Senior ML Engineer Jobs in Pennsylvania
Senior ML Engineer jobs in Pennsylvania are open across Philadelphia, Pittsburgh, and Malvern and other Pennsylvania metros, with employers like Augean Robotics, ClickHouse, and Duolingo hiring at every experience level. Find a role that fits below and apply directly.
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Company Description
IntegriChain is the data and application backbone for market access departments of Life Sciences manufacturers. We deliver the data, the applications, and the business process infrastructure for patient access and therapy commercialization. More than 250 manufacturers rely on our ICyte Platform to orchestrate their commercial and government payer contracting, patient services, and distribution channels. ICyte is the first and only platform that unites the financial, operational, and commercial data sets required to support therapy access in the era of specialty and precision medicine. With ICyte, Life Sciences innovators can digitalize their market access operations, freeing up resources to focus on more data-driven decision support. With ICyte, Life Sciences innovators are digitalizing labor-intensive processes – freeing up their best talent to identify and resolve coverage and availability hurdles and to manage pricing and forecasting complexity. We are headquartered in Philadelphia, PA (USA), with offices in: Ambler, PA (USA); Pune, India; and Medellín, Colombia.
Location: Philadelphia to NYC - This role offers flexibility for daily work location, but candidates must reside in Pennsylvania, New Jersey, or New York and be within a reasonable travel distance of our Philadelphia office, as regular in-person collaboration is required.
Job Description
- Design, build, and deploy AI/ML solutions using Python.
- Develop and integrate solutions using OpenAI APIs and LLM-based workflows.
- Build AI-driven applications and prototypes using Streamlit.
- Leverage Snowflake for analytics, feature engineering, and inference.
- Develop scalable, production-ready ML pipelines.
- Collaborate with product, data engineering, and business teams.
- Optimize model performance, reliability, and cost.
- Support deployment, monitoring, and iteration of AI/ML applications.
- Contribute to AI architecture and best practices.
Qualifications
- 8+ years of experience with Python.
- Hands-on experience with OpenAI APIs and prompt engineering.
- Strong experience with Snowflake.
- Experience building Streamlit applications.
- Experience with application deployment and CI/CD.
- Solid understanding of ML concepts and data pipelines.
- Experience working in Agile environments.
- Bachelor’s or Master’s degree in Computer Science, Data Science, or related field preferred.
What does IntegriChain have to offer?
- Mission driven: Work with the purpose of helping to improve patients' lives!
- Excellent and affordable medical benefits + non-medical perks including Flexible Paid Time Off and much more!
- Robust Learning & Development opportunities including over 700+ development courses free to all employees
IntegriChain is committed to equal treatment and opportunity in all aspects of recruitment, selection, and employment without regard to race, color, religion, national origin, ethnicity, age, sex, marital status, physical or mental disability, gender identity, sexual orientation, veteran or military status, or any other category protected under the law. IntegriChain is an equal opportunity employer; committed to creating a community of inclusion, and an environment free from discrimination, harassment, and retaliation.
See All 7 Senior ML Engineer Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Senior ML Engineer JobsSenior ML Engineer Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Senior ML Engineer Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring
- Augean Robotics1

- ClickHouse1

- Duolingo1

- IntegriChain1

- Motional Ad1

Top Industries Hiring
- Technology & Software7
- Artificial Intelligence1
What Pennsylvania Employers Look For
The qualifications that appear most often in senior ML engineer jobs across Pennsylvania.
- 5 or more years of hands-on machine learning engineering experience in production environments
- Proficiency in Python and ML frameworks such as PyTorch, TensorFlow, or JAX
- Experience designing and deploying end-to-end ML pipelines at scale
- Familiarity with MLOps tooling including experiment tracking, model registries, and CI/CD for models
- Strong understanding of distributed computing and cloud platforms such as AWS, GCP, or Azure
- Graduate degree in computer science, statistics, or a related quantitative field preferred
Senior ML Engineer Jobs in Pennsylvania: Frequently Asked Questions
How many senior ML engineer jobs are there in Pennsylvania?
There are 7+ senior ML engineer openings in Pennsylvania on Migrate Mate as of June 2026, with the most roles in Philadelphia, Pittsburgh, and Malvern. New positions post regularly as employers across Pennsylvania hire.
How much do senior ML engineers make in Pennsylvania?
Senior ML engineers in Pennsylvania earn a median of about $107,230 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $59,890 for the lowest 10% to over $167,420 for the top 10%. Pay rises with experience, specialty, and employer.
Which Pennsylvania cities have the most senior ML engineer jobs?
Philadelphia, Pittsburgh, and Malvern have the most senior ML engineer openings in Pennsylvania right now, with additional roles spread across smaller metros statewide.
Which companies hire senior ML engineers in Pennsylvania?
Employers hiring senior ML engineers in Pennsylvania include Augean Robotics, ClickHouse, and Duolingo, based on current listings on Migrate Mate as of June 2026.
Are there remote senior ML engineer jobs in Pennsylvania?
Yes. About 29% of senior ML engineer openings tied to Pennsylvania are remote or hybrid as of June 2026. The rest are on-site roles based in Pennsylvania metros.
How do I apply for senior ML engineer jobs in Pennsylvania?
You can apply to senior ML engineer jobs in Pennsylvania directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Pennsylvania location, then apply to each one that fits.
See All 7 Senior ML Engineer Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
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