Entry Level Screening Officer Jobs
New grad screening officer jobs welcome recent graduates and entry level candidates with zero to two years of experience, where a strong internship background or hands-on training can matter more than a lengthy resume. Most openings are on-site roles across Healthcare & Medical Services, Education, and Science & Research, with employers like Guardant Health, Saint Alphonsus Health System, and City of Hope hiring at this level now.
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Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
A Research Assistant II position is available within the High Throughput Screening (HTS) Core. The HTS Core supports early-stage drug discovery through assay development and optimization, high-throughput small-molecule screening, hit identification and validation, and lead optimization. The Core provides investigators with access to automated screening capabilities, a collection of more than 250,000 small molecules, and scientific expertise in biochemical and cell-based assay development.
We are seeking a highly motivated and collaborative research professional with experience in cell biology, biochemistry, assay development, and/or drug discovery. You will work closely with investigators and support the development, optimization, execution of small molecule screening, hit validation, and quantitative data analysis. The position will involve extensive hands-on laboratory work and close collaboration with HTS Core staff and investigators across multiple drug-discovery and translational research projects.
In addition to traditional HTS approaches, the HTS Core also involves advanced translational screening technologies, including 3D/organoid models imaging and profiling, high-content imaging and image-based phenotypic screening. Experience in one or more of these emerging areas would be highly valued.
As a successful candidate you will:
- Develop, optimize, validate, and miniaturize biochemical and cell-based assays for drug discovery and small-molecule screening.
- Design and execute high-throughput and medium-throughput screening campaigns, including primary screening, hit confirmation, concentration-response studies, counter-screens, and orthogonal/secondary validation assays.
- Utilize and support laboratory automation, liquid handling, multimode detection, and other screening technologies to establish efficient and reproducible drug-discovery workflows.
- Develop and apply high-content imaging and image-based phenotypic assays, including live-cell and multiparametric imaging.
- Manage multiple collaborative projects while maintaining high standards for experimental rigor, reproducibility, data integrity, documentation, and timely project execution.
- Develop and standardize protocols, provide technical guidance and training, and contribute to a collaborative multidisciplinary research environment.
Your qualifications should include:
- Bachelor’s degree. Masters degree preferred
- 2+ years of related experience with a Bachelor’s degree or 1+ year related experience with a Master’s degree.
- Hands-on experience with biochemical and cell-based assay development, optimization, validation, and troubleshooting, including protein biochemical and reporter assays.
- Experience with mammalian cell culture and complex in vitro models, including primary cells, organoids, spheroids, 3D cultures, patient-derived models, and co-culture systems.
- Experience with high-throughput screening (HTS), compound screening, hit validation, lead-optimization workflows, and automated liquid-handling systems.
- Experience with high-content and live-cell imaging, phenotypic screening, and quantitative image analysis.
- Demonstrated ability to independently execute experiments, analyze data, troubleshoot, and maintain accurate, reproducible records, with proficiency in GraphPad, LIMS, and Microsoft Office.
- Strong organizational, communication, and collaboration skills, with the ability to manage multiple priorities, meet deadlines, work effectively across scientific teams, and write and follow protocols.
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, please CLICK HERE.
Please note: City of Hope is committed to a safe and transparent hiring experience. Please be aware that scammers may attempt to impersonate our organization through fake job postings, emails or interviews.
- Apply only through our official website or trusted partner platforms.
- City of Hope will never request payment or fees at any stage of the hiring process.
- We will not request sensitive personal or financial information prior to the acceptance of a formal offer.
- All communications will come from official@coh.org email addresses.
- Interviews are conducted only through approved, professional channels.
- Be cautious of unsolicited communications, urgent requests or opportunities that seem inconsistent with standard hiring practices.
- If you receive any suspicious communication, please report it to careers@coh.org.
Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
A Research Assistant II position is available within the High Throughput Screening (HTS) Core. The HTS Core supports early-stage drug discovery through assay development and optimization, high-throughput small-molecule screening, hit identification and validation, and lead optimization. The Core provides investigators with access to automated screening capabilities, a collection of more than 250,000 small molecules, and scientific expertise in biochemical and cell-based assay development.
We are seeking a highly motivated and collaborative research professional with experience in cell biology, biochemistry, assay development, and/or drug discovery. You will work closely with investigators and support the development, optimization, execution of small molecule screening, hit validation, and quantitative data analysis. The position will involve extensive hands-on laboratory work and close collaboration with HTS Core staff and investigators across multiple drug-discovery and translational research projects.
In addition to traditional HTS approaches, the HTS Core also involves advanced translational screening technologies, including 3D/organoid models imaging and profiling, high-content imaging and image-based phenotypic screening. Experience in one or more of these emerging areas would be highly valued.
As a successful candidate you will:
- Develop, optimize, validate, and miniaturize biochemical and cell-based assays for drug discovery and small-molecule screening.
- Design and execute high-throughput and medium-throughput screening campaigns, including primary screening, hit confirmation, concentration-response studies, counter-screens, and orthogonal/secondary validation assays.
- Utilize and support laboratory automation, liquid handling, multimode detection, and other screening technologies to establish efficient and reproducible drug-discovery workflows.
- Develop and apply high-content imaging and image-based phenotypic assays, including live-cell and multiparametric imaging.
- Manage multiple collaborative projects while maintaining high standards for experimental rigor, reproducibility, data integrity, documentation, and timely project execution.
- Develop and standardize protocols, provide technical guidance and training, and contribute to a collaborative multidisciplinary research environment.
Your qualifications should include:
- Bachelor’s degree. Masters degree preferred
- 2+ years of related experience with a Bachelor’s degree or 1+ year related experience with a Master’s degree.
- Hands-on experience with biochemical and cell-based assay development, optimization, validation, and troubleshooting, including protein biochemical and reporter assays.
- Experience with mammalian cell culture and complex in vitro models, including primary cells, organoids, spheroids, 3D cultures, patient-derived models, and co-culture systems.
- Experience with high-throughput screening (HTS), compound screening, hit validation, lead-optimization workflows, and automated liquid-handling systems.
- Experience with high-content and live-cell imaging, phenotypic screening, and quantitative image analysis.
- Demonstrated ability to independently execute experiments, analyze data, troubleshoot, and maintain accurate, reproducible records, with proficiency in GraphPad, LIMS, and Microsoft Office.
- Strong organizational, communication, and collaboration skills, with the ability to manage multiple priorities, meet deadlines, work effectively across scientific teams, and write and follow protocols.
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, please CLICK HERE.
Please note: City of Hope is committed to a safe and transparent hiring experience. Please be aware that scammers may attempt to impersonate our organization through fake job postings, emails or interviews.
- Apply only through our official website or trusted partner platforms.
- City of Hope will never request payment or fees at any stage of the hiring process.
- We will not request sensitive personal or financial information prior to the acceptance of a formal offer.
- All communications will come from official@coh.org email addresses.
- Interviews are conducted only through approved, professional channels.
- Be cautious of unsolicited communications, urgent requests or opportunities that seem inconsistent with standard hiring practices.
- If you receive any suspicious communication, please report it to careers@coh.org.
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Entry Level Screening Officer Jobs: Frequently Asked Questions
How do I get an entry level screening officer job?
Focus on any hands-on experience that shows attention to detail and ability to follow procedures, such as security internships, volunteer work, or customer-facing roles. Employers at this level typically look for reliability, communication skills, and a willingness to complete required certifications. Highlighting relevant coursework, training programs, or a background in public safety or customer service gives entry level candidates a clear edge.
Which companies hire entry level screening officers?
Companies hiring entry level screening officers right now include Guardant Health, Saint Alphonsus Health System, and City of Hope, based on current listings on Migrate Mate as of November 2026. Hiring at this level comes from a broad range of organizations, including government contractors, transportation hubs, healthcare facilities, and private security firms that regularly onboard candidates with little or no prior experience.
Are there remote entry level screening officer jobs?
Yes, though most screening officer roles are on-site by nature given the hands-on requirements of the work. About 43% of entry level screening officer openings are remote or hybrid as of November 2026, and those tend to involve administrative, intake, or coordination functions within a screening program rather than direct physical screening duties.
Are these new grad screening officer jobs?
Yes, many of these openings are new grad and junior roles that explicitly welcome recent graduates and candidates with limited work history. A new grad friendly posting typically requires zero to two years of experience, accepts internships or related training in place of full-time work, and does not list advanced certifications as a strict requirement. Entry level screening officer jobs are a practical first step for anyone breaking into the field.
Which industries hire the most entry level screening officers?
Entry Level screening officer roles concentrate in Healthcare & Medical Services, Education, and Science & Research, based on current listings on Migrate Mate as of November 2026. These sectors drive consistent demand at the entry level because they require ongoing screening operations, face high staff turnover, and regularly recruit candidates who can be trained on the job without extensive prior experience.