Senior Level Informatics Nurse Jobs

Senior level informatics nurse jobs place experienced clinicians in charge of system architecture decisions, implementation outcomes, and the teams translating clinical needs into technology solutions. Openings are concentrated across Insurance, Healthcare & Medical Services, and Education, with a mix of on-site, remote, and hybrid settings, and employers like CVS Health, Sutter Health, and Community Health Systems hiring at this level now.

Find Jobs

Overview

Open roles22
Top stateCalifornia
Top employerCVS Health
Top citySacramento, CA
Work type58% Hybrid
Top industryInsurance

Showing 5 of 22+ Senior Level Informatics Nurse jobs

Senior Manager Informatics, Salesforce Analytics
We won't show you this job again
Added 1mo ago
Senior Manager Informatics, Salesforce Analytics
CVS Health
Providence, Rhode Island
Business Analysis
Data Science & Analytics
Project & Program Management
Revenue Operations & Enablement
$68k - $199k/yr
Hybrid
Bachelor's
10,000+

Have you applied for this role?

Senior Manager Informatics, Performance Analytics
We won't show you this job again
Added 1mo ago
Senior Manager Informatics, Performance Analytics
CVS Health
Madison, Wisconsin
Business Analysis
Data Science & Analytics
Partnerships & Business Development
Data Science
Data Analytics
Revenue Operations & Enablement
$68k - $199k/yr
Hybrid
Bachelor's
10,000+

Have you applied for this role?

Senior Manager Informatics, Performance Analytics
We won't show you this job again
Added 1mo ago
Senior Manager Informatics, Performance Analytics
CVS Health
Dover, Delaware
Business Analysis
Data Science & Analytics
Project & Program Management
Revenue Operations & Enablement
$68k - $199k/yr
Hybrid
Bachelor's
10,000+

Have you applied for this role?

Senior Manager Informatics, Salesforce Analytics
We won't show you this job again
Added 1mo ago
Senior Manager Informatics, Salesforce Analytics
CVS Health
Austin, Texas
Business Analysis
Data Science & Analytics
Project & Program Management
Revenue Operations & Enablement
$68k - $199k/yr
Hybrid
Bachelor's
10,000+

Have you applied for this role?

Senior Manager Informatics, Salesforce Analytics
We won't show you this job again
Added 1mo ago
Senior Manager Informatics, Salesforce Analytics
CVS Health
Cheyenne, Wyoming
Business Analysis
Data Science & Analytics
Partnerships & Business Development
Data Science
Data Analytics
Business Development
Revenue Operations & Enablement
$68k - $199k/yr
Hybrid
Bachelor's
10,000+

Have you applied for this role?

See All 22 Senior Level Informatics Nurse Jobs

Find roles that match your experience and apply in just a few clicks.

Find Jobs

Senior Level Informatics Nurse Job Market

Who's Hiring

  • CVS Health11
  • Sutter Health2
  • Community Health Systems2
  • Revolution Medicines2
  • UTHealth Houston1

Top Industries Hiring

  • Insurance11
  • Healthcare & Medical Services6
  • Education2
  • Biotechnology & Pharmaceuticals2
  • Medical Devices1

Senior Level Informatics Nurse Jobs: Frequently Asked Questions

How do I get a senior level informatics nurse job?

Employers at this level look for candidates who have owned full implementation cycles, not just supported them. Demonstrating that you have led system builds, guided clinical workflows, and mentored junior staff gives you a clear edge. Certifications like the Registered Nurse Informatics Certification (RN-BC) signal commitment to the specialty, and a portfolio of measurable outcomes, such as improved adoption rates or reduced documentation errors, strengthens your case considerably.

Which companies hire senior level informatics nurses?

Companies hiring senior level informatics nurses right now include CVS Health, Sutter Health, and Community Health Systems, based on current listings on Migrate Mate as of November 2026. At this level, hiring comes from large health systems, integrated delivery networks, and health IT vendors that need experienced clinicians to lead enterprise-wide initiatives.

Are there remote senior level informatics nurse jobs?

Yes, though availability varies by employer and project phase. About 58% of senior level informatics nurse openings are remote or hybrid as of November 2026, reflecting how much of this work centers on system configuration, training design, and stakeholder communication rather than bedside care. Implementation phases that require on-site presence are the most common exception.

What makes an informatics nurse role senior level?

Senior level roles are defined by ownership and scope rather than task execution. You are expected to set the clinical direction for technology projects, make architecture and workflow decisions independently, and be accountable for outcomes across departments or facilities. Mentoring junior informatics staff and serving as a liaison between clinical leadership and IT are core responsibilities, not occasional duties.

Which industries hire the most senior level informatics nurses?

Senior level informatics nurse roles concentrate in Insurance, Healthcare & Medical Services, and Education, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because they operate at the scale where dedicated clinical informatics leadership has a direct impact on care quality, regulatory compliance, and technology ROI.