Senior ML Engineer Jobs in San Francisco, CA
Senior ML Engineer jobs in San Francisco are in high demand, concentrated in SoMa, Mission Bay, and the Financial District across AI infrastructure, enterprise software, and biotech. Employers hiring right now include DoorDash, Lila Sciences, and Pinterest. See the openings below and apply to the ones that match your experience.
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Operating across key business areas like grocery and food, the Consumer Incentives team drives Uber's growth and long-term profitability. We deliver products that create seamless, affordable, and enjoyable customer experiences by building AI/ML-powered intelligence and sophisticated distributed systems at scale for hundreds of millions of global users.
What you'll do
In this role, you will build products powered by advanced AI/ML solutions and scalable distributed systems. Your work will optimize user experiences across multiple verticals, such as grocery and food, while fostering sustainable business growth. Key responsibilities include:
- Launching products to power key consumer experience and business outcomes.
- Driving projects across full lifecycles spanning initial scoping, offline evaluation, experimental testing, production deployment, and post-launch maintenance.
- Designing, tuning, and enhancing systems and algorithms to operate at scale.
- Partnering with cross-functional stakeholders across product management, operations, and data science.
- 3+ years of experience in an AI/ML/optimization role, or a PhD in a relevant field (CS, OR, EE, Statistics, etc.)
- Proficiency in at least one programming language such as Python, Go, or Java
- Strong communication skills and ability to work effectively with cross-functional partners
- Strong sense of ownership to drive projects end-to-end
- Experience in designing and delivering large-scale consumer products
- Experience in developing, evaluating, and deploying ML models & algorithms in production Experience in experimental design and causal inference
For New York City, NY-based roles: The base salary range for this role is USD $171,000 per year - USD $190,000 per year.
For San Francisco, CA-based roles: The base salary range for this role is USD $171,000 per year - USD $190,000 per year.
For Seattle, WA-based roles: The base salary range for this role is USD $171,000 per year - USD $190,000 per year.
For all US locations, you will be eligible to participate in Uber's bonus program, and may be offered an equity award & other types of comp. All full-time employees are eligible to participate in a 401(k) plan. You will also be eligible for various benefits.
Ready to Ride?
This isn't the kind of place where you follow a playbook - it's where you help write one. If you're driven by impact, energized by challenge, and ready to shape how the world moves - we'd love to hear from you.
You may be eligible for bonuses, equity, and other compensation, as well as a range of benefits. Explore our benefits.
Offices remain key to collaboration and Uber's culture. Unless approved for full remote work, employees must spend at least 50% of their time in-office. Some roles, like those at greenlight hubs, require full-time in-office presence. Ask your Recruiter for details about this role's requirements.
Uber is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. If you have a disability or special need that requires accommodation, please let us know by completing this form.
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Find Senior ML Engineer JobsSenior ML Engineer Job Market in San Francisco
Who's Hiring
- DoorDash62

- Lila Sciences56

- Pinterest45

- Uber39

- Genentech34

Top Industries Hiring
- Technology & Software230
- Science & Research39
- Biotechnology & Pharmaceuticals39
- Artificial Intelligence28
- Electronics & Hardware22
Senior ML Engineer Jobs in San Francisco: Frequently Asked Questions
How do I get a senior ml engineer job in San Francisco?
San Francisco's senior ML engineer market centers on AI-native startups in SoMa, large tech platforms headquartered in the city, and biotech firms in Mission Bay. Candidates who stand out have production-level experience with large-scale model deployment, a public portfolio of applied ML work, and fluency with the MLOps tooling those sectors use. Networking through local ML meetups and research seminars also gives you a concrete edge over remote applicants.
Which companies hire senior ml engineers in San Francisco?
Employers hiring senior ml engineers in San Francisco right now include DoorDash, Lila Sciences, and Pinterest, based on current listings on Migrate Mate as of September 2026. The local market mixes AI-focused startups, established enterprise software companies, and research-driven biotech firms, all of which maintain dedicated ML engineering teams in the city.
Are there remote senior ml engineer jobs in San Francisco?
Yes, though availability depends on the role. Senior ML engineers working on model research, data pipelines, and evaluation frameworks tend to work remotely more often than those supporting on-premise infrastructure or hardware-adjacent teams. About 63% of senior ml engineer openings tied to San Francisco are remote or hybrid as of September 2026, with the highest share coming from enterprise software and AI platform companies headquartered here.
How can I get a senior ml engineer job in San Francisco with little or no experience?
The most realistic entry path in San Francisco is moving into a junior ML engineer or ML platform engineer role at one of the city's many mid-stage AI startups, which tend to have faster promotion tracks than large tech companies. Contributing to open-source ML projects, completing applied capstone work through local university programs such as UC Berkeley or UCSF data science initiatives, and attending Bay Area ML research events all help you build the portfolio and local connections that San Francisco employers expect before considering a promotion to the senior level.
Which industries hire the most senior ml engineers in San Francisco?
San Francisco senior ml engineer roles concentrate in Technology & Software, Science & Research, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of September 2026. San Francisco's density of AI-native companies, enterprise cloud platforms, and research-oriented biotech firms creates sustained demand for ML talent well beyond what most other U.S. cities generate.
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