Senior ML Engineer Jobs in Boston, MA

Senior ML Engineer jobs in Boston are in strong demand, with openings concentrated in the Seaport, Kendall Square, and the Longwood Medical Area across biotech, financial services, and enterprise software. Employers actively hiring include Zoox, Wayfair, and Chewy. Scan the live roles below and apply to whichever ones fit.

Find Senior ML Engineer Jobs

Overview

Open roles108+
Top employerZoox
Work type57% On-site
Top credentialBachelor's
Companies hiring55

Showing 5 of 108+ Senior ML Engineer jobs

Wayfair
Machine Learning Scientist II
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Wayfair
New 23h ago
Machine Learning Scientist II
Wayfair
Boston, Massachusetts
Hybrid
Master's
10,000+

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Motional
Machine Learning Engineer, Data Mining
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Motional
Added 4d ago
Machine Learning Engineer, Data Mining
Motional
Boston, Massachusetts
Data Science & Analytics
Data Engineering
Data Science
$144k - $192k/yr
On-Site
Bachelor's
501-1,000

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State Street
Global Head of AI and ML Field Development, Engineering and Data Science, SVP
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State Street
Added 1w ago
Global Head of AI and ML Field Development, Engineering and Data Science, SVP
State Street
Boston, Massachusetts
$225k - $338k/yr
10,000+

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C
Machine Learning Scientist – Clinical Prediction
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C
Added 1w ago
Machine Learning Scientist – Clinical Prediction
Company
Boston, Massachusetts
Data Science & Analytics
Software Engineering
Data Science
AI (Artificial Intelligence)
ML (Machine Learning)
$148k - $186k/yr
Master's

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E
Senior Machine Learning (ML) Engineer (AI Insurtech)
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E
Added 1w ago
Senior Machine Learning (ML) Engineer (AI Insurtech)
EvolutionIQ
Boston, Massachusetts
Software Engineering
AI (Artificial Intelligence)
ML (Machine Learning)
$190k - $225k/yr

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See All 108+ Senior ML Engineer Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find Senior ML Engineer Jobs

Senior ML Engineer Job Market in Boston

Who's Hiring

  • Zoox
    Zoox12
  • Wayfair
    Wayfair7
  • Chewy
    Chewy4
  • WHOOP
    WHOOP4
  • State Street
    State Street4

Top Industries Hiring

  • Technology & Software31
  • Automotive12
  • Insurance8
  • Science & Research8
  • Investment & Asset Management8

Senior ML Engineer Jobs in Boston: Frequently Asked Questions

How do I get a senior ml engineer job in Boston?

Focus your search on Boston's core hiring clusters: biotech and life sciences firms in the Longwood Medical Area and Cambridge, financial technology companies in the Seaport, and enterprise software companies across the Back Bay and downtown. Candidates who demonstrate production-scale model deployment, strong Python skills, and domain fluency in life sciences or finance move fastest here. Applying directly to mid-size growth companies, not just big tech, widens your options considerably.

Which companies hire senior ml engineers in Boston?

Companies currently hiring senior ml engineers in Boston include Zoox, Wayfair, and Chewy, per current listings on Migrate Mate as of June 2026. Boston's hiring base skews toward research-driven biotech firms, quantitative finance shops, and well-funded software scale-ups rather than a single dominant tech employer.

Are there remote senior ml engineer jobs in Boston?

Yes, though it depends on the role: senior ml engineer positions that emphasize model research and data pipeline work tend to offer more remote flexibility than those requiring on-site lab access or hardware integration. About 43% of senior ml engineer openings tied to Boston are remote or hybrid as of June 2026. Research-focused roles at Boston biotech and software firms are the most likely to support fully remote arrangements.

How can I get a senior ml engineer job in Boston with little or no experience?

The most realistic entry path is through Boston's dense network of biotech and health-tech companies, many of which hire junior ML or data science roles that bridge into senior positions within two to three years. Targeting associate ML engineer or machine learning scientist openings at Cambridge-based research firms, or ML-adjacent roles at Boston fintech companies, builds the production experience senior roles require. Contributing to open-source projects and publishing reproducible work on public repositories strengthens your profile for Boston's research-oriented hiring managers.

Which industries hire the most senior ml engineers in Boston?

Boston senior ml engineer roles concentrate in Technology & Software, Automotive, and Insurance, based on current listings on Migrate Mate as of June 2026. Boston's position as a global life sciences hub and its deep cluster of quantitative finance firms make those two sectors especially consistent sources of senior ml engineering demand year-round.

See All 108+ Senior ML Engineer Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find Senior ML Engineer Jobs