Senior ML Engineer Jobs in Boston, MA

Senior ML Engineer jobs in Boston are in strong demand, with openings concentrated in the Seaport, Kendall Square, and the Longwood Medical Area across biotech, financial services, and enterprise software. Employers actively hiring include Wayfair, Whoop, and Zoox. Scan the live roles below and apply to whichever ones fit.

Find Senior ML Engineer Jobs

Overview

Open roles74
Top employerWayfair
Work type73% On-site
Top credentialMaster's
Companies hiring23

Showing 5 of 74+ Senior ML Engineer jobs

PathAI
Senior Software Engineer, ML Ops
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PathAI
Added 6d ago
Senior Software Engineer, ML Ops
PathAI
Boston, Massachusetts
Backend Engineering
Full-stack Engineering
Software Engineering
$128k - $196k/yr
Hybrid
Bachelor of Science

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P
Machine Learning Engineer
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P
Added 1w ago
Machine Learning Engineer
Powertown
Boston, Massachusetts
Backend Engineering
Full-stack Engineering
Software Engineering
$190k - $200k/yr

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P
Machine Learning Engineer, Intern
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P
Added 1w ago
Machine Learning Engineer, Intern
Powertown
Boston, Massachusetts
Backend Engineering
Full-stack Engineering
Software Engineering
$190k - $200k/yr

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CVS Health
Senior Technical Product Manager – AI / ML
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CVS Health
Added 2w ago
Senior Technical Product Manager – AI / ML
CVS Health
Boston, Massachusetts
AI (Artificial Intelligence)
Data Science
$107k - $284k/yr
Bachelor's degree in Physics
10,000+

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Wayfair
Machine Learning Scientist III, Ads Optimization & Automation
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Wayfair
Added 2w ago
Machine Learning Scientist III, Ads Optimization & Automation
Wayfair
Boston, Massachusetts
Business Operations
Project Management
$185k - $196k/yr
Bachelor of Science
10,000+

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See All 74 Senior ML Engineer Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find Senior ML Engineer Jobs

Senior ML Engineer Job Market in Boston

Who's Hiring

  • Wayfair
    Wayfair10
  • Whoop
    Whoop8
  • Zoox
    Zoox6
  • STR
    STR4
  • Chewy
    Chewy4

Top Industries Hiring

  • Technology & Software14
  • Investment & Asset Management8
  • Automotive6
  • E-Commerce & Online Marketplaces6
  • Insurance4

Senior ML Engineer Jobs in Boston: Frequently Asked Questions

How do I get a senior ml engineer job in Boston?

Focus your search on Boston's core hiring clusters: biotech and life sciences firms in the Longwood Medical Area and Cambridge, financial technology companies in the Seaport, and enterprise software companies across the Back Bay and downtown. Candidates who demonstrate production-scale model deployment, strong Python skills, and domain fluency in life sciences or finance move fastest here. Applying directly to mid-size growth companies, not just big tech, widens your options considerably.

Which companies hire senior ml engineers in Boston?

Companies currently hiring senior ml engineers in Boston include Wayfair, Whoop, and Zoox, per current listings on Migrate Mate as of September 2026. Boston's hiring base skews toward research-driven biotech firms, quantitative finance shops, and well-funded software scale-ups rather than a single dominant tech employer.

Are there remote senior ml engineer jobs in Boston?

Yes, though it depends on the role: senior ml engineer positions that emphasize model research and data pipeline work tend to offer more remote flexibility than those requiring on-site lab access or hardware integration. About 27% of senior ml engineer openings tied to Boston are remote or hybrid as of September 2026. Research-focused roles at Boston biotech and software firms are the most likely to support fully remote arrangements.

How can I get a senior ml engineer job in Boston with little or no experience?

The most realistic entry path is through Boston's dense network of biotech and health-tech companies, many of which hire junior ML or data science roles that bridge into senior positions within two to three years. Targeting associate ML engineer or machine learning scientist openings at Cambridge-based research firms, or ML-adjacent roles at Boston fintech companies, builds the production experience senior roles require. Contributing to open-source projects and publishing reproducible work on public repositories strengthens your profile for Boston's research-oriented hiring managers.

Which industries hire the most senior ml engineers in Boston?

Boston senior ml engineer roles concentrate in Technology & Software, Investment & Asset Management, and Automotive, based on current listings on Migrate Mate as of September 2026. Boston's position as a global life sciences hub and its deep cluster of quantitative finance firms make those two sectors especially consistent sources of senior ml engineering demand year-round.

See All 74 Senior ML Engineer Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find Senior ML Engineer Jobs