Registered Nurse Operating Room Jobs in St. Louis, MO
Registered Nurse Operating Room jobs in St. Louis are concentrated around the Central West End medical corridor, Barnes-Jewish and Cortex districts, and the South City hospital campuses, with demand running strong across academic medical centers, health systems, and surgical specialty centers. Employers hiring right now include LiveWell Homecare Agency, BJC HealthCare, and Mercy. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 93+ Registered Nurse Operating Room jobs



- Saint Louis, Missouri
- Nursing Services
- Days
- Full-Time
- 108901
- $32.00 – $48.28 / hour (Salary or hourly rate is based on job qualifications and relevant work experience)
Job Description
- OR experience preferred
- 4/10 hour shifts (615A start time)
- Cardiothoracic position
- Weekday/weekend and holiday call requirement
- 24/7 cardiac services include minimally invasive, heart failure, and heart transplants, thoracic, robotic and lung transplants plus vascular and endovascular surgery
- Bonus eligible
- Comprehensive benefit
Overview
Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in Missouri and is ranked as one of the nation's top hospitals by U.S. News & World Report. Barnes-Jewish Hospital's staff is composed of full-time academic faculty and community physicians of Washington University School of Medicine, supported by a house staff of residents, interns, fellows and other medical professionals. Recognizing its excellence in nursing care, Barnes-Jewish Hospital was the first adult hospital in Missouri to be certified as a Magnet Hospital by the American Nurses Credentialing Center.
At Barnes-Jewish Hospital, Perioperative Services team members (RN, RNFA, ST) find the kind of fast-paced environment that will test their professional judgment and critical thinking skills, and encourage tremendous growth. It's an exhilarating place to build a nursing career. Here, you'll work with world-renowned surgeons and anesthesiologists, assist on unique and complex procedures, work with the latest technologies and treatments and play a vital role in developing new procedures and treatment protocols. In fact, people from all over the nation and the world come to Barnes-Jewish for our surgical specialties.
Preferred Qualifications
Role Purpose
Provides direct patient care activities including assessment, diagnosis, planning implementation, and evaluation within the guidelines of the standards of nursing care.
Responsibilities
- Promotes patient and family centered care in a healing environment. Educates patients and their families on how to manage their illness or injury, including post treatment home care needs and medication administration.
- Participates in activities that promote patient safety, quality and regulatory compliance. Participates in professional development.
- Develops, implements, and documents individual plans of care with defined goals in collaboration with other members of the interprofessional team and patient, family or caregiver in accordance with the established guidelines and standards of nursing care. Proactively plans and ensures communication of the plan of care across the continuum of care.
- Uses critical nursing skills to assess and evaluate physical, psychosocial, and emotional needs according to standards of care. Assess patient preferences and barriers to involvement in care, including their values, emotional, spiritual, cultural, and population-specific needs.
- BJC has determined this is a safety-sensitive position. The ability to work in a constant state of alertness and in a safe manner is an essential function of this job.
Minimum Requirements
Education
- Nursing Diploma/Associate's
- Nursing
Experience
- No Experience
Supervisor Experience
- No Experience
Licenses & Certifications
- RN
Preferred Requirements
Education
- Bachelor's Degree
- Nursing
Experience
- <2 years
Benefits and Legal Statement
BJC Total Rewards
At BJC we’re committed to providing you and your family with benefits and resources to help you manage your physical, emotional, social and financial well-being.
- Comprehensive medical, dental, vison, life insurance, and legal services available first day of the month after hire date
- Disability insurance* paid for by BJC
- Annual 4% BJC Automatic Retirement Contribution
- 401(k) plan with BJC match
- Tuition Assistance available on first day
- BJC Institute for Learning and Development
- Health Care and Dependent Care Flexible Spending Accounts
- Paid Time Off benefit combines vacation, sick days, holidays and personal time
- Adoption assistance
To learn more, go to our Benefits Summary.
- Not all benefits apply to all jobs
The above information on this description has been designed to indicate the general nature and level of work performed by employees in this position. It is not designed to contain or be interpreted as an exhaustive list of all responsibilities, duties and qualifications required of employees assigned to this job. Equal Opportunity Employer
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Find JobsRegistered Nurse Operating Room Job Market in St. Louis
Who's Hiring
- LiveWell Homecare Agency34L
- BJC HealthCare26

- Mercy14

- American Traveler8

- SSM Health4

Registered Nurse Operating Room Jobs in St. Louis: Frequently Asked Questions
How do I get a registered nurse operating room job in St. Louis?
St. Louis hiring concentrates in its academic medical systems and large health network affiliates, particularly around the Central West End and midtown hospital campuses. Candidates with scrub and circulating experience across general, cardiac, or orthopedic surgery move fastest here. Perioperative certifications like CNOR sharpen your competitiveness with the larger systems. Reaching out to surgical staffing coordinators directly at St. Louis health networks often surfaces openings before they appear publicly.
Which companies hire registered nurse operating rooms in St. Louis?
St. Louis registered nurse operating room roles are posted by LiveWell Homecare Agency, BJC HealthCare, and Mercy and others right now, based on current listings on Migrate Mate as of September 2026. The local market is anchored by large academic health systems, regional hospital networks, and ambulatory surgical centers spread throughout the city and its western suburbs.
How can I get a registered nurse operating room job in St. Louis with little or no experience?
The most realistic entry path in St. Louis is through a perioperative nurse residency or OR internship offered by the city's larger academic health systems, which are designed specifically for RNs without prior surgical experience. Starting in a medical-surgical unit at a St. Louis community hospital and requesting elective procedure exposure builds the clinical foundation employers look for. Volunteering for weekend on-call coverage during training also demonstrates commitment that local hiring managers notice.
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