Senior ML Engineer Jobs in Santa Clara, CA

Senior ML Engineer jobs in Santa Clara are in high demand, concentrated in the Central Expressway corridor, the Great America Parkway district, and the broader Silicon Valley tech core, across semiconductor AI, enterprise software, and cloud infrastructure. Employers actively hiring include ServiceNow, PlusAI, and NVIDIA. Find a role that fits below and apply directly.

Find Senior ML Engineer Jobs

Overview

Open roles758+
Top employerServiceNow
Work type60% Hybrid
Top credentialMaster's degree
Companies hiring16

Showing 5 of 758+ Senior ML Engineer jobs

Staff / Sr. ML Engineer, Indexing Infrastructure
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Added 1d ago
Staff / Sr. ML Engineer, Indexing Infrastructure
Apple
Santa Clara, California
Data Engineering
Data Science
ML (Machine Learning)
Software Engineering
$216k - $325k/yr
Doctoral degree in Computer Science
10,000+

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Sr. Principal Machine Learning Software Engineer – Inference Serving Engine
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Added 3d ago
Sr. Principal Machine Learning Software Engineer – Inference Serving Engine
Ampere Computing
Santa Clara, California
Cloud Architecture
Solutions Engineering & Architecture
Technical Product & Program Management
$226k - $356k/yr
Hybrid
Bachelor's degree in electrical engineering
1,001-5,000

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ML Ops DSX Senior Engineer
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Added 4d ago
ML Ops DSX Senior Engineer
NVIDIA
Santa Clara, California
Cloud Engineering
Data Engineering
Software Engineering
$184k - $357k/yr
Remote (US)
Bachelor's degree in electrical engineering
10,000+

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Machine learning engineer II, AWS Inference Optimization
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Added 1w ago
Machine learning engineer II, AWS Inference Optimization
Amazon Web Services
Santa Clara, California
Biotech & Life Sciences
Clinical Trials & Medical Research
Research & Academia
$165k - $224k/yr
Bachelor's degree in engineering

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Senior Software Engineer, GPU Code Generation for Machine Learning Inference
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Added 1w ago
Senior Software Engineer, GPU Code Generation for Machine Learning Inference
NVIDIA
Santa Clara, California
AI (Artificial Intelligence)
Data Science
ML (Machine Learning)
$152k - $288k/yr
Hybrid
Bachelor of Science
10,000+

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See All 758+ Senior ML Engineer Jobs in Santa Clara

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Senior ML Engineer Job Market in Santa Clara

Who's Hiring

  • ServiceNow194
  • PlusAI117
  • NVIDIA97
  • AMD39
  • Apple39

Top Industries Hiring

  • Technology & Software117
  • Artificial Intelligence58
  • Automotive39
  • Transportation & Logistics39
  • Manufacturing19

Senior ML Engineer Jobs in Santa Clara: Frequently Asked Questions

How do I get a senior ml engineer job in Santa Clara?

Focus on Santa Clara's dominant hiring sectors: semiconductor and chip design companies along the Central Expressway corridor, enterprise software firms near Great America Parkway, and cloud infrastructure teams embedded in the broader Silicon Valley ecosystem. Candidates who can demonstrate production ML deployment experience, familiarity with large-scale data pipelines, and hands-on work with hardware-adjacent model optimization stand out in this market. Targeting mid-size AI-first companies alongside established tech employers broadens your options considerably.

Which companies hire senior ml engineers in Santa Clara?

Santa Clara senior ml engineer roles are posted by ServiceNow, PlusAI, and NVIDIA and others right now, based on current listings on Migrate Mate as of November 2026. Santa Clara's employer base skews heavily toward semiconductor giants, enterprise cloud platforms, and hardware-software integrated tech companies that build AI capabilities directly into their core products.

Are there remote senior ml engineer jobs in Santa Clara?

Yes, though senior ml engineer roles that involve hardware integration, lab environments, or on-site infrastructure tend to require in-person presence. About 75% of senior ml engineer openings tied to Santa Clara are remote or hybrid as of November 2026, reflecting how distributed many software-layer ML teams have become. Model training, research, and MLOps work are the functions most commonly offered with remote or hybrid flexibility in this market.

How can I get a senior ml engineer job in Santa Clara with little or no experience?

The most realistic entry path is targeting associate or junior ML engineer roles at Santa Clara's mid-size AI software companies and semiconductor firms, which often promote from within as projects scale. Contributing to open-source ML projects, building a portfolio of production-ready models, and pursuing internships with companies operating in the Great America Parkway and Central Expressway corridors builds the local credibility that hiring managers here respond to. Data engineer and ML infrastructure roles also serve as strong lateral moves into senior ML tracks.

Which industries hire the most senior ml engineers in Santa Clara?

The sectors hiring the most senior ml engineers in Santa Clara are Technology & Software, Artificial Intelligence, and Automotive, based on current listings on Migrate Mate as of November 2026. Santa Clara's position as a global hub for semiconductor design and enterprise cloud infrastructure means AI and ML talent is absorbed primarily by companies building the underlying technology layers rather than consumer-facing applications.

See All 758+ Senior ML Engineer Jobs in Santa Clara

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