Nurse Practitioner Or Physician Assistant Jobs in St. Louis, MO

Nurse Practitioner Or Physician Assistant jobs in St. Louis are in strong demand, concentrated in the Cortex Innovation Community, Forest Park Southeast, and downtown medical corridor across health systems, federally qualified health centers, and urgent care networks. Employers actively hiring include Mercy, Washington University in St. Louis, and BJC HealthCare. See the openings below and apply to the ones that match your experience.

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Overview

Open roles89
Top employerMercy
Work type100% On-site
Top credentialBLS Certification
Companies hiring4

Showing 5 of 89+ Nurse Practitioner Or Physician Assistant jobs

Mercy
Nurse Practitioner or Physician Assistant – Hospitalist (Nights), Mercy Hospital St. Louis
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Mercy
Added 6d ago
Nurse Practitioner or Physician Assistant – Hospitalist (Nights), Mercy Hospital St. Louis
Mercy
St. Louis, Missouri
Clinical Support
Healthcare Administration
Medical Specialists
10,000+

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Mercy
Nurse Practitioner or Physician Assistant – Colon and Rectal, Mercy Hospital South
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Mercy
Added 1w ago
Nurse Practitioner or Physician Assistant – Colon and Rectal, Mercy Hospital South
Mercy
St. Louis, Missouri
Allied Health
Clinical Support
Healthcare Administration
10,000+

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Mercy
Nurse Practitioner or Physician Assistant – Electrophysiology, Mercy Hospital St. Louis
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Mercy
Added 1w ago
Nurse Practitioner or Physician Assistant – Electrophysiology, Mercy Hospital St. Louis
Mercy
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
10,000+

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Mercy
Nurse Practitioner or Physician Assistant - Primary Care Mercy Clinic Olive Mason
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Mercy
Added 2w ago
Nurse Practitioner or Physician Assistant - Primary Care Mercy Clinic Olive Mason
Mercy
St. Louis, Missouri
Allied Health
Healthcare Administration
Nursing
10,000+

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Mercy
Nurse Practitioner or Physician Assistant – Cardiology, Mercy Hospital St. Louis
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Mercy
Added 2w ago
Nurse Practitioner or Physician Assistant – Cardiology, Mercy Hospital St. Louis
Mercy
St. Louis, Missouri
Clinical Support
Healthcare Administration
Medical Specialists
10,000+

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See All 89 Nurse Practitioner Or Physician Assistant Jobs in St. Louis

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Nurse Practitioner Or Physician Assistant Job Market in St. Louis

Who's Hiring

  • Mercy
    Mercy39
  • Washington University in St. Louis
    Washington University in St. Louis36
  • BJC HealthCare
    BJC HealthCare11
  • Vituity
    Vituity4

Top Industries Hiring

  • Education
  • Healthcare & Medical Services

Nurse Practitioner Or Physician Assistant Jobs in St. Louis: Frequently Asked Questions

How do I get a nurse practitioner or physician assistant job in St. Louis?

The strongest hiring in St. Louis comes from major health systems anchored near Forest Park, community health centers serving north and south city neighborhoods, and the growing cluster of specialty practices and urgent care groups in the western suburbs. Candidates who hold a relevant board certification, have experience with underserved or high-volume patient populations, and can demonstrate familiarity with Epic or other major EHR systems tend to move faster through local hiring processes.

Which companies hire nurse practitioner or physician assistants in St. Louis?

St. Louis nurse practitioner or physician assistant roles are posted by Mercy, Washington University in St. Louis, and BJC HealthCare and others right now, based on current listings on Migrate Mate as of August 2026. The local market includes large academic medical centers, regional hospital groups, federally qualified health centers, and an expanding network of independent specialty and urgent care practices.

Are there remote nurse practitioner or physician assistant jobs in St. Louis?

Remote work is limited for nurse practitioners and physician assistants because most roles require direct patient care, though telehealth-focused positions do exist. About 0% of nurse practitioner or physician assistant openings tied to St. Louis are remote or hybrid as of August 2026, mostly in telephonic triage, chronic care management, and utilization review. Those segments draw the largest share of remote-eligible postings from St. Louis-based insurers and managed care organizations.

How can I get a nurse practitioner or physician assistant job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is through a new graduate residency or fellowship program offered by the larger health systems near the medical school corridor, where structured onboarding bridges the gap from clinical training to independent practice. Community health centers serving areas like north St. Louis and the Dutchtown neighborhood frequently recruit new graduates and offer mentorship-heavy environments. Completing clinical rotations locally and building relationships with preceptors at St. Louis institutions gives new graduates a meaningful advantage over out-of-market applicants.

Which industries hire the most nurse practitioner or physician assistants in St. Louis?

The sectors hiring the most nurse practitioner or physician assistants in St. Louis are Education and Healthcare & Medical Services, based on current listings on Migrate Mate as of August 2026. St. Louis's concentration of academic medical centers, a historically strong primary care safety net, and steady growth in outpatient specialty and urgent care networks all drive sustained demand across those sectors.

See All 89 Nurse Practitioner Or Physician Assistant Jobs in St. Louis

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