Senior Data Science Engineer Jobs in San Francisco, CA

Senior Data Science Engineer jobs in San Francisco are concentrated in SoMa, the Financial District, and Mission Bay, driven by demand from tech platforms, fintech firms, and life sciences companies. Employers hiring right now include Lyft, SIA, and Amazon Web Services. See the openings below and apply to the ones that match your experience.

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Overview

Open roles117+
Top employerLyft
Work type54% Hybrid
Top credentialAssociate's
Companies hiring19

Showing 5 of 117+ Senior Data Science Engineer jobs

Amazon Web Services
Senior Data Scientist, AWS Central Econ and Science
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Amazon Web Services
New 11h ago
Senior Data Scientist, AWS Central Econ and Science
Amazon Web Services
San Francisco, California
Business Strategy
Compliance & Risk
Consulting & Professional Services
$175k - $248k/yr

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Meta
Director, Data Science - New Revenue Bets
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Meta
Added 1d ago
Director, Data Science - New Revenue Bets
Meta
San Francisco, California
Business Development
Partnerships & Business Development
Sales
$253k - $314k/yr
Doctoral degree in statistics
10,000+

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OpenAI
Head of Data Science, Strategic Finance
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OpenAI
Added 2d ago
Head of Data Science, Strategic Finance
OpenAI
San Francisco, California
Business Strategy
Consulting & Professional Services
Strategy & Corporate Development
Hybrid
Doctoral degree in statistics
51-200

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Amgen
Data Science Sr Director, Research Data Domain Lead
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Amgen
Added 1w ago
Data Science Sr Director, Research Data Domain Lead
Amgen
San Francisco, California
Business Development
Events & Tourism
Executive Leadership & C-Suite
Project Management
On-Site
Doctoral degree
10,000+

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LexisNexis Legal & Professional
Manager Data Science**Home based San Francisco, CA
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LexisNexis Legal & Professional
Added 1w ago
Manager Data Science**Home based San Francisco, CA
LexisNexis Legal & Professional
San Francisco, California
Customer Service
Customer Support
$115k - $192k/yr
10,000+

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See All 117+ Senior Data Science Engineer Jobs in San Francisco

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Senior Data Science Engineer Job Market in San Francisco

Who's Hiring

  • Lyft
    Lyft15
  • SIA
    SIA10
  • Amazon Web Services
    Amazon Web Services10
  • University of California - San Francisco
    University of California - San Francisco10
  • Meta
    Meta5

Top Industries Hiring

  • Technology & Software20
  • Education5
  • Distribution & Wholesale5
  • Banking & Financial Services5

Senior Data Science Engineer Jobs in San Francisco: Frequently Asked Questions

How do I get a senior data science engineer job in San Francisco?

Focus your search on SoMa, Mission Bay, and the Financial District, where tech platforms, fintech firms, and biotech companies concentrate their data science teams. Candidates who stand out in San Francisco typically combine production-level ML experience with strong Python or Scala skills and can show measurable business impact. Networking through local data science meetups and contributing to open-source projects visible to Bay Area employers also gives you a concrete edge.

Which companies hire senior data science engineers in San Francisco?

Employers hiring senior data science engineers in San Francisco right now include Lyft, SIA, and Amazon Web Services, based on current listings on Migrate Mate as of October 2026. San Francisco's market includes a broad mix of late-stage startups, established tech giants, and financial services firms, all maintaining active data science teams.

Are there remote senior data science engineer jobs in San Francisco?

Yes, senior data science engineer roles are well-suited to remote and hybrid arrangements because the work is primarily analytical and code-based rather than on-site. About 72% of senior data science engineer openings tied to San Francisco are remote or hybrid as of October 2026, reflecting the tech sector's continued flexibility. Modeling, experimentation, and pipeline development are the functions most commonly performed remotely by San Francisco-based teams.

How can I get a senior data science engineer job in San Francisco with little or no experience?

The most realistic entry path in San Francisco is securing a junior data scientist or data analyst role at a mid-size tech company in SoMa or the Financial District and building toward senior-level ownership within two to three years. Early-career candidates gain traction by contributing to well-documented projects on GitHub, completing relevant Kaggle competitions, or landing contract work through San Francisco's active startup ecosystem. Targeting growth-stage startups, which often promote quickly, can accelerate your path to a senior title.

Which industries hire the most senior data science engineers in San Francisco?

Most senior data science engineer openings in San Francisco sit in Technology & Software, Education, and Distribution & Wholesale, per current listings on Migrate Mate as of October 2026. San Francisco's density of tech platforms, fintech companies, and life sciences organizations drives consistent demand for senior data science talent across these sectors.

See All 117+ Senior Data Science Engineer Jobs in San Francisco

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