Machine Learning Engineer Jobs in San Mateo, CA

Machine Learning Engineer jobs in San Mateo, California are concentrated in the Hillsdale, downtown, and Bay Meadows districts, driven by fintech, enterprise software, and healthcare technology employers. Companies actively hiring include Roblox, BigHat Biosciences, and Skydio. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles1,026+
Top employerRoblox
Work type78% Hybrid
Top credentialBachelor's degree
Companies hiring10

Showing 5 of 1,026+ Machine Learning Engineer jobs

Upstart
Director of Product, Machine Learning & Decisioning Platforms
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Upstart
Added 1d ago
Director of Product, Machine Learning & Decisioning Platforms
Upstart
San Mateo, California
Project & Program Management
Solutions Engineering & Architecture
Technical Program Management
$216k - $299k/yr
Remote (US)
Bachelor's degree
1,001-5,000

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Roblox
Senior/Principal Platform Engineer, ML Platform
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Roblox
Added 2d ago
Senior/Principal Platform Engineer, ML Platform
Roblox
San Mateo, California
Compliance & Risk
Health & Safety
Project Management
$260k - $345k/yr
Bachelor's degree
1,001-5,000

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Roblox
Principal Machine Learning Engineer, Alt Defense
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Roblox
Added 1w ago
Principal Machine Learning Engineer, Alt Defense
Roblox
San Mateo, California
AI (Artificial Intelligence)
Data Science
$329k - $399k/yr
Doctoral degree in Computer Science
1,001-5,000

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BigHat Biosciences
Machine Learning Engineer
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BigHat Biosciences
Added 2w ago
Machine Learning Engineer
BigHat Biosciences
San Mateo, California
AI (Artificial Intelligence)
Cloud Engineering
Solutions Engineering & Architecture
$150k - $200k/yr
Hybrid
Master's degree

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BigHat Biosciences
Machine Learning Scientist
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BigHat Biosciences
Added 2w ago
Machine Learning Scientist
BigHat Biosciences
San Mateo, California
AI (Artificial Intelligence)
Cloud Engineering
Solutions Engineering & Architecture
$150k - $200k/yr
Hybrid
Doctoral degree in Computer Science

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See All 1,026+ Machine Learning Engineer Jobs in San Mateo

Find roles in San Mateo that match your experience and apply in just a few clicks.

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Machine Learning Engineer Job Market in San Mateo

Who's Hiring

  • Roblox
    Roblox599
  • BigHat Biosciences
    BigHat Biosciences86
  • Skydio
    Skydio43
  • Upstart
    Upstart43
  • Skild AI
    Skild AI43

Top Industries Hiring

  • Technology & Software470
  • Gaming & Esports43
  • Aerospace & Defense43
  • Artificial Intelligence43

Machine Learning Engineer Jobs in San Mateo: Frequently Asked Questions

How do I get a machine learning engineer job in San Mateo?

Focus your search on San Mateo's fintech corridor, enterprise SaaS companies, and health tech firms clustered around the Caltrain corridor and Bay Meadows. Employers in these sectors prioritize hands-on experience with production ML systems, not just research. Candidates who can demonstrate deployment work, including model monitoring and data pipeline ownership, stand out in this market over candidates with purely academic backgrounds.

Which companies hire machine learning engineers in San Mateo?

Companies currently hiring machine learning engineers in San Mateo include Roblox, BigHat Biosciences, and Skydio, per current listings on Migrate Mate as of September 2026. San Mateo's employer mix leans toward mid-size fintech and enterprise software companies rather than large consumer tech, so many openings sit within product or data engineering teams rather than standalone AI research groups.

Are there remote machine learning engineer jobs in San Mateo?

Yes, though it varies: machine learning engineering skews more remote-compatible than hands-on engineering roles because much of the work involves code, data, and cloud infrastructure rather than physical hardware. About 86% of machine learning engineer openings tied to San Mateo are remote or hybrid as of September 2026, with fully remote roles most common in model development and experimentation work rather than on-site MLOps or data center-adjacent positions.

How can I get a machine learning engineer job in San Mateo with little or no experience?

The most realistic entry path in San Mateo is through data analyst or data engineer roles at local fintech and SaaS companies, then transitioning into ML work once you have internal credibility and production data experience. Entry-level ML roles at San Mateo employers often appear under titles like junior data scientist or ML engineer I. Building a portfolio of deployed models, even personal projects, is more persuasive locally than certifications alone.

Which industries hire the most machine learning engineers in San Mateo?

San Mateo machine learning engineer roles concentrate in Technology & Software, Gaming & Esports, and Aerospace & Defense, based on current listings on Migrate Mate as of September 2026. San Mateo's position between San Francisco and Silicon Valley has attracted a dense cluster of fintech and enterprise software companies that rely on ML for fraud detection, personalization, and workflow automation, making those sectors the primary drivers of local demand.

See All 1,026+ Machine Learning Engineer Jobs in San Mateo

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