Principal Scientist Jobs in Illinois
Principal Scientist jobs in Illinois are concentrated in pharmaceutical research, biotechnology, agricultural science, and materials chemistry, with demand at every level from early-career researcher through senior principal scientist. Chicago, the North Shore suburbs of Gurnee and Waukegan, and the Deerfield-Lake County research corridor are the busiest hiring areas, anchored by long-established employers such as AbbVie, Baxter International, and Archer Daniels Midland. The most sought-after specializations include oncology drug discovery, analytical chemistry, and agricultural biotechnology. Find a role that fits below and apply directly.
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At Tate & Lyle, our purpose is simple: Transforming Lives Through the Science of Food. We partner with leading food and beverage brands around the world to create healthier, tastier and more sustainable products that consumers love. Backed by more than 165 years of innovation, our people are passionate about making a positive difference for customers, communities and the planet.
If you're looking to be part of a purpose-led organization where your work can have a real impact, read on to learn more about this opportunity and how you can help shape the future of food.
About the Role
We are looking for an Associate Principal Scientist in Analytical Material Science to strengthen our team and expertise in material characterization and ingredient functionality. This role focuses on understanding how microstructure and physical properties drive product texture, sensory perception, stability, and performance. Using rheology, tribology, microscopy, and advanced data science, you will transform complex experimental data into actionable insights that accelerate innovation. This role balances hands-on advanced laboratory analysis with cross-functional project leadership.
Beyond technical excellence, you will bring a strong customer service mindset, working closely with internal and external stakeholders to understand scientific and business needs, provide clear recommendations, and deliver high-quality analytical insights that enable successful product development and customer solutions. Success in this role requires the ability to combine scientific rigor, effective communication, and customer-focused problem solving.
Key Responsibilities
- Lead characterization of ingredients and multiphase food systems using advanced material science techniques, including rheology, tribology, microscopy, particle characterization and related material science techniques.
- Utilize and maintain high-end physical and chemical profiling tools such as rheometers, tribometers, particle size analyzers and microscopy (SEM/optical microscopes).
- Design and execute experiments to understand structure-function relationships and the impact of ingredient composition, processing, and formulation on product performance.
- Develop, validate, and optimize analytical methods and characterization workflows.
- Apply DoE, multivariate statistics, and data science tools to analyze complex datasets and identify key drivers of ingredient functionality.
- Build predictive models linking material properties and microstructure to texture, sensory attributes, stability, and processability.
- Partner closely with Product Development, Application Science, Process Engineering, Regulatory, and Sensory teams to solve complex formulation challenges and scale up pilot operations.
- Act as the subject matter expert for technical sales and customer-facing teams, providing scientific guidance, supporting customer engagements, and translating complex material science data into actionable insights and customer-focused solutions.
- Mentor junior scientists and contribute to the growth of analytical and material science capabilities.
- Communicate technical findings effectively through presentations, reports, scientific publications, and stakeholder discussions.
Key Competencies
- Scientific curiosity and problem-solving mindset
- Strong analytical and critical thinking skills
- Data science and statistical modeling capabilities
- Excellent written and verbal communication skills
- Ability to influence and collaborate across functions
- Technical leadership and mentoring capability
- Project management and prioritization skills
- Ability to translate complex scientific insights into business impact
Qualifications
- PhD in Material Science, Food Science, Polymer Science, Analytical Chemistry, or a related discipline.
- 3+ years (or 6+ years with a Master’s degree) of experience in industrial or applied research within food ingredients, food technology, biomaterials, or related sectors.
- Proven track record in food physics, soft matter rheology, and the structural properties of proteins, carbohydrates, and lipids.
- Proficient in Design of Experiments (DoE) and statistical software platforms (e.g., Minitab, Python, R, or JMP) for multivariate data analysis.
- Preferably knowledgeable in analytical chemistry, such as mass spectrometry, chromatography and other techniques.
What we can offer you
Tate & Lyle complies with all local/state regulations requiring salary range transparency. When determining final compensation, we take into consideration: skillset, job scope, knowledge, prior experience, cost of living, market data, budget availability, and other factors as permitted by law.
The salary range for this position is: $71,000 - $104,000.
In addition to competitive pay, we offer a comprehensive Total Rewards package that includes but is not limited to:
Medical, Dental, Vision coverages
Paid time off package, including vacation, sick time, and 16 weeks of paid parental leave
401K with company match
Company paid life insurance
Additional benefits at not cost to employee such as: Lifestyle Spending Account, Identity Theft protection, Employee Assistance Program, telemedicine and more!
In addition to your Total Rewards, culture and ED&I are very important to Tate & Lyle. We offer multiple Employee Resource Groups (ERGs) that support various communities.
#LI-RF1
California Consumer Privacy Act ("CCPA")
The Company is committed to complying with the California Consumer Privacy Act (“CCPA”) and all data privacy and laws in the jurisdictions in which it recruits and hires employees. We collect the following categories of personal information for the purpose of hiring the best qualified applicants and to comply with applicable employment laws: Name and contact information; Job preference and work availability; Social Security Number and/or other identification information; Education and qualifications; Employment history and experience; Military service; Reference and background check information, including relevant criminal history and credit history; Social media information; Pre-employment test results; Post-offer medical examination information and results, including drug test results; Voluntary self-disclosure information regarding minority, veteran, and disability status; and Information provided by you during the hiring process.
Tate & Lyle is an equal opportunity employer, committed to the strength of an inclusive workforce.
See All 25 Principal Scientist Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
Find Principal Scientist JobsPrincipal Scientist Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Principal Scientist Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring
- AbbVie15

- Kraft Heinz3

- Okta1

- Tempus AI1

- Capital One1

Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Food & Beverage
- Agriculture & Farming
- Banking & Financial Services
What Illinois Employers Look For
The qualifications that appear most often in principal scientist jobs across Illinois.
- Ph.D. in a relevant scientific discipline such as chemistry, biology, or biochemistry
- Minimum five to eight years of post-doctoral or industry research experience in Illinois-dominant sectors
- Demonstrated ability to lead multi-disciplinary research teams and mentor junior scientists
- Expertise in experimental design, data analysis, and peer-reviewed publication or patent authorship
- Proficiency with regulatory frameworks relevant to pharmaceutical or agricultural product development
- Strong cross-functional collaboration skills with clinical, regulatory, and commercial teams
Principal Scientist Jobs in Illinois: Frequently Asked Questions
How do you become a principal scientist in Illinois?
Becoming a principal scientist in Illinois typically requires an advanced degree, usually a Ph.D., in a field aligned with the target industry such as chemistry, molecular biology, or materials science. Illinois does not issue a state license specific to the principal scientist title, so hiring decisions center on advanced education, peer-reviewed research output, and progressively senior laboratory or program leadership experience gained at Illinois research institutions or industry employers.
Which companies hire principal scientists in Illinois?
Employers hiring principal scientists in Illinois right now include AbbVie, Kraft Heinz, and Okta, based on current listings on Migrate Mate as of August 2026. Illinois's dense concentration of pharmaceutical headquarters and agricultural science companies along the I-294 corridor and Lake County means principal scientist openings appear year-round across multiple disciplines.
Which Illinois cities have the most principal scientist jobs?
North Chicago, Chicago, and Glenview have the most principal scientist openings in Illinois. Chicago drives volume through its large hospital systems and university-affiliated research centers, while suburban Lake County and the North Shore corridor concentrate pharmaceutical and biotech postings because AbbVie, Baxter, and several specialty drug companies maintain major research campuses there.
Are there remote principal scientist jobs in Illinois?
Yes, but they're rare. About 50% of principal scientist openings tied to Illinois are remote or hybrid as of August 2026, reflecting the hands-on laboratory nature of most roles in the state's pharmaceutical and biotech sectors. The sub-functions most likely to offer remote flexibility are computational biology, bioinformatics, and regulatory or scientific affairs roles that do not require bench work.
How can I get hired as a principal scientist in Illinois with little or no experience?
The most realistic entry path is a post-doctoral fellowship at an Illinois research university such as the University of Illinois Urbana-Champaign or Northwestern University, which pipeline directly into industry roles. Large Illinois employers including AbbVie and Baxter run structured early-talent programs that recruit from these institutions. Candidates can also move laterally from research associate or scientist roles into principal scientist tracks by building a record of independent project ownership and publication.
Where can I find and apply to principal scientist jobs in Illinois?
You can find and apply to principal scientist jobs in Illinois on Migrate Mate, which lists current Illinois openings across pharmaceutical, biotech, agricultural science, and materials research employers. Find the roles that fit your background and apply directly from the listings on this page.
See All 25 Principal Scientist Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
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