Advanced Practice Provider Jobs in Missouri

Advanced Practice Provider jobs in Missouri are concentrated in hospital systems, integrated health networks, and outpatient specialty clinics, with the market consistently active for nurse practitioners, physician assistants, and certified nurse midwives at both entry and experienced levels. The largest concentrations of openings are in Kansas City, St. Louis, and Springfield, where employers such as BJC HealthCare, Saint Luke's Health System, and Mercy Health maintain a steady need for advanced practice providers. Primary care, urgent care, and behavioral health are the most in-demand specialties statewide. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles50
Top employerSSM Health
Top citySt. Louis, MO
Cities hiring18
Work type88% On-site
Top industryHealthcare

Showing 5 of 50+ Advanced Practice Provider jobs

Advanced Practice Provider
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Added 3d ago
Advanced Practice Provider
Saint Luke's
Kansas City, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
10,000+

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Advanced Practice Provider - Nurse Practitioner or Physician Assistant
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Added 4d ago
Advanced Practice Provider - Nurse Practitioner or Physician Assistant
Shriners Children's
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
PALS Certification
5,001-10,000

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Advanced Practice Provider - APP - Vascular Surgery
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Added 5d ago
Advanced Practice Provider - APP - Vascular Surgery
SSM Health
Bridgeton, Missouri
Caregiving & Elderly Support
Healthcare Administration
Patient Services & Wellbeing
10,000+

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Advanced Practice Provider - APP - Complex Care Clinic
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Added 6d ago
Advanced Practice Provider - APP - Complex Care Clinic
SSM Health
Bridgeton, Missouri
Allied Health
Healthcare Administration
Nursing
Master's degree in nursing
10,000+

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Advanced Practice Provider - APP - Cardiac Electrophysiology
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Added 6d ago
Advanced Practice Provider - APP - Cardiac Electrophysiology
SSM Health
Saint Charles, Missouri
Allied Health
Healthcare Administration
Nursing
10,000+

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Advanced Practice Provider Jobs by City in Missouri

Where Missouri roles are concentrated, by current openings.

St. Louis
16 jobs
Kansas City
10 jobs
Clinton
3 jobs
Bridgeton
3 jobs
Saint Charles
3 jobs
Fenton
2 jobs
Richmond Heights
2 jobs
Belton
1 job
Warsaw
1 job

Advanced Practice Provider Job Market in Missouri

A snapshot from current Missouri openings, updated as new roles post.

Who's Hiring

  • SSM Health19
  • BJC HealthCare7
  • Saint Luke's6
  • Golden Valley Memorial Healthcare4
  • Children's Mercy Hospitals & Clinics4

Top Industries Hiring

  • Healthcare & Medical Services

What Missouri Employers Look For

The qualifications that appear most often in advanced practice provider jobs across Missouri.

  • Active Missouri advanced practice registered nurse or physician assistant license required
  • Master's or doctoral degree in a relevant advanced practice nursing or physician assistant program
  • National board certification such as AANP, ANCC, or NCCPA appropriate to the specialty
  • Current DEA registration and Missouri collaborative practice agreement where required by law
  • Minimum one to three years of clinical experience in a relevant specialty or patient population
  • Current BLS and ACLS certifications required prior to clinical start date

Advanced Practice Provider Jobs in Missouri: Frequently Asked Questions

How do you become a advanced practice provider in Missouri?

To practice as an advanced practice provider in Missouri, you must obtain licensure through the Missouri State Board of Nursing for nurse practitioners and certified nurse midwives, or through the Missouri State Board of Registration for the Healing Arts for physician assistants. This requires completing an accredited graduate program, passing the applicable national board certification exam, and meeting any collaborative practice or prescriptive authority requirements set by Missouri law before you begin seeing patients.

How much do advanced practice providers make in Missouri?

Advanced practice providers in Missouri earn a median of about $129,930 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $100,650 for the lowest 10% to over $162,060 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire advanced practice providers in Missouri?

Employers hiring advanced practice providers in Missouri right now include SSM Health, BJC HealthCare, and Saint Luke's, based on current listings on Migrate Mate as of October 2026. Missouri's large integrated health systems and regional medical centers drive the bulk of consistent demand, particularly for primary care and specialty-focused roles across urban and rural sites.

Which Missouri cities have the most advanced practice provider jobs?

The Missouri cities with the most advanced practice provider openings are St. Louis, Kansas City, and Clinton. Kansas City and St. Louis lead because of their dense concentration of major hospital systems, academic medical centers, and multispecialty group practices, while Springfield anchors a large regional health corridor that serves southwest Missouri and supports consistent advanced practice hiring through Mercy and CoxHealth.

Are there remote advanced practice provider jobs in Missouri?

Yes, but they're rare. Advanced practice provider work is primarily hands-on and clinic-based, limiting fully remote options. About 13% of advanced practice provider openings tied to Missouri are remote or hybrid as of October 2026, and those tend to be telehealth roles in behavioral health, psychiatry, or chronic disease management where patient consultations can be conducted virtually.

How can I get hired as a advanced practice provider in Missouri with little or no experience?

The most realistic entry path is applying to new-graduate or transitional programs at Missouri's large health systems, including BJC HealthCare's new-grad NP onboarding tracks and Mercy's residency-style advanced practice programs designed for candidates with limited post-graduate experience. Roles in urgent care, primary care float pools, and hospitalist support often require less specialty experience than acute care positions. Securing your Missouri collaborative practice agreement early and completing any required DEA registration before applying strengthens your candidacy considerably.

Where can I find and apply to advanced practice provider jobs in Missouri?

You can find and apply to advanced practice provider jobs in Missouri on Migrate Mate, which lists current Missouri openings across health systems, clinics, and specialty practices statewide. Search the available roles, identify the ones that match your license type, specialty, and preferred location, and apply directly to whichever positions fit your background.

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