Senior ML Engineer Jobs in San Francisco, CA

Senior ML Engineer jobs in San Francisco are in high demand, concentrated in SoMa, Mission Bay, and the Financial District across AI infrastructure, enterprise software, and biotech. Employers hiring right now include DoorDash, Lila Sciences, and Pinterest. See the openings below and apply to the ones that match your experience.

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Overview

Open roles896+
Top employerDoorDash
Work type46% Hybrid
Companies hiring86

Showing 5 of 896+ Senior ML Engineer jobs

Uber
Software Engineer II - Machine Learning Engineer
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Uber
Added 1d ago
Software Engineer II - Machine Learning Engineer
Uber
San Francisco, California
AI (Artificial Intelligence)
Data Science
$171k - $190k/yr
10,000+

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Uber
Sr Machine Learning Engineer
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Uber
Added 1d ago
Sr Machine Learning Engineer
Uber
San Francisco, California
Data Science
Data Science & Analytics
ML (Machine Learning)
$202k - $224k/yr
Bachelor's degree in statistics
10,000+

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Okta
Principal Machine Learning Engineer, SecureAI
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Okta
Added 1d ago
Principal Machine Learning Engineer, SecureAI
Okta
San Francisco, California
Cloud Engineering
DevOps
Solutions Engineering & Architecture
$238k - $326k/yr
Master's degree
5,001-10,000

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Braze
Staff Machine Learning Engineer, ML Platform
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Braze
Added 1d ago
Staff Machine Learning Engineer, ML Platform
Braze
San Francisco, California
Customer Support
IT Support
IT Support & Systems Administration
Technical Program Management
$184k - $314k/yr
1,001-5,000

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Goliath Partners
Machine Learning Engineer
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Goliath Partners
Added 1d ago
Machine Learning Engineer
Goliath Partners
San Francisco, California
Cloud & DevOps
Cloud Engineering
DevOps
Solutions Engineering & Architecture

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See All 896+ Senior ML Engineer Jobs in San Francisco

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Senior ML Engineer Job Market in San Francisco

Who's Hiring

  • DoorDash
    DoorDash62
  • Lila Sciences
    Lila Sciences56
  • Pinterest
    Pinterest45
  • Uber
    Uber39
  • Genentech
    Genentech34

Top Industries Hiring

  • Technology & Software230
  • Science & Research39
  • Biotechnology & Pharmaceuticals39
  • Artificial Intelligence28
  • Electronics & Hardware22

Senior ML Engineer Jobs in San Francisco: Frequently Asked Questions

How do I get a senior ml engineer job in San Francisco?

San Francisco's senior ML engineer market centers on AI-native startups in SoMa, large tech platforms headquartered in the city, and biotech firms in Mission Bay. Candidates who stand out have production-level experience with large-scale model deployment, a public portfolio of applied ML work, and fluency with the MLOps tooling those sectors use. Networking through local ML meetups and research seminars also gives you a concrete edge over remote applicants.

Which companies hire senior ml engineers in San Francisco?

Employers hiring senior ml engineers in San Francisco right now include DoorDash, Lila Sciences, and Pinterest, based on current listings on Migrate Mate as of September 2026. The local market mixes AI-focused startups, established enterprise software companies, and research-driven biotech firms, all of which maintain dedicated ML engineering teams in the city.

Are there remote senior ml engineer jobs in San Francisco?

Yes, though availability depends on the role. Senior ML engineers working on model research, data pipelines, and evaluation frameworks tend to work remotely more often than those supporting on-premise infrastructure or hardware-adjacent teams. About 63% of senior ml engineer openings tied to San Francisco are remote or hybrid as of September 2026, with the highest share coming from enterprise software and AI platform companies headquartered here.

How can I get a senior ml engineer job in San Francisco with little or no experience?

The most realistic entry path in San Francisco is moving into a junior ML engineer or ML platform engineer role at one of the city's many mid-stage AI startups, which tend to have faster promotion tracks than large tech companies. Contributing to open-source ML projects, completing applied capstone work through local university programs such as UC Berkeley or UCSF data science initiatives, and attending Bay Area ML research events all help you build the portfolio and local connections that San Francisco employers expect before considering a promotion to the senior level.

Which industries hire the most senior ml engineers in San Francisco?

San Francisco senior ml engineer roles concentrate in Technology & Software, Science & Research, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of September 2026. San Francisco's density of AI-native companies, enterprise cloud platforms, and research-oriented biotech firms creates sustained demand for ML talent well beyond what most other U.S. cities generate.

See All 896+ Senior ML Engineer Jobs in San Francisco

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