Head Of Engineering Jobs in San Francisco, CA
Head Of Engineering jobs in San Francisco are concentrated in SoMa, Mission Bay, and the Financial District, with strong demand from employers in enterprise software, cloud infrastructure, fintech, and biotech. Companies actively hiring include HARVEY, Gamut, and Heidi. Scan the live roles below and apply to whichever ones fit.
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Head of Engineering Gaia Health
Full-time, San Francisco
About the Role
Gaia is a consumer health company re-defining our experience with medicine across the whole stack. We have created technological breakthroughs in drug delivery technology that enable once monthly controlled-release of medicines rather than needing daily pills, and alongside this we’re building a tech platform for personalized medicine.
Gaia is hiring a founding Head of Engineering to build the technical backbone of the system that enables personalized medicine. You'll design and build our platform — the patient and physician experiences, the data infrastructure, and the integrations that connect our products to the broader healthcare ecosystem — and hire the team that grows it with you. We believe in building things the right way: patient trust comes first, compliance is architecture rather than paperwork, and the systems we ship deserve the same craft as the medicine they support.
What You'll Own
The platform: backend, data infrastructure, and patient- and physician-facing web and app experiences, built hands-on
Integrations with our pharmacy, clinical, diagnostic, and wearable partners — each one expanding what our platform can do for patients
HIPAA-first compliance architecture and the company's standards for safe, effective AI –
Hiring and leading the engineering team, setting the engineering culture from day one –
Deep partnership with our product lead and design team — interface quality is an engineering concern here
Championing AI-native ways of working across the company
What You'll Bring
8+ years of engineering experience, including leading engineers, and the hands-on range to architect and build across the stack today
Production experience with sensitive or regulated data, and third-party integrations that held up in the real world
A record of shipping fast in zero-to-one environments while making deliberate build-vs-buy and technical-debt decisions
Product sensibility, genuine collaboration with design, and clear written communication
Self-awareness, low ego, and the instinct to bring in experts early
Preferred: Healthcare experience (FHIR, e-prescribing, telehealth, wearables) and shipped AI/LLM features are a plus — patient-trust instincts are a must
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Who's Hiring



Top Industries Hiring
- Technology & Software12
- Energy2
- Banking & Financial Services2
- Investment & Asset Management2
Head Of Engineering Jobs in San Francisco: Frequently Asked Questions
How do I get a head of engineering job in San Francisco?
Focus your search on San Francisco's dense clusters of enterprise software, fintech, and biotech companies in SoMa, Mission Bay, and the Financial District. Employers here prioritize candidates who can own technical roadmaps and translate engineering output into business outcomes. Experience scaling distributed systems or managing platform infrastructure gives you a clear edge over generalist candidates in this market.
Which companies hire head of engineerings in San Francisco?
Companies currently hiring head of engineerings in San Francisco include HARVEY, Gamut, and Heidi, per current listings on Migrate Mate as of August 2026. San Francisco's employer base skews heavily toward venture-backed technology companies and established enterprise software firms, so openings tend to cluster around Series B through public-stage organizations.
Are there remote head of engineering jobs in San Francisco?
Yes, though the role is moderately remote-friendly since it requires close coordination with product, design, and executive teams. About 50% of head of engineering openings tied to San Francisco are remote or hybrid as of August 2026, with hybrid arrangements being far more common than fully remote. Strategic and architectural responsibilities tend to be easier to perform remotely than hands-on team leadership duties.
How can I get a head of engineering job in San Francisco with little or no experience?
The most realistic path is moving into a senior staff or principal engineering role at a mid-size San Francisco company first, then stepping into an engineering manager position before targeting head-level roles. Startups in SoMa and Mission Bay often promote from within and give strong individual contributors early people-management scope. Demonstrating ownership of a product area, even informally, strengthens your candidacy significantly.
Which industries hire the most head of engineerings in San Francisco?
Most head of engineering openings in San Francisco sit in Technology & Software, Energy, and Banking & Financial Services, per current listings on Migrate Mate as of August 2026. San Francisco's concentration of cloud-native software companies, financial technology platforms, and life sciences firms makes it one of the densest markets in the country for engineering leadership roles.
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