Practice Assistant Jobs in Pennsylvania

Practice Assistant jobs in Pennsylvania are concentrated in Philadelphia, Pittsburgh, and Harrisburg, where large health systems, law firms, and academic medical centers drive steady hiring across clinical, legal, and administrative specialties. Employers like Penn Medicine, UPMC, and Jefferson Health maintain consistent openings for practice assistants at every level, from entry-level administrative support roles to experienced clinical or legal practice assistants. Demand is especially strong in healthcare practice management, family law support, and outpatient clinical assistance. Find a role that fits below and apply directly.

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Overview

Open roles39
Top employerWellSpan Health
Top cityPhiladelphia, PA
Cities hiring23
Work type89% On-site
Top industryHealthcare

Showing 5 of 39+ Practice Assistant jobs

Penn State Health
Physician Assistant - Family Practice Harrisburg Region
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Penn State Health
Added 1d ago
Physician Assistant - Family Practice Harrisburg Region
Penn State Health
Mechanicsburg, Pennsylvania
Healthcare Administration
Patient Services & Wellbeing
Physicians
BLS Certification
10,000+

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WellSpan Health
Medical Assistant PRN - MG Family Practice Milton - Days
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WellSpan Health
Added 2d ago
Medical Assistant PRN - MG Family Practice Milton - Days
WellSpan Health
Milton, Pennsylvania
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
BLS Certification
10,000+

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S
Medical Assistant -- Roxborough Family Practice
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S
Added 5d ago
Medical Assistant -- Roxborough Family Practice
Suburban Community Medical Group
East Norriton, Pennsylvania
Healthcare Administration
Patient Services & Wellbeing
Public Health
BLS Certification

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A
Part-Time Nurse Practitioner or Physician Assistant (Independent Practice)
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A
Added 6d ago
Part-Time Nurse Practitioner or Physician Assistant (Independent Practice)
Aspire Urgent Care
Harrisburg, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
$65 - $75/hr
On-Site

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UPMC
Medical Assistant - Chambers Hill Family Practice
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UPMC
Added 1w ago
Medical Assistant - Chambers Hill Family Practice
UPMC
Harrisburg, Pennsylvania
Administrative & Office Support
Executive Assistant & Personal Assistant
Human Resources (HR) — Generalist
$19 - $28.6/hr
CPR Certification
10,000+

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See All 39 Practice Assistant Jobs in Pennsylvania

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Practice Assistant Jobs by City in Pennsylvania

Where Pennsylvania roles are concentrated, by current openings.

Philadelphia
9 jobs
Pittsburgh
3 jobs
York
2 jobs
Glenside
2 jobs
Gettysburg
2 jobs
Harrisburg
2 jobs
Jenkintown
2 jobs
Mechanicsburg
2 jobs
Bath
1 job

Practice Assistant Job Market in Pennsylvania

A snapshot from current Pennsylvania openings, updated as new roles post.

Who's Hiring

WellSpan Health
WellSpan Health7 open roles
UPMC
UPMC5 open roles
Thomas Jefferson University & Jefferson Health
Thomas Jefferson University & Jefferson Health5 open roles

Top Industries Hiring

  • Healthcare & Medical Services
  • Education

What Pennsylvania Employers Look For

The qualifications that appear most often in practice assistant jobs across Pennsylvania.

  • Active Pennsylvania certification or registration relevant to the practice specialty (clinical or administrative)
  • Associate or bachelor's degree in healthcare administration, legal studies, or a related field
  • Proficiency with electronic health records systems such as Epic or Cerner
  • At least one year of experience in a medical, legal, or professional office setting
  • Strong knowledge of HIPAA compliance and patient or client confidentiality standards
  • Demonstrated ability to manage scheduling, billing, and correspondence in a fast-paced practice

Practice Assistant Jobs in Pennsylvania: Frequently Asked Questions

How do you become a practice assistant in Pennsylvania?

The path depends on your specialty. For clinical practice assistant roles, Pennsylvania employers typically require completion of an accredited medical assistant program and national certification through the American Association of Medical Assistants or a comparable body, which Pennsylvania healthcare systems widely recognize. For legal or administrative practice assistant positions, a relevant associate or bachelor's degree is the standard entry point. Some large Pennsylvania health systems and law firms also accept candidates who combine a high school diploma with substantial on-the-job training in a supervised setting.

Which companies hire practice assistants in Pennsylvania?

Pennsylvania practice assistant roles are posted by WellSpan Health, UPMC, and Thomas Jefferson University & Jefferson Health and others right now, based on current listings on Migrate Mate as of August 2026. Pennsylvania's dense concentration of academic medical centers, regional health networks, and large law firms in Philadelphia and Pittsburgh means consistent openings across both clinical and professional practice settings.

Which Pennsylvania cities have the most practice assistant jobs?

Philadelphia, Pittsburgh, and York are the Pennsylvania cities with the most practice assistant openings. Philadelphia leads because of its concentration of academic medical centers, law firms, and insurance companies, while Pittsburgh's strength in healthcare and technology drives demand there, and Harrisburg's role as the state capital supports openings in government-adjacent professional practices and administrative offices.

Are there remote practice assistant jobs in Pennsylvania?

Yes, but they're rare. About 11% of practice assistant openings tied to Pennsylvania are remote or hybrid as of August 2026, reflecting that most of the work is hands-on or front-facing in a clinical or office environment. The portions of the role most likely to appear in remote or hybrid formats are insurance authorization, medical billing, and administrative scheduling for larger Pennsylvania health systems or multi-site legal practices.

How can I get hired as a practice assistant in Pennsylvania with little or no experience?

The most realistic starting point is a medical assistant training program at a Pennsylvania community college, such as Community College of Philadelphia or CCAC, which often lead directly to externship placements with local employers. UPMC and Penn Medicine both run new-graduate and associate programs that bring in candidates with limited experience for supervised clinical or administrative practice roles. Candidates coming from adjacent positions like medical receptionist, patient service representative, or legal secretary have a strong advantage, and obtaining a Certified Medical Administrative Assistant credential before applying noticeably strengthens applications to Pennsylvania health systems.

Where can I find and apply to practice assistant jobs in Pennsylvania?

You can find and apply to practice assistant jobs in Pennsylvania on Migrate Mate, which lists current openings from employers across the state. Search the available roles, find positions that match your experience and location, and apply directly to the ones that fit.

See All 39 Practice Assistant Jobs in Pennsylvania

Find roles in Pennsylvania that match your experience and apply in just a few clicks.

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