Internal Medicine Nurse Practitioner Jobs
Internal Medicine Nurse Practitioner jobs are open across hospital systems, outpatient clinics, academic medical centers, and multi-specialty practices, from new-grad NP to experienced lead roles, with specializations in chronic disease management, primary care, and hospital medicine. Find a role that fits from the openings below and apply directly.
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Showing 5 of 20+ Internal Medicine Nurse Practitioner jobs











We Are Hiring:
Location: Indianapolis, Indiana
Facility Name: Heather Glenn Internal Medicine
Schedule: Full-Time | Monday - Friday 8:00 a.m. - 5:00 p.m.
What You Will Do:
This is an exceptional opportunity for a motivated advanced practice provider to join an employed position within a busy, well-respected practice, supported by a strong referral base and the full resources of a robust health system network.
- Call structure: Shared weekday and weekend on-call schedule rotation
- 100% Outpatient clinic featuring 26 dedicated exam rooms and a manageable expected patient volume of 12–15 patients per day.
- Access to advanced practice support resources and streamlined work-flows using the Athena EMR system.
- Employed position within a nonprofit health system
- Board Certified or Board Eligible in Nurse Practitioner
- Eligible for state medical licensure and DEA registration
- Enhance patient access through high-quality diagnostic and therapeutic evaluations for primary internal medicine conditions.
- Drive clinical excellence by actively participating in care quality and cost-effectiveness initiatives across the practice.
About the Facility
- The practice operates directly out of the high-functioning Heather Glenn Internal Medicine clinic on Naab Road, structurally integrated with the premier referral resources of Ascension St. Vincent Indianapolis.
- Ascension St. Vincent Indianapolis features an 86th Street campus anchored by an 821-bed acute care facility and 8 specialized Centers of Excellence, including a Level 1 Trauma Center.
- Serving a broad metropolitan Indianapolis population, providing an exceptional localized patient panel and strong multi-specialty network support.
- Integrated referral network
- Part of Ascension, a national nonprofit Catholic health system
Why Advanced Practice Providers Choose Ascension
- Physician-led, collaborative culture
- Long-term practice stability
- National network with local autonomy
- Mission-centered care rooted in service
What You Will Need:
Licensure / Certification / Registration:
- BLS Provider obtained within 1 Month (30 days) of hire date or job transfer date required. American Heart Association or American Red Cross accepted.
- Nurse Practitioner specializing in Prescriptive Authority credentialed from the Indiana Board of Nursing obtained within 6 Months (180 days) of hire date or job transfer date required.
- One or more of the following required:
+ Nurse Practitioner credentialed from the Indiana Board of Nursing obtained within 6 Months (180 days) of hire date or job transfer date. Valid state license required specific to the state in which the associate works.
+ Nurse Practitioner credentialed from the American Nurses Credentialing Center (ANCC) obtained within 6 Months (180 days) of hire date or job transfer date. Valid state license required specific to the state in which the associate works.
+ Nurse Practitioner credentialed from the National Certification Corporation (NCC) obtained within 6 Months (180 days) of hire date or job transfer date. Valid state license required specific to the state in which the associate works.
+ Registered Nurse credentialed from the American Nurses Credentialing Center (ANCC) obtained prior to hire date or job transfer date.
+ Registered Nurse credentialed from the Indiana Board of Nursing obtained prior to hire date or job transfer date.
Education:
Master's degree of Nursing required.
Visa Eligibility: None
Equal Employment Opportunity Employer:
Ascension provides Equal Employment Opportunities (EEO) to all associates and applicants for employment without regard to race, color, religion, sex/gender, sexual orientation, gender identity or expression, pregnancy, childbirth, and related medical conditions, lactation, breastfeeding, national origin, citizenship, age, disability, genetic information, veteran status, marital status, all as defined by applicable law, and any other legally protected status or characteristic in accordance with applicable federal, state and local laws. For further information, view the EEO Know Your Rights (English) poster or EEO Know Your Rights (Spanish) poster.
Fraud prevention notice
Prospective applicants should be vigilant against fraudulent job offers and interview requests. Scammers may use sophisticated tactics to impersonate Ascension employees. To ensure your safety, please remember: Ascension will never ask for payment or to provide banking or financial information as part of the job application or hiring process. Our legitimate email communications will always come from an @ascension.org email address; do not trust other domains, and an official offer will only be extended to candidates who have completed a job application through our authorized applicant tracking system.
E-Verify statement
Employer participates in the Electronic Employment Verification Program. Please click here for more information.
Why Join Our Team?:
Ascension is a leading nonprofit Catholic health system with a culture and associate experience grounded in service, growth, care and connection. We empower our 97,000+ associates to bring their skills and expertise every day to reimagining healthcare, together. Recognized as one of the Best 150+ Places to Work in Healthcare and a Military-Friendly Gold Employer, you’ll find an inclusive and supportive environment where your contributions truly matter.
Benefits:
- Paid time off (PTO)
- Various health insurance options & wellness plans
- Retirement benefits including employer match plans
- Long-term & short-term disability
- Employee assistance programs (EAP)
- Parental leave & adoption assistance
- Tuition reimbursement
- Ways to give back to your community
Benefit options and eligibility vary by position. Compensation varies based on factors including, but not limited to, experience, skills, education, performance, location and salary range at the time of the offer.
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Find JobsInternal Medicine Nurse Practitioner Job Market
A snapshot from current openings nationwide, updated as new roles post.
Who's Hiring
- Ascension4

- Texas Health Resources2

- Beth Israel Lahey Health1

- Bronson Healthcare1

- CareMed Primary and Urgent Care1

Top Industries Hiring
- Healthcare & Medical Services15
- Non-Profit & Social Services2
What Employers Look For
The qualifications that appear most often in internal medicine nurse practitioner jobs.
- Active APRN license with adult or family nurse practitioner board certification (ANCC or AANP)
- Master of Science in Nursing or Doctor of Nursing Practice degree from an accredited program
- DEA registration and state prescriptive authority for controlled substances
- Minimum one to three years of clinical experience in internal medicine or primary care
- Proficiency with electronic health record systems such as Epic, Cerner, or Meditech
- Basic Life Support and Advanced Cardiovascular Life Support certification
Tips for Your Internal Medicine Nurse Practitioner Job Search
Tailor your resume to inpatient versus outpatient
Internal medicine NP roles split sharply between inpatient hospital medicine and outpatient clinic settings. Lead your resume with the setting you're targeting and highlight matching experience first, because hiring managers screen for this before anything else.
List every chronic disease condition you manage
Employers filter for specific conditions like hypertension, diabetes, COPD, and heart failure. Name each condition you manage independently in your resume's clinical experience section rather than grouping them under a vague phrase like 'chronic disease management.'
Apply early to roles that fit
Migrate Mate lists internal medicine nurse practitioner openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Filter openings by your NP licensure compact status
If you hold a compact license through the Nurse Licensure Compact, you're eligible in all member states without additional licensure. Target openings in those states specifically, and note your compact status prominently in your application materials.
Prepare a clinical case walkthrough for interviews
Most internal medicine NP interviews include a clinical scenario where you talk through your diagnostic reasoning and management plan. Prepare two or three cases involving complex comorbidities you've handled independently, and practice explaining your decision-making out loud.
Negotiate your collaborative practice agreement terms
In states requiring physician oversight, ask about the collaborative agreement structure during the offer stage, including how accessible your collaborating physician is and whether the agreement covers your full scope of practice. This affects your day-to-day autonomy more than your title does.
Internal Medicine Nurse Practitioner Jobs: Frequently Asked Questions
Which companies are hiring the most internal medicine nurse practitioners?
The companies hiring the most internal medicine nurse practitioners right now include Ascension, Texas Health Resources, and Beth Israel Lahey Health, with the largest share of openings in Massachusetts, New York, and Texas, based on current listings on Migrate Mate as of June 2026. Demand is concentrated in health systems with large outpatient internal medicine departments and multi-specialty group practices.
How many internal medicine nurse practitioner jobs are remote?
About 0% of internal medicine nurse practitioner openings are fully remote or hybrid as of June 2026, with most remote opportunities concentrated in telehealth chronic disease management, post-acute follow-up care, and care coordination roles rather than direct primary care clinical positions.
How do you become an internal medicine nurse practitioner?
You start by earning a registered nurse license, then complete an accredited master's or doctoral NP program with an adult-gerontology or family NP track. After graduating, you sit for board certification through ANCC or AANP, obtain your state APRN license, secure DEA registration, and gain clinical hours in an internal medicine or general medicine setting.
Can you get hired as an internal medicine nurse practitioner with little experience?
Yes, some health systems hire new-grad NPs into internal medicine residency or fellowship programs that provide supervised clinical training before independent practice. Outpatient group practices are more likely to hire early-career NPs than hospital medicine units. Completing clinical rotations specifically in internal medicine and earning strong preceptor references significantly improves your chances.
What does the internal medicine nurse practitioner interview process look like?
Most hiring processes include an initial phone screen with HR, followed by a clinical interview with the medical director or lead physician that covers your diagnostic approach and scope of practice. You may then meet with the broader clinical team and complete a panel interview. Some employers add a written clinical scenario or EMR demonstration before extending an offer.
Where can I find and apply to internal medicine nurse practitioner jobs?
You can find and apply to internal medicine nurse practitioner jobs on Migrate Mate, which lists current openings from across the United States. Search the listings to find roles that match your clinical background, setting preference, and location, then apply directly to each opening that fits.
See All Internal Medicine Nurse Practitioner Jobs
Jump back to the full list of openings and apply to any internal medicine nurse practitioner role that fits.
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