Nurse Practitioner Or Physician Assistant Jobs in Missouri
Nurse Practitioner Or Physician Assistant jobs in Missouri concentrate heavily in primary care, urgent care, and hospital-based medicine, with strong demand in cardiology, orthopedics, and behavioral health across both large health systems and rural outreach clinics. Kansas City and St. Louis anchor the most active hiring markets, with Columbia also drawing consistent openings through its university medical infrastructure. Major employers with a lasting Missouri presence include BJC HealthCare, Saint Luke's Health System, and MU Health Care. Find a role that fits below and apply directly.
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Location
ST. LOUIS, MO 63108Scheduled Hours
40Position Summary
A Nurse Practitioner or Physician Assistant specializing in Breast Medical Oncology will join the nationally recognized oncology team at Siteman Cancer Center and WashU Medicine campus in a hybrid outpatient role that combines direct patient care with dedicated administrative time. This position provides the opportunity to practice at the top of licensure while supporting patients throughout every stage of their cancer journey.The APP provider will care for adult patients with breast cancer across the disease continuum, including early-stage, locally advanced, and metastatic disease. Working collaboratively with a medical oncologist and a multidisciplinary oncology team, the Nurse Practitioner or Physician Assistant will evaluate patients, develop and manage treatment plans, monitor treatment response and treatment-related toxicities, oversee systemic anticancer therapies, provide patient and family education, coordinate supportive care services, and guide patients through treatment, survivorship, and ongoing care.
Highlights:
- Schedule: 3 outpatient clinic days + 2 admin days (remote flexibility available per department policy).
- Location: Primary care at Siteman Cancer Center, with occasional support at other WashU/Siteman sites. Primarily supports one collaborating physician.
- Focus: Dedicated Breast Medical Oncology specialty
This role is ideal for an APP who is passionate about oncology, values meaningful patient relationships, and enjoys working within a highly collaborative medical environment.
Job Description
Primary Duties & Responsibilities:
- Provides direct patient care to include obtaining patient history, performing patient assessment via observation, interview and examination; orders, performs and interprets diagnostic studies; performs preventative health assessments, screenings, immunizations and care; provides direct treatment and management of acute and chronic disease conditions; develops and implements patient-centered plan of care in collaboration with physicians, patients, consultants, nurses, ancillary care providers and others as appropriate to the patient's condition.
- May bill for services covered by collaborative practice agreement.
- Provides counseling and education of patients and their families/caregivers concerning disease management, complication prevention, disease prevention, and quality of life improvement measures, and outcome management activities.
- Monitors/ensures accuracy of patient medical records; maintains all required reports, records, statistics, etc.
- Maintains a safe, comfortable and therapeutic environment for patients/families in accordance with established clinic/hospital standards.
- Manages health conditions via prescriptive authority or referral to other healthcare providers or community resources; may perform diagnostic or therapeutic interventions consistent with certification and state regulations.
- Champions the safety and quality of care for patients using ITB therapy and serves as an expert in the care and management of ITB pumps. Helps develop a detailed educational program for the patients and lead the quality and safety initiative for the program.
- Serves as clinical expert regarding rehabilitation nursing while demonstrating a high level of autonomy and expert skill in complex clinical nursing situations.
- Provides management services for clinical research study projects; monitors participating subjects, including medication administration and family/patient education.
- Works in accordance with established departmental policies and procedures, objectives, quality assurance programs, and safety, environmental and infection control standards.
- Regularly participates in constant quality improvement and process improvement activities centered on the goal of providing exceptional, evidence-based patient care.
- Enhances professional growth and development through educational programs, current literature, in-service meetings and workshops.
- Contributes to the advancement of the rehabilitation nursing profession as a whole through research, publications, and presentations.
- Performs other duties as assigned.
Working Conditions:
Job Location/Working Conditions
Normal office environment
Exposure to blood-borne pathogens
Exposure to chemicals
Requires protective devices
Dust, dirt, grease or other disagreeable elements
Patient care setting
Direct patient care setting
Physical Effort
Typically sitting at desk or table
Typically standing or walking
Typically bending, crouching, stooping
Using tools requiring high dexterity
Occasional lifting (25 lbs or less)
Equipment
Office equipment
Lab/research equipment
Clinical/diagnostic equipment
Required Qualifications
Education:
Master's degree
Certifications /Professional Licenses :
Work Experience:
Skills:
Driver's License:
More About This Job
We are seeking a dedicated NP or PA to join our team. Below are additional requirements and information based on each role.
Required Qualifications:
Nurse Practitioner
- Master of Science in Nursing with emphasis in the Nurse Practitioner program.
- Advanced Practical Nurse licensure (or ability to successfully obtain licensure within three months of date of hire).
- Certain/additional certifications may be necessary based on area of specialty. Basic Life Support certification (Online Basic Life Support certifications, those without a skills assessment component, are not sufficient to meet the Basic Life Support requirements).
Physician Assistant
- Graduate of PA program.
- Current PA licensure to practice in the state of Missouri and/or Illinois, depending on location, or ability to obtain within three months of date of hire.
- Certain/additional certifications may be necessary based on area of specialty.
- Basic Life Support certification (Online BLS certifications, those without a skills assessment component, are not sufficient to meet the BLS requirements).
Preferred Qualifications
Education:
Master's degree - Nurse Practitioner, Master's degree - Physician Assistant Studies
Certifications /Professional Licenses :
Work Experience:
Skills:
Adaptability, Clinical Decision Making, Clinical Diagnostics, Communication, Customer Empathy, Detail-Oriented, Disease Management, Epic EHR, Family Support, HIPAA Compliance, Interpersonal Communication, Interpersonal Relationships, Multitasking, Organizing, Patient Care, Patient Education, Patient Evaluations, Patient Management, Pharmacology, Preventive Care, Teamwork, Time ManagementGrade
S31Salary Range
$97,000.00 - $174,600.00 / Annually The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ .
Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.Benefits Statement
Personal
Up to 22 days of vacation, 10 recognized holidays, and sick time.
Competitive health insurance packages with priority appointments and lower copays/coinsurance.
Take advantage of our free Metro transit U-Pass for eligible employees.
WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity or shared ancestry, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information. As a federal contractor, the university maintains affirmative action programs to implement its equal employment opportunity policy for individuals with disabilities and protected veterans, in accordance with Section 503 of the Rehabilitation Act of 1973, as amended, and the Vietnam Era Veterans’ Readjustment Assistance Act of 1974 (VEVRAA), as amended.See All 100 Nurse Practitioner Or Physician Assistant Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find JobsNurse Practitioner Or Physician Assistant Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Nurse Practitioner Or Physician Assistant Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- Mercy35

- CoxHealth9

- BJC HealthCare8

- Washington University in St. Louis7

- GoHealth Urgent Care4

Top Industries Hiring
- Healthcare & Medical Services
- Insurance
- Education
What Missouri Employers Look For
The qualifications that appear most often in nurse practitioner or physician assistant jobs across Missouri.
- Active Missouri nurse practitioner or physician assistant license or compact license recognized in Missouri
- Master's degree or doctoral degree in nursing or physician assistant studies required
- National certification from AANP, ANCC, or NCCPA required for all positions
- Current BLS and ACLS certification required prior to start date
- Minimum one to two years of clinical experience preferred for most openings
- Experience with electronic health records systems such as Epic or Cerner strongly preferred
Nurse Practitioner Or Physician Assistant Jobs in Missouri: Frequently Asked Questions
How do you become a nurse practitioner or physician assistant in Missouri?
Nurse practitioners in Missouri must hold a master's or doctoral degree, pass a national certification exam through AANP or ANCC, and obtain a license from the Missouri State Board of Nursing. Physician assistants must graduate from an accredited PA program, pass the PANCE through NCCPA, and register with the Missouri State Board of Registration for the Healing Arts. Both roles require a written collaborative practice agreement with a supervising physician in Missouri.
Which companies hire nurse practitioner or physician assistants in Missouri?
Employers hiring nurse practitioner or physician assistants in Missouri right now include Mercy, CoxHealth, and BJC HealthCare, based on current listings on Migrate Mate as of October 2026. Missouri's large integrated health systems and federally qualified health centers consistently post among the highest volumes of openings across the state.
Which Missouri cities have the most nurse practitioner or physician assistant jobs?
St. Louis, Springfield, and Kansas City have the most nurse practitioner or physician assistant openings in Missouri. Kansas City and St. Louis lead because of their dense concentration of major health systems, academic medical centers, and multispecialty group practices, while Columbia draws strong hiring volumes through MU Health Care and its surrounding regional referral network.
Are there remote nurse practitioner or physician assistant jobs in Missouri?
Yes, but they're rare. About 42% of nurse practitioner or physician assistant openings tied to Missouri are remote or hybrid as of October 2026, reflecting how hands-on clinical care limits full remote work for most roles. The positions most likely to offer remote arrangements are in telehealth, behavioral health consulting, and utilization review.
How can I get hired as a nurse practitioner or physician assistant in Missouri with little or no experience?
The most realistic entry path is applying to new-graduate or residency programs run by large Missouri health systems, including BJC HealthCare and MU Health Care, which offer structured NP and PA residencies in primary care and hospital medicine. Candidates who held roles as registered nurses, paramedics, or surgical technologists often transition more readily. Completing your Missouri collaborative practice agreement paperwork early and holding an active Epic certification strengthens any application from a new graduate.
Where can I find and apply to nurse practitioner or physician assistant jobs in Missouri?
You can find and apply to nurse practitioner or physician assistant jobs in Missouri on Migrate Mate, which lists current Missouri openings updated regularly. Find roles that fit your specialty, experience level, and preferred location, then apply directly to the employer without any intermediary step.
See All 100 Nurse Practitioner Or Physician Assistant Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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