Internal Medicine Nurse Practitioner Jobs

Internal Medicine Nurse Practitioner jobs are open across hospital systems, outpatient clinics, academic medical centers, and multi-specialty practices, from new-grad NP to experienced lead roles, with specializations in chronic disease management, primary care, and hospital medicine. Find a role that fits from the openings below and apply directly.

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Overview

Open roles20+
Top stateMassachusetts
Top employerAscension
Top cityDallas, TX
Work type100% On-site
Top industryHealthcare

Showing 5 of 20+ Internal Medicine Nurse Practitioner jobs

Ascension
Internal Medicine NP / PA
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Ascension
Added 1w ago
Internal Medicine NP / PA
Ascension
Indianapolis, Indiana
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Master's
10,000+

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Ascension
Internal Medicine NP / PA
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Ascension
Added 2w ago
Internal Medicine NP / PA
Ascension
Carmel, Indiana
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Doctorate
10,000+

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Ascension
Internal Medicine NP / PA
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Ascension
Added 2w ago
Internal Medicine NP / PA
Ascension
Inlet Beach, Florida
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Master's
10,000+

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Ascension
Internal Medicine NP / PA
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Ascension
Added 1mo ago
Internal Medicine NP / PA
Ascension
Miramar Beach, Florida
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Master's
10,000+

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CareMed Primary and Urgent Care
Family/Internal Medicine NP
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CareMed Primary and Urgent Care
Added 1mo ago
Family/Internal Medicine NP
CareMed Primary and Urgent Care
Patchogue, New York
Nursing
Healthcare Administration
Patient Services & Wellbeing
$145k - $160k/yr
On-Site
None

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Internal Medicine Nurse Practitioner Job Market

A snapshot from current openings nationwide, updated as new roles post.

Who's Hiring

  • Ascension
    Ascension4
  • Texas Health Resources
    Texas Health Resources2
  • Beth Israel Lahey Health
    Beth Israel Lahey Health1
  • Bronson Healthcare
    Bronson Healthcare1
  • CareMed Primary and Urgent Care
    CareMed Primary and Urgent Care1

Top Industries Hiring

  • Healthcare & Medical Services15
  • Non-Profit & Social Services2

What Employers Look For

The qualifications that appear most often in internal medicine nurse practitioner jobs.

  • Active APRN license with adult or family nurse practitioner board certification (ANCC or AANP)
  • Master of Science in Nursing or Doctor of Nursing Practice degree from an accredited program
  • DEA registration and state prescriptive authority for controlled substances
  • Minimum one to three years of clinical experience in internal medicine or primary care
  • Proficiency with electronic health record systems such as Epic, Cerner, or Meditech
  • Basic Life Support and Advanced Cardiovascular Life Support certification

Tips for Your Internal Medicine Nurse Practitioner Job Search

Tailor your resume to inpatient versus outpatient

Internal medicine NP roles split sharply between inpatient hospital medicine and outpatient clinic settings. Lead your resume with the setting you're targeting and highlight matching experience first, because hiring managers screen for this before anything else.

List every chronic disease condition you manage

Employers filter for specific conditions like hypertension, diabetes, COPD, and heart failure. Name each condition you manage independently in your resume's clinical experience section rather than grouping them under a vague phrase like 'chronic disease management.'

Apply early to roles that fit

Migrate Mate lists internal medicine nurse practitioner openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Filter openings by your NP licensure compact status

If you hold a compact license through the Nurse Licensure Compact, you're eligible in all member states without additional licensure. Target openings in those states specifically, and note your compact status prominently in your application materials.

Prepare a clinical case walkthrough for interviews

Most internal medicine NP interviews include a clinical scenario where you talk through your diagnostic reasoning and management plan. Prepare two or three cases involving complex comorbidities you've handled independently, and practice explaining your decision-making out loud.

Negotiate your collaborative practice agreement terms

In states requiring physician oversight, ask about the collaborative agreement structure during the offer stage, including how accessible your collaborating physician is and whether the agreement covers your full scope of practice. This affects your day-to-day autonomy more than your title does.

Internal Medicine Nurse Practitioner Jobs: Frequently Asked Questions

Which companies are hiring the most internal medicine nurse practitioners?

The companies hiring the most internal medicine nurse practitioners right now include Ascension, Texas Health Resources, and Beth Israel Lahey Health, with the largest share of openings in Massachusetts, New York, and Texas, based on current listings on Migrate Mate as of June 2026. Demand is concentrated in health systems with large outpatient internal medicine departments and multi-specialty group practices.

How many internal medicine nurse practitioner jobs are remote?

About 0% of internal medicine nurse practitioner openings are fully remote or hybrid as of June 2026, with most remote opportunities concentrated in telehealth chronic disease management, post-acute follow-up care, and care coordination roles rather than direct primary care clinical positions.

How do you become an internal medicine nurse practitioner?

You start by earning a registered nurse license, then complete an accredited master's or doctoral NP program with an adult-gerontology or family NP track. After graduating, you sit for board certification through ANCC or AANP, obtain your state APRN license, secure DEA registration, and gain clinical hours in an internal medicine or general medicine setting.

Can you get hired as an internal medicine nurse practitioner with little experience?

Yes, some health systems hire new-grad NPs into internal medicine residency or fellowship programs that provide supervised clinical training before independent practice. Outpatient group practices are more likely to hire early-career NPs than hospital medicine units. Completing clinical rotations specifically in internal medicine and earning strong preceptor references significantly improves your chances.

What does the internal medicine nurse practitioner interview process look like?

Most hiring processes include an initial phone screen with HR, followed by a clinical interview with the medical director or lead physician that covers your diagnostic approach and scope of practice. You may then meet with the broader clinical team and complete a panel interview. Some employers add a written clinical scenario or EMR demonstration before extending an offer.

Where can I find and apply to internal medicine nurse practitioner jobs?

You can find and apply to internal medicine nurse practitioner jobs on Migrate Mate, which lists current openings from across the United States. Search the listings to find roles that match your clinical background, setting preference, and location, then apply directly to each opening that fits.

See All Internal Medicine Nurse Practitioner Jobs

Jump back to the full list of openings and apply to any internal medicine nurse practitioner role that fits.

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