Senior Level Lead R&D Engineer Jobs
Senior level lead r&d engineer jobs place seasoned engineers at the helm of research programs, owning technical direction, driving innovation roadmaps, and guiding the cross-functional teams that bring new products to life. Openings are concentrated across Technology & Software, Electronics & Hardware, and Manufacturing, with a mix of on-site, remote, and hybrid settings, and employers like Riot Games, ABB, and Keysight Technologies hiring at this level now.
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Job Title: Principal R&D Scientist
Reports to: Chief Technology officer
FLSA Status: Full time, Regular, Salary, Exempt
About us
At Dimer Instruments we’re creating the next generation of laboratory analytical instruments for the pharmaceutical market. Our products use multiple light-based spectroscopic methods to interrogate solutions containing molecules and particles, providing researchers not just with data but with organized information allowing them to make informed decisions. At Dimer you’ll be working with a high-quality, high-performing, highly collaborative, and enjoyable team of Engineers and Scientists to create products that make a difference in the world. We have fun while we’re creating great products.
Summary
The Principal Research and Development Scientist will be a critical member of the team designing and developing Analytical instruments. They will be expert in the use of optics, optical breadboarding, and optical systems, and in addition to optics they will use a combination of science, math, analysis, scripting/programming, mechanics, data acquisition, and electronics to contribute hands-on through all phases of research and development, including 1) initial math, analysis, simulation, 2) measurement system design, 3) building real-world prototypes that demonstrate proof of concept for individual measurement modalities and functionality, 4) building system prototypes, 5) bringing products from R&D into Manufacturing, 6) demonstrating product performance at every stage in the product lifecycle, and 7) supporting product release and early rapid product improvement. The Principal R&D Scientist will collaborate closely with Mechanical, Electrical, and Software Engineers, and with in-house Application Scientists. The successful Principal R&D Scientist will be able to be scientifically careful and rigorous, able to theoretically understand and experimentally tease apart subtle contributors to data and signals, and also be action-oriented and able to come to quick, practical, and manufacturable solutions. They will be designing and creating scientific instruments that provide cutting edge data and yet are robust in the real world, able to ship to Japan or Europe without optics mis-aligning, and able to reliably operate in sometimes non-ideal laboratory conditions. The successful Principal R&D Scientist will not shy away from tackling the sometimes less glamorous work of contributing to work instructions and assembly instructions (e.g. for an optical alignment or calibration method to be used in manufacturing), generating and documenting manufacturing tools (which can sometimes be complicated analytical instruments in their own right), contributing to user documentation, and running and analyzing user samples. The successful R&D Principal scientist will be highly collaborative, both with Dimer staff across the organization and with external researchers. The Principal R&D Scientist will also be willing and able to educate customers, internal Dimer staff, and other stakeholders regarding the science behind the Dimer products, generating presentations and demonstrations and presenting at conferences, trade shows, customer sites, and for internal training as needed. Dimer Instruments products are scientific instruments and analytical tools used by scientists. The Principal R&D Scientist will be a key member of a collaborative team inventing, designing, developing, and launching products that solve real world challenges and improve the pace of science and pharmaceutical development.
Essential Duties and Responsibilities
- Design, build, and demonstrate performance of optical measurement systems, including imaging and non-imaging systems from UV into the NIR
- Use standard optical and measurement tools to assess performance of optical components including single mode and multi-mode optical fibers, lens, filters, mirrors, optomechanical and assemblies
- Math, simulation, and analysis to predict real world performance of physical systems, e.g. noise floor for a particular optical measurement, cooling rate of a thermoelectric module assembly, signal strength from molecules in solution being probed by various modalities, etc., etc.
- Electronics troubleshooting, including op-amp circuits associated with laser drive, photocurrent measurement, and similar, and digital circuits associated with GPIO, system control, and similar
- Contribute to system level architecture and design of laboratory analytical instrument products
- Demonstrate proof of concept performance of physical systems by designing, building, and demonstrating using prototype systems
- Contribute to DFMEA and generate mitigations for the higher impact failures identified
- Programming and scripting to automate measurements or manufacturing steps, e.g. calibration of a component as a function of temperature
- Perform research and analysis demonstrating the scientific added value of Dimer products by collaborating with industry pharmaceutical researchers, and/or conceiving of novel demonstration measurements
- Contribute to project and product planning, including schedule and budgets, and contribute to project and product reports and updates
- Generate Manufacturing procedures and documentation as needed
- Generate User facing procedures and documentation as needed
- Create and present internally and externally intro level explanations of the science and technology that power Dimer Instruments products
- Scientific publications and presentations
- Contribute to patent applications
- Other tasks as assigned by your supervisor
Qualifications
- Ph.D. in Physics, EE, MechE, ChemE, or equivalent training, work experience, and skills
- Expert in the design and use of optical systems. Strong knowledge of high level math, programming/scripting, data acquisition, electronics, general science
- Demonstrated ability to create and work with real world measurement systems.
Additional Skills
Must have the social “soft skills” required to be collaborative across the organization. Socially adept, able to navigate different groups and functions with competing needs, and able to work with stakeholders to create solutions requiring compromise. Must be able to understand and communicate well in English, both spoken and written, and be able to write reports, work instructions, business correspondence, procedures, and manuals. Must be able to present work in an organized way both for project/progress reviews and design reviews.
Physical Requirements
When working in machine shop, chemistry, or optics lab, appropriate protective gear must be worn including eyewear, eye protection from laser or UV light, lab coats, and closed toed shoes.
Work Environment
Office space, optics lab, chemistry lab, warehouse, and electronics and optical manufacturing space. The employee may occasionally be exposed to moderate noise levels, e.g. from loud fans in electronics equipment. Travel may occasionally be required, e.g. to test labs, customer sites, for conferences and trade shows, or for training.
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- Riot Games11

- ABB3

- Keysight Technologies3

- Hewlett Packard Enterprise | HPE3

- Nokia2

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Senior Level Lead R&D Engineer Jobs: Frequently Asked Questions
How do I get a senior level lead r&d engineer job?
Employers at this level look for engineers who have already led significant R&D projects from concept through commercialization, not just contributed to them. Demonstrating a portfolio of patented innovations, published research, or shipped products carries real weight. Equally important is showing you can mentor junior engineers, align research priorities with business goals, and communicate technical tradeoffs to executive stakeholders.
Which companies hire senior level lead r&d engineers?
Companies hiring senior level lead r&d engineers right now include Riot Games, ABB, and Keysight Technologies, based on current listings on Migrate Mate as of November 2026. Hiring at this level tends to come from established technology, medical device, aerospace, and industrial manufacturers with active product development pipelines and dedicated R&D divisions.
Are there remote senior level lead r&d engineer jobs?
Yes, though availability depends heavily on the nature of the work. About 22% of senior level lead r&d engineer openings are remote or hybrid as of November 2026, with hybrid arrangements being most common since hands-on lab work, prototype testing, and cross-team collaboration often require periodic on-site presence at senior leadership levels.
What makes a lead r&d engineer role senior level?
Senior level lead r&d engineer roles are defined by ownership over entire research programs rather than individual workstreams. Expectations include setting the technical vision for a product line, making architectural decisions with long-term consequences, mentoring mid-level and junior engineers, and influencing R&D investment strategy. The scope is strategic as well as technical, with accountability for outcomes across the full development lifecycle.
Which industries hire the most senior level lead r&d engineers?
Senior Level lead r&d engineer roles concentrate in Technology & Software, Electronics & Hardware, and Manufacturing, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because they sustain large-scale product innovation programs that require experienced engineers capable of leading complex, multi-year research initiatives from early-stage discovery through production readiness.