Head Of Engineering Jobs
Head Of Engineering jobs are open across tech, fintech, healthtech, and enterprise software, from senior engineering manager to VP-level, with specializations in platform engineering, infrastructure, and full-stack product development. Find a role that fits from the openings below and apply directly.
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About us
iota Biosciences, a wholly owned subsidiary of Astellas Pharma US, is advancing a new class of bioelectronic medicines through the development of fully implantable Class III medical devices. Our proprietary technologies open therapeutic and diagnostic possibilities not previously accessible to clinicians. Together with Astellas, we are committed to patient-centric design, scientific and engineering excellence, and cross-functional teamwork. These principles guide us in bringing transformative, first-of-its-kind technologies into the clinic and closer to patients.
Role Overview
The Head of Engineering reports directly to the CEO and serves as the company's senior engineering leader and strategic advisor. This role is responsible for ensuring that engineering, manufacturing, and product development efforts are aligned with the company's clinical, regulatory, and commercialization objectives. The Head of Engineering will partner closely with the CEO and executive team to guide major company decisions, assess risks and dependencies, and help the organization navigate the transition from clinical-stage development through PMA and early commercialization. The successful candidate will inherit a strong engineering leadership team and will be expected to elevate organizational effectiveness, strengthen cross-functional execution, and provide experienced leadership through a critical stage of growth. Success in this role will come not from direct ownership of technical architecture, but from enabling strong decision-making across the organization, connecting work across engineering functions, and helping leaders anticipate challenges before they become obstacles. This individual should bring firsthand experience developing and bringing medical devices through PMA pathways, allowing them to provide perspective, identify risks and opportunities, and help the company make informed strategic and long-term investments.
Executive Leadership and Strategic Partnership
- Serve as a trusted advisor to the CEO and Executive Team, helping translate complex engineering and product development topics into actionable business decisions.
- Provide independent judgment on major company decisions, investments, risks, resource allocation, and strategic priorities.
- Represent engineering perspectives in executive, investor, partner, and board-level discussions as appropriate.
- Help the organization make sound tradeoffs between technical risk, regulatory requirements, timelines, cost, manufacturing readiness, and long-term platform strategy.
- Partner with executive leadership to shape product portfolio strategy and roadmap planning, ensuring alignment between near-term milestones and long-term company objectives.
Engineering Leadership
- Lead and further develop iota's engineering leadership team across electrical, firmware, software, systems, mechanical, and manufacturing engineering.
- Provide coaching, mentorship, and leadership support to an already strong group of engineering leaders, helping elevate organizational effectiveness and execution.
- Ensure alignment across engineering functions by identifying dependencies, surfacing risks early, and facilitating effective decision-making.
- Establish clear expectations, accountability, communication, and decision-making frameworks across the engineering organization.
- Partner with engineering leaders to ensure teams remain focused on company priorities while preserving clear ownership of architecture and day-to-day technical decisions within each function.
- Build strong, trusted relationships with engineering leaders and key cross-functional stakeholders.
Product Development, Regulatory, and Commercialization Execution
- Guide engineering activities supporting pivotal clinical studies, PMA submission, approval, and commercialization readiness.
- Leverage prior PMA experience to help the organization anticipate challenges, evaluate tradeoffs, and make informed decisions throughout the product lifecycle.
- Ensure appropriate engineering rigor, design controls, risk management, verification, validation, and development processes are in place.
- Partner closely with Quality, Regulatory, Clinical, Operations, Manufacturing, and Program/Product Management leaders to drive successful execution.
- Support commercialization planning and manufacturing scale-up activities while maintaining product quality and regulatory compliance.
Organizational Development
- Mentor and develop engineering leaders and high-potential talent.
- Build organizational capabilities that scale with company growth.
- Create succession plans and leadership development pathways within the engineering organization.
- Foster a culture of accountability, collaboration, transparency, and continuous improvement.
Required Qualifications
- BS in Engineering or related technical field.
- Willingness to work from our Alameda office approximately three days per week.
- Significant experience developing and bringing medical devices through PMA pathways, with the ability to apply those lessons to strategic planning, risk management, and organizational decision-making.
- Proven success leading multidisciplinary engineering organizations in regulated medical device environments.
- Demonstrated ability to develop strong engineering leaders.
- Strong communication, stakeholder management, and organizational leadership skills.
- Demonstrated ability to build trust and influence across technical and non-technical teams.
- Experience balancing innovation with regulatory, quality, clinical, and business requirements.
- Ability to understand and connect work across multiple engineering disciplines, identify dependencies and risks, and drive alignment across teams.
Preferred Qualifications
- Global regulatory experience, including CE Mark and MDR.
- Experience operating in fast-paced, resource-constrained environments where leaders are expected to navigate ambiguity, solve novel problems, and take ownership beyond traditional functional boundaries.
Why Join Us
This is a rare opportunity to help shape the future of bioelectronic medicine at a pivotal moment in the company's journey. You will partner directly with the CEO and executive team, guide critical organizational and strategic decisions, help prepare the company for its next phase of growth, and contribute to the development of therapies that have the potential to transform patients' lives. At iota, you'll join a mission-driven team tackling some of the most challenging problems in medicine through a unique combination of scientific innovation, engineering excellence, and patient-centered design.
Compensation Range: $230K - $311K
About us
iota Biosciences, a wholly owned subsidiary of Astellas Pharma US, is advancing a new class of bioelectronic medicines through the development of fully implantable Class III medical devices. Our proprietary technologies open therapeutic and diagnostic possibilities not previously accessible to clinicians. Together with Astellas, we are committed to patient-centric design, scientific and engineering excellence, and cross-functional teamwork. These principles guide us in bringing transformative, first-of-its-kind technologies into the clinic and closer to patients.
Role Overview
The Head of Engineering reports directly to the CEO and serves as the company's senior engineering leader and strategic advisor. This role is responsible for ensuring that engineering, manufacturing, and product development efforts are aligned with the company's clinical, regulatory, and commercialization objectives. The Head of Engineering will partner closely with the CEO and executive team to guide major company decisions, assess risks and dependencies, and help the organization navigate the transition from clinical-stage development through PMA and early commercialization. The successful candidate will inherit a strong engineering leadership team and will be expected to elevate organizational effectiveness, strengthen cross-functional execution, and provide experienced leadership through a critical stage of growth. Success in this role will come not from direct ownership of technical architecture, but from enabling strong decision-making across the organization, connecting work across engineering functions, and helping leaders anticipate challenges before they become obstacles. This individual should bring firsthand experience developing and bringing medical devices through PMA pathways, allowing them to provide perspective, identify risks and opportunities, and help the company make informed strategic and long-term investments.
Executive Leadership and Strategic Partnership
- Serve as a trusted advisor to the CEO and Executive Team, helping translate complex engineering and product development topics into actionable business decisions.
- Provide independent judgment on major company decisions, investments, risks, resource allocation, and strategic priorities.
- Represent engineering perspectives in executive, investor, partner, and board-level discussions as appropriate.
- Help the organization make sound tradeoffs between technical risk, regulatory requirements, timelines, cost, manufacturing readiness, and long-term platform strategy.
- Partner with executive leadership to shape product portfolio strategy and roadmap planning, ensuring alignment between near-term milestones and long-term company objectives.
Engineering Leadership
- Lead and further develop iota's engineering leadership team across electrical, firmware, software, systems, mechanical, and manufacturing engineering.
- Provide coaching, mentorship, and leadership support to an already strong group of engineering leaders, helping elevate organizational effectiveness and execution.
- Ensure alignment across engineering functions by identifying dependencies, surfacing risks early, and facilitating effective decision-making.
- Establish clear expectations, accountability, communication, and decision-making frameworks across the engineering organization.
- Partner with engineering leaders to ensure teams remain focused on company priorities while preserving clear ownership of architecture and day-to-day technical decisions within each function.
- Build strong, trusted relationships with engineering leaders and key cross-functional stakeholders.
Product Development, Regulatory, and Commercialization Execution
- Guide engineering activities supporting pivotal clinical studies, PMA submission, approval, and commercialization readiness.
- Leverage prior PMA experience to help the organization anticipate challenges, evaluate tradeoffs, and make informed decisions throughout the product lifecycle.
- Ensure appropriate engineering rigor, design controls, risk management, verification, validation, and development processes are in place.
- Partner closely with Quality, Regulatory, Clinical, Operations, Manufacturing, and Program/Product Management leaders to drive successful execution.
- Support commercialization planning and manufacturing scale-up activities while maintaining product quality and regulatory compliance.
Organizational Development
- Mentor and develop engineering leaders and high-potential talent.
- Build organizational capabilities that scale with company growth.
- Create succession plans and leadership development pathways within the engineering organization.
- Foster a culture of accountability, collaboration, transparency, and continuous improvement.
Required Qualifications
- BS in Engineering or related technical field.
- Willingness to work from our Alameda office approximately three days per week.
- Significant experience developing and bringing medical devices through PMA pathways, with the ability to apply those lessons to strategic planning, risk management, and organizational decision-making.
- Proven success leading multidisciplinary engineering organizations in regulated medical device environments.
- Demonstrated ability to develop strong engineering leaders.
- Strong communication, stakeholder management, and organizational leadership skills.
- Demonstrated ability to build trust and influence across technical and non-technical teams.
- Experience balancing innovation with regulatory, quality, clinical, and business requirements.
- Ability to understand and connect work across multiple engineering disciplines, identify dependencies and risks, and drive alignment across teams.
Preferred Qualifications
- Global regulatory experience, including CE Mark and MDR.
- Experience operating in fast-paced, resource-constrained environments where leaders are expected to navigate ambiguity, solve novel problems, and take ownership beyond traditional functional boundaries.
Why Join Us
This is a rare opportunity to help shape the future of bioelectronic medicine at a pivotal moment in the company's journey. You will partner directly with the CEO and executive team, guide critical organizational and strategic decisions, help prepare the company for its next phase of growth, and contribute to the development of therapies that have the potential to transform patients' lives. At iota, you'll join a mission-driven team tackling some of the most challenging problems in medicine through a unique combination of scientific innovation, engineering excellence, and patient-centered design.
Compensation Range: $230K - $311K
See All 162+ Head Of Engineering Jobs
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Find Head Of Engineering JobsHead Of Engineering Job Market
A snapshot from current openings nationwide, updated as new roles post.
Who's Hiring
- State Street7
- SentiLink6
- Socure5
- BlackRock4
- Citi4
Top Industries Hiring
- Technology & Software56
- Investment & Asset Management20
- Banking & Financial Services18
- Biotechnology & Pharmaceuticals18
- Electronics & Hardware10
What Employers Look For
The qualifications that appear most often in head of engineering jobs.
- 10 or more years of software engineering experience with at least 5 in engineering leadership
- Proven experience managing managers and building high-performing engineering teams
- Strong command of software architecture, system design, and technical roadmapping
- Experience partnering with product, design, and business stakeholders on delivery planning
- Familiarity with agile or other iterative development methodologies and engineering metrics
- Bachelor's degree in computer science, software engineering, or a related technical field
Tips for Your Head Of Engineering Job Search
Quantify engineering org impact clearly
Your resume should show how many engineers you've led, how team size changed under your leadership, and how delivery metrics shifted. Hiring committees for head of engineering roles want evidence of org-level outcomes, not just project ownership.
Tailor your story to company stage
A Series B startup wants someone who can build hiring pipelines from scratch. A public company wants process maturity and cross-functional alignment. Read the job description for signals like 'scrappy,' 'scale,' or 'standardize' and mirror that language in your application.
Apply early to roles that fit
Migrate Mate lists head of engineering openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Prepare a technical credibility narrative
You'll be asked how long ago you last wrote production code and how you stay current. Have a concrete answer ready: specific languages, recent architectural decisions you influenced, or how you run technical reviews with your staff engineers.
Research the engineering org before interviewing
Check engineering blogs, conference talks, and public GitHub repos tied to the company. Knowing their stack, current scaling challenges, or recent architectural shifts lets you ask sharper questions and signal genuine interest in their specific problems.
Negotiate scope before negotiating compensation
Before accepting an offer, clarify reporting structure, budget authority, and which decisions you own versus which require executive sign-off. Misaligned scope is the most common reason heads of engineering leave within the first year.
Head Of Engineering Jobs: Frequently Asked Questions
Which companies are hiring the most head of engineerings?
The companies hiring the most head of engineerings right now include State Street, SentiLink, and Socure, with the largest share of openings in California, New York, and Massachusetts, based on current listings on Migrate Mate as of June 2026. Demand is strongest at growth-stage startups and mid-market technology companies expanding their engineering orgs.
How many head of engineering jobs are remote?
About 31% of head of engineering openings are fully remote or hybrid as of June 2026, making it one of the more flexible senior leadership roles in the market. Platform engineering, infrastructure, and back-end-focused roles tend to offer the highest share of remote flexibility compared to roles tied to in-person hardware or lab environments.
How do you become a head of engineering?
Most heads of engineering move up through staff or principal engineer roles, then into engineering manager and director positions before stepping into a head-level seat. The path requires demonstrating that you can develop managers, own a technical roadmap, and influence product direction. Building cross-functional relationships with product and design leaders accelerates the transition, as does taking ownership of hiring and team structure early.
Can you get hired as a head of engineering with limited leadership experience?
It's possible at smaller companies or early-stage startups where the role is being created rather than backfilled. Candidates who have led a full engineering team through a product launch, even informally, have a stronger case than those with only individual contributor experience. Highlighting decisions you owned, engineers you mentored, and processes you introduced matters more than your official title history.
What does the head of engineering interview process look like?
The process typically runs across four to six rounds. Early stages include a recruiter screen and a hiring manager conversation focused on leadership philosophy and career trajectory. Later rounds involve system design or architecture discussions, a presentation on how you'd approach the first ninety days, and panel interviews with product, design, and executive stakeholders. References and a final executive conversation are common at the close.
Where can I find and apply to head of engineering jobs?
You can find and apply to head of engineering jobs on Migrate Mate, which lists current openings from across the United States. Search the listings to find roles that match your experience and seniority level, then apply directly to each one that fits.
See All 162+ Head Of Engineering Jobs
Jump back to the full list of openings and apply to any head of engineering role that fits.
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