Registered Nurse Jobs in Wilmington, DE

Registered Nurse jobs in Wilmington, Delaware are concentrated in the Riverfront medical corridor, the Brandywine area, and Trolley Square, across hospital systems, long-term care, and outpatient specialty clinics. Employers hiring right now include Trinity Health, ChristianaCare, and Nemours Children's Health. See the openings below and apply to the ones that match your experience.

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Overview

Open roles112+
Top employerTrinity Health
Work type95% On-site
Top credentialBLS Certification
Companies hiring31

Showing 5 of 112+ Registered Nurse jobs

ChristianaCare
Registered Nurse (RN)
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ChristianaCare
New 7h ago
Registered Nurse (RN)
ChristianaCare
Wilmington, Delaware
Nursing
Healthcare Administration
Patient Services & Wellbeing
$41 - $66/hr
On-Site
None
10,000+

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AccentCare
Registered Nurse, Hospice IPC
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AccentCare
New 12h ago
Registered Nurse, Hospice IPC
AccentCare
Wilmington, Delaware
Nursing
Healthcare Administration
Patient Services & Wellbeing
Caregiving & Elderly Support
$43.00 - $46.00/hr
On-Site
Associate's
10,000+

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IVX Health
Infusion Registered Nurse (RN)
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IVX Health
New 23h ago
Infusion Registered Nurse (RN)
IVX Health
Wilmington, Delaware
Healthcare Administration
Nursing
Patient Services & Wellbeing
PALS Certification
501-1,000

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BAYADA Home Health Care
Registered Nurse - One on One Adult Home Care
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BAYADA Home Health Care
Added 1d ago
Registered Nurse - One on One Adult Home Care
BAYADA Home Health Care
Wilmington, Delaware
Healthcare Administration
Nursing
Patient Services & Wellbeing
Nursing Diploma
10,000+

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Complete Care at Hillside
RN Nurse Practice Educator Infection Preventionist
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Complete Care at Hillside
Added 1d ago
RN Nurse Practice Educator Infection Preventionist
Complete Care at Hillside
Wilmington, Delaware
Healthcare Administration
Nursing
Patient Services & Wellbeing

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See All 112+ Registered Nurse Jobs in Wilmington

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Registered Nurse Job Market in Wilmington

Who's Hiring

  • Trinity Health
    Trinity Health26
  • ChristianaCare
    ChristianaCare20
  • Nemours Children's Health
    Nemours Children's Health9
  • Coral Springs Rehabilitation and Healthcare Center
    Coral Springs Rehabilitation and Healthcare Center7
  • Fresenius Medical Care
    Fresenius Medical Care5

Top Industries Hiring

  • Healthcare & Medical Services56
  • Insurance6
  • Non-Profit & Social Services4
  • Education1
  • Technology & Software1

Registered Nurse Jobs in Wilmington: Frequently Asked Questions

How do I get a registered nurse job in Wilmington?

Focus on Wilmington's hospital systems, rehabilitative care facilities, and the growing outpatient and specialty clinic network near the Riverfront and Brandywine neighborhoods. Candidates with acute care or med-surg experience move quickest in this market. Certifications in critical care, oncology, or pediatrics give a real edge with the larger health systems downtown, and bilingual nurses find added demand in community health settings serving Wilmington's diverse west-side neighborhoods.

Which companies hire registered nurses in Wilmington?

Employers hiring registered nurses in Wilmington right now include Trinity Health, ChristianaCare, and Nemours Children's Health, based on current listings on Migrate Mate as of July 2026. Wilmington's hiring mix includes large regional health systems, specialty surgical centers, and long-term care and rehabilitation facilities concentrated in and around the downtown and Brandywine medical corridors.

Are there remote registered nurse jobs in Wilmington?

Yes, though remote opportunities are limited for registered nurses given the hands-on nature of most clinical roles. About 5% of registered nurse openings tied to Wilmington are remote or hybrid as of July 2026, skewing toward telehealth triage, utilization review, and case management positions rather than bedside or procedural roles.

How can I get a registered nurse job in Wilmington with little or no experience?

The most realistic entry path in Wilmington is a new-graduate residency program at one of the city's larger hospital systems, which provide structured clinical mentorship before moving into independent patient assignments. Long-term care facilities and rehabilitation centers along the Riverfront corridor regularly hire new graduates for med-surg and general floor roles. Completing clinical rotations at a Wilmington facility and expressing interest in a full-time position before graduation is the most direct route to an offer.

Which industries hire the most registered nurses in Wilmington?

Wilmington registered nurse roles concentrate in Healthcare & Medical Services, Insurance, and Non-Profit & Social Services, based on current listings on Migrate Mate as of July 2026. Wilmington's position as northern Delaware's primary healthcare hub, combined with its growing outpatient and specialty care infrastructure, drives consistent demand across these sectors throughout the year.

See All 112+ Registered Nurse Jobs in Wilmington

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