OPT Bioinformatics Jobs
Bioinformatics roles sit at the intersection of biology, computer science, and data analysis, making them a strong fit for OPT work authorization. Most positions require a relevant degree in computational biology, bioinformatics, or a related STEM field, which also qualifies you for the 24-month STEM OPT extension.
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Get Access To All JobsReady to redefine what's possible in molecular diagnostics?
Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
We are looking for a Bioinformatics Intern, Prenatal to join and support our Bioinformatics team in developing bioinformatics pipelines and analyzing next-generation DNA sequencing data. This position will focus on an analysis and/or development project with guidance from Bioinformatics team members. BTO is a dynamic, start-up environment that requires adaptability and the ability to quickly learn and apply new concepts. This internship will provide valuable mentorship from BI Associates and BI Senior Scientists, hands-on experience, and professional development opportunities. The Bioinformatics Intern is a full-time onsite position in our Menlo Park office for 10 weeks.
Responsibilities:
- Conduct a research and/or development project centered on one of our prenatal assays
- Improve next-generation sequencing analysis pipelines under the guidance of Bioinformatics team members
- Communicate through presentations, written reports, and/or code review
- Collaborate with scientists and support new scientific insights
Requirements
- Currently enrolled in a Bachelor's or Master's program in Bioinformatics, Biology, Computational Biology, Computer Science, Bioengineering, Physics, or other related fields
- Strong programming skills in Python and R
- High mathematical and statistical aptitude
- Great attention to detail
- Curious about pursuing a career in Bioinformatics
Nice-To-Haves:
- Familiarity with MS Excel, bash, AWS, SQL, and git
- Research experience in bioinformatics, biology, or physical sciences
- Molecular biology (DNA purification, PCR, electrophoresis) or next-generation DNA sequencing laboratory experience
Benefits And Perks:
- Working with a team of 'rockstars' who bring out the best in everyone
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousand patients
- Free daily on-site lunches provided from top eateries
- Latest and greatest hardware (laptop, lab equipment, facilities)
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of (1) competitive base pay, and (2) the opportunity for professional growth.
For this position, the base pay rate is $25 per hour.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
For more information about how we protect your information, we encourage you to review our Privacy Policy.
BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA, a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact
Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth
From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding, including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition
Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future
Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.
Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com
Ready to redefine what's possible in molecular diagnostics?
Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
We are looking for a Bioinformatics Intern, Prenatal to join and support our Bioinformatics team in developing bioinformatics pipelines and analyzing next-generation DNA sequencing data. This position will focus on an analysis and/or development project with guidance from Bioinformatics team members. BTO is a dynamic, start-up environment that requires adaptability and the ability to quickly learn and apply new concepts. This internship will provide valuable mentorship from BI Associates and BI Senior Scientists, hands-on experience, and professional development opportunities. The Bioinformatics Intern is a full-time onsite position in our Menlo Park office for 10 weeks.
Responsibilities:
- Conduct a research and/or development project centered on one of our prenatal assays
- Improve next-generation sequencing analysis pipelines under the guidance of Bioinformatics team members
- Communicate through presentations, written reports, and/or code review
- Collaborate with scientists and support new scientific insights
Requirements
- Currently enrolled in a Bachelor's or Master's program in Bioinformatics, Biology, Computational Biology, Computer Science, Bioengineering, Physics, or other related fields
- Strong programming skills in Python and R
- High mathematical and statistical aptitude
- Great attention to detail
- Curious about pursuing a career in Bioinformatics
Nice-To-Haves:
- Familiarity with MS Excel, bash, AWS, SQL, and git
- Research experience in bioinformatics, biology, or physical sciences
- Molecular biology (DNA purification, PCR, electrophoresis) or next-generation DNA sequencing laboratory experience
Benefits And Perks:
- Working with a team of 'rockstars' who bring out the best in everyone
- Open, transparent culture that includes weekly Town Hall meetings
- The ability to indirectly or directly change the lives of hundreds of thousand patients
- Free daily on-site lunches provided from top eateries
- Latest and greatest hardware (laptop, lab equipment, facilities)
- A variety of perks on campus (state of the art gym, restaurant)
- Free on-site EV charging (compatible with all EVs, including Tesla)
At BillionToOne, we are proud to offer a combination of (1) competitive base pay, and (2) the opportunity for professional growth.
For this position, the base pay rate is $25 per hour.
BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
For more information about how we protect your information, we encourage you to review our Privacy Policy.
BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA, a breakthrough that has already transformed the lives of over half a million patients worldwide.
Our Impact
Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
Our Growth
From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding, including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Our Recognition
Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Our Future
Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.
Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com
See all 44+ OPT Bioinformatics Jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new OPT Bioinformatics Jobs.
Get Access To All JobsTips for Finding OPT Sponsorship in Bioinformatics
Target STEM-designated programs
Your bioinformatics degree likely qualifies for the 24-month STEM OPT extension. Confirm your program's CIP code with your DSO before job searching, so you can accurately communicate your full authorization window to employers.
Lead with your technical stack
Hiring managers in bioinformatics screen for tools like Python, R, Nextflow, and cloud platforms. Listing these prominently on your resume signals immediate productivity and reduces hesitation around OPT authorization timelines.
Focus on research-driven employers
Pharmaceutical companies, genomics firms, and academic medical centers file OPT and H-1B visa paperwork regularly. These organizations have established immigration processes, making them far more receptive to candidates on work authorization.
Quantify your research contributions
Employers respond to measurable impact. Frame your work around datasets processed, pipeline runtime improvements, or publications contributed to. Concrete outcomes shift the conversation away from visa status toward your value.
Apply before your OPT start date
Bioinformatics hiring processes at research institutions can run eight to twelve weeks. Starting your search three to four months before graduation gives you enough runway to have an offer in hand before OPT begins.
Clarify E-Verify requirements early
STEM OPT extension employers must be enrolled in E-Verify. Before investing time in an application, confirm the company meets this requirement, especially at smaller biotech startups where compliance processes are less established.
Bioinformatics OPT: Frequently Asked Questions
Do bioinformatics jobs qualify for the STEM OPT extension?
Most do. Bioinformatics, computational biology, and biostatistics degrees are commonly classified under STEM CIP codes that qualify for the 24-month STEM OPT extension. Your specific eligibility depends on your program's CIP code, not just the degree title, so verify with your DSO before assuming you qualify.
How do I find bioinformatics employers willing to sponsor OPT students?
Migrate Mate filters job listings specifically for employers open to OPT and visa sponsorship, which saves time compared to applying broadly and discovering authorization issues late in the process. Pharmaceutical companies, genomics research labs, and large hospital systems are the most consistent sources of OPT-friendly bioinformatics roles.
Can I work as a bioinformatics contractor or freelancer on OPT?
Self-employment is technically permitted on OPT if you own at least 50 percent of the business and the work is directly related to your degree. However, contract work for a single client without that structure may not qualify. STEM OPT extension specifically prohibits self-employment, so consult your DSO before pursuing contract arrangements.
What happens to my OPT if my bioinformatics job is remote for an employer based outside the U.S.?
OPT requires that the job be with a US-based employer. Working remotely for a company incorporated and operating outside the United States does not satisfy OPT employment requirements, even if you are physically located in the U.S.. The employer must have a legitimate U.S. presence and the work must be in your field of study.
Does part-time bioinformatics work count toward OPT employment requirements?
Yes, but with conditions. During pre-completion OPT you are limited to 20 hours per week while school is in session. During post-completion OPT you must work at least 20 hours per week to remain in valid status. Part-time bioinformatics roles at research institutions or biotech companies can satisfy this threshold.