Emergency Department Registered Nurse Jobs in Missouri

Emergency Department Registered Nurse jobs in Missouri are concentrated in the state's major health systems, trauma centers, and regional hospital networks, with consistent demand from entry-level to charge and clinical lead positions. The largest hiring markets are Kansas City, St. Louis, and Springfield, where established systems like BJC HealthCare, Saint Luke's Health System, and CoxHealth maintain busy emergency departments year-round. Pediatric emergency care, trauma nursing, and critical care triage are among the most in-demand specialties across Missouri facilities. Find a role that fits below and apply directly.

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Overview

Open roles58
Top employerMercy
Top citySt. Louis, MO
Cities hiring27
Work type100% On-site
Top industryHealthcare

Showing 5 of 58+ Emergency Department Registered Nurse jobs

SSM Health
Charge Registered Nurse - Emergency Department
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SSM Health
Added 1d ago
Charge Registered Nurse - Emergency Department
SSM Health
Bridgeton, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
Managed Registered Nurses (RNs)
10,000+

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SSM Health
Registered Nurse - Emergency Department
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SSM Health
Added 1d ago
Registered Nurse - Emergency Department
SSM Health
Bridgeton, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
TNCC Certification
10,000+

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Mercy
RN Emergency Department (Nights)
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Mercy
Added 1d ago
RN Emergency Department (Nights)
Mercy
Joplin, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
BLS Certification
10,000+

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BJC HealthCare
Clinical Nurse Emergency Department
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BJC HealthCare
Added 1d ago
Clinical Nurse Emergency Department
BJC HealthCare
St. Louis, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
$32 - $48.28/hr
Bachelor of Science
10,000+

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H
Emergency Department RN-PRN
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H
Added 1d ago
Emergency Department RN-PRN
Harrison County Community Hospital District
Bethany, Missouri
Customer Service
Customer Support
Hospitality & Guest Services
TNCC Certification

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See All 58 Emergency Department Registered Nurse Jobs in Missouri

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Emergency Department Registered Nurse Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
11 jobs
Kansas City
6 jobs
Joplin
3 jobs
Bethany
3 jobs
Columbia
3 jobs
Bridgeton
3 jobs
Bolivar
2 jobs
Liberty
2 jobs
Florissant
2 jobs

Emergency Department Registered Nurse Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

Mercy
Mercy9 open roles
BJC HealthCare
BJC HealthCare9 open roles
SSM Health
SSM Health5 open roles

Top Industries Hiring

  • Healthcare & Medical Services

What Missouri Employers Look For

The qualifications that appear most often in emergency department registered nurse jobs across Missouri.

  • Active registered nurse license issued or recognized by the Missouri State Board of Nursing
  • Current BLS certification required, with ACLS and TNCC strongly preferred by most employers
  • Minimum one to two years of emergency department or acute care clinical experience
  • Ability to triage patients and manage a high-volume, fast-paced emergency environment
  • Proficiency with electronic health record systems, commonly Epic or Cerner in Missouri facilities
  • Strong communication skills for coordinating with physicians, specialists, and interdisciplinary teams

Emergency Department Registered Nurse Jobs in Missouri: Frequently Asked Questions

How do you become a emergency department registered nurse in Missouri?

You become an emergency department registered nurse in Missouri by earning an associate or bachelor's degree in nursing, passing the NCLEX-RN, and obtaining licensure from the Missouri State Board of Nursing. Missouri participates in the Nurse Licensure Compact, so nurses licensed in other compact states can often practice without a separate Missouri license. Most emergency department positions additionally expect BLS certification and, for higher-acuity roles, ACLS or trauma nursing credentials.

How much do emergency department registered nurses make in Missouri?

Emergency department registered nurses in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire emergency department registered nurses in Missouri?

Companies currently hiring emergency department registered nurses in Missouri include Mercy, BJC HealthCare, and SSM Health, per current listings on Migrate Mate as of August 2026. Missouri's largest health systems, including those anchored in the Kansas City and St. Louis metro areas, account for the bulk of ongoing emergency nursing openings across the state.

Which Missouri cities have the most emergency department registered nurse jobs?

St. Louis, Kansas City, and Joplin are the Missouri cities with the most emergency department registered nurse openings. St. Louis and Kansas City drive the majority of postings because they are home to the state's largest academic medical centers and Level I trauma facilities, while Springfield's concentration of regional hospital systems, led by CoxHealth and Mercy, sustains steady demand in southwest Missouri.

Are there remote emergency department registered nurse jobs in Missouri?

Yes, but they're rare. Emergency department nursing is a hands-on clinical role that requires physical presence at the bedside, so on-site positions make up the overwhelming majority of openings. About 0% of emergency department registered nurse openings tied to Missouri are remote or hybrid as of August 2026, and those roles are almost exclusively in tele-triage, utilization review, or case management rather than direct patient care.

How can I get hired as a emergency department registered nurse in Missouri with little or no experience?

The most realistic entry path is applying to a nurse residency or new-graduate transition program, which BJC HealthCare, Saint Luke's Health System, and CoxHealth all run for newly licensed RNs. These structured programs rotate new graduates through the emergency department with dedicated preceptors before independent practice. Candidates without ED experience who hold an active Missouri RN license and BLS certification and have backgrounds in medical-surgical, ICU, or paramedic roles are also competitive for junior ED positions at Missouri community hospitals.

Where can I find and apply to emergency department registered nurse jobs in Missouri?

You can find and apply to emergency department registered nurse jobs in Missouri on Migrate Mate, which lists current Missouri openings from health systems and hospitals across the state. Find the roles that fit your experience and credentials and apply directly to the ones that match.

See All 58 Emergency Department Registered Nurse Jobs in Missouri

Find roles in Missouri that match your experience and apply in just a few clicks.

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