Emergency Department Registered Nurse Jobs in Missouri

Emergency Department Registered Nurse jobs in Missouri are concentrated in the state's major health systems, trauma centers, and regional hospital networks, with consistent demand from entry-level to charge and clinical lead positions. The largest hiring markets are Kansas City, St. Louis, and Springfield, where established systems like BJC HealthCare, Saint Luke's Health System, and CoxHealth maintain busy emergency departments year-round. Pediatric emergency care, trauma nursing, and critical care triage are among the most in-demand specialties across Missouri facilities. Find a role that fits below and apply directly.

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Overview

Open roles70
Top employerBJC HealthCare
Top citySt. Louis, MO
Cities hiring29
Work type100% On-site
Top industryHealthcare

Showing 5 of 70+ Emergency Department Registered Nurse jobs

Registered Nurse - Emergency Department
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Added 3d ago
Registered Nurse - Emergency Department
SSM Health
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
10,000+

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Nurse Practitioner or Physician Assistant – Emergency Department, Mercy Hospital South
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Added 5d ago
Nurse Practitioner or Physician Assistant – Emergency Department, Mercy Hospital South
Mercy
St. Louis, Missouri
Allied Health
Clinical Support
Healthcare Administration
10,000+

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Registered Nurse- Emergency Department
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Added 1w ago
Registered Nurse- Emergency Department
Saint Luke's
Kansas City, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
10,000+

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Registered Nurse - Emergency Department, Full-Time/Nights
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Added 1w ago
Registered Nurse - Emergency Department, Full-Time/Nights
Mercy
Perryville, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Fetal Heart Monitoring Certification
10,000+

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Emergency Department Clinical Nurse - (Part-Time) Nights
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Added 1w ago
Emergency Department Clinical Nurse - (Part-Time) Nights
BJC HealthCare
St. Louis, Missouri
Clinical Support
Healthcare Administration
Human Resources
$32 - $48.28/hr
Nursing Diploma
10,000+

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See All 70 Emergency Department Registered Nurse Jobs in Missouri

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Emergency Department Registered Nurse Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
14 jobs
Kansas City
13 jobs
Independence
7 jobs
Columbia
4 jobs
Clinton
2 jobs
Liberty
2 jobs
Bridgeton
2 jobs
Florissant
2 jobs
Kirksville
2 jobs

Emergency Department Registered Nurse Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • BJC HealthCare11
  • Mercy7
  • SSM Health7
  • University Health KC6
  • HealthTrust Workforce Solutions6

Top Industries Hiring

  • Healthcare & Medical Services

What Missouri Employers Look For

The qualifications that appear most often in emergency department registered nurse jobs across Missouri.

  • Active registered nurse license issued or recognized by the Missouri State Board of Nursing
  • Current BLS certification required, with ACLS and TNCC strongly preferred by most employers
  • Minimum one to two years of emergency department or acute care clinical experience
  • Ability to triage patients and manage a high-volume, fast-paced emergency environment
  • Proficiency with electronic health record systems, commonly Epic or Cerner in Missouri facilities
  • Strong communication skills for coordinating with physicians, specialists, and interdisciplinary teams

Emergency Department Registered Nurse Jobs in Missouri: Frequently Asked Questions

How do you become a emergency department registered nurse in Missouri?

You become an emergency department registered nurse in Missouri by earning an associate or bachelor's degree in nursing, passing the NCLEX-RN, and obtaining licensure from the Missouri State Board of Nursing. Missouri participates in the Nurse Licensure Compact, so nurses licensed in other compact states can often practice without a separate Missouri license. Most emergency department positions additionally expect BLS certification and, for higher-acuity roles, ACLS or trauma nursing credentials.

How much do emergency department registered nurses make in Missouri?

Emergency department registered nurses in Missouri earn a median of about $81,780 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $63,230 for the lowest 10% to over $104,390 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire emergency department registered nurses in Missouri?

Companies currently hiring emergency department registered nurses in Missouri include BJC HealthCare, Mercy, and SSM Health, per current listings on Migrate Mate as of October 2026. Missouri's largest health systems, including those anchored in the Kansas City and St. Louis metro areas, account for the bulk of ongoing emergency nursing openings across the state.

Which Missouri cities have the most emergency department registered nurse jobs?

St. Louis, Kansas City, and Independence are the Missouri cities with the most emergency department registered nurse openings. St. Louis and Kansas City drive the majority of postings because they are home to the state's largest academic medical centers and Level I trauma facilities, while Springfield's concentration of regional hospital systems, led by CoxHealth and Mercy, sustains steady demand in southwest Missouri.

Are there remote emergency department registered nurse jobs in Missouri?

Yes, but they're rare. Emergency department nursing is a hands-on clinical role that requires physical presence at the bedside, so on-site positions make up the overwhelming majority of openings. About 0% of emergency department registered nurse openings tied to Missouri are remote or hybrid as of October 2026, and those roles are almost exclusively in tele-triage, utilization review, or case management rather than direct patient care.

How can I get hired as a emergency department registered nurse in Missouri with little or no experience?

The most realistic entry path is applying to a nurse residency or new-graduate transition program, which BJC HealthCare, Saint Luke's Health System, and CoxHealth all run for newly licensed RNs. These structured programs rotate new graduates through the emergency department with dedicated preceptors before independent practice. Candidates without ED experience who hold an active Missouri RN license and BLS certification and have backgrounds in medical-surgical, ICU, or paramedic roles are also competitive for junior ED positions at Missouri community hospitals.

Where can I find and apply to emergency department registered nurse jobs in Missouri?

You can find and apply to emergency department registered nurse jobs in Missouri on Migrate Mate, which lists current Missouri openings from health systems and hospitals across the state. Find the roles that fit your experience and credentials and apply directly to the ones that match.

See All 70 Emergency Department Registered Nurse Jobs in Missouri

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