Senior Level Principal Product Development Engineer Jobs

Senior level principal product development engineer jobs place experienced engineers in charge of product architecture decisions, cross-functional technical direction, and the execution of complex development programs from concept through launch. Openings concentrate in Medical Devices, Distribution & Wholesale, and Biotechnology & Pharmaceuticals, with a mix of on-site, remote, and hybrid settings, and employers like AbbVie, Comcast, and Immunome hiring at this level now.

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Overview

Open roles6
Top stateKansas
Top employerAbbVie
Top cityTopeka, KS
Work type67% On-site
Top industryMedical Devices

Showing 5 of 6+ Senior Level Principal Product Development Engineer jobs

Principal Product Development Engineer
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Principal Product Development Engineer
Comcast
Philadelphia, Pennsylvania
Product Management
Project & Program Management
Technical Product & Program Management
Project Management
Technical Program Management
$143k - $211k/yr
On-Site
Bachelor's
10,000+

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Principal Scientist I, Biologics Drug Product Development
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Added 1w ago
Principal Scientist I, Biologics Drug Product Development
AbbVie
North Chicago, Illinois
Laboratory Research
Biotech & Life Sciences
Clinical Trials & Medical Research
$125k - $237k/yr
On-Site
Doctorate
10,000+

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Principal Scientist - Fresh Food Product Development
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Added 1mo ago
Principal Scientist - Fresh Food Product Development
Hill's Pet Nutrition
Topeka, Kansas
Biotech & Life Sciences
Environmental & Physical Sciences
Laboratory Research
Research & Academia
$138k - $184k/yr
Hybrid
Master of Science
1,001-5,000

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Senior / Principal Scientist, Formulation and Drug Product Development
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Added 2mo ago
Senior / Principal Scientist, Formulation and Drug Product Development
Immunome, Inc.
Bothell, Washington
Laboratory Research
Biotech & Life Sciences
Clinical Trials & Medical Research
Allied Health
Clinical Trials
Pharmacy
$156k - $190k/yr
On-Site
Doctorate

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Sr Principal Engineer, Product Development
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Added 2mo ago
Sr Principal Engineer, Product Development
Integra LifeSciences
Mansfield, Massachusetts
Academic & Educational Administration
Corporate Training & Learning Development
Executive Leadership & C-Suite
Human Resources
$167k - $229k/yr
Hybrid
Bachelor's degree in mechanical engineering
1,001-5,000

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Senior Level Principal Product Development Engineer Job Market

Who's Hiring

AbbVie1 open role
Comcast1 open role
Immunome1 open role

Top Industries Hiring

  • Medical Devices
  • Distribution & Wholesale
  • Biotechnology & Pharmaceuticals

Senior Level Principal Product Development Engineer Jobs: Frequently Asked Questions

How do I get a senior level principal product development engineer job?

Employers at this level want candidates who have owned product development programs end to end, not just contributed to them. Demonstrating that you have set technical direction, resolved cross-functional conflicts, and shipped products that met both performance and business targets gives you the clearest edge. A portfolio of outcomes, not just responsibilities, is what separates strong applicants from the rest.

Which companies hire senior level principal product development engineers?

Companies hiring senior level principal product development engineers right now include AbbVie, Comcast, and Immunome, based on current listings on Migrate Mate as of November 2026. Hiring at this level tends to concentrate in organizations running complex product lines where deep technical ownership and cross-team leadership are built into the role from day one.

Are there remote senior level principal product development engineer jobs?

Yes, though on-site and hybrid arrangements are common given the hands-on collaboration these roles often require. About 33% of senior level principal product development engineer openings are remote or hybrid as of November 2026, so the options exist and are worth filtering for when you search current listings.

What makes a principal product development engineer role senior level?

Senior level principal product development engineer roles are defined by the scope of technical authority and the expectation of independent judgment. Engineers at this stage own product development strategy for entire systems or programs, mentor junior and mid-level engineers, and are accountable for outcomes rather than tasks. The role bridges deep individual technical contribution with organizational influence.

Which industries hire the most senior level principal product development engineers?

Senior Level principal product development engineer roles concentrate in Medical Devices, Distribution & Wholesale, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of November 2026. These sectors drive hiring at this level because they run product lines with high technical complexity, long development cycles, and a consistent need for engineers who can lead programs without close supervision.