Practice Assistant Jobs in Missouri
Practice assistant jobs in Missouri are concentrated in healthcare settings, including physician offices, dental practices, and outpatient clinics, with demand at every level from entry-level roles to experienced clinical support positions. Kansas City, St. Louis, and Springfield are the largest hiring markets, with established employers like BJC HealthCare, Saint Luke's Health System, and Mercy Health consistently posting openings across Missouri. The most in-demand specialties include dental assisting, medical office support, and behavioral health practice assistance. See the openings below and apply to the ones that match your experience.
Find Practice Assistant JobsOverview
Open roles12
Top employerChildren's Mercy Hospitals & Clinics
Top cityKansas City, MO
Cities hiring4
Work type100% On-site
Top industryHealthcare
Showing 5 of 12+ Practice Assistant jobs
Advanced Practice Provider (PNP-PC/Physician Assistant) - Outpatient Nephrology Clinic
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Added 1d ago
Children's Mercy Hospitals & Clinics
Advanced Practice Provider (PNP-PC/Physician Assistant) - Outpatient Nephrology Clinic
Kansas City, Missouri
Added 1d ago
S
Experienced Dental Assistant – Full-Time| Private Practice
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S
Added 2d ago
Smith/Wallace Restorative Dentistry
Experienced Dental Assistant – Full-Time| Private Practice
St. Louis, Missouri
Added 2d ago
Medical Assistant - Trauma Practice
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Added 1w ago
Saint Luke's
Medical Assistant - Trauma Practice
Kansas City, Missouri
Added 1w ago
Advanced Practice Provider - Physician's Assistant (PA)
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Added 1w ago
Landmark Hospitals
Advanced Practice Provider - Physician's Assistant (PA)
Columbia, Missouri
Added 1w ago
Advanced Practice Provider (PNP/Physician Assistant) - Emergency Department - Weekend Option
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Added 2w ago
Children's Mercy Hospitals & Clinics
Advanced Practice Provider (PNP/Physician Assistant) - Emergency Department - Weekend Option
Kansas City, Missouri
Added 2w ago
Added 1d ago
Advanced Practice Provider (PNP-PC/Physician Assistant) - Outpatient Nephrology Clinic
Children's Mercy Hospitals & Clinics·Kansas City, Missouri
Job functions:
Master's degree
5,001-10,000 employees
Job Description
Thanks for your interest in Children's Mercy!:
Children’s Mercy is in the heart of Kansas City – a metro abounding in cultural experiences, vibrant communities and thriving businesses. This is where our patients and families live, work and play. This is a community that has embraced our hospital and we strive to say thanks by giving back. As a leader in children’s health, we engage in meaningful programs and partnerships throughout the region so that we can improve the lives of children beyond the walls of our hospital.
Overview:
As one of the top-ranked kidney care programs in the nation, the Division of Pediatric Nephrology at Children’s Mercy provides family-centered care for children and teens with kidney diseases.
Proficiently provides comprehensive, evidence-based advanced practice nursing care based on the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement for patient populations.
The APP provides outpatient nephrology care for children with a variety of kidney diagnoses in the outpatient nephrology clinic and via telehealth encounters.
Diagnoses include, but are not limited to, enuresis, hypertension, genetic kidney disorders, glomerulonephritis, chronic kidney disease, stages I-IV, congenital anomalies, and dysplasia.
Advanced Practice Registered Nurses II (APRN-II) provides proficient, comprehensive, evidence-based advanced practice nursing to address the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement. An APRN II obtains a comprehensive health history; performs physical examination; formulates a plan of care and treatment; prescribes/performs diagnostic and therapeutic interventions and procedures; and participates in patient and family education. Each APRN-II demonstrates professional leadership and participates in evidenced-based practice, quality improvement, and/or research activities, and organizational development.
At Children’s Mercy, we are committed to ensuring that everyone feels welcomed within our walls. A successful candidate for this position will join us as we strive to create a workplace that reflects the community we serve, as well as our core values of kindness, curiosity, inclusion, team and integrity.
Additionally, it’s important to us that we remain transparent with all potential job candidates. Because we value the safety of the patients and families we serve, as well as the Children’s Mercy staff, we want to let you know that the seasonal influenza vaccine is a condition of employment for all employees in our organization. New employees must be willing to be vaccinated if found non-immune to measles, mumps, rubella (MMR) and chicken pox (varicella) and/or without evidence of tetanus, diphtheria, acellular pertussis (Tdap) vaccination since 2005. If you are selected for this position, you will be asked to supply your immunization records as proof of vaccination. If you and have any concerns about receiving these vaccines, medical and/or religious exemptions can be further discussed with Human Resources.
Responsibilities: - Clinical Practice: proficiently provides comprehensive, evidence-based advanced practice nursing care based on the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement. - Professional Leadership: advances the practice of nursing by inspiring others to positively impact the care of children and families in our community. - Evidenced-based Practice/QI/Research Inquiry: improves patient/family outcomes by utilizing evidence to translate science to practice. - Organizational Development: influences organizational policy in order to achieve and sustain practice improvements and strategic initiatives. Qualifications:
CM is committed to creating a workforce that supports the diverse backgrounds of our patients and families. We know that our greatest strengths come from the people who make up our team, so we hire great people from a wide variety of backgrounds, not just because it’s the right thing to do, but because it makes our hospital stronger and our patient care more compassionate.
If you share our values and our enthusiasm for service, you will find a home at CM. In recruiting for our team, we welcome the unique contributions that you can bring, including education, ideas, culture, and beliefs.
Do you envision finding a meaningful role with an inclusive and compassionate team? At Children’s Mercy, we believe in making a difference in the lives of all children and shining a light of hope to the patients and families we serve. Our employees make the difference, which is why we have been recognized by U.S. News & World Report as a top pediatric hospital, for eleven consecutive years.
Children’s Mercy is in the heart of Kansas City – a metro abounding in cultural experiences, vibrant communities and thriving businesses. This is where our patients and families live, work and play. This is a community that has embraced our hospital and we strive to say thanks by giving back. As a leader in children’s health, we engage in meaningful programs and partnerships throughout the region so that we can improve the lives of children beyond the walls of our hospital.
Nephrology
As one of the top-ranked kidney care programs in the nation, the Division of Pediatric Nephrology at Children’s Mercy provides family-centered care for children and teens with kidney diseases.
Proficiently provides comprehensive, evidence-based advanced practice nursing care based on the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement for patient populations.
The APP provides outpatient nephrology care for children with a variety of kidney diagnoses in the outpatient nephrology clinic and via telehealth encounters.
Diagnoses include, but are not limited to, enuresis, hypertension, genetic kidney disorders, glomerulonephritis, chronic kidney disease, stages I-IV, congenital anomalies, and dysplasia.
Advanced Practice Registered Nurses II (APRN-II) provides proficient, comprehensive, evidence-based advanced practice nursing to address the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement. An APRN II obtains a comprehensive health history; performs physical examination; formulates a plan of care and treatment; prescribes/performs diagnostic and therapeutic interventions and procedures; and participates in patient and family education. Each APRN-II demonstrates professional leadership and participates in evidenced-based practice, quality improvement, and/or research activities, and organizational development.
At Children’s Mercy, we are committed to ensuring that everyone feels welcomed within our walls. A successful candidate for this position will join us as we strive to create a workplace that reflects the community we serve, as well as our core values of kindness, curiosity, inclusion, team and integrity.
Additionally, it’s important to us that we remain transparent with all potential job candidates. Because we value the safety of the patients and families we serve, as well as the Children’s Mercy staff, we want to let you know that the seasonal influenza vaccine is a condition of employment for all employees in our organization. New employees must be willing to be vaccinated if found non-immune to measles, mumps, rubella (MMR) and chicken pox (varicella) and/or without evidence of tetanus, diphtheria, acellular pertussis (Tdap) vaccination since 2005. If you are selected for this position, you will be asked to supply your immunization records as proof of vaccination. If you and have any concerns about receiving these vaccines, medical and/or religious exemptions can be further discussed with Human Resources.
- Master's Degree and 1-2 years experience 1-2 years pediatric APRN experience with Masters. Exceptions considered on a case-by-case basis within preferred specialty. or
- Doctorate in Nursing Practice (DNP) - preferred and 1-2 years experience 1 year pediatric APRN experience. Exceptions considered on a case-by-case basis within preferred specialty.
- Licensed RN - Kansas, Registered Nurse Multistate License Kansas required upon hire
- Licensed RN - MO, Registered Nurse Multistate License Missouri required upon hire
- RN Compact license for all states besides KS and MO
- APRN board certification congruent with population and practice setting (see policy statement: Advanced Practice Registered Nurse Roles and Practice Setting) Required Upon Hire
- Successful completion of national board certification in one of the following:
- Certified Nurse Practitioner (CNP) in MO & KS Required Upon Hire
- Refer to Nursing and Advanced Practice Provider Licensure and Certification policy for required Life Support Certifications Required Upon Hire
-
PNP-Primary Care will be required
- candidate will have two years to enroll/be accepted in a program and five years to complete the program
- Specialty Certification relevant to unit’s patient population (determined by Nurse Manager/Director) Preferred
Children’s Mercy hires individuals based on their job skills, expertise and ability to maintain professional relationships with fellow employees, patients, parents and visitors. A personal interview, formal education and training, previous work experience, references and a criminal background investigation are all factors used to select the best candidates. The hospital does not discriminate against prospective or current employees based on the race, color, religion, sex, national origin, age, disability, creed, genetic information, sexual orientation, gender identity or expression, ancestry or veteran status. A drug screen will be performed upon hire. Children’s Mercy is smoke and tobacco free.
CM is committed to creating a workforce that supports the diverse backgrounds of our patients and families. We know that our greatest strengths come from the people who make up our team, so we hire great people from a wide variety of backgrounds, not just because it’s the right thing to do, but because it makes our hospital stronger and our patient care more compassionate.
If you share our values and our enthusiasm for service, you will find a home at CM. In recruiting for our team, we welcome the unique contributions that you can bring, including education, ideas, culture, and beliefs.
Children's Mercy Hospitals & Clinics
Advanced Practice Provider (PNP-PC/Physician Assistant) - Outpatient Nephrology Clinic
Kansas City, Missouri
Added 1d ago5,001-10,000 employees
Job functions:
Master's degree
Job Description
Thanks for your interest in Children's Mercy!:
Children’s Mercy is in the heart of Kansas City – a metro abounding in cultural experiences, vibrant communities and thriving businesses. This is where our patients and families live, work and play. This is a community that has embraced our hospital and we strive to say thanks by giving back. As a leader in children’s health, we engage in meaningful programs and partnerships throughout the region so that we can improve the lives of children beyond the walls of our hospital.
Overview:
As one of the top-ranked kidney care programs in the nation, the Division of Pediatric Nephrology at Children’s Mercy provides family-centered care for children and teens with kidney diseases.
Proficiently provides comprehensive, evidence-based advanced practice nursing care based on the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement for patient populations.
The APP provides outpatient nephrology care for children with a variety of kidney diagnoses in the outpatient nephrology clinic and via telehealth encounters.
Diagnoses include, but are not limited to, enuresis, hypertension, genetic kidney disorders, glomerulonephritis, chronic kidney disease, stages I-IV, congenital anomalies, and dysplasia.
Advanced Practice Registered Nurses II (APRN-II) provides proficient, comprehensive, evidence-based advanced practice nursing to address the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement. An APRN II obtains a comprehensive health history; performs physical examination; formulates a plan of care and treatment; prescribes/performs diagnostic and therapeutic interventions and procedures; and participates in patient and family education. Each APRN-II demonstrates professional leadership and participates in evidenced-based practice, quality improvement, and/or research activities, and organizational development.
At Children’s Mercy, we are committed to ensuring that everyone feels welcomed within our walls. A successful candidate for this position will join us as we strive to create a workplace that reflects the community we serve, as well as our core values of kindness, curiosity, inclusion, team and integrity.
Additionally, it’s important to us that we remain transparent with all potential job candidates. Because we value the safety of the patients and families we serve, as well as the Children’s Mercy staff, we want to let you know that the seasonal influenza vaccine is a condition of employment for all employees in our organization. New employees must be willing to be vaccinated if found non-immune to measles, mumps, rubella (MMR) and chicken pox (varicella) and/or without evidence of tetanus, diphtheria, acellular pertussis (Tdap) vaccination since 2005. If you are selected for this position, you will be asked to supply your immunization records as proof of vaccination. If you and have any concerns about receiving these vaccines, medical and/or religious exemptions can be further discussed with Human Resources.
Responsibilities: - Clinical Practice: proficiently provides comprehensive, evidence-based advanced practice nursing care based on the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement. - Professional Leadership: advances the practice of nursing by inspiring others to positively impact the care of children and families in our community. - Evidenced-based Practice/QI/Research Inquiry: improves patient/family outcomes by utilizing evidence to translate science to practice. - Organizational Development: influences organizational policy in order to achieve and sustain practice improvements and strategic initiatives. Qualifications:
CM is committed to creating a workforce that supports the diverse backgrounds of our patients and families. We know that our greatest strengths come from the people who make up our team, so we hire great people from a wide variety of backgrounds, not just because it’s the right thing to do, but because it makes our hospital stronger and our patient care more compassionate.
If you share our values and our enthusiasm for service, you will find a home at CM. In recruiting for our team, we welcome the unique contributions that you can bring, including education, ideas, culture, and beliefs.
Do you envision finding a meaningful role with an inclusive and compassionate team? At Children’s Mercy, we believe in making a difference in the lives of all children and shining a light of hope to the patients and families we serve. Our employees make the difference, which is why we have been recognized by U.S. News & World Report as a top pediatric hospital, for eleven consecutive years.
Children’s Mercy is in the heart of Kansas City – a metro abounding in cultural experiences, vibrant communities and thriving businesses. This is where our patients and families live, work and play. This is a community that has embraced our hospital and we strive to say thanks by giving back. As a leader in children’s health, we engage in meaningful programs and partnerships throughout the region so that we can improve the lives of children beyond the walls of our hospital.
Nephrology
As one of the top-ranked kidney care programs in the nation, the Division of Pediatric Nephrology at Children’s Mercy provides family-centered care for children and teens with kidney diseases.
Proficiently provides comprehensive, evidence-based advanced practice nursing care based on the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement for patient populations.
The APP provides outpatient nephrology care for children with a variety of kidney diagnoses in the outpatient nephrology clinic and via telehealth encounters.
Diagnoses include, but are not limited to, enuresis, hypertension, genetic kidney disorders, glomerulonephritis, chronic kidney disease, stages I-IV, congenital anomalies, and dysplasia.
Advanced Practice Registered Nurses II (APRN-II) provides proficient, comprehensive, evidence-based advanced practice nursing to address the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement. An APRN II obtains a comprehensive health history; performs physical examination; formulates a plan of care and treatment; prescribes/performs diagnostic and therapeutic interventions and procedures; and participates in patient and family education. Each APRN-II demonstrates professional leadership and participates in evidenced-based practice, quality improvement, and/or research activities, and organizational development.
At Children’s Mercy, we are committed to ensuring that everyone feels welcomed within our walls. A successful candidate for this position will join us as we strive to create a workplace that reflects the community we serve, as well as our core values of kindness, curiosity, inclusion, team and integrity.
Additionally, it’s important to us that we remain transparent with all potential job candidates. Because we value the safety of the patients and families we serve, as well as the Children’s Mercy staff, we want to let you know that the seasonal influenza vaccine is a condition of employment for all employees in our organization. New employees must be willing to be vaccinated if found non-immune to measles, mumps, rubella (MMR) and chicken pox (varicella) and/or without evidence of tetanus, diphtheria, acellular pertussis (Tdap) vaccination since 2005. If you are selected for this position, you will be asked to supply your immunization records as proof of vaccination. If you and have any concerns about receiving these vaccines, medical and/or religious exemptions can be further discussed with Human Resources.
- Master's Degree and 1-2 years experience 1-2 years pediatric APRN experience with Masters. Exceptions considered on a case-by-case basis within preferred specialty. or
- Doctorate in Nursing Practice (DNP) - preferred and 1-2 years experience 1 year pediatric APRN experience. Exceptions considered on a case-by-case basis within preferred specialty.
- Licensed RN - Kansas, Registered Nurse Multistate License Kansas required upon hire
- Licensed RN - MO, Registered Nurse Multistate License Missouri required upon hire
- RN Compact license for all states besides KS and MO
- APRN board certification congruent with population and practice setting (see policy statement: Advanced Practice Registered Nurse Roles and Practice Setting) Required Upon Hire
- Successful completion of national board certification in one of the following:
- Certified Nurse Practitioner (CNP) in MO & KS Required Upon Hire
- Refer to Nursing and Advanced Practice Provider Licensure and Certification policy for required Life Support Certifications Required Upon Hire
-
PNP-Primary Care will be required
- candidate will have two years to enroll/be accepted in a program and five years to complete the program
- Specialty Certification relevant to unit’s patient population (determined by Nurse Manager/Director) Preferred
Children’s Mercy hires individuals based on their job skills, expertise and ability to maintain professional relationships with fellow employees, patients, parents and visitors. A personal interview, formal education and training, previous work experience, references and a criminal background investigation are all factors used to select the best candidates. The hospital does not discriminate against prospective or current employees based on the race, color, religion, sex, national origin, age, disability, creed, genetic information, sexual orientation, gender identity or expression, ancestry or veteran status. A drug screen will be performed upon hire. Children’s Mercy is smoke and tobacco free.
CM is committed to creating a workforce that supports the diverse backgrounds of our patients and families. We know that our greatest strengths come from the people who make up our team, so we hire great people from a wide variety of backgrounds, not just because it’s the right thing to do, but because it makes our hospital stronger and our patient care more compassionate.
If you share our values and our enthusiasm for service, you will find a home at CM. In recruiting for our team, we welcome the unique contributions that you can bring, including education, ideas, culture, and beliefs.
See All 12 Practice Assistant Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Practice Assistant JobsPractice Assistant Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Kansas City
8 jobsSt. Louis
2 jobsColumbia
1 jobO'Fallon
1 jobPractice Assistant Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
- Law & Legal Services
What Missouri Employers Look For
The qualifications that appear most often in practice assistant jobs across Missouri.
- Active Missouri registration or recognized credential relevant to the practice assistant specialty
- High school diploma or equivalent, with post-secondary certificate preferred for clinical roles
- Experience with electronic health record systems such as Epic or Cerner
- Strong knowledge of medical or dental terminology appropriate to the practice setting
- Ability to manage patient scheduling, insurance verification, and front-office workflows
- Effective written and verbal communication skills for coordinating with clinical staff and patients
Practice Assistant Jobs in Missouri: Frequently Asked Questions
How do you become a practice assistant in Missouri?
The path depends on the practice specialty. For dental assisting, Missouri does not require a state license but most employers expect a Dental Assisting National Board credential or completion of an accredited program. For medical practice assistants, a certificate from a Missouri community college or vocational program is the most common entry point. Those pursuing clinical roles should verify any facility-specific credentialing requirements with the Missouri Division of Professional Registration.
Which companies hire practice assistants in Missouri?
Employers hiring practice assistants in Missouri right now include Children's Mercy Hospitals & Clinics, Polsinelli, and Saint Luke's, based on current listings on Migrate Mate as of August 2026. Missouri's concentration of large regional health systems means hiring is steady throughout the year, particularly in outpatient and specialty clinic settings.
Which Missouri cities have the most practice assistant jobs?
The cities with the most practice assistant openings in Missouri are Kansas City, St. Louis, and Columbia. Kansas City and St. Louis dominate the market because they anchor Missouri's largest health systems and specialty care networks, while Springfield's significant regional medical infrastructure drives consistent demand in the southwest part of the state.
Are there remote practice assistant jobs in Missouri?
Yes, but they're rare. Practice assistant roles are largely hands-on and tied to clinical or front-office settings, so fully remote positions are limited. About 0% of practice assistant openings tied to Missouri are remote or hybrid as of August 2026, and those opportunities are most common in medical billing, insurance verification, and administrative coordination functions.
How can I get hired as a practice assistant in Missouri with little or no experience?
The most realistic entry path is completing a certificate program at a Missouri community college, such as those offered at Ozarks Technical Community College or St. Louis Community College, and applying directly to clinic support or patient services roles. Large Missouri health systems including BJC HealthCare and Mercy Health run new-graduate and entry-level hiring programs for clinical support staff. Candidates coming from adjacent roles like medical receptionist, pharmacy technician, or patient care technician also have a strong foothold, and earning a Certified Medical Administrative Assistant credential before applying gives a measurable edge.
Where can I find and apply to practice assistant jobs in Missouri?
You can find and apply to practice assistant jobs in Missouri on Migrate Mate, which lists current Missouri openings across practice specialties and hiring locations. Search the listings to find roles that match your background and apply directly to the ones that fit.
See All 12 Practice Assistant Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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