Registered Nurse Operating Room Jobs in St. Louis, MO

Registered Nurse Operating Room jobs in St. Louis are concentrated around the Central West End medical corridor, Barnes-Jewish and Cortex districts, and the South City hospital campuses, with demand running strong across academic medical centers, health systems, and surgical specialty centers. Employers hiring right now include LiveWell Homecare Agency, BJC HealthCare, and Mercy. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles93
Top employerLiveWell Homecare Agency
Top credentialNursing Diploma
Companies hiring7

Showing 5 of 93+ Registered Nurse Operating Room jobs

BJC HealthCare
Clinical Nurse Operating Room
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BJC HealthCare
Added 1d ago
Clinical Nurse Operating Room
BJC HealthCare
St. Louis, Missouri
Caregiving & Elderly Support
Healthcare Administration
Nursing
Patient Services & Wellbeing
$32 - $48.28/hr
Nursing Diploma
10,000+

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L
Assistant Nurse Manager – Operating Room
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L
Added 4d ago
Assistant Nurse Manager – Operating Room
LiveWell Homecare Agency
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Managed Registered Nurses (RNs)

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L
MRI Technologist – Operating Room (OR) – Days (3 x 12’s)
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L
Added 5d ago
MRI Technologist – Operating Room (OR) – Days (3 x 12’s)
LiveWell Homecare Agency
St. Louis, Missouri
Clinical Support
Healthcare Administration
Medical Specialists
CPR Certification

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L
Clinical Nurse – Operating Room
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L
Added 6d ago
Clinical Nurse – Operating Room
LiveWell Homecare Agency
St. Louis, Missouri
Caregiving & Elderly Support
Healthcare Administration
Nursing
Patient Services & Wellbeing

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L
Clinical Nurse – Pediatric Operating Room
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L
Added 6d ago
Clinical Nurse – Pediatric Operating Room
LiveWell Homecare Agency
St. Louis, Missouri
Healthcare Administration
Nursing
Patient Services & Wellbeing
Nursing Diploma

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See All 93 Registered Nurse Operating Room Jobs in St. Louis

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Registered Nurse Operating Room Job Market in St. Louis

Who's Hiring

  • L
    LiveWell Homecare Agency34
  • BJC HealthCare
    BJC HealthCare26
  • Mercy
    Mercy14
  • American Traveler
    American Traveler8
  • SSM Health
    SSM Health4

Registered Nurse Operating Room Jobs in St. Louis: Frequently Asked Questions

How do I get a registered nurse operating room job in St. Louis?

St. Louis hiring concentrates in its academic medical systems and large health network affiliates, particularly around the Central West End and midtown hospital campuses. Candidates with scrub and circulating experience across general, cardiac, or orthopedic surgery move fastest here. Perioperative certifications like CNOR sharpen your competitiveness with the larger systems. Reaching out to surgical staffing coordinators directly at St. Louis health networks often surfaces openings before they appear publicly.

Which companies hire registered nurse operating rooms in St. Louis?

St. Louis registered nurse operating room roles are posted by LiveWell Homecare Agency, BJC HealthCare, and Mercy and others right now, based on current listings on Migrate Mate as of September 2026. The local market is anchored by large academic health systems, regional hospital networks, and ambulatory surgical centers spread throughout the city and its western suburbs.

How can I get a registered nurse operating room job in St. Louis with little or no experience?

The most realistic entry path in St. Louis is through a perioperative nurse residency or OR internship offered by the city's larger academic health systems, which are designed specifically for RNs without prior surgical experience. Starting in a medical-surgical unit at a St. Louis community hospital and requesting elective procedure exposure builds the clinical foundation employers look for. Volunteering for weekend on-call coverage during training also demonstrates commitment that local hiring managers notice.

See All 93 Registered Nurse Operating Room Jobs in St. Louis

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