Senior Data Science Engineer Jobs in Chicago, IL

Senior Data Science Engineer jobs in Chicago are concentrated in the Loop, River North, and the Fulton Market tech corridor, with strong demand across fintech, healthcare analytics, and enterprise software. Employers hiring right now include University of Chicago, University of Illinois, and CCC Intelligent Solutions. Find a role that fits below and apply directly.

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Overview

Open roles21
Top employerUniversity of Chicago
Work type67% Hybrid
Top credentialMaster's
Companies hiring13

Showing 5 of 21+ Senior Data Science Engineer jobs

CCC Intelligent Solutions
Data Science Engineer Internship
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CCC Intelligent Solutions
Added 2d ago
Data Science Engineer Internship
CCC Intelligent Solutions
Chicago, Illinois
Customer Support
IT Support
Technical Program Management
$20 - $43/hr
1,001-5,000

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University of Illinois
Faculty Open Rank (Tenure) - Data Science and AI in Health Professions Education – Medical Education
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University of Illinois
Added 2d ago
Faculty Open Rank (Tenure) - Data Science and AI in Health Professions Education – Medical Education
University of Illinois
Chicago, Illinois
Data Science
Data Science & Analytics
ML (Machine Learning)
$90k - $250k/yr
10,000+

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University of Illinois
Faculty Open Rank (Non Tenure) Data Science and AI in Health Professions Education
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University of Illinois
Added 2d ago
Faculty Open Rank (Non Tenure) Data Science and AI in Health Professions Education
University of Illinois
Chicago, Illinois
Data Science
Data Science & Analytics
ML (Machine Learning)
$90k - $250k/yr
10,000+

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CCC Intelligent Solutions
R&D & Data Science Internship Fall 2026
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CCC Intelligent Solutions
Added 3d ago
R&D & Data Science Internship Fall 2026
CCC Intelligent Solutions
Chicago, Illinois
Account Management
Customer Service
Customer Success
$20 - $43/hr
1,001-5,000

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MonoSol LLC.
Senior Scientist Data Science
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MonoSol LLC.
Added 4d ago
Senior Scientist Data Science
MonoSol LLC.
Chicago, Illinois
Communications
Content & Communications
Public Relations (PR)
$130k - $155k/yr
Hybrid
Bachelor's degree in statistics
201-500

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See All 21 Senior Data Science Engineer Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

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Senior Data Science Engineer Job Market in Chicago

Who's Hiring

University of Chicago
University of Chicago3 open roles
University of Illinois
University of Illinois3 open roles
CCC Intelligent Solutions
CCC Intelligent Solutions3 open roles

Top Industries Hiring

  • Education
  • Banking & Financial Services
  • Consulting & Professional Services
  • Media & Entertainment

Senior Data Science Engineer Jobs in Chicago: Frequently Asked Questions

How do I get a senior data science engineer job in Chicago?

Focus your search on Chicago's fintech corridor, the health systems clustered along the Medical District, and the enterprise tech firms headquartered in the Loop and Fulton Market. Candidates who combine strong ML engineering skills with domain knowledge in finance or healthcare move fastest here. Building a portfolio that demonstrates production-scale model deployment, not just research work, gives you a concrete edge with Chicago employers.

Which companies hire senior data science engineers in Chicago?

Employers hiring senior data science engineers in Chicago right now include University of Chicago, University of Illinois, and CCC Intelligent Solutions, based on current listings on Migrate Mate as of August 2026. Chicago's hiring mix tends to favor established financial services firms, major health systems, and mid-to-large enterprise tech companies rather than early-stage startups.

Are there remote senior data science engineer jobs in Chicago?

Yes, senior data science engineer work is well-suited to remote and hybrid arrangements because the core work is analytical and code-driven rather than on-site. About 75% of senior data science engineer openings tied to Chicago are remote or hybrid as of August 2026, reflecting broad adoption across the sector. Model development, pipeline work, and stakeholder reporting are the functions most commonly performed fully remote in Chicago-based roles.

How can I get a senior data science engineer job in Chicago with little or no experience?

The most realistic entry path in Chicago is through associate or junior data scientist roles at the city's large financial institutions and health systems, which run structured analyst programs that feed into senior tracks. Targeting companies in the Fulton Market tech cluster for data engineering apprenticeships or contract-to-hire roles is another practical route. Strong Python skills, a GitHub portfolio with real pipelines, and familiarity with cloud platforms move entry-level candidates to the top of local shortlists.

Which industries hire the most senior data science engineers in Chicago?

The sectors hiring the most senior data science engineers in Chicago are Education, Banking & Financial Services, and Consulting & Professional Services, based on current listings on Migrate Mate as of August 2026. Chicago's position as a national hub for commodity trading, insurance, and healthcare systems creates sustained, year-round demand for senior-level data science engineering across those fields.

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