Emergency Department Registered Nurse Jobs in Missouri
Emergency Department Registered Nurse jobs in Missouri are concentrated in the state's major health systems, trauma centers, and regional hospital networks, with consistent demand from entry-level to charge and clinical lead positions. The largest hiring markets are Kansas City, St. Louis, and Springfield, where established systems like BJC HealthCare, Saint Luke's Health System, and CoxHealth maintain busy emergency departments year-round. Pediatric emergency care, trauma nursing, and critical care triage are among the most in-demand specialties across Missouri facilities. Find a role that fits below and apply directly.
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MO-SSM Health DePaul Hospital - St. LouisWorker Type:
RegularJob Summary:
Provides leadership and coordination of unit staffing while ensuring implementation of clinical objectives and quality patient care.Job Responsibilities and Requirements:
PRIMARY RESPONSIBILITIES
- Assigns, directs, educates and monitors nursing and support staff during assigned shift. Contributes to or performs performance evaluations of staff.
- Assesses daily patient care needs and develops and distributes patient care assignments, ensuring that population appropriate patient care is given.
- Collaborates with advanced practice providers to ensure quality outcomes.
- Evaluates the effectiveness of patient care and identifies any issues that affect desired patient outcomes.
- Responds to complaints about patient care and manages through established channels.
- May provide input for hiring, training, directing, developing and evaluating staff.
- Works in a constant state of alertness and safe manner.
- Performs other duties as assigned.
EDUCATION
- Graduate of accredited school of nursing or education equivalency for licensing
EXPERIENCE
- One year of registered nurse experience
PHYSICAL REQUIREMENTS
- Constant use of speech to share information through oral communication.
- Constant standing and walking.
- Frequent lifting/carrying and pushing/pulling objects weighing 0-25 lbs.
- Frequent sitting, reaching and keyboard use/data entry.
- Frequent use of vision and depth perception for distances near (20 inches or less) and far (20 feet or more) and to identify and distinguish colors.
- Frequent use of smell to detect/recognize odors.
- Frequent use of hearing to receive oral communication, distinguish body sounds and/or hear alarms, malfunctioning machinery, etc.
- Occasional lifting/carrying and pushing/pulling objects weighing 25-50 lbs.
- Occasional lifting/moving of patients.
- Occasional bending, stooping, kneeling, squatting, twisting, gripping and repetitive foot/leg and hand/arm movements.
- Occasional driving.
- Rare crawling and running.
REQUIRED PROFESSIONAL LICENSE AND/OR CERTIFICATIONS
State of Work Location: Illinois
- Basic Life Support HealthCare Provider (BLS HCP) - American Heart Association (AHA)
- And
- Registered Professional Nurse (RN) - Illinois Department of Financial and Professional Regulation (IDFPR)
- And
- Advanced Life Support (ALS) - American Heart Association (AHA)
- Or
- Emergency Nursing Pediatric Course (ENPC) - Emergency Nurses Association (ENA)
- Or
- Neonatal Resuscitation Program (NRP) - American Academy Pediatrics (AAP)
- Or
- Pediatric Advanced Life Support (PALS) - American Heart Association (AHA)
- Or
- Trauma Nursing Core Course (TNCC) - Emergency Nurses Association (ENA)
- Or
- Neonatal Resuscitation Program (NRP) Essentials - American Academy of Pediatrics (AAP)
State of Work Location: Missouri
- Basic Life Support HealthCare Provider (BLS HCP) - American Heart Association (AHA)
- And
- Registered Nurse (RN) - Missouri Division of Professional Registration
- Or
- Registered Nurse (RN) Issued by Compact State
- And
- Advanced Life Support (ALS) - American Heart Association (AHA)
- Or
- Emergency Nursing Pediatric Course (ENPC) - Emergency Nurses Association (ENA)
- Or
- Neonatal Resuscitation Program (NRP) - American Academy Pediatrics (AAP)
- Or
- Pediatric Advanced Life Support (PALS) - American Heart Association (AHA)
- Or
- Trauma Nursing Core Course (TNCC) - Emergency Nurses Association (ENA)
- Or
- Neonatal Resuscitation Program (NRP) Essentials - American Academy of Pediatrics (AAP)
State of Work Location: Oklahoma
- Basic Life Support HealthCare Provider (BLS HCP) - American Heart Association (AHA)
- And
- Registered Nurse (RN) Issued by Compact State
- And
- Registered Nurse (RN) - Oklahoma Board of Nursing (OBN)
- And
- Advanced Life Support (ALS) - American Heart Association (AHA)
- Or
- Emergency Nursing Pediatric Course (ENPC) - Emergency Nurses Association (ENA)
- Or
- Neonatal Resuscitation Program (NRP) - American Academy Pediatrics (AAP)
- Or
- Pediatric Advanced Life Support (PALS) - American Heart Association (AHA)
- Or
- Trauma Nursing Core Course (TNCC) - Emergency Nurses Association (ENA)
- Or
- Neonatal Resuscitation Program (NRP) Essentials - American Academy of Pediatrics (AAP)
State of Work Location: Wisconsin
- Basic Life Support HealthCare Provider (BLS HCP) - American Heart Association (AHA)
- And
- Registered Nurse (RN) Issued by Compact State
- Or
- Registered Nurse (RN) - Wisconsin Department of Safety and Professional Services
- And
- Advanced Life Support (ALS) - American Heart Association (AHA)
- Or
- Emergency Nursing Pediatric Course (ENPC) - Emergency Nurses Association (ENA)
- Or
- Neonatal Resuscitation Program (NRP) - American Academy Pediatrics (AAP)
- Or
- Pediatric Advanced Life Support (PALS) - American Heart Association (AHA)
- Or
- Trauma Nursing Core Course (TNCC) - Emergency Nurses Association (ENA)
- Or
- Neonatal Resuscitation Program (NRP) Essentials - American Academy of Pediatrics (AAP)
Work Shift:
Night Shift (United States of America)Job Type:
Department:
2000000128 Emergency DeptScheduled Weekly Hours:
36Benefits:
SSM Health values our exceptional employees by offering a comprehensive benefits package to fit their needs.
Paid Parental Leave: we offer eligible team members one week of paid parental leave for newborns or newly adopted children (pro-rated based on FTE).
Flexible Payment Options: our voluntary benefit offered through DailyPay offers eligible hourly team members instant access to their earned, unpaid base pay (fees may apply) before payday.
Upfront Tuition Coverage: we provide upfront tuition coverage through FlexPath Funded for eligible team members.
See All 58 Emergency Department Registered Nurse Jobs in Missouri
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Find JobsEmergency Department Registered Nurse Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Emergency Department Registered Nurse Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What Missouri Employers Look For
The qualifications that appear most often in emergency department registered nurse jobs across Missouri.
- Active registered nurse license issued or recognized by the Missouri State Board of Nursing
- Current BLS certification required, with ACLS and TNCC strongly preferred by most employers
- Minimum one to two years of emergency department or acute care clinical experience
- Ability to triage patients and manage a high-volume, fast-paced emergency environment
- Proficiency with electronic health record systems, commonly Epic or Cerner in Missouri facilities
- Strong communication skills for coordinating with physicians, specialists, and interdisciplinary teams
Emergency Department Registered Nurse Jobs in Missouri: Frequently Asked Questions
How do you become a emergency department registered nurse in Missouri?
You become an emergency department registered nurse in Missouri by earning an associate or bachelor's degree in nursing, passing the NCLEX-RN, and obtaining licensure from the Missouri State Board of Nursing. Missouri participates in the Nurse Licensure Compact, so nurses licensed in other compact states can often practice without a separate Missouri license. Most emergency department positions additionally expect BLS certification and, for higher-acuity roles, ACLS or trauma nursing credentials.
How much do emergency department registered nurses make in Missouri?
Emergency department registered nurses in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire emergency department registered nurses in Missouri?
Companies currently hiring emergency department registered nurses in Missouri include Mercy, BJC HealthCare, and SSM Health, per current listings on Migrate Mate as of August 2026. Missouri's largest health systems, including those anchored in the Kansas City and St. Louis metro areas, account for the bulk of ongoing emergency nursing openings across the state.
Which Missouri cities have the most emergency department registered nurse jobs?
St. Louis, Kansas City, and Joplin are the Missouri cities with the most emergency department registered nurse openings. St. Louis and Kansas City drive the majority of postings because they are home to the state's largest academic medical centers and Level I trauma facilities, while Springfield's concentration of regional hospital systems, led by CoxHealth and Mercy, sustains steady demand in southwest Missouri.
Are there remote emergency department registered nurse jobs in Missouri?
Yes, but they're rare. Emergency department nursing is a hands-on clinical role that requires physical presence at the bedside, so on-site positions make up the overwhelming majority of openings. About 0% of emergency department registered nurse openings tied to Missouri are remote or hybrid as of August 2026, and those roles are almost exclusively in tele-triage, utilization review, or case management rather than direct patient care.
How can I get hired as a emergency department registered nurse in Missouri with little or no experience?
The most realistic entry path is applying to a nurse residency or new-graduate transition program, which BJC HealthCare, Saint Luke's Health System, and CoxHealth all run for newly licensed RNs. These structured programs rotate new graduates through the emergency department with dedicated preceptors before independent practice. Candidates without ED experience who hold an active Missouri RN license and BLS certification and have backgrounds in medical-surgical, ICU, or paramedic roles are also competitive for junior ED positions at Missouri community hospitals.
Where can I find and apply to emergency department registered nurse jobs in Missouri?
You can find and apply to emergency department registered nurse jobs in Missouri on Migrate Mate, which lists current Missouri openings from health systems and hospitals across the state. Find the roles that fit your experience and credentials and apply directly to the ones that match.
See All 58 Emergency Department Registered Nurse Jobs in Missouri
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