Senior Data Science Engineer Jobs in San Francisco, CA

Senior Data Science Engineer jobs in San Francisco are concentrated in SoMa, the Financial District, and Mission Bay, driven by demand from tech platforms, fintech firms, and life sciences companies. Employers hiring right now include Adobe, Lyft, and GoFundMe. See the openings below and apply to the ones that match your experience.

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Overview

Open roles32
Top employerAdobe
Work type48% Hybrid
Top credentialBachelor's
Companies hiring22

Showing 5 of 32+ Senior Data Science Engineer jobs

MrBeast
Data Science Engineer
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MrBeast
Added 1w ago
Data Science Engineer
MrBeast
San Francisco, California
Data Science & Analytics
Software Engineering
Data Engineering
Data Science
Hybrid
None

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Genentech
Senior Director, Data Science Solutions
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Genentech
Added 2w ago
Senior Director, Data Science Solutions
Genentech
San Francisco, California
Data Science & Analytics
Software Engineering
Strategy & Corporate Development
Project & Program Management
Data Science
AI (Artificial Intelligence)
ML (Machine Learning)
Business Strategy
Project Management
$256k - $475k/yr
Doctoral degree in statistics
10,000+

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Genentech
Senior Director, Data Science Solutions
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Genentech
Added 2w ago
Senior Director, Data Science Solutions
Genentech
San Francisco, California
Data Science & Analytics
Software Engineering
Strategy & Corporate Development
Project & Program Management
Data Science
AI (Artificial Intelligence)
ML (Machine Learning)
Business Strategy
Project Management
$256k - $475k/yr
Doctoral degree in statistics
10,000+

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Amazon Web Services
Delivery Consultant- GenAI/ML & Data Science, Professional Services, AWS Industries
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Amazon Web Services
Added 2w ago
Delivery Consultant- GenAI/ML & Data Science, Professional Services, AWS Industries
Amazon Web Services
San Francisco, California
$154k - $208k/yr
Doctoral degree in Computer Science

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Amazon Web Services
Delivery Consultant- GenAI/ML & Data Science, AWS Industries
We won't show you this job again
Amazon Web Services
Added 2w ago
Delivery Consultant- GenAI/ML & Data Science, AWS Industries
Amazon Web Services
San Francisco, California
$154k - $208k/yr
Certification

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See All 32 Senior Data Science Engineer Jobs in San Francisco

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Senior Data Science Engineer Job Market in San Francisco

Who's Hiring

  • Adobe
    Adobe5
  • Lyft
    Lyft3
  • GoFundMe
    GoFundMe2
  • Genentech
    Genentech2
  • Stitch Fix
    Stitch Fix2

Top Industries Hiring

  • Technology & Software21
  • Retail3
  • Fintech2
  • Medical Devices2
  • Distribution & Wholesale2

Senior Data Science Engineer Jobs in San Francisco: Frequently Asked Questions

How do I get a senior data science engineer job in San Francisco?

Focus your search on SoMa, Mission Bay, and the Financial District, where tech platforms, fintech firms, and biotech companies concentrate their data science teams. Candidates who stand out in San Francisco typically combine production-level ML experience with strong Python or Scala skills and can show measurable business impact. Networking through local data science meetups and contributing to open-source projects visible to Bay Area employers also gives you a concrete edge.

Which companies hire senior data science engineers in San Francisco?

Employers hiring senior data science engineers in San Francisco right now include Adobe, Lyft, and GoFundMe, based on current listings on Migrate Mate as of June 2026. San Francisco's market includes a broad mix of late-stage startups, established tech giants, and financial services firms, all maintaining active data science teams.

Are there remote senior data science engineer jobs in San Francisco?

Yes, senior data science engineer roles are well-suited to remote and hybrid arrangements because the work is primarily analytical and code-based rather than on-site. About 67% of senior data science engineer openings tied to San Francisco are remote or hybrid as of June 2026, reflecting the tech sector's continued flexibility. Modeling, experimentation, and pipeline development are the functions most commonly performed remotely by San Francisco-based teams.

How can I get a senior data science engineer job in San Francisco with little or no experience?

The most realistic entry path in San Francisco is securing a junior data scientist or data analyst role at a mid-size tech company in SoMa or the Financial District and building toward senior-level ownership within two to three years. Early-career candidates gain traction by contributing to well-documented projects on GitHub, completing relevant Kaggle competitions, or landing contract work through San Francisco's active startup ecosystem. Targeting growth-stage startups, which often promote quickly, can accelerate your path to a senior title.

Which industries hire the most senior data science engineers in San Francisco?

Most senior data science engineer openings in San Francisco sit in Technology & Software, Retail, and Fintech, per current listings on Migrate Mate as of June 2026. San Francisco's density of tech platforms, fintech companies, and life sciences organizations drives consistent demand for senior data science talent across these sectors.

See All 32 Senior Data Science Engineer Jobs in San Francisco

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