Advanced Practice Provider Jobs in Missouri
Advanced Practice Provider jobs in Missouri are concentrated in hospital systems, integrated health networks, and outpatient specialty clinics, with the market consistently active for nurse practitioners, physician assistants, and certified nurse midwives at both entry and experienced levels. The largest concentrations of openings are in Kansas City, St. Louis, and Springfield, where employers such as BJC HealthCare, Saint Luke's Health System, and Mercy Health maintain a steady need for advanced practice providers. Primary care, urgent care, and behavioral health are the most in-demand specialties statewide. Scan the live roles below and apply to whichever ones fit.
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Children’s Mercy is in the heart of Kansas City – a metro abounding in cultural experiences, vibrant communities and thriving businesses. This is where our patients and families live, work and play. This is a community that has embraced our hospital and we strive to say thanks by giving back. As a leader in children’s health, we engage in meaningful programs and partnerships throughout the region so that we can improve the lives of children beyond the walls of our hospital.
As one of the top-ranked kidney care programs in the nation, the Division of Pediatric Nephrology at Children’s Mercy provides family-centered care for children and teens with kidney diseases.
Proficiently provides comprehensive, evidence-based advanced practice nursing care based on the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement for patient populations.
The APP provides outpatient nephrology care for children with a variety of kidney diagnoses in the outpatient nephrology clinic and via telehealth encounters.
Diagnoses include, but are not limited to, enuresis, hypertension, genetic kidney disorders, glomerulonephritis, chronic kidney disease, stages I-IV, congenital anomalies, and dysplasia.
Advanced Practice Registered Nurses II (APRN-II) provides proficient, comprehensive, evidence-based advanced practice nursing to address the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement. An APRN II obtains a comprehensive health history; performs physical examination; formulates a plan of care and treatment; prescribes/performs diagnostic and therapeutic interventions and procedures; and participates in patient and family education. Each APRN-II demonstrates professional leadership and participates in evidenced-based practice, quality improvement, and/or research activities, and organizational development.
At Children’s Mercy, we are committed to ensuring that everyone feels welcomed within our walls. A successful candidate for this position will join us as we strive to create a workplace that reflects the community we serve, as well as our core values of kindness, curiosity, inclusion, team and integrity.
Additionally, it’s important to us that we remain transparent with all potential job candidates. Because we value the safety of the patients and families we serve, as well as the Children’s Mercy staff, we want to let you know that the seasonal influenza vaccine is a condition of employment for all employees in our organization. New employees must be willing to be vaccinated if found non-immune to measles, mumps, rubella (MMR) and chicken pox (varicella) and/or without evidence of tetanus, diphtheria, acellular pertussis (Tdap) vaccination since 2005. If you are selected for this position, you will be asked to supply your immunization records as proof of vaccination. If you and have any concerns about receiving these vaccines, medical and/or religious exemptions can be further discussed with Human Resources.
- Master's Degree and 1-2 years experience 1-2 years pediatric APRN experience with Masters. Exceptions considered on a case-by-case basis within preferred specialty. or
- Doctorate in Nursing Practice (DNP) - preferred and 1-2 years experience 1 year pediatric APRN experience. Exceptions considered on a case-by-case basis within preferred specialty.
- Licensed RN - Kansas, Registered Nurse Multistate License Kansas required upon hire
- Licensed RN - MO, Registered Nurse Multistate License Missouri required upon hire
- RN Compact license for all states besides KS and MO
- APRN board certification congruent with population and practice setting (see policy statement: Advanced Practice Registered Nurse Roles and Practice Setting) Required Upon Hire
- Successful completion of national board certification in one of the following:
- Certified Nurse Practitioner (CNP) in MO & KS Required Upon Hire
- Refer to Nursing and Advanced Practice Provider Licensure and Certification policy for required Life Support Certifications Required Upon Hire
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PNP-Primary Care will be required
- candidate will have two years to enroll/be accepted in a program and five years to complete the program
- Specialty Certification relevant to unit’s patient population (determined by Nurse Manager/Director) Preferred
CM is committed to creating a workforce that supports the diverse backgrounds of our patients and families. We know that our greatest strengths come from the people who make up our team, so we hire great people from a wide variety of backgrounds, not just because it’s the right thing to do, but because it makes our hospital stronger and our patient care more compassionate.
If you share our values and our enthusiasm for service, you will find a home at CM. In recruiting for our team, we welcome the unique contributions that you can bring, including education, ideas, culture, and beliefs.
See All 42 Advanced Practice Provider Jobs in Missouri
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Find JobsAdvanced Practice Provider Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Advanced Practice Provider Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- SSM Health16

- Children's Mercy Hospitals & Clinics8

- BJC HealthCare5

- Saint Luke's3

- ChenMed1

Top Industries Hiring
- Healthcare & Medical Services
- Education
What Missouri Employers Look For
The qualifications that appear most often in advanced practice provider jobs across Missouri.
- Active Missouri advanced practice registered nurse or physician assistant license required
- Master's or doctoral degree in a relevant advanced practice nursing or physician assistant program
- National board certification such as AANP, ANCC, or NCCPA appropriate to the specialty
- Current DEA registration and Missouri collaborative practice agreement where required by law
- Minimum one to three years of clinical experience in a relevant specialty or patient population
- Current BLS and ACLS certifications required prior to clinical start date
Advanced Practice Provider Jobs in Missouri: Frequently Asked Questions
How do you become a advanced practice provider in Missouri?
To practice as an advanced practice provider in Missouri, you must obtain licensure through the Missouri State Board of Nursing for nurse practitioners and certified nurse midwives, or through the Missouri State Board of Registration for the Healing Arts for physician assistants. This requires completing an accredited graduate program, passing the applicable national board certification exam, and meeting any collaborative practice or prescriptive authority requirements set by Missouri law before you begin seeing patients.
How much do advanced practice providers make in Missouri?
Advanced practice providers in Missouri earn a median of about $129,930 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $100,650 for the lowest 10% to over $162,060 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire advanced practice providers in Missouri?
Employers hiring advanced practice providers in Missouri right now include SSM Health, Children's Mercy Hospitals & Clinics, and BJC HealthCare, based on current listings on Migrate Mate as of August 2026. Missouri's large integrated health systems and regional medical centers drive the bulk of consistent demand, particularly for primary care and specialty-focused roles across urban and rural sites.
Which Missouri cities have the most advanced practice provider jobs?
The Missouri cities with the most advanced practice provider openings are St. Louis, Kansas City, and St Louis. Kansas City and St. Louis lead because of their dense concentration of major hospital systems, academic medical centers, and multispecialty group practices, while Springfield anchors a large regional health corridor that serves southwest Missouri and supports consistent advanced practice hiring through Mercy and CoxHealth.
Are there remote advanced practice provider jobs in Missouri?
Yes, but they're rare. Advanced practice provider work is primarily hands-on and clinic-based, limiting fully remote options. About 60% of advanced practice provider openings tied to Missouri are remote or hybrid as of August 2026, and those tend to be telehealth roles in behavioral health, psychiatry, or chronic disease management where patient consultations can be conducted virtually.
How can I get hired as a advanced practice provider in Missouri with little or no experience?
The most realistic entry path is applying to new-graduate or transitional programs at Missouri's large health systems, including BJC HealthCare's new-grad NP onboarding tracks and Mercy's residency-style advanced practice programs designed for candidates with limited post-graduate experience. Roles in urgent care, primary care float pools, and hospitalist support often require less specialty experience than acute care positions. Securing your Missouri collaborative practice agreement early and completing any required DEA registration before applying strengthens your candidacy considerably.
Where can I find and apply to advanced practice provider jobs in Missouri?
You can find and apply to advanced practice provider jobs in Missouri on Migrate Mate, which lists current Missouri openings across health systems, clinics, and specialty practices statewide. Search the available roles, identify the ones that match your license type, specialty, and preferred location, and apply directly to whichever positions fit your background.
See All 42 Advanced Practice Provider Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
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