Senior Fullstack Software Engineer Jobs in San Francisco, CA
Senior Fullstack Software Engineer jobs in San Francisco are concentrated in SoMa, the Financial District, and Mission Bay, with strong demand from OpenAI, Rippling, and Anthropic in fintech, enterprise software, and healthtech. Senior engineers who can own product delivery end-to-end across React, Node, and cloud infrastructure are in particularly high demand here. Find a role that fits below and apply directly.
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Senior Software Engineer (Full-Stack)
Employment Type: Full-time
Work Type: Hybrid
Location: San Francisco
Company: Roger Healthcare
About This Role
We are looking for a Senior Software Engineer with 5+ years of experience to join our small, lean team of ten engineers. We are seeking a candidate with a strong backend focus, startup experience (Pre-seed to Series B), and a passion for healthcare. This individual will be a core team member, taking on significant ownership to help scale our core services and build new Generative AI and LLM-driven workflows.
What Will You Be Doing?
- Build and ship complex backend services and infrastructure that interface with LLMs and Generative AI models.
- Take ownership of zero-to-one projects, from prototyping MVPs to hardening them into scalable, secure, and reliable production systems.
- Help scale our existing, widely adopted products as we launch to more organizations.
- Improve backend architecture, observability, and code quality standards.
- Collaborate within a flat engineering structure, working directly with other engineers and the CTO.
Pay: $144,301.88 - $173,782.91 per year
Work Location: Hybrid remote in San Francisco, CA 94114
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Find JobsSenior Fullstack Software Engineer Job Market in San Francisco
Who's Hiring
- OpenAI47
- Rippling33
- Anthropic8
- Atlassian8
- Salesforce8
Top Industries Hiring
- Technology & Software56
- Science & Research22
- Agriculture & Farming3
- Banking & Financial Services3
- Healthcare & Medical Services3
Senior Fullstack Software Engineer Jobs in San Francisco: Frequently Asked Questions
How do I get a senior fullstack software engineer job in San Francisco?
The clearest path is targeting San Francisco's dense fintech, enterprise SaaS, and healthtech corridors, particularly employers based in SoMa, Mission Bay, and the Financial District. Companies here prioritize engineers who can lead architecture decisions and ship across the full stack independently. A portfolio demonstrating ownership of production systems, experience with modern cloud infrastructure, and contributions to cross-functional teams gives candidates a real edge over those with narrower specializations.
Which companies hire senior fullstack software engineers in San Francisco?
San Francisco senior fullstack software engineer roles are posted by OpenAI, Rippling, and Anthropic and others right now, based on current listings on Migrate Mate as of September 2026. San Francisco's hiring base skews heavily toward venture-backed startups, late-stage growth companies, and established technology firms that maintain their core engineering presence in the city.
Are there remote senior fullstack software engineer jobs in San Francisco?
Yes, senior fullstack software engineering is one of the more remote-compatible roles in tech, since the work centers on code and collaboration tools rather than physical presence. About 62% of senior fullstack software engineer openings tied to San Francisco are remote or hybrid as of September 2026, reflecting how many Bay Area employers have normalized distributed engineering teams. Architecture reviews, product syncs, and on-call rotations are the functions most likely to require occasional in-person days.
How can I get a senior fullstack software engineer job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is landing a junior or mid-level fullstack role at a smaller SoMa or Mission District startup willing to invest in growth, then building toward senior scope through ownership of a product surface or service. San Francisco bootcamp graduates and early-career engineers often break in through associate engineering programs at growth-stage companies, contract-to-hire arrangements, or referrals from the city's active developer meetup and hackathon scene.
Which industries hire the most senior fullstack software engineers in San Francisco?
Most senior fullstack software engineer openings in San Francisco sit in Technology & Software, Science & Research, and Agriculture & Farming, per current listings on Migrate Mate as of September 2026. San Francisco's role as a global hub for venture capital and technology company formation means these sectors sustain consistently high engineering headcount even when national hiring cools.
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