Research Scientist Jobs in Chicago, IL
Research Scientist jobs in Chicago are concentrated in the Illinois Medical District, Hyde Park, and the Near North Side, with strong demand across life sciences, pharmaceuticals, and academic research. Employers hiring right now include Rush University Medical Center, Northwestern University, and Tempus. Scan the live roles below and apply to whichever ones fit.
Find Research Scientist JobsOverview
Showing 5 of 31+ Research Scientist jobs
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
About Tempus and the Outcomes Research Team
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus’ proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
The Outcomes Research team partners with external Pharma, biotech, and academic institutions to provide best-in-class data, analysis, and methodological guidance for Tempus’s real-world data (RWD) offering. We are seeking a highly motivated and capable Sr. Data Scientist with extensive experience in the design and analysis of pharmacoepidemiologic and health economic outcomes research (HEOR) studies.
Responsibilities:
- Lead and execute HEOR and real-world evidence (RWE) projects (e.g., outcomes analysis, treatment patterns, healthcare resource utilization) with external Pharma, academic, and other partners.
- Represent the Outcomes Research function and collaborate with internal and external stakeholders in the design, analysis, interpretation, and publication of real-world studies.
- Work on complex problems, exercising judgment in selecting and adapting appropriate epidemiologic and health economic methodologies.
- Partner with interdisciplinary groups of scientists, engineers, and product developers to translate research into clinically actionable insights for our clients.
- Stay current with the latest methodological advances in RWE, including causal inference and pharmacoepidemiologic methods.
- Build analytical infrastructure, including reusable code, templates, and workflows that improve speed and quality across engagements.
- Comply with all applicable regulations, Tempus data governance, and company procedures related to real-world data use and reporting.
Required Qualifications:
- Advanced degree (Master’s with 5+ years experience, PhD with 3+ years experience, or Bachelor’s with 8+ years experience) in data science, bioinformatics, biostatistics, epidemiology, public health, or a related quantitative field.
- Demonstrated computational skills using R and SQL, specifically applied to large-scale healthcare datasets.
Preferred Qualifications:
- Strong data manipulation and analytical skills tailored to observational/real-world data.
- Deep familiarity with HEOR and RWE methodologies, including approaches to address confounding (e.g., propensity score matching, weighting, inverse probability of treatment weighting).
- Experience analyzing large, complex real-world datasets, such as administrative claims, electronic health records (EHR), and/or clinico-genomic databases.
- Strong communication and presentation skills with the ability to translate complex methodologies and findings for non-technical stakeholders.
- Self-driven mindset with demonstrated ability to tackle ambiguous problems and work effectively in interdisciplinary teams.
- Experience with time-to-event analysis and survival methodologies.
- Experience working in oncology and/or analyzing outcomes related to cancer genetics, immunology, or molecular biology.
- Collaborative working style, eagerness to learn, and high-integrity work ethic.
- Sharp attention to detail and a passion for delivering high-quality, timely analytics.
- Ability to draw appropriate inferences based on study design and explicitly assess and communicate study limitations.
Nice to Have:
- Experience with version control (e.g., Git) and software testing or validation processes.
- Experience working in oncology Phase II–IV clinical trials and/or analysis of RWD studies (e.g., claims, EHR, registry data sources).
- Hands-on experience contributing to regulatory submissions to the FDA or other health authorities.
- Experience supporting data science teams in model building and validation, including feature engineering and performance assessment.
- Client-facing or consulting experience and comfort presenting results and recommendations to external stakeholders.
Remote US: $100,000-$160,000
NYC/SF: $115,000-$175,000
The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
About Us
Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics.
We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives.
Why Work Here?
We’re looking for people who can change the world.
Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.
Passionate about precision medicine and advancing the healthcare industry?
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
About Tempus and the Outcomes Research Team
Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus’ proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.
The Outcomes Research team partners with external Pharma, biotech, and academic institutions to provide best-in-class data, analysis, and methodological guidance for Tempus’s real-world data (RWD) offering. We are seeking a highly motivated and capable Sr. Data Scientist with extensive experience in the design and analysis of pharmacoepidemiologic and health economic outcomes research (HEOR) studies.
Responsibilities:
- Lead and execute HEOR and real-world evidence (RWE) projects (e.g., outcomes analysis, treatment patterns, healthcare resource utilization) with external Pharma, academic, and other partners.
- Represent the Outcomes Research function and collaborate with internal and external stakeholders in the design, analysis, interpretation, and publication of real-world studies.
- Work on complex problems, exercising judgment in selecting and adapting appropriate epidemiologic and health economic methodologies.
- Partner with interdisciplinary groups of scientists, engineers, and product developers to translate research into clinically actionable insights for our clients.
- Stay current with the latest methodological advances in RWE, including causal inference and pharmacoepidemiologic methods.
- Build analytical infrastructure, including reusable code, templates, and workflows that improve speed and quality across engagements.
- Comply with all applicable regulations, Tempus data governance, and company procedures related to real-world data use and reporting.
Required Qualifications:
- Advanced degree (Master’s with 5+ years experience, PhD with 3+ years experience, or Bachelor’s with 8+ years experience) in data science, bioinformatics, biostatistics, epidemiology, public health, or a related quantitative field.
- Demonstrated computational skills using R and SQL, specifically applied to large-scale healthcare datasets.
Preferred Qualifications:
- Strong data manipulation and analytical skills tailored to observational/real-world data.
- Deep familiarity with HEOR and RWE methodologies, including approaches to address confounding (e.g., propensity score matching, weighting, inverse probability of treatment weighting).
- Experience analyzing large, complex real-world datasets, such as administrative claims, electronic health records (EHR), and/or clinico-genomic databases.
- Strong communication and presentation skills with the ability to translate complex methodologies and findings for non-technical stakeholders.
- Self-driven mindset with demonstrated ability to tackle ambiguous problems and work effectively in interdisciplinary teams.
- Experience with time-to-event analysis and survival methodologies.
- Experience working in oncology and/or analyzing outcomes related to cancer genetics, immunology, or molecular biology.
- Collaborative working style, eagerness to learn, and high-integrity work ethic.
- Sharp attention to detail and a passion for delivering high-quality, timely analytics.
- Ability to draw appropriate inferences based on study design and explicitly assess and communicate study limitations.
Nice to Have:
- Experience with version control (e.g., Git) and software testing or validation processes.
- Experience working in oncology Phase II–IV clinical trials and/or analysis of RWD studies (e.g., claims, EHR, registry data sources).
- Hands-on experience contributing to regulatory submissions to the FDA or other health authorities.
- Experience supporting data science teams in model building and validation, including feature engineering and performance assessment.
- Client-facing or consulting experience and comfort presenting results and recommendations to external stakeholders.
Remote US: $100,000-$160,000
NYC/SF: $115,000-$175,000
The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.
Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.
We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
About Us
Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics.
We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives.
Why Work Here?
We’re looking for people who can change the world.
Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.
See All 31 Research Scientist Jobs in Chicago
Find roles in Chicago that match your experience and apply in just a few clicks.
Find Research Scientist JobsResearch Scientist Job Market in Chicago
Who's Hiring
Top Industries Hiring
- Education
- Healthcare & Medical Services
Research Scientist Jobs in Chicago: Frequently Asked Questions
How do I get a research scientist job in Chicago?
Target the clusters where Chicago research hiring is densest: the Illinois Medical District for biomedical and clinical research, Hyde Park for academic and university-affiliated roles, and the North Shore corridor for pharmaceutical and biotech labs. Candidates who can show peer-reviewed publications, hands-on lab methodology, or cross-functional project experience stand out. Networking through the Chicago Biotech Network and university research centers also opens doors that posted listings don't.
Which companies hire research scientists in Chicago?
Employers hiring research scientists in Chicago right now include Rush University Medical Center, Northwestern University, and Tempus, based on current listings on Migrate Mate as of November 2026. Chicago's hiring mix leans heavily toward academic medical centers, pharmaceutical manufacturers, and mid-size biotech firms with R&D operations in the metro area.
Are there remote research scientist jobs in Chicago?
Yes, though it depends heavily on the role: computational, data-driven, and regulatory research positions are far more remote-friendly than bench or clinical research, which requires on-site lab access. About 60% of research scientist openings tied to Chicago are remote or hybrid as of November 2026, skewing toward bioinformatics, health economics, and research analytics roles rather than wet-lab positions.
How can I get a research scientist job in Chicago with little or no experience?
The most realistic entry path in Chicago is a research associate or lab technician role at one of the city's academic medical centers, such as those affiliated with Rush University Medical Center or Northwestern Memorial. Many Chicago biotech startups and contract research organizations also hire junior scientists for defined project work, where you can build a publication record quickly. A master's degree with a strong thesis project, or a postdoctoral stint at a Chicago university, is the clearest bridge to a full scientist title.
Which industries hire the most research scientists in Chicago?
Chicago research scientist roles concentrate in Education and Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. Chicago's position as a major academic medical hub and its growing North Shore pharmaceutical corridor drive consistent demand across those sectors year-round.
Related Jobs in Illinois
See All 31 Research Scientist Jobs in Chicago
Find roles in Chicago that match your experience and apply in just a few clicks.
Find Research Scientist Jobs