Nurse Practitioner Or Physician Assistant Jobs in St. Louis, MO

Nurse Practitioner Or Physician Assistant jobs in St. Louis are in strong demand, concentrated in the Cortex Innovation Community, Forest Park Southeast, and downtown medical corridor across health systems, federally qualified health centers, and urgent care networks. Employers actively hiring include Mercy, Washington University in St. Louis, and BJC HealthCare. See the openings below and apply to the ones that match your experience.

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Overview

Open roles100
Top employerMercy
Work type69% On-site
Top credentialDoctoral degree
Companies hiring6

Showing 5 of 100+ Nurse Practitioner Or Physician Assistant jobs

Nurse Practitioner or Physician Assistant (Hybrid) - Breast Oncology
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New 17h ago
Nurse Practitioner or Physician Assistant (Hybrid) - Breast Oncology
Washington University in St. Louis
St. Louis, Missouri
Allied Health
Healthcare Administration
Nursing
$97k - $175k/yr
Hybrid
BLS Certification
10,000+

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Physician Assistant or Nurse Practitioner - PRN
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Added 4d ago
Physician Assistant or Nurse Practitioner - PRN
GoHealth Urgent Care
St. Louis, Missouri
Allied Health
Healthcare Administration
Nursing
Master's degree
501-1,000

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Advanced Practice Provider - Nurse Practitioner or Physician Assistant
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Added 4d ago
Advanced Practice Provider - Nurse Practitioner or Physician Assistant
Shriners Children's
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
PALS Certification
5,001-10,000

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Nurse Practitioner or Physician Assistant – Emergency Department, Mercy Hospital South
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Added 5d ago
Nurse Practitioner or Physician Assistant – Emergency Department, Mercy Hospital South
Mercy
St. Louis, Missouri
Allied Health
Clinical Support
Healthcare Administration
10,000+

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Nurse Practitioner or Physician Assistant for Hospitalist at Missouri Baptist Medical Center, 7on/7off, Days
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Added 6d ago
Nurse Practitioner or Physician Assistant for Hospitalist at Missouri Baptist Medical Center, 7on/7off, Days
BJC HealthCare
St. Louis, Missouri
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
$126k.6 - $171k.59/yr
Doctoral degree
10,000+

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Nurse Practitioner Or Physician Assistant Job Market in St. Louis

Who's Hiring

  • Mercy42
  • Washington University in St. Louis26
  • BJC HealthCare16
  • Shriners Children's5
  • GoHealth Urgent Care5

Top Industries Hiring

  • Education

Nurse Practitioner Or Physician Assistant Jobs in St. Louis: Frequently Asked Questions

How do I get a nurse practitioner or physician assistant job in St. Louis?

The strongest hiring in St. Louis comes from major health systems anchored near Forest Park, community health centers serving north and south city neighborhoods, and the growing cluster of specialty practices and urgent care groups in the western suburbs. Candidates who hold a relevant board certification, have experience with underserved or high-volume patient populations, and can demonstrate familiarity with Epic or other major EHR systems tend to move faster through local hiring processes.

Which companies hire nurse practitioner or physician assistants in St. Louis?

St. Louis nurse practitioner or physician assistant roles are posted by Mercy, Washington University in St. Louis, and BJC HealthCare and others right now, based on current listings on Migrate Mate as of October 2026. The local market includes large academic medical centers, regional hospital groups, federally qualified health centers, and an expanding network of independent specialty and urgent care practices.

Are there remote nurse practitioner or physician assistant jobs in St. Louis?

Remote work is limited for nurse practitioners and physician assistants because most roles require direct patient care, though telehealth-focused positions do exist. About 31% of nurse practitioner or physician assistant openings tied to St. Louis are remote or hybrid as of October 2026, mostly in telephonic triage, chronic care management, and utilization review. Those segments draw the largest share of remote-eligible postings from St. Louis-based insurers and managed care organizations.

How can I get a nurse practitioner or physician assistant job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is through a new graduate residency or fellowship program offered by the larger health systems near the medical school corridor, where structured onboarding bridges the gap from clinical training to independent practice. Community health centers serving areas like north St. Louis and the Dutchtown neighborhood frequently recruit new graduates and offer mentorship-heavy environments. Completing clinical rotations locally and building relationships with preceptors at St. Louis institutions gives new graduates a meaningful advantage over out-of-market applicants.

Which industries hire the most nurse practitioner or physician assistants in St. Louis?

The sectors hiring the most nurse practitioner or physician assistants in St. Louis are Education, based on current listings on Migrate Mate as of October 2026. St. Louis's concentration of academic medical centers, a historically strong primary care safety net, and steady growth in outpatient specialty and urgent care networks all drive sustained demand across those sectors.

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