your behalf, certifying that no equally qualified U.S. worker is available. Advanced degrees in life sciences and documented clinical trial experience strengthen both your PERM audit defense and your I-140 petition.
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Get Access To All JobsINTRODUCTION
Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 115,000 colleagues serve people in more than 160 countries.
Working at Abbott
At Abbott, you can do work that matters, grow, and learn, care for yourself and family, be your true self and live a full life. You’ll also have access to:
- Career development with an international company where you can grow the career you dream of
- Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year.
- An excellent retirement savings plan with high employer contribution
- Tuition reimbursement, the Freedom 2 Save student debt program and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree
- A company recognized as a great place to work in dozens of countries around the world and named one of the most admired companies in the world by Fortune
- A company that is recognized as one of the best big companies to work for as well as a best place to work for diversity, working mothers, female executives, and scientists
For years, Abbott’s medical device businesses have offered technologies that are faster, more effective, and less invasive. Whether it’s glucose monitoring system, innovative therapies for treating heart disease, or products that help people with chronic pain or movement disorders, our medical device technologies are designed to help people live their lives better and healthier. Every day, our technologies help more than 10,000 people have healthier hearts, improve quality of life for thousands of people living with chronic pain and movement disorders, and liberate more than 500,000 people with diabetes from routine fingersticks.
THE OPPORTUNITY
Our location in Sylmar, CA currently has an on-site opportunity for a Senior Clinical Research Scientist. This new team member will work in Abbott’s Global Data Science & Analytics team within the Medical Device Division. The Senior Clinical Research Scientist will provide scientific and technical leadership for real-world evidence (RWE) studies supporting post-market regulatory requirements, reimbursement, clinical evidence generations, and pre-market submissions across Abbott’s Electrophysiology portfolio. This individual will lead the design, execution, and dissemination of observational studies using large-scale real-world data sources, including electronic health records (EHR), insurance claims, hospital administrative and billing databases, and device-generated data.
What You’ll Work On
Real-World Evidence Study Leadership
- Lead the design and execution of real-world evidence, health economics, and digital health studies related to Abbott medical devices, using real-world data sources such as electronic health records, insurance claims, and hospital administrative/billing databases.
- Develop and own RWE study protocols and statistical analysis plans (SAPs) aligned with regulatory, clinical, and reimbursement objectives.
- Build and help execute long-term RWE generation strategies across the electrophysiology portfolio, in collaboration with clinical, regulatory, medical affairs, and market access stakeholders.
Data Analysis & Programming
- Perform hands-on programming to execute RWE studies using SQL, R, SAS, Python, or similar languages.
- Manage data preparation, cohort construction, variable derivation, and analysis across diverse data types, including EHR data, insurance claims, hospital billing data, device-generated data, and clinical trial data.
- Partner closely with data analysts and data engineers to validate programming logic, analytical datasets, and study results, ensuring accuracy, reproducibility, and regulatory readiness.
Scientific Communication & Disclosure
- Lead development of study reports, regulatory deliverables, conference abstracts, podium and poster presentations, and peer-reviewed scientific manuscripts.
- Translate complex analytical results into clear, clinically meaningful scientific narratives for internal leadership, regulators, clinicians, and external stakeholders.
Clinical & Therapeutic Area Expertise
- Maintain strong and up-to-date knowledge of the clinical landscape in cardiac electrophysiology, including atrial fibrillation, atrial flutter, ventricular arrhythmias, ablation technologies, and evolving standards of care.
- Monitor emerging evidence, clinical guidelines, competitive technologies, and unmet clinical needs to inform RWE study design, endpoint selection, and evidence generation strategy.
- Apply clinical context to interpret real-world data results, assess relevance to intended use populations, and support regulatory and clinical decision-making.
Cross-Functional Collaboration
- Collaborate effectively with peers across biostatistics, clinical affairs, regulatory affairs, medical affairs, health economics, and R&D teams.
- Represent RWE and observational research perspectives in cross-functional project teams and strategy discussions.
- Engage with external collaborators, including academic researchers, data vendors, and clinical experts, as appropriate.
Required Qualifications
- Associates Degree
- 4 years related experience
Preferred Qualifications
- Master's Degree with 4+ years of related experience OR Bachelor's Degree with 6-8 years of related experience OR an equivalent combination of education and work experience.
- PhD, DrPH, PharmD, MS, or equivalent advanced degree in biostatistics, epidemiology, clinical research, public health, outcomes research, biomedical engineering, or a related field. 2-5+ years’ Experience leading real-world evidence, observational research, or outcomes research studies in the medical device, pharmaceutical, or life sciences industry, with increasing levels of scientific responsibility.
- Experience designing and executing regulatory-grade clinical studies or RWE studies.
- Strong expertise working with large real-world datasets, including electronic health records, administrative claims data, hospital billing/chargemaster data, registries, and/or device-generated data.
- Advanced hands-on experience in statistical programming and data analysis using one or more of the following: SQL, R, SAS, Python (or equivalent), with the ability to independently execute complex cohort-based analyses.
- Deep understanding of epidemiologic study design and analytical methods for observational research, including cohort studies, comparative effectiveness research, signal detection, sensitivity analyses, and bias mitigation strategies.
- Proven ability to develop RWE protocols and statistical analysis plans suitable for regulatory review, including clear articulation of study objectives, endpoints, data sources, and analytical approaches.
- Familiarity with regulatory and methodological guidance relevant to real-world evidence, including FDA expectations for data relevance, reliability, and transparency.
- Prior experience leading the development of study reports, regulatory submissions, peer-reviewed manuscripts, conference abstracts, and scientific presentations.
- Background or strong working knowledge of the cardiac electrophysiology therapeutic area, including atrial fibrillation, atrial flutter, ventricular arrhythmias, catheter ablation technologies, and evolving standards of care, with the ability to interpret results in a clinically meaningful context.
- Demonstrated ability to stay current with the clinical and competitive landscape in electrophysiology, including emerging technologies, clinical guidelines, and real-world evidence trends.
- Experience collaborating effectively with cross-functional teams (e.g., clinical affairs, regulatory affairs, medical affairs, health economics, data science, biostatistics) and influencing without formal authority.
- Demonstrated ability to manage multiple complex projects simultaneously, prioritize effectively, and deliver high-quality scientific work under tight timelines, with strong attention to detail and commitment to analytical rigor.
- Strong scientific communication skills, with the ability to translate complex analyses into clear, actionable insights for diverse audiences, including clinicians, regulators, and internal leadership.
- Experience working with external collaborators such as academic investigators, data vendors, or health system partners is preferred.
Apply Now
Learn more about our health and wellness benefits, which provide the security to help you and your family live full lives: www.abbottbenefits.com
Follow your career aspirations to Abbott for diverse opportunities with a company that can help you build your future and live your best life.
Abbott is an Equal Opportunity Employer, committed to employee diversity.
The base pay for this position is $90,000.00 – $180,000.00. In specific locations, the pay range may vary from the range posted.
INTRODUCTION
Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 115,000 colleagues serve people in more than 160 countries.
Working at Abbott
At Abbott, you can do work that matters, grow, and learn, care for yourself and family, be your true self and live a full life. You’ll also have access to:
- Career development with an international company where you can grow the career you dream of
- Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year.
- An excellent retirement savings plan with high employer contribution
- Tuition reimbursement, the Freedom 2 Save student debt program and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree
- A company recognized as a great place to work in dozens of countries around the world and named one of the most admired companies in the world by Fortune
- A company that is recognized as one of the best big companies to work for as well as a best place to work for diversity, working mothers, female executives, and scientists
For years, Abbott’s medical device businesses have offered technologies that are faster, more effective, and less invasive. Whether it’s glucose monitoring system, innovative therapies for treating heart disease, or products that help people with chronic pain or movement disorders, our medical device technologies are designed to help people live their lives better and healthier. Every day, our technologies help more than 10,000 people have healthier hearts, improve quality of life for thousands of people living with chronic pain and movement disorders, and liberate more than 500,000 people with diabetes from routine fingersticks.
THE OPPORTUNITY
Our location in Sylmar, CA currently has an on-site opportunity for a Senior Clinical Research Scientist. This new team member will work in Abbott’s Global Data Science & Analytics team within the Medical Device Division. The Senior Clinical Research Scientist will provide scientific and technical leadership for real-world evidence (RWE) studies supporting post-market regulatory requirements, reimbursement, clinical evidence generations, and pre-market submissions across Abbott’s Electrophysiology portfolio. This individual will lead the design, execution, and dissemination of observational studies using large-scale real-world data sources, including electronic health records (EHR), insurance claims, hospital administrative and billing databases, and device-generated data.
What You’ll Work On
Real-World Evidence Study Leadership
- Lead the design and execution of real-world evidence, health economics, and digital health studies related to Abbott medical devices, using real-world data sources such as electronic health records, insurance claims, and hospital administrative/billing databases.
- Develop and own RWE study protocols and statistical analysis plans (SAPs) aligned with regulatory, clinical, and reimbursement objectives.
- Build and help execute long-term RWE generation strategies across the electrophysiology portfolio, in collaboration with clinical, regulatory, medical affairs, and market access stakeholders.
Data Analysis & Programming
- Perform hands-on programming to execute RWE studies using SQL, R, SAS, Python, or similar languages.
- Manage data preparation, cohort construction, variable derivation, and analysis across diverse data types, including EHR data, insurance claims, hospital billing data, device-generated data, and clinical trial data.
- Partner closely with data analysts and data engineers to validate programming logic, analytical datasets, and study results, ensuring accuracy, reproducibility, and regulatory readiness.
Scientific Communication & Disclosure
- Lead development of study reports, regulatory deliverables, conference abstracts, podium and poster presentations, and peer-reviewed scientific manuscripts.
- Translate complex analytical results into clear, clinically meaningful scientific narratives for internal leadership, regulators, clinicians, and external stakeholders.
Clinical & Therapeutic Area Expertise
- Maintain strong and up-to-date knowledge of the clinical landscape in cardiac electrophysiology, including atrial fibrillation, atrial flutter, ventricular arrhythmias, ablation technologies, and evolving standards of care.
- Monitor emerging evidence, clinical guidelines, competitive technologies, and unmet clinical needs to inform RWE study design, endpoint selection, and evidence generation strategy.
- Apply clinical context to interpret real-world data results, assess relevance to intended use populations, and support regulatory and clinical decision-making.
Cross-Functional Collaboration
- Collaborate effectively with peers across biostatistics, clinical affairs, regulatory affairs, medical affairs, health economics, and R&D teams.
- Represent RWE and observational research perspectives in cross-functional project teams and strategy discussions.
- Engage with external collaborators, including academic researchers, data vendors, and clinical experts, as appropriate.
Required Qualifications
- Associates Degree
- 4 years related experience
Preferred Qualifications
- Master's Degree with 4+ years of related experience OR Bachelor's Degree with 6-8 years of related experience OR an equivalent combination of education and work experience.
- PhD, DrPH, PharmD, MS, or equivalent advanced degree in biostatistics, epidemiology, clinical research, public health, outcomes research, biomedical engineering, or a related field. 2-5+ years’ Experience leading real-world evidence, observational research, or outcomes research studies in the medical device, pharmaceutical, or life sciences industry, with increasing levels of scientific responsibility.
- Experience designing and executing regulatory-grade clinical studies or RWE studies.
- Strong expertise working with large real-world datasets, including electronic health records, administrative claims data, hospital billing/chargemaster data, registries, and/or device-generated data.
- Advanced hands-on experience in statistical programming and data analysis using one or more of the following: SQL, R, SAS, Python (or equivalent), with the ability to independently execute complex cohort-based analyses.
- Deep understanding of epidemiologic study design and analytical methods for observational research, including cohort studies, comparative effectiveness research, signal detection, sensitivity analyses, and bias mitigation strategies.
- Proven ability to develop RWE protocols and statistical analysis plans suitable for regulatory review, including clear articulation of study objectives, endpoints, data sources, and analytical approaches.
- Familiarity with regulatory and methodological guidance relevant to real-world evidence, including FDA expectations for data relevance, reliability, and transparency.
- Prior experience leading the development of study reports, regulatory submissions, peer-reviewed manuscripts, conference abstracts, and scientific presentations.
- Background or strong working knowledge of the cardiac electrophysiology therapeutic area, including atrial fibrillation, atrial flutter, ventricular arrhythmias, catheter ablation technologies, and evolving standards of care, with the ability to interpret results in a clinically meaningful context.
- Demonstrated ability to stay current with the clinical and competitive landscape in electrophysiology, including emerging technologies, clinical guidelines, and real-world evidence trends.
- Experience collaborating effectively with cross-functional teams (e.g., clinical affairs, regulatory affairs, medical affairs, health economics, data science, biostatistics) and influencing without formal authority.
- Demonstrated ability to manage multiple complex projects simultaneously, prioritize effectively, and deliver high-quality scientific work under tight timelines, with strong attention to detail and commitment to analytical rigor.
- Strong scientific communication skills, with the ability to translate complex analyses into clear, actionable insights for diverse audiences, including clinicians, regulators, and internal leadership.
- Experience working with external collaborators such as academic investigators, data vendors, or health system partners is preferred.
Apply Now
Learn more about our health and wellness benefits, which provide the security to help you and your family live full lives: www.abbottbenefits.com
Follow your career aspirations to Abbott for diverse opportunities with a company that can help you build your future and live your best life.
Abbott is an Equal Opportunity Employer, committed to employee diversity.
The base pay for this position is $90,000.00 – $180,000.00. In specific locations, the pay range may vary from the range posted.
See all 209+ Senior Clinical Research Scientist jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Senior Clinical Research Scientist roles.
Get Access To All JobsTips for Finding Green Card Sponsorship as a Senior Clinical Research Scientist
Document your protocol authorship before applying
PERM audits for Clinical Research Scientist roles often scrutinize whether your credentials match the job requirements. Compile evidence of protocols you've authored, INDs or NDAs you've contributed to, and any regulatory submissions you've supported before your employer files.
Target sponsors with existing PERM filing infrastructure
Large pharma companies, CROs, and academic medical centers already have immigration counsel and established PERM processes. Smaller biotech startups may be willing to sponsor but lack the infrastructure, which can add months to your timeline and increase audit risk.
Search for sponsoring employers using Migrate Mate
Use Migrate Mate to filter Senior Clinical Research Scientist roles by employers with active green card filing history. This lets you focus applications on organizations that already understand PERM and I-140 timelines rather than educating employers from scratch.
Confirm the prevailing wage tier before your offer
Your employer's PERM labor certification must certify a wage at or above the DOL prevailing wage for your specific job zone and location. Use the OFLC Wage Search to check the wage level independently and ensure your offered salary meets the requirement before you accept.
Negotiate a clear sponsorship commitment in your offer letter
Ask your employer to specify in writing that they will initiate PERM within a set timeframe, typically within your first year. Without this, some employers delay filing indefinitely, which matters if your current work authorization has an expiration date.
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Find Senior Clinical Research Scientist JobsSenior Clinical Research Scientist Green Card Sponsorship: Frequently Asked Questions
Does a Senior Clinical Research Scientist role typically qualify for EB-2 or EB-3 green card sponsorship?
Most Senior Clinical Research Scientist positions qualify for EB-2 because they routinely require a master's degree or Ph.D. in a life sciences field. If your employer's job description specifies an advanced degree as a minimum requirement and your credentials match, USCIS will generally classify the petition under EB-2. Roles requiring only a bachelor's degree fall under EB-3 skilled worker.
How does green card sponsorship differ from H-1B sponsorship for this role?
H-1B is a temporary status with a three-year initial period and annual lottery exposure. Green card sponsorship through PERM leads to permanent residency with no renewal risk. The EB-3 category has no annual cap on petitions filed, though visa number availability varies by nationality. The process takes longer, typically two to four years from PERM filing to approval for most applicants, but the outcome is permanent.
What makes a PERM application for a Clinical Research Scientist role vulnerable to a DOL audit?
Audits often trigger when the job description includes requirements that appear tailored to the foreign worker specifically, such as experience with a proprietary clinical data system used only by that employer. DOL also flags unusual combinations of degree requirements and experience levels. Keeping job requirements consistent with what you'd ask of any qualified hire reduces audit exposure.
How can I find employers who actively sponsor green cards for this role?
Migrate Mate lets you search Senior Clinical Research Scientist roles filtered by employers with documented green card and PERM filing history. This removes guesswork and lets you prioritize applications to organizations that already have immigration processes in place, rather than those that might be open to sponsorship in principle but have never filed.
Can I switch employers after my PERM is approved but before I receive my green card?
Yes, under AC21 portability rules, if your I-140 has been approved and your I-485 adjustment of status application has been pending for 180 days or more, you can move to a new employer in a same or similar occupational classification. For Senior Clinical Research Scientists, a comparable role at another pharma or CRO employer generally qualifies, but you should consult an immigration attorney before making that move.
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