Principal Medical Writer Jobs in Missouri
Principal Medical Writer jobs in Missouri are concentrated in St. Louis and Kansas City, where life sciences anchors like Pfizer, Bayer, and Express Scripts maintain substantial regulatory and clinical operations. Demand is strongest for writers with oncology, cardiovascular, and rare disease expertise, reflecting the therapeutic focuses of Missouri's largest biopharma employers. Roles at the principal level require demonstrated leadership on regulatory submissions, clinical study reports, and cross-functional authoring teams. See the openings below and apply to the ones that match your experience.
Find Principal Medical Writer JobsOverview
Showing 5 of 14+ Principal Medical Writer jobs











We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.
Position Summary:
This is a remote position that can sit anywhere in the United States.
Aetna’s Medicaid Proposal Writer supports the business by creating and executing strategic writing in response to Medicaid request for proposals (RFP) and requests for information (RFI).
The Proposal Writer:
Drafts proposal responses for functional and operational topics such as Claims, Staffing, Finance, Corporate Capabilities, Account Management, and Resumes.
Partners with Proposal Managers, Capture Managers, and SMEs to gather information, develop content, and support proposal response development.
Collaborates and interviews subject matter experts (SMEs) to identify and obtain new information to create compliant and compelling responses.
Applies bid guidance, proposal requirements, and internal quality standards to assigned sections while continuing to develop proposal writing expertise.
Actively participates in kick-off meetings, color team reviews, status meetings, and critical milestones throughout the entire proposal process as defined by the proposal timeline.
Adheres to internal processes and communicates proposal related risks to the proposal team.
Reviews Pink and Red Team reviewer comments and prepares drafts for discussion during Pink and Red Team Review Meetings.
Seeks and incorporates feedback from proposal leaders, reviewers, and SMEs to continuously strengthen writing, compliance, and strategic messaging skills.
Builds knowledge of Medicaid programs, Aetna solutions, procurement processes, and proposal best practices.
Required Qualifications:
Exposure Medicaid, Medicare, managed care, government procurements, or healthcare operations.
Willingness to learn and build expertise across Medicaid business. - Intermediate to advanced knowledge of Microsoft Office, including Word, PowerPoint and Excel.
Demonstrated ability to build relationships, integrate strategies, and connect the dots between messages, timing and activities under other leaders’ influence.
A strong command of the English language with proficiency in grammar, flow, clarity, tone, and voice.
Proven facilitation skills.
Excellent reading comprehension and experience with reading and summarizing complex documents, including contractual and legal documents.
Strong time management, planning, and coordination skills.
Ability to work independently to produce high-quality results that meet needs of internal and external customer expectations under tight timeframes.
Strong team collaboration skills, including SMEs and other contributors, writing team, and production team.
Ability to adapt to rapidly changing priorities through the identification and execution on creative solutions.
Ability to accept and apply feedback constructively.
Intermediate proficiency with Microsoft Word, PowerPoint, and Excel.
Interest in building expertise in Medicaid programs, managed care, and healthcare procurements.
Preferred Qualifications:
1-3 years of experience creating compelling, audience-aware Medicaid proposal responses.
APMP Foundation Certification preferred or willingness to pursue certification.
Education:
Bachelor’s degree or equivalent experience.
Anticipated Weekly Hours
40Time Type
Full timePay Range
The typical pay range for this role is:
$54,300.00 - $119,340.00This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors. This position is eligible for a CVS Health bonus, commission or short-term incentive program in addition to the base pay range listed above.
Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.
Great benefits for great people
We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.
This full‑time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well‑being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.
Additional details about available benefits are provided during the application process and on Benefits Moments.
We anticipate the application window for this opening will close on: 08/10/2026
Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.
See All 14 Principal Medical Writer Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Principal Medical Writer JobsPrincipal Medical Writer Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Principal Medical Writer Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Consumer Goods
What Missouri Employers Look For
The qualifications that appear most often in principal medical writer jobs across Missouri.
- Advanced degree in life sciences, pharmacy, or a related biomedical field
- Seven or more years of regulatory or clinical medical writing experience
- Demonstrated lead authorship on CTDs, INDs, NDAs, or BLAs
- Expertise in ICH guidelines and FDA regulatory submission standards
- Strong experience mentoring junior writers and managing document timelines
- Proficiency with publishing tools such as Veeva Vault or similar document management systems
Principal Medical Writer Jobs in Missouri: Frequently Asked Questions
How do you become a principal medical writer in Missouri?
The principal medical writer role in Missouri has no state-issued license or exam requirement, so the path runs through education and experience. Most Missouri employers expect an advanced degree in life sciences, medicine, pharmacy, or a closely related field. From there, candidates build years of regulatory or clinical writing experience before being considered at the principal level. A portfolio of completed regulatory submissions carries significant weight with Missouri hiring teams at biopharma companies, CROs, and medical device manufacturers.
Which companies hire principal medical writers in Missouri?
Companies currently hiring principal medical writers in Missouri include TARKETT, CVS Health, and EquipmentShare, per current listings on Migrate Mate as of July 2026. Missouri's concentration of pharmaceutical headquarters and contract research organizations in the St. Louis metro creates steady demand at the senior authorship level.
Which Missouri cities have the most principal medical writer jobs?
The cities with the most principal medical writer openings in Missouri are Kansas City, St. Louis, and Missouri. St. Louis leads because it houses the regional and global headquarters of major pharmaceutical and biotech firms, while Kansas City draws openings through its growing CRO presence and large health systems that run clinical research programs requiring dedicated senior authorship support.
Are there remote principal medical writer jobs in Missouri?
Yes, and more than most fields. Medical writing is document-driven and requires no on-site lab or clinical presence, making it one of the more remote-compatible roles in the life sciences. About 38% of principal medical writer openings tied to Missouri are remote or hybrid as of July 2026, reflecting how widely biopharma and CRO employers have embraced distributed authoring teams. Regulatory submissions and clinical study reports, the core outputs at this level, are particularly well suited to remote delivery.
How can I get hired as a principal medical writer in Missouri with little or no experience?
The most realistic entry path is a medical writing associate or junior regulatory writer role at a Missouri-based contract research organization or pharmaceutical company, where structured mentorship programs exist for candidates coming from clinical, scientific, or pharmacy backgrounds. Large St. Louis employers and CROs with Missouri offices regularly post associate medical writer openings aimed at candidates with advanced degrees but limited industry writing experience. Building a portfolio through academic publications, clinical trial summaries, or regulatory coursework from organizations like the American Medical Writers Association strengthens applications considerably at this stage.
Where can I find and apply to principal medical writer jobs in Missouri?
You can find and apply to principal medical writer jobs in Missouri on Migrate Mate, which lists current Missouri openings updated regularly. Search for roles that fit your therapeutic area experience and seniority level, then apply directly to the ones that match. No account creation is needed to see the listings.
See All 14 Principal Medical Writer Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Principal Medical Writer Jobs