Senior Level Information Systems Analyst Jobs
Senior level information systems analyst jobs place experienced analysts in charge of enterprise architecture decisions, system integration roadmaps, and the cross-functional projects that translate business strategy into working technology. Hiring is concentrated across Technology & Software, Education, and Consulting & Professional Services, with 67% of openings offering remote or hybrid arrangements and employers like MTSI, GRVTY, and VTG Defense hiring at this level now.
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Showing 4 of 11+ Senior Level Information Systems Analyst jobs
WHY UT SOUTHWESTERN?
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you’ll discover a culture of teamwork, professionalism, and a rewarding career!
JOB SUMMARY
The Laboratory Information Systems (LIS) Manager is responsible for the strategic leadership, operational management, governance, implementation, and support of laboratory information systems that enable Clinical Pathology, Anatomic Pathology, Blood Bank, and related laboratory services. This leadership role ensures the effective delivery, optimization, and compliance of laboratory technology solutions that support high-quality patient care, operational excellence, and organizational objectives.
The Manager serves as the primary liaison between Information Resources (IR), Laboratory Services, Pathology Leadership, clinical and operational departments, executive stakeholders, and technology vendors. The role requires strong technical expertise, leadership skills, and the ability to manage complex initiatives in a highly regulated healthcare environment.
KEY RESPONSIBILITIES
- Provide strategic direction and operational oversight for all Laboratory Information Systems (LIS) and related applications.
- Lead the planning, implementation, optimization, and maintenance of laboratory technology solutions supporting Clinical Pathology, Anatomic Pathology, Blood Bank, and outreach laboratory operations.
- Establish and oversee governance processes, prioritization frameworks, and project portfolios related to LIS initiatives.
- Partner with laboratory leadership, pathologists, clinicians, and operational stakeholders to identify technology needs and implement effective solutions.
- Ensure system reliability, performance, availability, security, and scalability across laboratory applications.
- Direct and manage complex projects, including system upgrades, implementations, integrations, workflow enhancements, and regulatory initiatives.
- Oversee vendor relationships, contract performance, and service delivery to ensure organizational expectations are met.
- Ensure compliance with applicable regulatory and accreditation standards, including CAP, CLIA, FDA, HIPAA, and other healthcare requirements.
- Develop and maintain policies, procedures, and standards related to laboratory information systems and data management.
- Lead risk assessment, change management, testing, validation, and issue resolution processes for laboratory technology systems.
- Monitor key performance indicators and drive continuous improvement initiatives to enhance operational efficiency and user satisfaction.
- Manage, mentor, and develop LIS team members while fostering a culture of collaboration, accountability, and innovation.
BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare - no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
EXPERIENCE AND EDUCATION
Required
Education
High School Diploma or equivalent or
Bachelor’s Degree with major coursework in computer science, math, information systems, or other related field
Experience
8 years progressively responsible and applicable information technology experience with High School Diploma including 2 years in supervisory or managerial role or
6 years progressively responsible information technology experience with Bachelor’s Degree including 2 years in supervisory or managerial role
JOB DUTIES
- Manages Information Resources section, such as Network Services, Software Systems Programming, Computer Training, etc. following university policies and procedures and using effective management, communication, and customer service skills to develop and ensure effective program.
- Develops, revises, recommends, and interprets policies and procedures for section to ensure all applicable laws and governmental guidelines are followed and that employees are treated in equitable manner.
- Coordinates various projects and programs for section ensuring all tasks are completed by established deadlines and to ensure that quality customer service is provided for faculty and staff.
- Assists campus departments in assessing technical requirements that meet needs of their operation.
- Completes work specific to assigned section using appropriate technologies and communication skills.
- Supervises group of professional and/or administrative support employees.
- Performs other duties as assigned.
SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. To the extent this position requires the holder to research, work on, or have access to critical infrastructure as defined in Section 117.001(2) of the Texas Business and Commerce Code, the ability to maintain the security or integrity of the critical infrastructure is a minimum qualification to be hired and to continue to be employed in the position.
EEO
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
WHY UT SOUTHWESTERN?
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you’ll discover a culture of teamwork, professionalism, and a rewarding career!
JOB SUMMARY
The Laboratory Information Systems (LIS) Manager is responsible for the strategic leadership, operational management, governance, implementation, and support of laboratory information systems that enable Clinical Pathology, Anatomic Pathology, Blood Bank, and related laboratory services. This leadership role ensures the effective delivery, optimization, and compliance of laboratory technology solutions that support high-quality patient care, operational excellence, and organizational objectives.
The Manager serves as the primary liaison between Information Resources (IR), Laboratory Services, Pathology Leadership, clinical and operational departments, executive stakeholders, and technology vendors. The role requires strong technical expertise, leadership skills, and the ability to manage complex initiatives in a highly regulated healthcare environment.
KEY RESPONSIBILITIES
- Provide strategic direction and operational oversight for all Laboratory Information Systems (LIS) and related applications.
- Lead the planning, implementation, optimization, and maintenance of laboratory technology solutions supporting Clinical Pathology, Anatomic Pathology, Blood Bank, and outreach laboratory operations.
- Establish and oversee governance processes, prioritization frameworks, and project portfolios related to LIS initiatives.
- Partner with laboratory leadership, pathologists, clinicians, and operational stakeholders to identify technology needs and implement effective solutions.
- Ensure system reliability, performance, availability, security, and scalability across laboratory applications.
- Direct and manage complex projects, including system upgrades, implementations, integrations, workflow enhancements, and regulatory initiatives.
- Oversee vendor relationships, contract performance, and service delivery to ensure organizational expectations are met.
- Ensure compliance with applicable regulatory and accreditation standards, including CAP, CLIA, FDA, HIPAA, and other healthcare requirements.
- Develop and maintain policies, procedures, and standards related to laboratory information systems and data management.
- Lead risk assessment, change management, testing, validation, and issue resolution processes for laboratory technology systems.
- Monitor key performance indicators and drive continuous improvement initiatives to enhance operational efficiency and user satisfaction.
- Manage, mentor, and develop LIS team members while fostering a culture of collaboration, accountability, and innovation.
BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:
- PPO medical plan, available day one at no cost for full-time employee-only coverage
- 100% coverage for preventive healthcare - no copay
- Paid Time Off, available day one
- Retirement Programs through the Teacher Retirement System of Texas (TRS)
- Paid Parental Leave Benefit
- Wellness programs
- Tuition Reimbursement
- Public Service Loan Forgiveness (PSLF) Qualified Employer
EXPERIENCE AND EDUCATION
Required
Education
High School Diploma or equivalent or
Bachelor’s Degree with major coursework in computer science, math, information systems, or other related field
Experience
8 years progressively responsible and applicable information technology experience with High School Diploma including 2 years in supervisory or managerial role or
6 years progressively responsible information technology experience with Bachelor’s Degree including 2 years in supervisory or managerial role
JOB DUTIES
- Manages Information Resources section, such as Network Services, Software Systems Programming, Computer Training, etc. following university policies and procedures and using effective management, communication, and customer service skills to develop and ensure effective program.
- Develops, revises, recommends, and interprets policies and procedures for section to ensure all applicable laws and governmental guidelines are followed and that employees are treated in equitable manner.
- Coordinates various projects and programs for section ensuring all tasks are completed by established deadlines and to ensure that quality customer service is provided for faculty and staff.
- Assists campus departments in assessing technical requirements that meet needs of their operation.
- Completes work specific to assigned section using appropriate technologies and communication skills.
- Supervises group of professional and/or administrative support employees.
- Performs other duties as assigned.
SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. To the extent this position requires the holder to research, work on, or have access to critical infrastructure as defined in Section 117.001(2) of the Texas Business and Commerce Code, the ability to maintain the security or integrity of the critical infrastructure is a minimum qualification to be hired and to continue to be employed in the position.
EEO
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
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Top Industries Hiring
- Technology & Software
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- Consulting & Professional Services
Senior Level Information Systems Analyst Jobs: Frequently Asked Questions
How do I get a senior level information systems analyst job?
Employers hiring at the senior level look for candidates who have owned full system lifecycles, not just contributed to them. Demonstrating that you have led requirements gathering, driven architecture decisions, and delivered measurable improvements to enterprise systems gives you a clear edge. Strong candidates also show experience mentoring junior analysts and communicating technical tradeoffs to non-technical stakeholders.
Which companies hire senior level information systems analysts?
Companies hiring senior level information systems analysts right now include MTSI, GRVTY, and VTG Defense, based on current listings on Migrate Mate as of November 2026. Hiring at this level tends to concentrate in large enterprises, government contractors, and consulting firms that maintain complex, mission-critical information systems requiring experienced oversight.
Are there remote senior level information systems analyst jobs?
Yes, remote and hybrid opportunities are well represented at this level. About 67% of senior level information systems analyst openings are remote or hybrid as of November 2026, reflecting how many organizations trust senior analysts to lead systems work independently. On-site roles are most common in sectors where security, compliance, or infrastructure access is required.
What makes an information systems analyst role senior level?
Senior level roles are defined by ownership and scope rather than task execution. A senior information systems analyst is expected to lead system design and integration initiatives, set technical standards for their team, and advise business leaders on technology investments. Mentoring analysts at earlier career stages and managing vendor or stakeholder relationships are also standard expectations at this level.
Which industries hire the most senior level information systems analysts?
Senior level information systems analyst roles concentrate in Technology & Software, Education, and Consulting & Professional Services, based on current listings on Migrate Mate as of November 2026. These sectors drive demand because they operate large, interconnected systems that require experienced analysts to maintain reliability, manage upgrades, and ensure alignment between technology capabilities and evolving business requirements.