Senior ML Engineer Jobs in Massachusetts

Senior ML Engineer jobs in Massachusetts are among the most actively recruited roles in the region, concentrated in biotech, financial services, robotics, and enterprise software across a market that ranges from early-career machine learning engineers through principal-level researchers. Boston and Cambridge drive the bulk of hiring, anchored by companies like Google, Amazon, and Biogen, with a secondary cluster in Waltham and Burlington along Route 128. The most in-demand specialties are large language model fine-tuning, computer vision for life sciences applications, and MLOps infrastructure. Find a role that fits below and apply directly.

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Overview

Open roles94
Top employerWhoop
Top cityBoston, MA
Cities hiring14
Work type56% On-site
Top industryTechnology

Showing 5 of 94+ Senior ML Engineer jobs

AIML - Machine Learning Engineer, Evaluation - Responsible AI and Safety
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AIML - Machine Learning Engineer, Evaluation - Responsible AI and Safety
Apple
Cambridge, Massachusetts
Backend Engineering
Full-stack Engineering
Software Engineering
$166k - $292k/yr
10,000+

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Senior Machine Learning Engineer - Active Learning
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Senior Machine Learning Engineer - Active Learning
Sense
Cambridge, Massachusetts
Data Science
Data Science & Analytics
ML (Machine Learning)
$165k - $185k/yr
Remote (US)
Master's degree in physics

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Director, Software Engineering- Machine Learning (Individual Contributor)
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Director, Software Engineering- Machine Learning (Individual Contributor)
Fidelity Investments
Boston, Massachusetts
Business Development
Events & Tourism
Executive Leadership & C-Suite
Project Management
$126k - $255k/yr
Remote (US)
10,000+

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Protein ML Senior Principal Data Scientist
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Protein ML Senior Principal Data Scientist
Sanofi
Waltham, Massachusetts
AI (Artificial Intelligence)
Data Science
Data Science & Analytics
ML (Machine Learning)
$149k - $215k/yr
10,000+

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Senior Machine Learning Engineer
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Added 6d ago
Senior Machine Learning Engineer
Symbotic
Wilmington, Massachusetts
Business Analysis
Data Analytics
Data Science
$116k - $171k/yr
Hybrid
Bachelor's degree
501-1,000

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See All 94 Senior ML Engineer Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

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Senior ML Engineer Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Cambridge
19 jobs
Waltham
7 jobs
Wilmington
4 jobs
Bedford
3 jobs
Salem
2 jobs
Milford
2 jobs
Lexington
2 jobs
Watertown
2 jobs

Senior ML Engineer Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

Whoop6 open roles
Wayfair5 open roles
Lila Sciences5 open roles

Top Industries Hiring

  • Technology & Software
  • Biotechnology & Pharmaceuticals
  • Automotive
  • Medical Devices
  • Artificial Intelligence

What Massachusetts Employers Look For

The qualifications that appear most often in senior ML engineer jobs across Massachusetts.

  • Master's or PhD in computer science, statistics, or a related quantitative field
  • Five or more years of experience building and deploying machine learning models in production
  • Proficiency in Python and core ML frameworks such as PyTorch or TensorFlow
  • Experience with cloud ML platforms including AWS SageMaker, Azure ML, or Google Vertex AI
  • Demonstrated ability to lead model design reviews and mentor junior engineers on the team
  • Familiarity with MLOps tooling such as MLflow, Kubeflow, or similar pipeline orchestration systems

Senior ML Engineer Jobs in Massachusetts: Frequently Asked Questions

How do you become a senior ml engineer in Massachusetts?

Senior ml engineer roles in Massachusetts do not require a state-issued license or registration. The typical path starts with a bachelor's or master's degree in computer science, applied mathematics, or a related field, followed by several years building production ML systems. Massachusetts employers, particularly those in biotech and fintech, place strong weight on demonstrated project ownership, published research, or a public portfolio of deployed models when evaluating candidates for senior-level positions.

How much do senior ML engineers make in Massachusetts?

Senior ML engineers in Massachusetts earn a median of about $109,590 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $55,740 for the lowest 10% to over $183,460 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire senior ml engineers in Massachusetts?

Employers hiring senior ml engineers in Massachusetts right now include Whoop, Wayfair, and Lila Sciences, based on current listings on Migrate Mate as of November 2026. Massachusetts's concentration of biotech firms, financial technology companies, and robotics startups along the Route 128 corridor means hiring tends to be broad across industries rather than limited to a single sector.

Which Massachusetts cities have the most senior ml engineer jobs?

The cities with the most senior ml engineer openings in Massachusetts are Boston, Cambridge, and Waltham. Boston and Cambridge dominate because of their dense cluster of research hospitals, university spinouts, and major tech offices, while suburban hubs like Waltham and Burlington attract large employers who established campuses along the Route 128 technology corridor decades ago.

Are there remote senior ml engineer jobs in Massachusetts?

Yes, and more than most fields. About 44% of senior ml engineer openings tied to Massachusetts are remote or hybrid as of November 2026, reflecting how much of the work involves code, data pipelines, and model experiments that travel well over a laptop. Model design reviews and stakeholder presentations are the parts most likely to require occasional in-person presence for Massachusetts-based roles.

How can I get hired as a senior ml engineer in Massachusetts with little or no experience?

The most realistic entry path is through a machine learning engineer or data scientist role at a Massachusetts employer, then building toward seniority. Companies like Biogen, Liberty Mutual, and MathWorks hire associate or mid-level ML engineers and promote from within. New graduates can strengthen their candidacy with a strong GitHub portfolio, contributions to open-source ML projects, or a research publication from a Massachusetts university lab. Lateral moves from data engineering or quantitative analysis roles are common and well-recognized by Boston-area hiring teams.

Where can I find and apply to senior ml engineer jobs in Massachusetts?

You can find and apply to senior ml engineer jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across industries. Find the roles that fit your background and apply directly from the listings on this page.

See All 94 Senior ML Engineer Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

Find Senior ML Engineer Jobs