Senior Level Principal R&D Engineer Jobs

Senior level principal r&d engineer jobs place experienced engineers at the center of product innovation, where they own technical direction, drive cross-functional research programs, and mentor the teams building next-generation solutions. Openings are spread across on-site, hybrid, and remote settings in Technology & Software, Biotechnology & Pharmaceuticals, and Education, with Riot Games, AbbVie, and BD hiring at this level now.

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Overview

Open roles12
Top stateCalifornia
Top employerRiot Games
Top cityLos Angeles, CA
Work type75% On-site
Top industryTechnology

Showing 5 of 12+ Senior Level Principal R&D Engineer jobs

Principal R&D Scientist
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Added 3d ago
Principal R&D Scientist
Dimer Instruments
Santa Barbara County, California
Laboratory Research
Biotech & Life Sciences
Specialized Engineering
Mechanical Engineering
Electrical Engineering
Engineering (Non-Software)
On-Site
Doctorate

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Principal R&D Engineer
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Added 2w ago
Principal R&D Engineer
Skyworks Solutions
Richardson, Texas
Academic & Educational Administration
Corporate Training & Learning Development
Executive Leadership & C-Suite
Human Resources
$123k - $255k/yr
Doctorate in mechanical engineering
5,001-10,000

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Principal Engineer - Cybersecurity R&D
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Added 1mo ago
Principal Engineer - Cybersecurity R&D
Hewlett Packard Enterprise | HPE
San Juan, PR
Cybersecurity
Technical Product & Program Management
Security Engineering
Technical Program Management
Hybrid
Bachelor's
10,000+

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Principal Research Scientist I - Analytical R&D
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Added 2mo ago
Principal Research Scientist I - Analytical R&D
AbbVie
North Chicago, Illinois
Clinical Trials
Laboratory Research
Research & Academia
$125k - $237k/yr
Bachelor of Science
10,000+

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Principal Engineer – Applied ML/AI Algorithms R&D for Advanced Patient Monitoring
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Added 3mo ago
Principal Engineer – Applied ML/AI Algorithms R&D for Advanced Patient Monitoring
BD
Laguna Canyon, California
Automation QA
Electrical Engineering
Engineering (Non-Software)
Specialized Engineering
$130k - $207k/yr
Bachelor of Science
10,000+

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Senior Level Principal R&D Engineer Job Market

Who's Hiring

Riot Games3 open roles
AbbVie2 open roles
BD1 open role

Top Industries Hiring

  • Technology & Software
  • Biotechnology & Pharmaceuticals
  • Education
  • Medical Devices
  • Chemicals & Materials

Senior Level Principal R&D Engineer Jobs: Frequently Asked Questions

How do I get a senior level principal r&d engineer job?

Employers at this level look for candidates who have led end-to-end research and development programs, not just contributed to them. Demonstrating a portfolio of patented innovations, published work, or products shipped at scale strengthens your candidacy significantly. Showing that you have mentored junior engineers and influenced roadmap decisions signals the ownership mindset these roles require.

Which companies hire senior level principal r&d engineers?

Companies hiring senior level principal r&d engineers right now include Riot Games, AbbVie, and BD, based on current listings on Migrate Mate as of November 2026. Hiring at this level tends to concentrate in large technology, defense, medical device, and industrial manufacturers with dedicated R&D functions and long-horizon product cycles.

Are there remote senior level principal r&d engineer jobs?

Yes, though availability varies by industry and discipline. About 25% of senior level principal r&d engineer openings are remote or hybrid as of November 2026, with hybrid arrangements more common in roles tied to lab work, hardware development, or regulated manufacturing environments where on-site presence is periodically required.

What makes a principal r&d engineer role senior level?

A senior level principal r&d engineer owns the technical strategy for a research domain, not just individual deliverables. The role carries accountability for program outcomes, requires guiding and evaluating the work of other engineers, and demands deep enough expertise to resolve ambiguous problems without escalation. Scope, autonomy, and cross-functional influence are what separate it from mid-level positions.

Which industries hire the most senior level principal r&d engineers?

Senior Level principal r&d engineer roles concentrate in Technology & Software, Biotechnology & Pharmaceuticals, and Education, based on current listings on Migrate Mate as of November 2026. These sectors invest heavily in sustained innovation pipelines, which drives consistent demand for senior-level engineers who can lead research functions and translate technical findings into commercial outcomes.