Practice Assistant Jobs in Illinois
Practice Assistant jobs in Illinois are in steady demand, with openings concentrated in medical and legal office settings across Chicago, Springfield, and Peoria. Large health systems like Northwestern Medicine, Advocate Health Care, and Rush University Medical Center are among the most consistent Illinois employers, alongside established law firms and multi-specialty clinics. The most sought-after specialties include clinical documentation, patient intake coordination, and legal practice support. Scan the live roles below and apply to whichever ones fit.
Find Practice Assistant JobsOverview
Showing 5 of 44+ Practice Assistant jobs









If you have additional questions, contact recruiter at:
HSHS Medical Group is seeking a Board-Certified/Board-Eligible Nurse Practitioner or Physician Assistant to join our growing Gastroenterology team in O’Fallon, Illinois. This role primarily focuses on outpatient clinic responsibilities with occasional hospital rounding as needed.
You’ll be part of a well-established and expanding practice within the Hospital Sisters Health System, working closely with a multidisciplinary team to deliver high-quality patient care.
Practice Highlights:
- Well established, growing practice.
- No holidays or weekends
- No required call
- EPIC EMR
- Clinics are within the hospitals, providing access to all imaging, labs, scans, etc. needed.
- Ample training time provided with GI team.
Position Requirements:
- Unrestricted Illinois license and DEA prior to start
- Board Certified
- 2+ years of provider work experience is strongly preferred.
- Experience in GI is preferred, but experience in other specialties will also be
Compensation & Benefits Package:
- Base Salary: $128,153 With Bonus Earning Potential
- Paid time off with holidays accrued bi-weekly
- CME reimbursement + days available per fiscal year
- Opportunities to earn productivity and patient outcome/patient satisfaction
- Sign on bonus and relocation assistance both available
Core Function: Provider
Education Qualifications
- Master’s degree in Nursing is required.
- Bachelor’s Degree in Nursing PLUS 5 years relevant experience may be considered in lieu of degree.
- Doctoral degree in Nursing is preferred.
- Experience in management of patients across the care continuum preferred.
- Licensed in the state of practice as Advanced Practice Registered Nurse is required.
- Wisconsin Department of Safety and Professional Services (WDSPS) or
- Illinois Department of Financial and Professional Regulation (IDFPR)
- Basic Life Support (BLS) certification is required.
- Board certification from the National Certification Corporation is preferred.
- Controlled Substance license in state of practice is preferred.
- Federal DEA license is preferred.
- Neonatal Resuscitation Program (NRP) certification is preferred.
Throughout communities in Illinois and Wisconsin, 13 hospitals, numerous community-based health centers and clinics, our 13,000+ colleagues have built a culture based on our solid core values of respect, care, competence, and joy. These are the ideals we believe in, work by, and live each day.
Built upon more than 145 years of service to the communities we serve, we now look to the future and our place in it as a healthcare system that strives to continually improve processes, procedures, and outcomes with the latest and most advanced technologies and treatments.
Regardless of how far our passion for excellence carries us, our focus will always remain on the most important person in our entire organization: The patient.
HSHS requires COVID-19 vaccines or an approved medical or religious exemption for all colleagues.
HSHS and affiliates is an Equal Opportunity Employer (EOE).
HSHS is proud to be an equal opportunity workplace dedicated to pursuing and hiring a diverse workforce.
Benefits: HSHS provides a benefits package designed to support the overall well-being of our colleagues including their physical, emotional, financial, spiritual, and work health. Colleagues budgeted to work at least 32 hours per pay period are eligible for HSHS benefits.
- Comprehensive and affordable health coverage includes medical, prescription, dental and vision coverage for full-time and part-time colleagues.
- Retirement benefits including HSHS contributions.
- Education Assistance benefits include up to $5,250 of educational assistance each calendar year and tuition discounts to select colleges with no waiting period
- Adoption Assistance provides financial support up to $7,500 for colleagues growing their families through adoption to reimburse application and legal fees, transportation, and more!
- Other benefits include: Wellness program with incentives, employer-paid life insurance and short-term and long-term disability coverage, flexible spending accounts, employee assistance program, ID theft coverage, colleague rewards and recognition program, discount program, and more!
A successful candidate's actual pay rate will be based on several factors including relevant experience, skills, training, certifications and education.
Notice Regarding Potential Use of Artificial Intelligence in the Hiring Process
Hospital Sisters may use automated tools, including artificial intelligence or machine-learning technologies, to assist with certain administrative aspects of the recruitment process. These tools may help our recruiting team organize applications, search for resumes, identify qualifications reflected in application materials, and facilitate communications or scheduling with applicants.
Information used by these tools may include materials you provide during the application process, such as your resume, work history, education, qualifications, and responses to application questions.
These tools are used only to support our recruiting process. Hiring decisions are made by HSHS personnel, and automated tools do not make employment decisions on behalf of HSHS.
Applicants who have questions about this notice or who require a reasonable accommodation or alternative evaluation method may contact HSHS Human Resources at Contact@hshs.org
See All 44 Practice Assistant Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
Find Practice Assistant JobsPractice Assistant Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Practice Assistant Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Education
- Healthcare & Medical Services
What Illinois Employers Look For
The qualifications that appear most often in practice assistant jobs across Illinois.
- Active Illinois licensure or certification recognized by the Illinois Department of Professional Regulation
- Associate or bachelor's degree in health administration, business, or a related field
- Proficiency in electronic health record systems such as Epic or Cerner
- Minimum one to two years of administrative or clinical support experience
- Strong written and verbal communication skills for patient and provider interaction
- Familiarity with medical billing, coding, or legal documentation processes
Practice Assistant Jobs in Illinois: Frequently Asked Questions
How do you become a practice assistant in Illinois?
Most practice assistant roles in Illinois require at minimum a high school diploma, though an associate degree in medical assisting or healthcare administration gives candidates a strong edge. Clinical practice assistants may need certification through a nationally recognized body, which Illinois employers broadly accept. The Illinois Department of Professional Regulation oversees related allied health credentials. Many candidates also complete coursework in medical terminology, billing, and health records before applying.
Which companies hire practice assistants in Illinois?
Illinois practice assistant roles are posted by Duly Health and Care, OSF HealthCare, and UChicago Medicine and others right now, based on current listings on Migrate Mate as of October 2026. Illinois's dense concentration of hospital networks, specialty clinics, and law firms makes it one of the more active states for this role throughout the year.
Which Illinois cities have the most practice assistant jobs?
Chicago, DeKalb, and Mokena have the most practice assistant openings in Illinois right now. Chicago dominates because of its size and its deep concentration of academic medical centers, large law firms, and corporate headquarters, while Springfield draws demand from state government health agencies and regional hospital systems, and Peoria anchors a strong cluster of multi-specialty medical practices in central Illinois.
Are there remote practice assistant jobs in Illinois?
Yes, but they're rare. Practice assistant work is largely on-site because it involves direct patient interaction, physical records management, and hands-on clinical or office support. About 30% of practice assistant openings tied to Illinois are remote or hybrid as of October 2026, and those positions tend to involve administrative coordination, scheduling, or documentation review rather than direct patient-facing duties.
How can I get hired as a practice assistant in Illinois with little or no experience?
The most realistic entry path is applying to patient service representative or medical receptionist roles at large Illinois health systems like Northwestern Medicine or Advocate Health Care, which regularly hire candidates without prior clinical experience and provide on-the-job training. Completing a medical assisting certificate program at a community college like Oakton College or Triton College also positions candidates well. Lateral moves from administrative assistant or customer service roles are common, and obtaining a basic medical terminology certificate gives entry-level applicants a measurable edge.
Where can I find and apply to practice assistant jobs in Illinois?
You can find and apply to practice assistant jobs in Illinois on Migrate Mate, which lists current Illinois openings across the state. Search the available roles, find the ones that match your experience and preferred location, and apply directly to the ones that fit.
See All 44 Practice Assistant Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
Find Practice Assistant Jobs