Remote Senior AI Software Engineer Jobs

Remote Senior AI Software Engineer jobs are in active demand across the U.S., with remote-first firms and distributed engineering teams hiring senior ai software engineers to lead model development, deployment pipelines, and applied research from anywhere. Companies currently posting include CVS Health, Advanced Monitored Caregiving, and Serko. See the openings below and apply to the ones that match your experience.

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Overview

Open roles207+
Top employerCVS Health
Top industryHealthcare
Top credentialHigh school diploma or GED
Companies hiring100+

Showing 4 of 207+ Remote Senior AI Software Engineer jobs

BV Teck
Artificial Intelligence Security Engineer
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BV Teck
Added 1d ago
Artificial Intelligence Security Engineer
BV Teck
Remote
Cloud Engineering
Data Engineering
Data Science
$80k - $105k/yr
Remote (US)
Master's degree in cybersecurity
51-200

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Cyber Security Innovations
AI Developer/Engineer – Senior Software Developer, Application
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Cyber Security Innovations
Added 1d ago
AI Developer/Engineer – Senior Software Developer, Application
Cyber Security Innovations
Hyattsville, Maryland
Cloud & DevOps
Cloud Engineering
DevOps
Solutions Engineering & Architecture
Remote (US)
Master's degree

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General Dynamics Mission Systems
Senior Software Engineer, AI Platform / Semantic Layer
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General Dynamics Mission Systems
Added 1d ago
Senior Software Engineer, AI Platform / Semantic Layer
General Dynamics Mission Systems
Remote
Customer Support
Solutions Engineering & Architecture
Technical Product & Program Management
$157k - $175k/yr
Remote (US)
Master's degree
10,000+

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Chamberlain Group
Software Product Manager, AI (Remote, US)
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Chamberlain Group
Added 2d ago
Software Product Manager, AI (Remote, US)
Chamberlain Group
Illinois
Project Management
Solutions Engineering & Architecture
Technical Program Management
$159k - $268k/yr
Remote (US)
Master's degree in business administration
1,001-5,000

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See All 207+ Remote Senior AI Software Engineer Jobs

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Remote Senior AI Software Engineer Job Market

Who's Hiring

  • CVS Health
    CVS Health51
  • A
    Advanced Monitored Caregiving24
  • Serko
    Serko4
  • Aledade
    Aledade4
  • GitHub
    GitHub3

Top Industries Hiring

  • Healthcare & Medical Services49
  • Technology & Software15
  • Consulting & Professional Services6
  • Education2
  • Insurance2

What Employers Look For

The qualifications that appear most often in remote senior AI software engineer jobs.

  • Advanced degree or equivalent experience in computer science, machine learning, or a related field
  • Production experience designing, training, and deploying large-scale machine learning models
  • Proficiency in Python and at least one deep learning framework such as PyTorch or TensorFlow
  • Hands-on experience with cloud ML platforms including AWS SageMaker, Google Vertex AI, or Azure ML
  • Demonstrated ability to lead technical projects and mentor junior engineers across the AI stack
  • Familiarity with MLOps tooling, model monitoring, and CI/CD pipelines for ML systems

Tips for Your Remote Senior AI Software Engineer Job Search

Show async collaboration in your portfolio

Remote teams want evidence you can drive complex AI projects without daily standups. Include written design documents, model cards, or GitHub READMEs that explain your decision-making process. Clear async documentation signals you can function as a senior contributor on a distributed team.

Apply early to remote roles that fit

Migrate Mate lists remote senior ai software engineer openings from across the U.S. in one place, so you can find roles that match your stack and apply directly without sorting through location-filtered noise. Early applications on new postings consistently get more recruiter attention.

Highlight distributed tooling experience upfront

Call out your fluency with remote engineering tools, such as Weights and Biases for experiment tracking, Notion or Confluence for async documentation, and cloud platforms like AWS SageMaker or GCP Vertex AI, early in your resume summary. Remote hiring managers look for this before reading the rest.

Prepare for asynchronous technical interviews

Many remote-first companies use take-home coding assessments or recorded video interviews instead of live coding rounds. Practice writing thorough explanations alongside your code, since remote employers evaluate how clearly you articulate model choices and tradeoffs in writing, not just whether your solution runs.

Remote Senior AI Software Engineer Jobs: Frequently Asked Questions

How do I get a remote senior ai software engineer job?

Target remote-first companies and distributed engineering teams that already operate asynchronously, since those employers are best set up for senior ai software engineers working outside a central office. Remote hiring managers screen heavily for self-direction, clear written communication, and the ability to document technical decisions without hand-holding. Strong GitHub contributions, published model work, or a portfolio showing end-to-end AI system ownership give you a real edge over candidates with similar credentials.

Which companies hire remote senior ai software engineers?

Remote senior ai software engineer roles are posted by CVS Health, Advanced Monitored Caregiving, and Serko and others right now, based on current remote listings on Migrate Mate as of August 2026. Remote-first software companies, AI-focused startups, and distributed teams in fintech, healthcare technology, and enterprise SaaS are among the most consistent hirers of senior ai software engineers in fully remote roles.

Can you get a remote senior ai software engineer job with no experience?

Yes, but remote entry-level positions for senior ai software engineers are rare, because distributed teams expect engineers to work independently from day one with minimal in-person guidance. Candidates without formal experience can show open-source AI contributions, personal or academic projects with documented results, and evidence of async collaboration. Remote-friendly AI consultancies and early-stage startups are more likely to take a chance on self-taught engineers who can demonstrate real output.

Do you need a degree for remote senior ai software engineer jobs?

Not always. Many remote employers care more about demonstrated skills, a strong portfolio of deployed models, and the ability to communicate technical reasoning in writing than about formal credentials. That said, roles involving research or regulated industries such as healthcare AI and finance often list a relevant degree as a requirement. Showing real project work, published results, or open-source contributions can offset the absence of a degree at many companies.

Which industries hire the most remote senior ai software engineers?

Most remote senior ai software engineer openings sit in Healthcare & Medical Services, Technology & Software, and Consulting & Professional Services, per current remote listings on Migrate Mate as of August 2026. Those sectors rely on distributed engineering teams building AI-powered products and internal tooling, making them natural fits for senior ai software engineers who work remotely.

See All 207+ Remote Senior AI Software Engineer Jobs

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