Internal Medicine Nurse Practitioner Jobs in South Carolina
Internal Medicine Nurse Practitioner jobs in South Carolina are open across Charleston, Columbia, and Florence and other South Carolina metros, with employers like Medical University of South Carolina and Ethos Veterinary Health hiring at every experience level. Find a role that fits below and apply directly.
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INTRODUCTION
MUSC Health is seeking a full-time BC/BE Family Medicine or Internal Medicine physician to join MUSC Health Primary Care - Bamberg. This is an opportunity for an innovative primary care physician to build a rewarding career within a well-known academic health system while also positively impacting rural healthcare access within our state.
ENTITY
MUSC Community Physicians (MCP)
WORKER TYPE
Employee
WORKER SUB-TYPE
Regular
COST CENTER
CC004915 MCP - Orangeburg Primary Care Bamberg
PAY RATE TYPE
Hourly, Salary
PAY GRADE
Health-02
SCHEDULED WEEKLY HOURS
40
WORK SHIFT
JOB DESCRIPTION
MUSC Health is seeking a full-time BC/BE Family Medicine or Internal Medicine physician to join MUSC Health Primary Care - Bamberg. This is an opportunity for an innovative primary care physician to build a rewarding career within a well-known academic health system while also positively impacting rural healthcare access within our state.
Primary Care is essential to MUSC Health’s mission of providing exceptional and accessible treatment to patients in South Carolina. That’s why we’re committed to supporting our primary care physicians with ongoing education, mentorship, and leadership development to help them thrive. Whether you’re passionate about community medicine, shaping the next generation of healthcare leaders, or advancing primary care innovation, MUSC Health can provide the resources and support to help you achieve your goals.
REQUIRED QUALIFICATIONS:
- Candidates must be BE/BC in Family or Internal Medicine
- Unrestricted SC licensure
- Federal and state-controlled substance registration
POSITION HIGHLIGHTS:
- Monday-Thursday 8am-12pm and 1pm-5pm; Friday 8am-12pm
- 20-25 patients per day, on average
- Team includes 2 experienced Physician Assistants and dedicated support staff
- Ideal candidates will have an interest in supporting a diverse patient demographic and enjoy working with experienced Advanced Practice Providers
BENEFITS & RESOURCES FOR PHYSICIANS:
- Competitive compensation and benefits
- Employer-funded retirement plans
- Paid occurrence malpractice coverage
- Paid parental leave
- CME allowance + paid days off
- Public Service Loan Forgiveness (PSLF) eligibility
- One-on-one support services for managing student debt
- Epic EHR with physician-centered optimization and robust user support
- AI-enabled documentation and workflow tools integrated into Epic to reduce administrative burden and support clinical decision-making at the point of care
- Team-based care models that support sustainable workloads, shared responsibility, and physician well-being
LIFE IN BAMBERG, SC:
Located at the intersection of Highways 301, 601, and 78, Bamberg offers small-town charm with easy access to Charleston, Columbia, and Augusta - all just about an hour drive away. The area features a low cost of living, excellent public schools that consistently rank among the top in the state, and strong community investment in education and recreation. With mild winters, warm summers, and well-maintained parks and sports facilities like the Ness Sports Complex, Bamberg provides a welcoming environment for both families and individuals. Physicians will also appreciate the convenience of nearby Amtrak service, regional airports for private travel, and a close-knit community that values quality of life.
ADDITIONAL JOB DESCRIPTION
ABOUT MUSC:
South Carolina’s leading academic health system, MUSC Health serves patients across the state through a growing network of hospitals, clinics, and specialty services. As the clinical enterprise of the Medical University of South Carolina, MUSC Health integrates academic medicine, research, and education with a strong commitment to patient care. Physicians who join MUSC Health become part of a mission-driven organization recognized for clinical excellence, innovation, and meaningful investment in physicians’ success. With opportunities in both academic and community settings, MUSC Health provides the scale, resources, and infrastructure to support meaningful, long-term physician careers.
If you like working with energetic enthusiastic individuals, you will enjoy your career with us!
The Medical University of South Carolina is an Equal Opportunity Employer. MUSC does not discriminate on the basis of race, color, religion or belief, age, sex, national origin, gender identity, sexual orientation, disability, protected veteran status, family or parental status, or any other status protected by state laws and/or federal regulations. All qualified applicants are encouraged to apply and will receive consideration for employment based upon applicable qualifications, merit and business need.
Medical University of South Carolina participates in the federal E-Verify program to confirm the identity and employment authorization of all newly hired employees. For further information about the E-Verify program, please click here: http://www.uscis.gov/e-verify/employees
See All 16 Internal Medicine Nurse Practitioner Jobs in South Carolina
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Find JobsInternal Medicine Nurse Practitioner Jobs by City in South Carolina
Where South Carolina roles are concentrated, by current openings.
Internal Medicine Nurse Practitioner Job Market in South Carolina
A snapshot from current South Carolina openings, updated as new roles post.
Who's Hiring
- Medical University of South Carolina14

- Ethos Veterinary Health2

Top Industries Hiring
- Education12
- Healthcare & Medical Services3
- Animal Care & Pet Services1
What South Carolina Employers Look For
The qualifications that appear most often in internal medicine nurse practitioner jobs across South Carolina.
- Active APRN license with adult or family nurse practitioner board certification (ANCC or AANP)
- Master of Science in Nursing or Doctor of Nursing Practice degree from an accredited program
- DEA registration and state prescriptive authority for controlled substances
- Minimum one to three years of clinical experience in internal medicine or primary care
- Proficiency with electronic health record systems such as Epic, Cerner, or Meditech
- Basic Life Support and Advanced Cardiovascular Life Support certification
Internal Medicine Nurse Practitioner Jobs in South Carolina: Frequently Asked Questions
How many internal medicine nurse practitioner jobs are there in South Carolina?
There are 16+ internal medicine nurse practitioner openings in South Carolina on Migrate Mate as of June 2026, with the most roles in Charleston, Columbia, and Florence. New positions post regularly as employers across South Carolina hire.
How much do internal medicine nurse practitioners make in South Carolina?
Internal medicine nurse practitioners in South Carolina earn a median of about $123,290 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $97,080 for the lowest 10% to over $160,170 for the top 10%. Pay rises with experience, specialty, and employer.
Which South Carolina cities have the most internal medicine nurse practitioner jobs?
Charleston, Columbia, and Florence have the most internal medicine nurse practitioner openings in South Carolina right now, with additional roles spread across smaller metros statewide.
Which companies hire internal medicine nurse practitioners in South Carolina?
Employers hiring internal medicine nurse practitioners in South Carolina include Medical University of South Carolina and Ethos Veterinary Health, based on current listings on Migrate Mate as of June 2026.
Are there remote internal medicine nurse practitioner jobs in South Carolina?
Yes. About 0% of internal medicine nurse practitioner openings tied to South Carolina are remote or hybrid as of June 2026. The rest are on-site roles based in South Carolina metros.
How do I apply for internal medicine nurse practitioner jobs in South Carolina?
You can apply to internal medicine nurse practitioner jobs in South Carolina directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred South Carolina location, then apply to each one that fits.
See All 16 Internal Medicine Nurse Practitioner Jobs in South Carolina
Find roles in South Carolina that match your experience and apply in just a few clicks.
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