RN Staff Nurse Jobs in Pennsylvania

RN Staff Nurse jobs in Pennsylvania are among the most consistently active in the region, with strong demand running from new graduate positions through experienced senior staff roles in acute care, long-term care, and outpatient settings. The heaviest hiring is centered in Philadelphia, Pittsburgh, and Allentown, where large systems such as Penn Medicine, UPMC, and St. Luke's University Health Network maintain ongoing needs. Medical-surgical, critical care, and behavioral health are the specialties drawing the most consistent openings across the state. Find a role that fits below and apply directly.

Find RN Staff Nurse Jobs

Overview

Open roles54
Top employerUPMC
Top cityAltoona, PA
Cities hiring19
Work type100% On-site
Top industryHealthcare

Showing 5 of 54+ RN Staff Nurse jobs

UPMC
Professional Staff Nurse (RN), FT Flex Nights - ED (Hanover)
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UPMC
New 12h ago
Professional Staff Nurse (RN), FT Flex Nights - ED (Hanover)
UPMC
Hanover, Pennsylvania
Business Operations
Customer Service
Customer Success
$38.96 - $51.73/hr
PALS Certification
10,000+

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UPMC
Professional Staff Nurse (RN), Days w/rotation - med/surg E4 (Hanover)
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UPMC
New 16h ago
Professional Staff Nurse (RN), Days w/rotation - med/surg E4 (Hanover)
UPMC
Hanover, Pennsylvania
Clinical Support
Healthcare Administration
Human Resources
Nursing
$38.96 - $51.73/hr
BLS Certification
10,000+

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UPMC
Professional Staff Nurse, ONC (RN) - Medical Oncology/Infusion
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UPMC
Added 1d ago
Professional Staff Nurse, ONC (RN) - Medical Oncology/Infusion
UPMC
Erie, Pennsylvania
Business Operations
Customer Service
Customer Success
$36.5 - $45.04/hr
Bachelor of Science in Nursing
10,000+

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UPMC
Professional Staff Nurse, ONC (RN) - Medical Oncology/Infusion
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UPMC
Added 1d ago
Professional Staff Nurse, ONC (RN) - Medical Oncology/Infusion
UPMC
Farrell, Pennsylvania
Business Operations
Customer Service
Customer Success
$36.5 - $45.04/hr
Bachelor of Science in Nursing
10,000+

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UPMC
Professional Staff Nurse (RN) - L&D (Hanover)
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UPMC
Added 1d ago
Professional Staff Nurse (RN) - L&D (Hanover)
UPMC
Hanover, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
$38.96 - $51.73/hr
PALS Certification
10,000+

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See All 54 RN Staff Nurse Jobs in Pennsylvania

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RN Staff Nurse Jobs by City in Pennsylvania

Where Pennsylvania roles are concentrated, by current openings.

Altoona
12 jobs
Hanover
6 jobs
Hershey
4 jobs
Pittsburgh
3 jobs
Carlisle
2 jobs
Lancaster
2 jobs
Greensburg
2 jobs
Erie
1 job

RN Staff Nurse Job Market in Pennsylvania

A snapshot from current Pennsylvania openings, updated as new roles post.

Who's Hiring

  • UPMC
    UPMC30
  • Temple University Health System
    Temple University Health System12
  • Penn State Health
    Penn State Health4
  • Penn Medicine
    Penn Medicine2
  • CO-MHAR
    CO-MHAR1

Top Industries Hiring

  • Healthcare & Medical Services20
  • Education3
  • Science & Research2

What Pennsylvania Employers Look For

The qualifications that appear most often in RN staff nurse jobs across Pennsylvania.

  • Active RN license issued or recognized by the Pennsylvania State Board of Nursing
  • Associate degree in nursing required with bachelor's degree in nursing preferred
  • Current BLS certification required with ACLS preferred for critical care units
  • Minimum one year of acute care or med-surg clinical experience in many postings
  • Demonstrated ability to manage a patient load independently with minimal supervision
  • Proficiency with electronic health record systems such as Epic or Cerner

RN Staff Nurse Jobs in Pennsylvania: Frequently Asked Questions

How do you become a rn staff nurse in Pennsylvania?

To work as an rn staff nurse in Pennsylvania, you must hold an active RN license issued by the Pennsylvania State Board of Nursing. You earn that license by completing an accredited associate or bachelor's degree in nursing, then passing the NCLEX-RN exam. Pennsylvania also participates in the Nurse Licensure Compact, so nurses already licensed in a compact state can practice in Pennsylvania without obtaining a separate state license.

How much do RN staff nurses make in Pennsylvania?

RN staff nurses in Pennsylvania earn a median of about $96,430 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $70,800 for the lowest 10% to over $117,900 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire rn staff nurses in Pennsylvania?

Employers hiring rn staff nurses in Pennsylvania right now include UPMC, Temple University Health System, and Penn State Health, based on current listings on Migrate Mate as of August 2026. Pennsylvania's concentration of large academic medical centers and regional health systems means openings appear consistently year-round rather than in seasonal waves.

Which Pennsylvania cities have the most rn staff nurse jobs?

Altoona, Philadelphia, and Hanover lead Pennsylvania for rn staff nurse openings. Philadelphia anchors demand through its dense cluster of academic medical centers and specialty hospitals, Pittsburgh contributes heavily through UPMC's sprawling regional network, and mid-sized markets like Allentown carry strong volume because large community health systems there serve a broad surrounding population.

Are there remote rn staff nurse jobs in Pennsylvania?

Yes, but they're rare. Bedside nursing is an inherently hands-on role, so the overwhelming majority of rn staff nurse positions require in-person work. About 0% of rn staff nurse openings tied to Pennsylvania are remote or hybrid as of August 2026, and those tend to be in utilization review, telephonic case management, or nurse advice line roles rather than direct patient care.

How can I get hired as a rn staff nurse in Pennsylvania with little or no experience?

The most realistic entry path is a new-graduate residency program, and Pennsylvania's largest systems run structured ones specifically for nurses without acute care experience. UPMC, Penn Medicine, and Jefferson Health each operate multi-month residency tracks that rotate new grads through clinical units before placing them in staff positions. Candidates who hold a Pennsylvania RN license, an active BLS certification, and clinical hours from a Pennsylvania-accredited nursing program are consistently prioritized. Applying to med-surg or telemetry units first, rather than specialty units, gives new graduates the strongest footing.

Where can I find and apply to rn staff nurse jobs in Pennsylvania?

You can find and apply to rn staff nurse jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings across health systems, outpatient practices, and long-term care facilities. Find roles that match your credentials and preferred location, then apply directly to the employers posting them.

See All 54 RN Staff Nurse Jobs in Pennsylvania

Find roles in Pennsylvania that match your experience and apply in just a few clicks.

Find RN Staff Nurse Jobs