Senior Level Principal Chemist Jobs
Senior level principal chemist jobs place experienced scientists in charge of research direction, methodology ownership, and the cross-functional teams or programs that deliver results. Roles are concentrated across Electronics & Hardware, Biotechnology & Pharmaceuticals, and Consulting & Professional Services, with a mix of on-site, hybrid, and remote positions available, and employers like Eisai, Alsym Energy, and Solstice Advanced Materials hiring at this level now.
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See related jobsAs a Chemist I at Solstice, you will employ critical thinking and use your knowledge of chemistry fundamentals to help Solstice deliver innovative solutions that meet the evolving needs of our customers.
You will work under direct and/or indirect supervision and alongside talented chemists to develop and optimize analytical test methods, conduct experiments, and collaborate with cross-functional teams to ensure successful product development of Solstice's next generation of products.
You will be a part of a group of highly committed professionals who provide expertise and ensure the success of our methods and programs. You will report directly to our Chemist Supervisor and work out of our Spokane, WA location (please note this is not a remote or hybrid role). In this role, you will impact on the development of innovative solutions and contribute to the success of our projects and programs.
******** This position requires availability to work a non-traditional schedule, including evening and overnight shifts, weekends, and potentially weekend overnight shifts. Candidates must be willing and able to work outside of standard Monday–Friday business hours, as operational needs require. ************
KEY RESPONSIBILITIES
- Run chemical experiments
- Perform analytical tests
- Develop and validate quality control test methodologies
- Provide technical expertise in analytical chemistry and instrument operation and maintenance
- Provide high-quality and timely analysis
- Generate continuous improvement ideas
- Ensure compliance with the Solstice Spokane Quality Management System
About Solstice Advanced Materials
Solstice Advanced Materials is a leading global specialty materials company that advances science for smarter outcomes. Solstice offers high-performance solutions that enable critical industries and applications, including refrigerants, semiconductor manufacturing, data center cooling, nuclear power, protective fibers, healthcare packaging and more. Solstice is recognized for developing next-generation materials through some of the industry's most renowned brands such as Solstice®, Genetron®, Aclar®, Spectra®, Fluka™, and Hydranal™. Partnering with over 3,000 customers across more than 120 countries and territories and supported by a robust portfolio of over 5,700 patents, Solstice’s approximately 4,000 employees worldwide drive innovation in materials science. For more information, visit Advanced Materials .
- Design chemical processes
- Run chemical experiments
- Perform chemistry tests
- Aid in the development of manufacturing procedures
- Develop and validate quality control test methodologies
- Provide technical expertise in analytical chemistry and instrument operation and maintenance
- Provide highquality and timely analysis
- Generate continuous improvement ideas
YOU MUST HAVE
- Bachelor’s degree in chemistry or related science. 6+ years of experience working in a laboratory environment, which may combine educational experience plus working experience.
WE VALUE
- Experience with analytical instrumentation
- High attention to detail Ability to work under minimal supervision
COMPENSATION
The annual base salary range for this position is $70,548K - $88,236K. Please note that this salary information serves as a general guideline. Solstice Advanced Materials considers various factors when extending an offer, including but not limited to the scope and responsibilities or the position, the candidate's work experience, education and training, key skills, as well as market and business considerations.
BENEFITS OF WORKING FOR SOLSTICE ADVANCED MATERIAL
In addition to a competitive salary, leading-edge work, and developing solutions side-by-side with dedicated experts in their fields, Solstice Advanced Materials employees are eligible for a comprehensive benefits package. This package includes employer-subsidized Medical, Dental, Vision, and Life Insurance; Short-Term and Long-Term Disability; 401(k) match, Flexible Spending Accounts, Health Savings Accounts
Solstice is an equal opportunity employer. Qualified applicants will be considered without regard to age, race, creed, color, national origin, ancestry, marital status, affectional or sexual orientation, gender identity or expression, disability, nationality, sex, religion, or veteran status.
As a Chemist I at Solstice, you will employ critical thinking and use your knowledge of chemistry fundamentals to help Solstice deliver innovative solutions that meet the evolving needs of our customers.
You will work under direct and/or indirect supervision and alongside talented chemists to develop and optimize analytical test methods, conduct experiments, and collaborate with cross-functional teams to ensure successful product development of Solstice's next generation of products.
You will be a part of a group of highly committed professionals who provide expertise and ensure the success of our methods and programs. You will report directly to our Chemist Supervisor and work out of our Spokane, WA location (please note this is not a remote or hybrid role). In this role, you will impact on the development of innovative solutions and contribute to the success of our projects and programs.
******** This position requires availability to work a non-traditional schedule, including evening and overnight shifts, weekends, and potentially weekend overnight shifts. Candidates must be willing and able to work outside of standard Monday–Friday business hours, as operational needs require. ************
KEY RESPONSIBILITIES
- Run chemical experiments
- Perform analytical tests
- Develop and validate quality control test methodologies
- Provide technical expertise in analytical chemistry and instrument operation and maintenance
- Provide high-quality and timely analysis
- Generate continuous improvement ideas
- Ensure compliance with the Solstice Spokane Quality Management System
About Solstice Advanced Materials
Solstice Advanced Materials is a leading global specialty materials company that advances science for smarter outcomes. Solstice offers high-performance solutions that enable critical industries and applications, including refrigerants, semiconductor manufacturing, data center cooling, nuclear power, protective fibers, healthcare packaging and more. Solstice is recognized for developing next-generation materials through some of the industry's most renowned brands such as Solstice®, Genetron®, Aclar®, Spectra®, Fluka™, and Hydranal™. Partnering with over 3,000 customers across more than 120 countries and territories and supported by a robust portfolio of over 5,700 patents, Solstice’s approximately 4,000 employees worldwide drive innovation in materials science. For more information, visit Advanced Materials .
- Design chemical processes
- Run chemical experiments
- Perform chemistry tests
- Aid in the development of manufacturing procedures
- Develop and validate quality control test methodologies
- Provide technical expertise in analytical chemistry and instrument operation and maintenance
- Provide highquality and timely analysis
- Generate continuous improvement ideas
YOU MUST HAVE
- Bachelor’s degree in chemistry or related science. 6+ years of experience working in a laboratory environment, which may combine educational experience plus working experience.
WE VALUE
- Experience with analytical instrumentation
- High attention to detail Ability to work under minimal supervision
COMPENSATION
The annual base salary range for this position is $70,548K - $88,236K. Please note that this salary information serves as a general guideline. Solstice Advanced Materials considers various factors when extending an offer, including but not limited to the scope and responsibilities or the position, the candidate's work experience, education and training, key skills, as well as market and business considerations.
BENEFITS OF WORKING FOR SOLSTICE ADVANCED MATERIAL
In addition to a competitive salary, leading-edge work, and developing solutions side-by-side with dedicated experts in their fields, Solstice Advanced Materials employees are eligible for a comprehensive benefits package. This package includes employer-subsidized Medical, Dental, Vision, and Life Insurance; Short-Term and Long-Term Disability; 401(k) match, Flexible Spending Accounts, Health Savings Accounts
Solstice is an equal opportunity employer. Qualified applicants will be considered without regard to age, race, creed, color, national origin, ancestry, marital status, affectional or sexual orientation, gender identity or expression, disability, nationality, sex, religion, or veteran status.
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Senior Level Principal Chemist Jobs: Frequently Asked Questions
How do I get a senior level principal chemist job?
Employers at this level look for candidates who have led complex research programs from conception through delivery, not just contributed to them. Demonstrating technical depth in a specialized chemistry discipline, a record of independent problem-solving, and experience mentoring junior scientists or guiding cross-functional teams gives candidates the clearest edge. Publications, patents, or documented process improvements strengthen a senior-level application considerably.
Which companies hire senior level principal chemists?
Companies hiring senior level principal chemists right now include Eisai, Alsym Energy, and Solstice Advanced Materials, based on current listings on Migrate Mate as of November 2026. Hiring at this level tends to concentrate in large pharmaceutical, specialty chemical, materials science, and consumer products organizations that maintain dedicated R&D or formulation functions.
Are there remote senior level principal chemist jobs?
Yes, though laboratory-dependent roles remain largely on-site. About 25% of senior level principal chemist openings are remote or hybrid as of November 2026, with remote availability more common in regulatory, computational, or technical strategy roles where bench work is not required day-to-day.
What makes a principal chemist role senior level?
Senior level principal chemist roles are defined by scope and ownership. Rather than executing assigned work, senior professionals set research priorities, own project outcomes end-to-end, and are accountable for technical decisions that affect product development or manufacturing. Mentoring chemists at earlier career stages and representing the chemistry function in cross-disciplinary or leadership discussions are standard expectations at this level.
Which industries hire the most senior level principal chemists?
Senior Level principal chemist roles concentrate in Electronics & Hardware, Biotechnology & Pharmaceuticals, and Consulting & Professional Services, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because they require deep subject-matter expertise to advance complex formulations, regulatory submissions, or materials innovation programs that cannot be managed by generalist scientists.