Senior Clinical Trial Manager Jobs in Massachusetts
Senior Clinical Trial Manager jobs in Massachusetts are in high demand, concentrated in the biotechnology, pharmaceutical, and academic medical center sectors, with openings ranging from newly promoted managers through veteran global trial leads. The greatest concentration of hiring is in and around Boston, Cambridge, and Worcester, where established employers like Pfizer, Biogen, and Massachusetts General Hospital Brigham run large-scale clinical operations. The most consistently sought specialties are oncology trial management, rare disease studies, and multi-site Phase II and III oversight. Find a role that fits below and apply directly.
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Showing 4 of 20+ Senior Clinical Trial Manager jobs
The Role
The Clinical Trial Manager provides clinical trial oversight to the assigned clinical trial(s) ensuring deliverables are met in terms of quality, compliance and timing. Strong vendor management is critical for this role. The position reports to the Director, Clinical Operations and is accountable to the Clinical Operations Lead for assigned studies. This role may work collaboratively on one trial or across several trials to support clinical operations activities.
Here’s What You’ll Do
- Day to day management of assigned clinical trial(s) to ensure deliverables are met in all phases of trial
- Communication to internal team members on deliverables and ensuring timelines are met
- Manage trial feasibility process
- Work closely with study Clinical Operations Lead and/or assigned Clinical Trial Manager(s) to execute clinical studies
- Drafting site materials including training, manuals and support documentation
- Monitoring of clinical data to ensure timely entry and readiness for data review meetings
- Periodic review of clinical data
- Review of clinical monitoring reports to ensure timely completion and identification of issues
- Ensure trial samples are ready to be sent to vendors in order to meet trial deliverables
- Maintain trial metrics
- Ensure trial is conducted in accordance with Moderna and ICH/GCP standards including multiple regions in global trials
- Support testing clinical trial systems/databases (i.e. UAT)
- May support additional clinical trial(s) in an unblinded Clinical Trial Manager capacity
- Develop and maintain strong, collaborative relationships with key stakeholders within Moderna
Here’s What You’ll Bring To The Table
- At least 5 five years of trial coordination experience in a clinical research and industry environment
- Advanced degree preferred or Bachelor’s in a science-based subject
- Relevant experience in global setting
- Solid understanding of drug development
- Good project management skills
- Good understanding of FDA and ICH GCP guidelines to ensure the appropriate conduct of clinical studies
- Excellent verbal and written communication skills
- Good organizational skills and attention to detail
Pay & Benefits
At Moderna, we believe that when you feel your best, you can do your best work.
That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.
- Competitive healthcare, plus voluntary benefit programs to support your unique needs
- A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
- Family planning benefits, including fertility, adoption, and surrogacy support
- Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
- Savings and investments to help you plan for the future
- Location-specific perks and extras
The salary range for this role is $109,200.00 - $174,600.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Our Working Model
As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment.
Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Accommodations
We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com.
The Role
The Clinical Trial Manager provides clinical trial oversight to the assigned clinical trial(s) ensuring deliverables are met in terms of quality, compliance and timing. Strong vendor management is critical for this role. The position reports to the Director, Clinical Operations and is accountable to the Clinical Operations Lead for assigned studies. This role may work collaboratively on one trial or across several trials to support clinical operations activities.
Here’s What You’ll Do
- Day to day management of assigned clinical trial(s) to ensure deliverables are met in all phases of trial
- Communication to internal team members on deliverables and ensuring timelines are met
- Manage trial feasibility process
- Work closely with study Clinical Operations Lead and/or assigned Clinical Trial Manager(s) to execute clinical studies
- Drafting site materials including training, manuals and support documentation
- Monitoring of clinical data to ensure timely entry and readiness for data review meetings
- Periodic review of clinical data
- Review of clinical monitoring reports to ensure timely completion and identification of issues
- Ensure trial samples are ready to be sent to vendors in order to meet trial deliverables
- Maintain trial metrics
- Ensure trial is conducted in accordance with Moderna and ICH/GCP standards including multiple regions in global trials
- Support testing clinical trial systems/databases (i.e. UAT)
- May support additional clinical trial(s) in an unblinded Clinical Trial Manager capacity
- Develop and maintain strong, collaborative relationships with key stakeholders within Moderna
Here’s What You’ll Bring To The Table
- At least 5 five years of trial coordination experience in a clinical research and industry environment
- Advanced degree preferred or Bachelor’s in a science-based subject
- Relevant experience in global setting
- Solid understanding of drug development
- Good project management skills
- Good understanding of FDA and ICH GCP guidelines to ensure the appropriate conduct of clinical studies
- Excellent verbal and written communication skills
- Good organizational skills and attention to detail
Pay & Benefits
At Moderna, we believe that when you feel your best, you can do your best work.
That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between.
- Competitive healthcare, plus voluntary benefit programs to support your unique needs
- A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
- Family planning benefits, including fertility, adoption, and surrogacy support
- Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
- Savings and investments to help you plan for the future
- Location-specific perks and extras
The salary range for this role is $109,200.00 - $174,600.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs. The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities. We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S. If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Our Working Model
As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact. Moderna is a smoke-free, alcohol-free, and drug-free work environment.
Equal Opportunities
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply! Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Accommodations
We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best. Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at leavesandaccommodations@modernatx.com.
See All 20 Senior Clinical Trial Manager Jobs in Massachusetts
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Where Massachusetts roles are concentrated, by current openings.
Senior Clinical Trial Manager Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Science & Research
- Biotechnology & Pharmaceuticals
What Massachusetts Employers Look For
The qualifications that appear most often in senior clinical trial manager jobs across Massachusetts.
- Bachelor's degree in life sciences, nursing, or a related clinical field required
- Minimum five years of clinical trial management experience with multi-site oversight
- Demonstrated knowledge of ICH E6 Good Clinical Practice guidelines and FDA regulations
- Experience managing CROs, site contracts, and budgets across complex trial portfolios
- Proficiency with electronic data capture systems such as Medidata Rave or Veeva Vault
- Strong cross-functional leadership skills coordinating medical, regulatory, and operational teams
Senior Clinical Trial Manager Jobs in Massachusetts: Frequently Asked Questions
How do you become a senior clinical trial manager in Massachusetts?
Most senior clinical trial managers in Massachusetts hold a bachelor's degree in a life science, nursing, or allied health field, though many employers prefer a master's degree or advanced clinical background. There is no Massachusetts state license specific to clinical trial management, but the clinical research field widely recognizes the Certified Clinical Research Professional credential from the Society of Clinical Research Associates. Massachusetts employers typically promote candidates who have managed Phase II or III multi-site studies and have direct oncology or rare disease experience.
Which companies hire senior clinical trial managers in Massachusetts?
Employers hiring senior clinical trial managers in Massachusetts right now include Biogen, Moderna, and Galderma, based on current listings on Migrate Mate as of August 2026. Massachusetts's dense concentration of biopharma headquarters and academic medical centers means hiring is active year-round, with particularly strong demand from companies running oncology and rare disease pipelines out of the Greater Boston and Cambridge corridors.
Which Massachusetts cities have the most senior clinical trial manager jobs?
The cities with the most senior clinical trial manager openings in Massachusetts are Boston, Cambridge, and Waltham. Boston and Cambridge together anchor the state's biopharma and academic medical center ecosystem, generating the majority of postings, while Worcester draws hiring from UMass Memorial Health and nearby biomanufacturing operations that support active trial portfolios.
Are there remote senior clinical trial manager jobs in Massachusetts?
Yes, and more than most clinical roles, because senior clinical trial managers spend significant time coordinating remotely with sites, CROs, and sponsors rather than conducting hands-on patient procedures. About 91% of senior clinical trial manager openings tied to Massachusetts are remote or hybrid as of August 2026, reflecting how heavily this role relies on documentation, vendor oversight, and cross-functional communication. Protocol development, site monitoring oversight, and regulatory coordination are the functions most commonly performed remotely.
How can I get hired as a senior clinical trial manager in Massachusetts with little or no experience?
The most realistic entry path is starting as a clinical trial coordinator or clinical research associate at a Massachusetts academic medical center or sponsor company, then building toward a manager role through a series of progressively larger studies. Boston-area institutions like Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Massachusetts General Hospital Brigham run structured research coordinator programs that give early-career candidates direct trial exposure. Earning the Certified Clinical Research Associate credential and gaining experience with electronic data capture platforms strengthens a candidate's profile considerably for that first manager promotion.
Where can I find and apply to senior clinical trial manager jobs in Massachusetts?
You can find and apply to senior clinical trial manager jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings updated regularly. Find roles that match your experience and specialization and apply directly to the employers posting them.
See All 20 Senior Clinical Trial Manager Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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