Internal Medicine Nurse Practitioner Jobs in Missouri

Internal Medicine Nurse Practitioner jobs in Missouri are open across Chesterfield, St Louis, and Columbia and other Missouri metros, with employers like SSM Health, St. Luke's Hospital (MO), and Cox Monett Hospital hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles13+
Top employerSSM Health
Top cityChesterfield, MO
Cities hiring8
Work type100% On-site
Top industryHealthcare

Showing 5 of 13+ Internal Medicine Nurse Practitioner jobs

St. Luke's Hospital (MO)
Physician - Internal Medicine
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St. Luke's Hospital (MO)
Added 1mo ago
Physician - Internal Medicine
St. Luke's Hospital (MO)
Chesterfield, Missouri
Medical Specialists
Healthcare Administration
Physicians
Patient Services & Wellbeing
On-Site
Doctorate
1,001-5,000

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St. Luke's Hospital (MO)
Physician - Internal Medicine
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St. Luke's Hospital (MO)
Added 1mo ago
Physician - Internal Medicine
St. Luke's Hospital (MO)
Chesterfield, Missouri
Medical Specialists
Healthcare Administration
Physicians
Patient Services & Wellbeing
On-Site
Doctorate
1,001-5,000

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St. Luke's Hospital (MO)
Physician - Internal Medicine
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St. Luke's Hospital (MO)
Added 1mo ago
Physician - Internal Medicine
St. Luke's Hospital (MO)
Chesterfield, Missouri
Medical Specialists
Healthcare Administration
Physicians
Patient Services & Wellbeing
On-Site
Doctorate
1,001-5,000

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Mercy
Internal Medicine Residency Program Director
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Mercy
Added 1mo ago
Internal Medicine Residency Program Director
Mercy
Festus, Missouri
Nursing
Healthcare Administration
Medical Specialists
On-Site
None
10,000+

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Cox Monett Hospital Inc.
Medical Assistant III - Internal Medicine
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Cox Monett Hospital Inc.
Added 2mo ago
Medical Assistant III - Internal Medicine
Cox Monett Hospital Inc.
Springfield, Missouri
Clinical Support
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
On-Site
High School

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See All 13 Internal Medicine Nurse Practitioner Jobs in Missouri

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Internal Medicine Nurse Practitioner Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

Chesterfield
4 jobs
St Louis
3 jobs
Columbia
1 jobs
Fenton
1 jobs
Festus
1 jobs
Springfield
1 jobs
St Joseph
1 jobs
St. Louis
1 jobs

Internal Medicine Nurse Practitioner Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • SSM Health
    SSM Health5
  • St. Luke's Hospital (MO)
    St. Luke's Hospital (MO)3
  • Cox Monett Hospital
    Cox Monett Hospital1
  • Mercy
    Mercy1
  • Mosaic Life Care
    Mosaic Life Care1

Top Industries Hiring

  • Healthcare & Medical Services12
  • Education1
  • Insurance1

What Missouri Employers Look For

The qualifications that appear most often in internal medicine nurse practitioner jobs across Missouri.

  • Active APRN license with adult or family nurse practitioner board certification (ANCC or AANP)
  • Master of Science in Nursing or Doctor of Nursing Practice degree from an accredited program
  • DEA registration and state prescriptive authority for controlled substances
  • Minimum one to three years of clinical experience in internal medicine or primary care
  • Proficiency with electronic health record systems such as Epic, Cerner, or Meditech
  • Basic Life Support and Advanced Cardiovascular Life Support certification

Internal Medicine Nurse Practitioner Jobs in Missouri: Frequently Asked Questions

How many internal medicine nurse practitioner jobs are there in Missouri?

There are 13+ internal medicine nurse practitioner openings in Missouri on Migrate Mate as of June 2026, with the most roles in Chesterfield, St Louis, and Columbia. New positions post regularly as employers across Missouri hire.

How much do internal medicine nurse practitioners make in Missouri?

Internal medicine nurse practitioners in Missouri earn a median of about $129,930 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $100,650 for the lowest 10% to over $162,060 for the top 10%. Pay rises with experience, specialty, and employer.

Which Missouri cities have the most internal medicine nurse practitioner jobs?

Chesterfield, St Louis, and Columbia have the most internal medicine nurse practitioner openings in Missouri right now, with additional roles spread across smaller metros statewide.

Which companies hire internal medicine nurse practitioners in Missouri?

Employers hiring internal medicine nurse practitioners in Missouri include SSM Health, St. Luke's Hospital (MO), and Cox Monett Hospital, based on current listings on Migrate Mate as of June 2026.

Are there remote internal medicine nurse practitioner jobs in Missouri?

Yes. About 0% of internal medicine nurse practitioner openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.

How do I apply for internal medicine nurse practitioner jobs in Missouri?

You can apply to internal medicine nurse practitioner jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.

See All 13 Internal Medicine Nurse Practitioner Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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