Senior Data Science Engineer Jobs in Chicago, IL

Senior Data Science Engineer jobs in Chicago are concentrated in the Loop, River North, and the Fulton Market tech corridor, with strong demand across fintech, healthcare analytics, and enterprise software. Employers hiring right now include University of Illinois, Federal Reserve Bank of Chicago, and Mars. Find a role that fits below and apply directly.

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Overview

Open roles27
Top employerUniversity of Illinois
Work type85% Hybrid
Top credentialBachelor's degree in statistics
Companies hiring9

Showing 5 of 27+ Senior Data Science Engineer jobs

Federal Reserve Bank of Chicago
Summer 2027 Intern- PhD Data Science or Computer Science
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Federal Reserve Bank of Chicago
Added 1d ago
Summer 2027 Intern- PhD Data Science or Computer Science
Federal Reserve Bank of Chicago
Chicago, Illinois
Business Analysis
Data Analytics
Data Science
$20 - $33/hr
1,001-5,000

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Federal Reserve Bank of Chicago
Summer 2027 Intern-Data Science and Business Analytics
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Federal Reserve Bank of Chicago
Added 1d ago
Summer 2027 Intern-Data Science and Business Analytics
Federal Reserve Bank of Chicago
Chicago, Illinois
Data Analytics
Data Science
$20 - $33/hr
1,001-5,000

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Mars
Sr Data Science Analyst
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Mars
Added 4d ago
Sr Data Science Analyst
Mars
Chicago, Illinois
Business Analysis
Data Analytics
Data Science
$75k - $102k/yr
Bachelor's degree in statistics
10,000+

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University of Illinois
Director of Informatics and Data Science Operations and Development
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University of Illinois
Added 1w ago
Director of Informatics and Data Science Operations and Development
University of Illinois
Chicago, Illinois
Program Management
Project & Program Management
Project Management
$125k - $175k/yr
Master's degree
10,000+

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Oasis Health Partners
Director of Data Science
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Oasis Health Partners
Added 2w ago
Director of Data Science
Oasis Health Partners
Chicago, Illinois
Business Analysis
Data Analytics
Data Science
Remote (US)
Managed care organization experience

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See All 27 Senior Data Science Engineer Jobs in Chicago

Find roles in Chicago that match your experience and apply in just a few clicks.

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Senior Data Science Engineer Job Market in Chicago

Who's Hiring

University of Illinois
University of Illinois7 open roles
Federal Reserve Bank of Chicago
Federal Reserve Bank of Chicago5 open roles
Mars
Mars2 open roles

Top Industries Hiring

  • Education
  • Media & Entertainment
  • Banking & Financial Services

Senior Data Science Engineer Jobs in Chicago: Frequently Asked Questions

How do I get a senior data science engineer job in Chicago?

Focus your search on Chicago's fintech corridor, the health systems clustered along the Medical District, and the enterprise tech firms headquartered in the Loop and Fulton Market. Candidates who combine strong ML engineering skills with domain knowledge in finance or healthcare move fastest here. Building a portfolio that demonstrates production-scale model deployment, not just research work, gives you a concrete edge with Chicago employers.

Which companies hire senior data science engineers in Chicago?

Employers hiring senior data science engineers in Chicago right now include University of Illinois, Federal Reserve Bank of Chicago, and Mars, based on current listings on Migrate Mate as of October 2026. Chicago's hiring mix tends to favor established financial services firms, major health systems, and mid-to-large enterprise tech companies rather than early-stage startups.

Are there remote senior data science engineer jobs in Chicago?

Yes, senior data science engineer work is well-suited to remote and hybrid arrangements because the core work is analytical and code-driven rather than on-site. About 100% of senior data science engineer openings tied to Chicago are remote or hybrid as of October 2026, reflecting broad adoption across the sector. Model development, pipeline work, and stakeholder reporting are the functions most commonly performed fully remote in Chicago-based roles.

How can I get a senior data science engineer job in Chicago with little or no experience?

The most realistic entry path in Chicago is through associate or junior data scientist roles at the city's large financial institutions and health systems, which run structured analyst programs that feed into senior tracks. Targeting companies in the Fulton Market tech cluster for data engineering apprenticeships or contract-to-hire roles is another practical route. Strong Python skills, a GitHub portfolio with real pipelines, and familiarity with cloud platforms move entry-level candidates to the top of local shortlists.

Which industries hire the most senior data science engineers in Chicago?

The sectors hiring the most senior data science engineers in Chicago are Education, Media & Entertainment, and Banking & Financial Services, based on current listings on Migrate Mate as of October 2026. Chicago's position as a national hub for commodity trading, insurance, and healthcare systems creates sustained, year-round demand for senior-level data science engineering across those fields.

See All 27 Senior Data Science Engineer Jobs in Chicago

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