RN Staff Nurse Jobs in Missouri
RN Staff Nurse jobs in Missouri are concentrated in Kansas City, St. Louis, and Springfield, where major health systems including BJC HealthCare, Saint Luke's Health System, and Mercy Health maintain large hospital campuses and steady hiring pipelines. Demand runs from new graduate through experienced charge nurse, with the most consistent openings in med-surg, critical care, and emergency nursing across both urban academic medical centers and regional community hospitals. Missouri participates in the Nurse Licensure Compact, so nurses holding a multistate license from another compact state can work here without an additional application. Scan the live roles below and apply to whichever ones fit.
Find RN Staff Nurse JobsOverview
Showing 5 of 15+ RN Staff Nurse jobs
Location
ST. LOUIS, MO 63141Scheduled Hours
40Position Summary
Don’t miss the opportunity to join our team with WashU Department of Urologic Surgery!We have approximately 14 providers who see patients at this location. We have 3-6 providers in the office each day. Our staff is comprised of RNs, LPNs and MAs. We are a close group that works as one team regardless of job title.
Our providers typically see 16-24 patients per day. We see adults of all ages. Our population consists of patients who are surgical and/or procedural with a condition that is urological in nature. The RN role is multifaceted with a heavy emphasis on in-office procedures. This role also includes assisting providers with patient care, pre-op education, and diagnostic testing.
Our clinical team rotates positions each day, some days working with a provider, some days seeing patients. This job is fully clinical. There is no back-office work involved. No calling patients, no pre-certs, no scheduling, etc.
This position is Monday- Friday, 7:30 am - 4:00 pm, no weekends or holidays!
Position provides direct patient care and education for patients receiving treatments, examinations, surgeries, etc., in a medical office according to established procedures.
Job Description
Primary Duties & Responsibilities:
- Utilizes the nursing process in assessing, planning, implementing and evaluating a plan of patient care.
- Provides patient care, which may include administering medication, performing procedures and monitoring patient status in accordance with approved nursing practice.
- Provides appropriate counsel and education to patients/families regarding disease process and symptom management.
- Maintains medical records requiring appropriate and timely recording of patient information.
- Consults with members of the health care team, adjusting nursing care processes as indicated to ensure optimal patient outcomes.
- Assists the health care provider with examinations, procedures, prescription refills and other processes related to direct patient care.
- Maintains required skills and competencies and participates in educational programs, staff meetings and in services such as CPR as required. Performs other duties as assigned.
Working Conditions:
Job Location/Working Conditions
- Normal office environment
- Exposure to blood-borne pathogens
- Requires protective devices
- Patient care setting Direct patient care setting
Physical Effort
- Typically sitting at desk or table
- Repetitive wrist, hand or finger movement Occasional lifting (25 lbs. or less)
Equipment
- Office equipment
- Clinical/diagnostic equipment
Required Qualifications
Education:
Associate degree - Nursing
Certifications /Professional Licenses :
Work Experience:
Skills:
Driver's License:
More About This Job
Required Qualifications:
- Graduate of an accredited nursing program.
- Current RN licensure in the state of Missouri and/or Illinois, depending on location, in accordance with Compact Act.
- Basic Life Support certification (Online BLS certifications, those without a skills assessment component, are not sufficient to meet the BLS requirements).
Preferred Qualifications
Education:
No additional education unless stated elsewhere in the job posting.
Certifications /Professional Licenses :
Work Experience:
Skills:
Active Listening, Adaptability, Customer Empathy, Detail-Oriented, Effective Written Communication, Electronic Health Records (EHR), Emergency Situations, Epic EHR, General Nursing, Handling Crisis Situations, Medication Administration, Nursing Practice, Oral Communications, Patient Charting, Patient Education, Prioritization, Team Collaboration, Vital SignsGrade
S25Salary Range
$60,000.00 - $99,900.00 / Annually The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ .
Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.Benefits Statement
Personal
Up to 22 days of vacation, 10 recognized holidays, and sick time.
Competitive health insurance packages with priority appointments and lower copays/coinsurance.
Take advantage of our free Metro transit U-Pass for eligible employees.
WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.Location
ST. LOUIS, MO 63141Scheduled Hours
40Position Summary
Don’t miss the opportunity to join our team with WashU Department of Urologic Surgery!We have approximately 14 providers who see patients at this location. We have 3-6 providers in the office each day. Our staff is comprised of RNs, LPNs and MAs. We are a close group that works as one team regardless of job title.
Our providers typically see 16-24 patients per day. We see adults of all ages. Our population consists of patients who are surgical and/or procedural with a condition that is urological in nature. The RN role is multifaceted with a heavy emphasis on in-office procedures. This role also includes assisting providers with patient care, pre-op education, and diagnostic testing.
Our clinical team rotates positions each day, some days working with a provider, some days seeing patients. This job is fully clinical. There is no back-office work involved. No calling patients, no pre-certs, no scheduling, etc.
This position is Monday- Friday, 7:30 am - 4:00 pm, no weekends or holidays!
Position provides direct patient care and education for patients receiving treatments, examinations, surgeries, etc., in a medical office according to established procedures.
Job Description
Primary Duties & Responsibilities:
- Utilizes the nursing process in assessing, planning, implementing and evaluating a plan of patient care.
- Provides patient care, which may include administering medication, performing procedures and monitoring patient status in accordance with approved nursing practice.
- Provides appropriate counsel and education to patients/families regarding disease process and symptom management.
- Maintains medical records requiring appropriate and timely recording of patient information.
- Consults with members of the health care team, adjusting nursing care processes as indicated to ensure optimal patient outcomes.
- Assists the health care provider with examinations, procedures, prescription refills and other processes related to direct patient care.
- Maintains required skills and competencies and participates in educational programs, staff meetings and in services such as CPR as required. Performs other duties as assigned.
Working Conditions:
Job Location/Working Conditions
- Normal office environment
- Exposure to blood-borne pathogens
- Requires protective devices
- Patient care setting Direct patient care setting
Physical Effort
- Typically sitting at desk or table
- Repetitive wrist, hand or finger movement Occasional lifting (25 lbs. or less)
Equipment
- Office equipment
- Clinical/diagnostic equipment
Required Qualifications
Education:
Associate degree - Nursing
Certifications /Professional Licenses :
Work Experience:
Skills:
Driver's License:
More About This Job
Required Qualifications:
- Graduate of an accredited nursing program.
- Current RN licensure in the state of Missouri and/or Illinois, depending on location, in accordance with Compact Act.
- Basic Life Support certification (Online BLS certifications, those without a skills assessment component, are not sufficient to meet the BLS requirements).
Preferred Qualifications
Education:
No additional education unless stated elsewhere in the job posting.
Certifications /Professional Licenses :
Work Experience:
Skills:
Active Listening, Adaptability, Customer Empathy, Detail-Oriented, Effective Written Communication, Electronic Health Records (EHR), Emergency Situations, Epic EHR, General Nursing, Handling Crisis Situations, Medication Administration, Nursing Practice, Oral Communications, Patient Charting, Patient Education, Prioritization, Team Collaboration, Vital SignsGrade
S25Salary Range
$60,000.00 - $99,900.00 / Annually The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ .
Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.Benefits Statement
Personal
Up to 22 days of vacation, 10 recognized holidays, and sick time.
Competitive health insurance packages with priority appointments and lower copays/coinsurance.
Take advantage of our free Metro transit U-Pass for eligible employees.
WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.See All 15 RN Staff Nurse Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find RN Staff Nurse JobsRN Staff Nurse Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
RN Staff Nurse Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- Washington University in St. Louis13
- US Department of Veterans Affairs1
- Mid-America Gastrointestinal Consultants1
Top Industries Hiring
- Education
What Missouri Employers Look For
The qualifications that appear most often in RN staff nurse jobs across Missouri.
- Active Missouri RN license or multistate Nurse Licensure Compact license recognized in Missouri
- Associate or bachelor's degree in nursing from an accredited program
- Current BLS certification required before start date
- Minimum one year of acute care or clinical nursing experience preferred
- ACLS or PALS certification required for critical care, emergency, and specialty units
- Ability to work rotating shifts including nights, weekends, and holidays as scheduled
RN Staff Nurse Jobs in Missouri: Frequently Asked Questions
How do you become a rn staff nurse in Missouri?
You become an rn staff nurse in Missouri by completing an accredited associate or bachelor's degree nursing program, passing the NCLEX-RN examination, and obtaining licensure through the Missouri State Board of Nursing. Missouri is a Nurse Licensure Compact member, so nurses already holding a multistate license from another compact state may practice in Missouri without applying for a separate state license, though single-state Missouri license holders still apply through the Board directly.
How much do RN staff nurses make in Missouri?
RN staff nurses in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire rn staff nurses in Missouri?
Companies currently hiring rn staff nurses in Missouri include Washington University in St. Louis, US Department of Veterans Affairs, and Mid-America Gastrointestinal Consultants, per current listings on Migrate Mate as of August 2026. Missouri's largest health systems, including BJC HealthCare, Mercy Health, and Saint Luke's, consistently post staff nurse openings across multiple hospital campuses and specialty service lines throughout the state.
Which Missouri cities have the most rn staff nurse jobs?
St. Louis, Columbia, and Creve Coeur account for the most rn staff nurse openings in Missouri. St. Louis leads because of its concentration of academic medical centers and large regional health systems, Kansas City follows with major multisite employers across both sides of the state line, and Springfield anchors the southwest corridor where Mercy and Cox Health operate flagship campuses serving a broad rural catchment area.
Are there remote rn staff nurse jobs in Missouri?
Yes, but they're rare. Bedside nursing is fundamentally hands-on, so the large majority of rn staff nurse roles require on-site presence in a hospital or clinical setting. About 20% of rn staff nurse openings tied to Missouri are remote or hybrid as of August 2026, and those positions are almost exclusively in telephonic triage, utilization review, or case management functions rather than direct patient care.
How can I get hired as a rn staff nurse in Missouri with little or no experience?
The most realistic entry path is a new-graduate nurse residency program, and Missouri's largest systems run structured ones, including BJC HealthCare's New Graduate Nurse Residency and Mercy Health's transition-to-practice program, which are designed specifically for nurses with no post-graduation experience. Candidates who complete clinical rotations at the hiring facility or who move laterally from licensed practical nurse or patient care technician roles tend to compete well. Holding an active Missouri RN license or multistate compact license before applying, and targeting med-surg or telemetry units as the most accessible entry points, gives candidates the clearest advantage.
Where can I find and apply to rn staff nurse jobs in Missouri?
You can find and apply to rn staff nurse jobs in Missouri on Migrate Mate, which lists current Missouri openings updated in real time. Search the available roles, identify the ones that match your experience, specialty, and preferred location within Missouri, and apply directly to each position that fits.
See All 15 RN Staff Nurse Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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