Software Engineer AI Jobs in San Diego, CA

Software Engineer AI jobs in San Diego are in strong demand, concentrated in Sorrento Valley, UTC, and Downtown, across defense tech, biotech, and enterprise software. Employers hiring right now include Qualcomm, University of San Diego, and BIOVIA. Scan the live roles below and apply to whichever ones fit.

Find Software Engineer AI Jobs

Overview

Open roles28
Top employerQualcomm
Work type50% Remote
Top credentialDoctoral degree in Computer Science
Companies hiring12

Showing 5 of 28+ Software Engineer AI jobs

Software Engineer- AI, Autonomy and Platform Development
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Added 2d ago
Software Engineer- AI, Autonomy and Platform Development
Leidos
San Diego, California
Consulting & Professional Services
Software Engineering
Solutions Engineering & Architecture
Technical Program Management
$108k - $195k/yr
Bachelor's degree
10,000+

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# Software Integration Engineer, AI Accelerators
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Added 2d ago
# Software Integration Engineer, AI Accelerators
Qualcomm
San Diego, California
Cloud Engineering
Cybersecurity
Systems Administration
$100k - $149k/yr
Doctoral degree in Computer Science
10,000+

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Senior Staff Software Engineer, AI-Native Engineering - Flow
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Added 2d ago
Senior Staff Software Engineer, AI-Native Engineering - Flow
ServiceNow
San Diego, California
Cloud Engineering
Data Engineering
Software Engineering
$172k - $301k/yr
Remote (US)
10,000+

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Staff Software Engineer, AI-Native Engineering - Flow
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Added 2d ago
Staff Software Engineer, AI-Native Engineering - Flow
ServiceNow
San Diego, California
Cloud Engineering
Data Engineering
Software Engineering
$150k - $262k/yr
Remote (US)
10,000+

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Senior Software Engineer (AI-Assisted Development)
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Added 3d ago
Senior Software Engineer (AI-Assisted Development)
Nathan Kunes Inc
San Diego, California
Embedded Systems Engineering
Engineering (Non-Software)
Technical Program Management
$110k - $140k/yr
Bachelor's degree

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See All 28 Software Engineer AI Jobs in San Diego

Find roles in San Diego that match your experience and apply in just a few clicks.

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Software Engineer AI Job Market in San Diego

Who's Hiring

Qualcomm9 open roles
University of San Diego6 open roles
BIOVIA2 open roles

Software Engineer AI Jobs in San Diego: Frequently Asked Questions

How do I get a software engineer ai job in San Diego?

The strongest path into San Diego's market is targeting the city's defense contractors, biotech firms, and enterprise software companies clustered in Sorrento Valley and UTC. Hands-on experience with machine learning frameworks and familiarity with production deployment gives candidates a clear edge here. Attending local tech meetups and engaging with the UC San Diego and San Diego State University research communities also opens doors that generic applications miss.

Which companies hire software engineer ais in San Diego?

San Diego software engineer ai roles are posted by Qualcomm, University of San Diego, and BIOVIA and others right now, based on current listings on Migrate Mate as of November 2026. San Diego's employer mix leans heavily toward defense and government contractors, life sciences companies, and venture-backed software startups, many of them headquartered or with major engineering hubs in the Torrey Pines and Sorrento Mesa corridors.

Are there remote software engineer ai jobs in San Diego?

Yes, software engineer ai work is largely desk-based and well-suited to remote arrangements. About 75% of software engineer ai openings tied to San Diego are remote or hybrid as of November 2026, reflecting how broadly distributed these teams have become. Model development, data pipeline work, and research roles tend to be the most remote-friendly, while on-site requirements show up most often at defense contractors with security clearance obligations.

How can I get a software engineer ai job in San Diego with little or no experience?

The most realistic entry path locally is targeting junior or associate AI engineer roles at San Diego's mid-size software companies and biotech firms, which hire more junior talent than the large defense primes. Contributing to open-source projects, completing a portfolio of applied ML work, and connecting with the UC San Diego Jacobs School of Engineering alumni network all help. Some defense contractors also run structured new-grad programs that accept candidates without prior industry experience.

See All 28 Software Engineer AI Jobs in San Diego

Find roles in San Diego that match your experience and apply in just a few clicks.

Find Software Engineer AI Jobs