Senior Clinical Trial Manager Jobs in New Jersey
Senior Clinical Trial Manager jobs in New Jersey are among the most active in the country, concentrated in the pharmaceutical, biotechnology, and medical device sectors that define the state's life sciences corridor. Most hiring is in and around Bridgewater, Parsippany, and Princeton, where companies like Johnson and Johnson, Merck, and Novartis maintain significant operations. The most consistent openings are in oncology, rare disease, and late-phase trials. Find a role that fits below and apply directly.
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Showing 5 of 15+ Senior Clinical Trial Manager jobs
Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.
Legend Biotech is seeking a Senior Clinical Trial Associate as part of the Clinical Operations team based in Somerset, NJ.
Role Overview
We are seeking a highly skilled and motivated Senior Clinical Trial Associate (Sr. CTA) to join our growing Clinical Operations team to support early-stage clinical development. The Sr. CTA will play a critical role in the execution of complex Phase I/II CAR-T oncology clinical trials by providing high-quality operational, administrative, and coordination support.
The ideal candidate will have substantial experience in clinical trial operations and administration, with a strong understanding of clinical trial processes, regulatory requirements, and GCP. This role is critical to ensuring the efficient execution of clinical trials, maintaining regulatory compliance, and providing operational support to cross-functional study teams.
Key Responsibilities
- Provide cross-functional administrative and operational support for study team meetings, advisory boards, investigator meetings, and other study-related forums.
- Support Senior Clinical Trial Managers in the day-to-day execution of complex Phase I and Phase II CAR-T oncology trials, ensuring all activities are conducted in compliance with ICH-GCP and applicable regulatory requirements.
- Oversee the preparation, organization, and maintenance of trial documentation, including regulatory files, Trial Master Files (TMFs/eTMFs), and study correspondence.
- Ensure documentation is current, complete, and compliant with ICH-GCP and company SOPs.
- Assist with the planning, start-up, execution, and close-out of clinical trials, including coordination with clinical sites and support of protocol and regulatory compliance activities.
- Assist with the preparation, submission, and tracking of regulatory and IRB/IEC documents.
- Maintain working knowledge of applicable regulations and standards to support ongoing study compliance.
- Schedule and coordinate study meetings, including investigator meetings, site visits, and internal team meetings.
- Prepare meeting agendas, document minutes, track action items, and follow up to ensure timely completion.
- Assist in tracking trial progress, including site activation, enrollment, monitoring activities, and key study milestones.
- Prepare and maintain study status reports and trackers for internal and external stakeholders.
- Support data management activities, including query tracking and data reconciliation, in collaboration with Data Management.
- Serve as a key liaison between the clinical trial team, vendors, CROs, and investigational sites to ensure clear and timely communication.
- Assist with vendor oversight by tracking deliverables, timelines, and resolving operational issues.
- Proactively identify operational issues and risks, propose solutions, and escalate to the Senior Clinical Trial Manager or Clinical Operations leadership as appropriate.
- Contribute to the development and continuous improvement of clinical operations processes and best practices.
- Provide guidance and mentorship to junior CTAs, sharing best practices and contributing to team capability building.
Requirements
- Bachelor's degree in life sciences, clinical research, or a related field.
- Relevant certifications (e.g., CRC, CRA) are a plus.
- Minimum of 3–5 years of experience as a Clinical Trial Associate or in a similar clinical research role.
- Demonstrated experience supporting trial coordination, regulatory documentation, and site management activities.
- Oncology trial experience required; cell therapy and/or CAR-T experience strongly preferred.
- Strong understanding of ICH-GCP, regulatory requirements, and clinical trial processes.
- Proficiency with CTMS, eTMF, and EDC systems.
- Excellent organizational skills with the ability to manage multiple priorities in a fast-paced environment.
- Strong written and verbal communication skills.
- Detail-oriented with strong analytical and problem-solving skills.
- Ability to work independently and collaboratively within cross-functional teams.
- Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint) and familiarity with eTMF and EDC platforms.
#Li-RP1
#Li-Hybrid
Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.
Work Authorization & Employment Eligibility
Applicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.
EEO Statement
It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.
Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.
Legend Biotech is seeking a Senior Clinical Trial Associate as part of the Clinical Operations team based in Somerset, NJ.
Role Overview
We are seeking a highly skilled and motivated Senior Clinical Trial Associate (Sr. CTA) to join our growing Clinical Operations team to support early-stage clinical development. The Sr. CTA will play a critical role in the execution of complex Phase I/II CAR-T oncology clinical trials by providing high-quality operational, administrative, and coordination support.
The ideal candidate will have substantial experience in clinical trial operations and administration, with a strong understanding of clinical trial processes, regulatory requirements, and GCP. This role is critical to ensuring the efficient execution of clinical trials, maintaining regulatory compliance, and providing operational support to cross-functional study teams.
Key Responsibilities
- Provide cross-functional administrative and operational support for study team meetings, advisory boards, investigator meetings, and other study-related forums.
- Support Senior Clinical Trial Managers in the day-to-day execution of complex Phase I and Phase II CAR-T oncology trials, ensuring all activities are conducted in compliance with ICH-GCP and applicable regulatory requirements.
- Oversee the preparation, organization, and maintenance of trial documentation, including regulatory files, Trial Master Files (TMFs/eTMFs), and study correspondence.
- Ensure documentation is current, complete, and compliant with ICH-GCP and company SOPs.
- Assist with the planning, start-up, execution, and close-out of clinical trials, including coordination with clinical sites and support of protocol and regulatory compliance activities.
- Assist with the preparation, submission, and tracking of regulatory and IRB/IEC documents.
- Maintain working knowledge of applicable regulations and standards to support ongoing study compliance.
- Schedule and coordinate study meetings, including investigator meetings, site visits, and internal team meetings.
- Prepare meeting agendas, document minutes, track action items, and follow up to ensure timely completion.
- Assist in tracking trial progress, including site activation, enrollment, monitoring activities, and key study milestones.
- Prepare and maintain study status reports and trackers for internal and external stakeholders.
- Support data management activities, including query tracking and data reconciliation, in collaboration with Data Management.
- Serve as a key liaison between the clinical trial team, vendors, CROs, and investigational sites to ensure clear and timely communication.
- Assist with vendor oversight by tracking deliverables, timelines, and resolving operational issues.
- Proactively identify operational issues and risks, propose solutions, and escalate to the Senior Clinical Trial Manager or Clinical Operations leadership as appropriate.
- Contribute to the development and continuous improvement of clinical operations processes and best practices.
- Provide guidance and mentorship to junior CTAs, sharing best practices and contributing to team capability building.
Requirements
- Bachelor's degree in life sciences, clinical research, or a related field.
- Relevant certifications (e.g., CRC, CRA) are a plus.
- Minimum of 3–5 years of experience as a Clinical Trial Associate or in a similar clinical research role.
- Demonstrated experience supporting trial coordination, regulatory documentation, and site management activities.
- Oncology trial experience required; cell therapy and/or CAR-T experience strongly preferred.
- Strong understanding of ICH-GCP, regulatory requirements, and clinical trial processes.
- Proficiency with CTMS, eTMF, and EDC systems.
- Excellent organizational skills with the ability to manage multiple priorities in a fast-paced environment.
- Strong written and verbal communication skills.
- Detail-oriented with strong analytical and problem-solving skills.
- Ability to work independently and collaboratively within cross-functional teams.
- Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint) and familiarity with eTMF and EDC platforms.
#Li-RP1
#Li-Hybrid
Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.
Work Authorization & Employment Eligibility
Applicants must be authorized to work in the United States. As part of our commitment to maintaining a lawful workforce and ensuring compliance with federal employment regulations, we participate in the E-Verify program. If you are selected for employment, you will be required to complete the Form I-9 process, and your employment eligibility will be verified through E-Verify in accordance with applicable federal law. We are committed to providing a fair, transparent, and welcoming hiring experience for all candidates.
EEO Statement
It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.
See All 15 Senior Clinical Trial Manager Jobs in New Jersey
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Find JobsSenior Clinical Trial Manager Jobs by City in New Jersey
Where New Jersey roles are concentrated, by current openings.
Senior Clinical Trial Manager Job Market in New Jersey
A snapshot from current New Jersey openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Medical Devices
- Science & Research
- Technology & Software
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
What New Jersey Employers Look For
The qualifications that appear most often in senior clinical trial manager jobs across New Jersey.
- Bachelor's degree in life sciences, nursing, or a related clinical field required
- Minimum five years of clinical trial management experience across multiple phases
- Demonstrated ability to manage CRO relationships and vendor oversight independently
- Proficiency with electronic data capture systems such as Medidata Rave or Veeva Vault
- Strong knowledge of ICH-GCP guidelines and FDA regulatory requirements for clinical trials
- PMP or ACRP CCRA certification preferred by many New Jersey pharmaceutical employers
Senior Clinical Trial Manager Jobs in New Jersey: Frequently Asked Questions
How do you become a senior clinical trial manager in New Jersey?
The path to a senior clinical trial manager role in New Jersey typically starts with a bachelor's degree in a life science, pharmacy, or nursing discipline, followed by several years of hands-on clinical operations experience. New Jersey does not require a state-issued license specific to this role, but many employers prefer candidates who hold certifications from the Association of Clinical Research Professionals or the Society of Clinical Research Associates. Building experience within the state's dense pharmaceutical corridor strengthens candidacy considerably.
Which companies hire senior clinical trial managers in New Jersey?
Employers hiring senior clinical trial managers in New Jersey right now include Eikon Therapeutics, Katalyst Healthcares & Life Sciences, and Collabera, based on current listings on Migrate Mate as of August 2026. New Jersey's concentration of global pharmaceutical and biotechnology headquarters means demand is consistent across both large sponsors and contract research organizations with offices in the state.
Which New Jersey cities have the most senior clinical trial manager jobs?
Jersey City, Edison, and Gladstone account for the highest concentration of senior clinical trial manager openings in New Jersey. The Bridgewater and Parsippany areas anchor much of the hiring because of the large pharmaceutical headquarters clustered there, while Princeton draws openings tied to biotechnology research campuses and academic medical partnerships in the surrounding region.
Are there remote senior clinical trial manager jobs in New Jersey?
Yes, and more than most clinical roles, since senior clinical trial managers handle oversight, vendor management, and documentation work that translates well to remote settings. About 71% of senior clinical trial manager openings tied to New Jersey are remote or hybrid as of August 2026, reflecting the desk-heavy nature of the senior function. Protocol oversight, site communication, and regulatory writing are the responsibilities most commonly performed remotely.
How can I get hired as a senior clinical trial manager in New Jersey with little or no experience?
The most realistic entry path is through a clinical research associate or clinical trial associate role at one of the many contract research organizations operating in New Jersey, such as those with offices in Parsippany or Princeton. From there, candidates build site monitoring and protocol management experience before moving into managerial positions. Completing an ACRP or SOCRA certification early strengthens applications, and New Jersey's large pharmaceutical employers frequently post associate clinical trial manager openings that serve as a direct bridge to senior-level roles.
Where can I find and apply to senior clinical trial manager jobs in New Jersey?
You can find and apply to senior clinical trial manager jobs in New Jersey on Migrate Mate, which lists current openings in the state. Search the available roles, find the ones that match your experience and target companies, and apply directly to the employers posting them.
See All 15 Senior Clinical Trial Manager Jobs in New Jersey
Find roles in New Jersey that match your experience and apply in just a few clicks.
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