Practice Assistant Jobs in Illinois

Practice Assistant jobs in Illinois are in steady demand, with openings concentrated in medical and legal office settings across Chicago, Springfield, and Peoria. Large health systems like Northwestern Medicine, Advocate Health Care, and Rush University Medical Center are among the most consistent Illinois employers, alongside established law firms and multi-specialty clinics. The most sought-after specialties include clinical documentation, patient intake coordination, and legal practice support. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles43
Top employerUChicago Medicine
Top cityChicago, IL
Cities hiring25
Work type75% On-site
Top industryEducation

Showing 5 of 43+ Practice Assistant jobs

ROSIN EYECARE
Assistant Practice Manager
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ROSIN EYECARE
New 23h ago
Assistant Practice Manager
ROSIN EYECARE
Chicago, Illinois
Clinical Support
Healthcare Administration
Human Resources
$21 - $27/hr
High school diploma or GED
51-200

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Duly Health and Care
Lead Medical Assistant - Family Practice
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Duly Health and Care
Added 1d ago
Lead Medical Assistant - Family Practice
Duly Health and Care
Aurora, Illinois
Business Development
Growth Marketing
Marketing
$23.76 - $27.03/hr
CPR Certification
5,001-10,000

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P
Medical Assistant in Aesthetic Medical Practice (Part-Time)
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P
Added 1d ago
Medical Assistant in Aesthetic Medical Practice (Part-Time)
Pryor Health
Naperville, Illinois
Clinical Support
Healthcare Administration
Medical Assistant
$22 - $25/hr
On-Site

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OSF HealthCare
Medical Office Assistant Family Practice
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OSF HealthCare
Added 4d ago
Medical Office Assistant Family Practice
OSF HealthCare
Mendota, Illinois
Administrative & Office Support
Customer Service
Healthcare Administration
$18.85 - $21.21/hr
High school diploma or GED
10,000+

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Holland & Knight
Practice Assistant - Private Wealth Services
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Holland & Knight
Added 5d ago
Practice Assistant - Private Wealth Services
Holland & Knight
Chicago, Illinois
Compliance & Risk
Project Management
Quality Assurance & Testing (QA Testing)
$40 - $60/hr
Bachelor's degree
1,001-5,000

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See All 43 Practice Assistant Jobs in Illinois

Find roles in Illinois that match your experience and apply in just a few clicks.

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Practice Assistant Jobs by City in Illinois

Where Illinois roles are concentrated, by current openings.

Aurora
2 jobs
DeKalb
2 jobs
Loves Park
2 jobs
Naperville
2 jobs
Downers Grove
2 jobs
Harvey
1 job
Mokena
1 job
Ottawa
1 job

Practice Assistant Job Market in Illinois

A snapshot from current Illinois openings, updated as new roles post.

Who's Hiring

UChicago Medicine
UChicago Medicine7 open roles
OSF HealthCare
OSF HealthCare6 open roles
Duly Health and Care
Duly Health and Care5 open roles

Top Industries Hiring

  • Education
  • Law & Legal Services
  • Healthcare & Medical Services

What Illinois Employers Look For

The qualifications that appear most often in practice assistant jobs across Illinois.

  • Active Illinois licensure or certification recognized by the Illinois Department of Professional Regulation
  • Associate or bachelor's degree in health administration, business, or a related field
  • Proficiency in electronic health record systems such as Epic or Cerner
  • Minimum one to two years of administrative or clinical support experience
  • Strong written and verbal communication skills for patient and provider interaction
  • Familiarity with medical billing, coding, or legal documentation processes

Practice Assistant Jobs in Illinois: Frequently Asked Questions

How do you become a practice assistant in Illinois?

Most practice assistant roles in Illinois require at minimum a high school diploma, though an associate degree in medical assisting or healthcare administration gives candidates a strong edge. Clinical practice assistants may need certification through a nationally recognized body, which Illinois employers broadly accept. The Illinois Department of Professional Regulation oversees related allied health credentials. Many candidates also complete coursework in medical terminology, billing, and health records before applying.

Which companies hire practice assistants in Illinois?

Illinois practice assistant roles are posted by UChicago Medicine, OSF HealthCare, and Duly Health and Care and others right now, based on current listings on Migrate Mate as of August 2026. Illinois's dense concentration of hospital networks, specialty clinics, and law firms makes it one of the more active states for this role throughout the year.

Which Illinois cities have the most practice assistant jobs?

Chicago, Illinois, and Aurora have the most practice assistant openings in Illinois right now. Chicago dominates because of its size and its deep concentration of academic medical centers, large law firms, and corporate headquarters, while Springfield draws demand from state government health agencies and regional hospital systems, and Peoria anchors a strong cluster of multi-specialty medical practices in central Illinois.

Are there remote practice assistant jobs in Illinois?

Yes, but they're rare. Practice assistant work is largely on-site because it involves direct patient interaction, physical records management, and hands-on clinical or office support. About 25% of practice assistant openings tied to Illinois are remote or hybrid as of August 2026, and those positions tend to involve administrative coordination, scheduling, or documentation review rather than direct patient-facing duties.

How can I get hired as a practice assistant in Illinois with little or no experience?

The most realistic entry path is applying to patient service representative or medical receptionist roles at large Illinois health systems like Northwestern Medicine or Advocate Health Care, which regularly hire candidates without prior clinical experience and provide on-the-job training. Completing a medical assisting certificate program at a community college like Oakton College or Triton College also positions candidates well. Lateral moves from administrative assistant or customer service roles are common, and obtaining a basic medical terminology certificate gives entry-level applicants a measurable edge.

Where can I find and apply to practice assistant jobs in Illinois?

You can find and apply to practice assistant jobs in Illinois on Migrate Mate, which lists current Illinois openings across the state. Search the available roles, find the ones that match your experience and preferred location, and apply directly to the ones that fit.

See All 43 Practice Assistant Jobs in Illinois

Find roles in Illinois that match your experience and apply in just a few clicks.

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