Senior ML Engineer Jobs in Pennsylvania

Senior ML Engineer jobs in Pennsylvania are concentrated in the healthcare IT, financial services, and defense technology sectors, with demand at every level from machine learning engineer through principal and staff engineer. The largest hiring metros are Philadelphia, Pittsburgh, and the Lehigh Valley corridor, where employers like Comcast, Carnegie Mellon University spinouts, and Vanguard maintain significant AI and data science teams. The most in-demand specialties are large language model fine-tuning, MLOps and model deployment infrastructure, and computer vision for healthcare imaging. Find a role that fits below and apply directly.

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Overview

Open roles34
Top employerPenn State University
Top cityPittsburgh, PA
Cities hiring10
Work type63% On-site
Top industryTechnology

Showing 5 of 34+ Senior ML Engineer jobs

Stack AV
Senior Machine Learning Engineer, Static World
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Stack AV
Added 1d ago
Senior Machine Learning Engineer, Static World
Stack AV
Pittsburgh, Pennsylvania
AI (Artificial Intelligence)
Data Engineering
Data Science
Remote (US)

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Penn State University
Artificial Intelligence / Machine Learning Research and Development Engineer
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Penn State University
Added 3d ago
Artificial Intelligence / Machine Learning Research and Development Engineer
Penn State University
University Park, Pennsylvania
Customer Support
Solutions Engineering & Architecture
Technical Product & Program Management
$146k - $319k/yr
On-Site
Master's degree
10,000+

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Vail Resorts
Principal Machine Learning Engineer
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Vail Resorts
Added 5d ago
Principal Machine Learning Engineer
Vail Resorts
Pennsylvania
Software Engineering
Solutions Engineering & Architecture
Specialized Engineering
Technical Program Management
$140k - $185k/yr
On-Site
Bachelor's degree in statistics
10,000+

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LexisNexis Reed Tech
Principal Machine Learning Engineer I** Hybrid in Horsham, PA or Remote EST Preferred
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LexisNexis Reed Tech
Added 1w ago
Principal Machine Learning Engineer I** Hybrid in Horsham, PA or Remote EST Preferred
LexisNexis Reed Tech
Horsham, Pennsylvania
Product Management
Software Engineering
Technical Product & Program Management
$136k - $253k/yr
Hybrid
Bachelor's degree in engineering
1,001-5,000

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LexisNexis Legal & Professional
Principal Machine Learning Engineer I** Hybrid in Horsham, PA or Remote EST Preferred
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LexisNexis Legal & Professional
Added 1w ago
Principal Machine Learning Engineer I** Hybrid in Horsham, PA or Remote EST Preferred
LexisNexis Legal & Professional
Horsham, Pennsylvania
Business Operations
Customer Service
Customer Success
$136k - $253k/yr
Hybrid
Bachelor's degree in engineering
10,000+

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See All 34 Senior ML Engineer Jobs in Pennsylvania

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Senior ML Engineer Jobs by City in Pennsylvania

Where Pennsylvania roles are concentrated, by current openings.

Pittsburgh
16 jobs
University Park
4 jobs
Horsham
3 jobs
Malvern
3 jobs
Philadelphia
2 jobs
Erie
1 job
Ambler
1 job
Bethlehem
1 job
Harrisburg
1 job

Senior ML Engineer Job Market in Pennsylvania

A snapshot from current Pennsylvania openings, updated as new roles post.

Who's Hiring

Penn State University
Penn State University4 open roles
Carnegie Mellon University
Carnegie Mellon University3 open roles
Stack AV
Stack AV2 open roles

Top Industries Hiring

  • Technology & Software
  • Manufacturing
  • Education
  • Science & Research

What Pennsylvania Employers Look For

The qualifications that appear most often in senior ML engineer jobs across Pennsylvania.

  • Bachelor's or master's degree in computer science, statistics, or a directly related field
  • Five or more years of production machine learning experience including model deployment and monitoring
  • Proficiency in Python and frameworks such as PyTorch, TensorFlow, or JAX
  • Demonstrated experience designing and maintaining MLOps pipelines and feature stores
  • Strong background in one Pennsylvania-dominant vertical such as healthcare AI, fintech modeling, or defense analytics
  • Experience collaborating with cross-functional teams including data engineering, product, and research science

Senior ML Engineer Jobs in Pennsylvania: Frequently Asked Questions

How do you become a senior ml engineer in Pennsylvania?

Becoming a senior ml engineer in Pennsylvania does not require a state-issued license, but the realistic path runs through a degree in computer science, data science, or a related field followed by several years of progressively complex modeling work. Pennsylvania employers, particularly in the Philadelphia financial corridor and Pittsburgh's robotics and AI ecosystem, typically promote candidates who have shipped production models, led technical design reviews, and mentored junior engineers. Professional certifications from major cloud platforms strengthen candidacy for roles at large Pennsylvania healthcare systems and defense contractors.

How much do senior ML engineers make in Pennsylvania?

Senior ML engineers in Pennsylvania earn a median of about $107,230 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $59,890 for the lowest 10% to over $167,420 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire senior ml engineers in Pennsylvania?

Employers hiring senior ml engineers in Pennsylvania right now include Penn State University, Carnegie Mellon University, and Stack AV, based on current listings on Migrate Mate as of September 2026. Pennsylvania's concentration of healthcare systems, asset management firms, and defense primes means hiring tends to cluster around applied research and production engineering roles rather than pure academic research positions.

Which Pennsylvania cities have the most senior ml engineer jobs?

Pittsburgh, University Park, and Horsham account for the most senior ml engineer openings in Pennsylvania. Philadelphia draws the largest share because of its dense cluster of health systems, financial services firms, and Comcast's technology headquarters, while Pittsburgh benefits from Carnegie Mellon's AI research pipeline and a growing autonomous systems industry, and smaller markets like the Lehigh Valley see openings tied to logistics technology and regional hospital networks.

Are there remote senior ml engineer jobs in Pennsylvania?

Yes, and more than most fields. About 38% of senior ml engineer openings tied to Pennsylvania are remote or hybrid as of September 2026, reflecting how much of the work centers on code, notebooks, and cloud infrastructure rather than physical presence. The parts of the role most consistently done remotely are model experimentation, feature engineering, and code review, while on-site expectations tend to appear in roles requiring access to sensitive healthcare data or classified defense systems.

How can I get hired as a senior ml engineer in Pennsylvania with little or no experience?

The most realistic entry path is securing a machine learning engineer or data scientist role at a Pennsylvania employer and building toward seniority from within. Large Pittsburgh employers connected to Carnegie Mellon's university partnerships regularly bring on new graduates through research collaborations and internship-to-hire pipelines. In Philadelphia, health system AI teams and asset managers like Vanguard run associate data science programs that accept candidates with strong portfolios even without direct industry experience. Contributing to open-source MLOps tooling and earning a cloud platform certification gives candidates a concrete edge in Pennsylvania screening processes.

Where can I find and apply to senior ml engineer jobs in Pennsylvania?

You can find and apply to senior ml engineer jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings across Philadelphia, Pittsburgh, and the rest of the state. Find roles that fit your background and apply directly to the employer through the listing.

See All 34 Senior ML Engineer Jobs in Pennsylvania

Find roles in Pennsylvania that match your experience and apply in just a few clicks.

Find Senior ML Engineer Jobs