Research Operations Manager Jobs
Research Operations Manager jobs are open across academia, biotech, healthcare, government, and technology, from coordinator-level to senior and director, with specializations in clinical research operations, grants and compliance management, and research program administration. Scan the live roles below and apply to whichever ones fit.
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At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development.
Days Onsite: Monday, Tuesday, & 1 other day (Hybrid) - Training will be onsite for 5 days / week
Summary:
The Research Associate 2, Operations Sustaining will provide operational and technical support for clinical lab products with focus on NeXT Personal Dx, Personalis' ultrasensitive molecular residual disease assay. The role involves partnering with a cross-functional team to triage and resolve order and sample related issues and support process improvement and scalability opportunities.
Responsibilities:
Participate in clinical laboratory sustaining support activities, including but not limited to tracking clinical sample and pipeline issues, troubleshooting, and documenting root cause and resolution.
Follow written procedure to update sample status and workflow to unblock stalled samples or address special sample movement requests.
Collaborate with lab operations, client experience, clinical software, data management, pipeline, and quality teams to address sample processing or pipeline failures and customer requests.
Partner with cross-functional teams to implement workflow improvements to support product growth.
Additional responsibilities may include remote weekend lab sustaining support.
Education & Experience:
A Bachelor's degree in a molecular biology or related field with a minimum of 3 years of relevant experience; or a master's degree and 1 or more years of relevant experience.
Working knowledge in Next Generation Sequencing technology, LIMS, and SFDC. Experience with molecular residual disease assay is a plus.
Familiarity with operations of high throughput clinical laboratory including sample accessioning, sample processing, pipeline analysis, and report release.
Highly organized and systematic, with superb attention to detail and the ability to prioritize and complete tasks with a high degree of accuracy.
Demonstrated quick learner and skilled in analytical thinking, utilizing data to drive decisions.
The hiring range for this position is $84,000 to $105,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.
Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.
Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.
Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)
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Research Operations Manager Jobs by Experience Level
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Find JobsResearch Operations Manager Job Market
Who's Hiring
- Systems Planning and Analysis, Inc. (SPA)12

- Booz Allen Hamilton9

- Trinzic7
- DoorDash7

- Lockheed Martin7

Top Industries Hiring
- Education
- Healthcare & Medical Services
- Technology & Software
- Consulting & Professional Services
- Science & Research
What Employers Look For
The qualifications that appear most often in research operations manager jobs.
- Bachelor's degree in a scientific, public health, business, or related field
- Experience managing research projects, grants, or clinical study operations
- Familiarity with IRB submission processes and research compliance requirements
- Proficiency with project management tools and research administration platforms
- Demonstrated ability to coordinate cross-functional teams and external partners
- Strong written communication skills for reporting, protocols, and stakeholder updates
Tips for Your Research Operations Manager Job Search
Tailor your resume to research infrastructure
Highlight your experience coordinating IRB submissions, managing grant lifecycles, or overseeing multi-site study logistics. Hiring managers scan for evidence you've kept complex research workflows on track, not just that you've worked near a research team.
Distinguish operations from administration in your materials
Many applicants blur the line between administrative support and true operations ownership. Use your resume and cover letter to show you've built or improved systems, managed budgets, and held accountability for timelines, not just scheduled meetings or processed paperwork.
Apply early to roles that fit
Migrate Mate lists research operations manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Target postings that name your research domain
Filter for roles that specify your domain, whether clinical, social science, environmental, or translational research. Employers in those verticals want someone fluent in domain-specific compliance frameworks, and a targeted application signals exactly that alignment.
Prepare a process improvement example for every interview
Interviewers for operations roles almost always ask what you've fixed or built from scratch. Walk in with a concrete story about a bottleneck you identified, the change you implemented, and the measurable outcome, specific to a research setting.
Negotiate scope alongside compensation
When you receive an offer, ask for clarity on budget authority, team size, and whether the role owns vendor relationships or just coordinates them. Scope defines your ability to deliver results, and misaligned expectations are a leading reason research operations managers leave within a year.
Research Operations Manager Jobs: Frequently Asked Questions
Which companies are hiring the most research operations managers?
Systems Planning and Analysis, Inc. (SPA), Booz Allen Hamilton, and Trinzic are hiring the most research operations managers right now, with openings concentrated in Virginia, California, and Maryland, based on current listings on Migrate Mate as of November 2026. Academic medical centers, life sciences companies, and large government contractors consistently represent the highest volume of postings.
How many research operations manager jobs are remote?
About 50% of research operations manager openings are fully remote or hybrid as of November 2026, with remote availability highest in grants management, research program coordination, and policy-focused roles. Positions tied to active laboratory oversight, clinical site management, or hands-on participant coordination are more likely to require on-site presence at least part of the week.
How do you become a research operations manager?
Start by building direct experience in a research environment, whether as a coordinator, analyst, or project administrator on a funded study or research program. Develop fluency in grants administration, IRB or regulatory processes, and research compliance. Progress into roles with budget responsibility and cross-functional ownership, then pursue a senior coordinator or associate manager title before moving into a full research operations manager role.
Can you get hired as a research operations manager with little experience?
Some employers post research operations manager roles that are realistic entry points if you have two to three years of project coordination experience in a research-adjacent setting, such as a clinical trial unit, university research office, or public health organization. Focusing your application on organizations that frame the role as a growth position rather than a senior leadership seat gives you a better shot when your experience is still building.
What does the research operations manager interview process look like?
Most employers run a phone screen focused on your background in research coordination or program management, followed by a panel interview with research leadership, finance, and sometimes faculty or principal investigators. Expect behavioral questions about managing competing deadlines, compliance challenges, and stakeholder conflicts. Some organizations add a practical exercise, such as drafting a project plan or reviewing a mock grant timeline, before extending an offer.
Where can I find and apply to research operations manager jobs?
You can find and apply to research operations manager jobs on Migrate Mate, which lists current openings from across the United States. Search for roles that match your domain and experience level, then apply directly to each listing that fits.
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