Practice Assistant Jobs in Pennsylvania
Practice Assistant jobs in Pennsylvania are concentrated in Philadelphia, Pittsburgh, and Harrisburg, where large health systems, law firms, and academic medical centers drive steady hiring across clinical, legal, and administrative specialties. Employers like Penn Medicine, UPMC, and Jefferson Health maintain consistent openings for practice assistants at every level, from entry-level administrative support roles to experienced clinical or legal practice assistants. Demand is especially strong in healthcare practice management, family law support, and outpatient clinical assistance. Find a role that fits below and apply directly.
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Penn State Health - Penn State Health Medical Group LLC
Location: US:PA:Harrisburg (Colonial Park Family Practice will be the 'home' office)
Work Type: Full Time
FTE: 1.0
Shift: Day
Hours: 40 hours per week
Minimum Hourly Rate: $56.88
Recruiter Contact: Please contact Jill R. Brubaker at jbrubaker@pennstatehealth.psu.edu for additional information
SUMMARY OF POSITION:
We are seeking a compassionate, collaborative, and adaptable Family Medicine Advanced Practice Provider (APP) to join our primary care team as a Float APP. This position provides clinical coverage across multiple family medicine locations in the Harrisburg Metropolitan region, helping maintain access to high-quality care during provider vacations, leaves of absence, staffing needs, and periods of increased patient volume. Because this is a float position, the APP will also support the broader primary care network through inbox management and other clinical administrative responsibilities when direct patient care needs are low.
The ideal candidate is comfortable working with patients across the lifespan, adapting quickly to different practice environments, and partnering effectively with physicians, APPs, nurses, and support staff.
The Advanced Practice Provider follows established nursing standards, procedures, and practices, and gives specific patient care directions to nursing and other staff.
KEY RESPONSIBILITIES:
Provide comprehensive primary care to patients across the lifespan, including preventive, acute, and chronic care. Evaluate, diagnose, and treat common medical conditions within the APP’s scope of practice; perform physical examinations; develop treatment plans; prescribe medications; and manage chronic conditions such as hypertension, diabetes, hyperlipidemia, asthma, and other common primary care diagnoses. Provide preventive services, health counseling, and age-appropriate screenings; order and interpret laboratory and diagnostic studies; and perform or assist with appropriate office-based procedures based on training and credentialing. Adapt efficiently to varying workflows, electronic medical record environments, and clinical teams while coordinating referrals and collaborating with specialists and other members of the care team. Maintain accurate, timely, and compliant medical documentation. During periods when scheduled patient-care needs are limited, provide inbox management support for other family medicine practices and providers within the organization, including reviewing and appropriately addressing patient portal messages, laboratory and diagnostic results, medication refill requests, and other clinical inbox items within the APP’s scope of practice, as well as assisting with results and messages requiring timely clinical follow-up. Support access, continuity, and operational efficiency across the primary care network through other appropriate clinical and administrative responsibilities as assigned.
MINIMUM QUALIFICATION(S):
- Graduate of an AMA approved Physician Assistant Program or baccalaureate or higher degree program that meets licensure requirements in the State of employment
- National Certification in State of employment or in another State with reciprocity and licensure to practice in the State of employment
- Basic Life Support (BLS) certification
PREFERRED QUALIFICATION(S):
Previous experience working in multiple clinical locations or in a float/coverage role. At least 3 years of APP work experience.
WHY PENN STATE HEALTH?
Penn State Health offers exceptional opportunities to learn and grow, exposure to a wide patient population, and the ability to provide individualized, innovative, and specialized care to patients in the community.
Penn State Health offers an exceptional benefits package including medical, dental and vision with no waiting period as well as a Total Rewards Program that highlights a few of the many additional offerings below:
- Be Well with Employee Wellness Programs, and Fitness Discounts (University Fitness Center, Peloton).
- Be Balanced with Generous Paid Time Off, Personal Time, and Paid Parental Leave.
- Be Secured with Retirement, Extended Illness Bank, Life Insurance, and Identity Theft Protection.
- Be Rewarded with Competitive Pay, Tuition Reimbursement, and PAWS UP employee recognition program.
- Be Supported by the HR Solution Center, Learning and Organizational Development and Virtual Benefits Orientation, Employee Exclusive Concierge Service for scheduling.
WHY PENN STATE HEALTH MEDICAL GROUP?
#WeAre committed to providing patient- and family-centered care to all patients —and skillfully handle needs at every level of complexity utilizing our shared governance model of care. The Medical Group is constructed of both primary care and multi-specialty offices that are striving to make a difference in each patient’s healthcare routine. Working alongside seasoned professionals, you will be spearheading the mission of Penn State Health to provide the highest quality care to all patients within their local community! Working with us means being part of a team that strives to provide excellent patient care every day, but also one that works together to set and achieve goals, build on the Penn State Health legacy and create new possibilities for the future.
YOU TAKE CARE OF THEM. WE’LL TAKE CARE OF YOU. State-of-the-art equipment, endless learning, and a culture of excellence – that’s Penn State Health. But what makes our healthcare award-winning? That’s all you.
This job posting is a general outline of duties performed and is not to be misconstrued as encompassing all duties performed within the position. Eligibility for shift differential pay based on the terms outlined in company policy or union contract. All individuals (including current employees) selected for a position will undergo a background check appropriate for the position's responsibilities.
Penn State Health is an Equal Opportunity Employer and does not discriminate on the basis of any protected class including disability or veteran status. Penn State Health’s policies and objectives are in direct compliance with all federal and state constitutional provisions, laws, regulations, guidelines, and executive orders that prohibit or outlaw discrimination.
See All 39 Practice Assistant Jobs in Pennsylvania
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Find Practice Assistant JobsPractice Assistant Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Practice Assistant Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Education
What Pennsylvania Employers Look For
The qualifications that appear most often in practice assistant jobs across Pennsylvania.
- Active Pennsylvania certification or registration relevant to the practice specialty (clinical or administrative)
- Associate or bachelor's degree in healthcare administration, legal studies, or a related field
- Proficiency with electronic health records systems such as Epic or Cerner
- At least one year of experience in a medical, legal, or professional office setting
- Strong knowledge of HIPAA compliance and patient or client confidentiality standards
- Demonstrated ability to manage scheduling, billing, and correspondence in a fast-paced practice
Practice Assistant Jobs in Pennsylvania: Frequently Asked Questions
How do you become a practice assistant in Pennsylvania?
The path depends on your specialty. For clinical practice assistant roles, Pennsylvania employers typically require completion of an accredited medical assistant program and national certification through the American Association of Medical Assistants or a comparable body, which Pennsylvania healthcare systems widely recognize. For legal or administrative practice assistant positions, a relevant associate or bachelor's degree is the standard entry point. Some large Pennsylvania health systems and law firms also accept candidates who combine a high school diploma with substantial on-the-job training in a supervised setting.
Which companies hire practice assistants in Pennsylvania?
Pennsylvania practice assistant roles are posted by WellSpan Health, UPMC, and Thomas Jefferson University & Jefferson Health and others right now, based on current listings on Migrate Mate as of August 2026. Pennsylvania's dense concentration of academic medical centers, regional health networks, and large law firms in Philadelphia and Pittsburgh means consistent openings across both clinical and professional practice settings.
Which Pennsylvania cities have the most practice assistant jobs?
Philadelphia, Pittsburgh, and York are the Pennsylvania cities with the most practice assistant openings. Philadelphia leads because of its concentration of academic medical centers, law firms, and insurance companies, while Pittsburgh's strength in healthcare and technology drives demand there, and Harrisburg's role as the state capital supports openings in government-adjacent professional practices and administrative offices.
Are there remote practice assistant jobs in Pennsylvania?
Yes, but they're rare. About 11% of practice assistant openings tied to Pennsylvania are remote or hybrid as of August 2026, reflecting that most of the work is hands-on or front-facing in a clinical or office environment. The portions of the role most likely to appear in remote or hybrid formats are insurance authorization, medical billing, and administrative scheduling for larger Pennsylvania health systems or multi-site legal practices.
How can I get hired as a practice assistant in Pennsylvania with little or no experience?
The most realistic starting point is a medical assistant training program at a Pennsylvania community college, such as Community College of Philadelphia or CCAC, which often lead directly to externship placements with local employers. UPMC and Penn Medicine both run new-graduate and associate programs that bring in candidates with limited experience for supervised clinical or administrative practice roles. Candidates coming from adjacent positions like medical receptionist, patient service representative, or legal secretary have a strong advantage, and obtaining a Certified Medical Administrative Assistant credential before applying noticeably strengthens applications to Pennsylvania health systems.
Where can I find and apply to practice assistant jobs in Pennsylvania?
You can find and apply to practice assistant jobs in Pennsylvania on Migrate Mate, which lists current openings from employers across the state. Search the available roles, find positions that match your experience and location, and apply directly to the ones that fit.
See All 39 Practice Assistant Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
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