Director of Commercial Operations Visa Sponsorship Jobs in California
Director of commercial operations visa sponsorship jobs in California are concentrated in tech and enterprise software companies across San Francisco, San Jose, and Los Angeles. Employers like Salesforce, Oracle, and Adobe regularly sponsor senior operations leaders. The state's large B2B technology sector and global headquarters presence make it one of the most active markets for sponsored director-level operations roles.
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INTRODUCTION
Denali Therapeutics Inc. is a biotechnology company pioneering a new class of biotherapeutics designed to cross the blood-brain barrier (BBB) using its proprietary TransportVehicle™ platform. With the first FDA-approved biologic specifically designed to cross the BBB, a clinically validated delivery platform and a growing portfolio of therapeutic candidates across all stages of development, we are advancing toward our goal of delivering effective medicines to transform the lives of people living with neurodegenerative diseases, lysosomal storage disorders and other serious diseases.
We invite you to consider an opportunity with Denali to help achieve our goal of delivering meaningful therapeutics to patients.
ROLE AND RESPONSIBILITIES
This role owns day-to-day execution across the commercial revenue cycle for our first commercial product, including order management, order-to-cash, accounts receivable and credit management, pricing operations, revenue recognition and gross-to-net reserves, and commercial-cycle close and controls. As the commercial footprint expands across products and geographies, this role is expected to build scalable, well-controlled processes rather than simply operate existing ones. This is a self-contributor role which expects to expand in the future as Denali scale and grow across the pipeline of drug candidates.
Key Accountabilities/Core Job Responsibilities:
Order Management, Revenue Recognition and Gross-to-Net (“GTN”)
- Oversee daily order management, including order review and release, credit and compliance holds, pricing conditions, delivery confirmation, and billing execution in SAP.
- Serve as the finance process owner for the end-to-end order-to-cash process, from customer master and contract setup through invoicing and cash application, all the way to closing the books and finalizing accounting reconciliations.
- Manage the operational and financial interface with the third-party logistics provider, specialty distributors, and international distribution partners, including order flow, delivery reporting, fee and chargeback submissions, and monthly reconciliations.
- Lead the preparation, analysis, and review of GTN and the related roll-forward. Prepare revenue and GTN inputs for external reporting, including the product revenue footnote, GTN roll-forward tables, and supporting tie-outs for 10-Q and 10-K filings.
Treasury Operations, Accounts Receivable and Credit Management
- Manage accounts receivable operations, including aging review, collections cadence, cash application, deduction and dispute resolution.
- Develop, implement and maintain the policy around allowance for credit losses.
- Assist with treasury operations, including daily cash positioning, bank account administration and access, and preparation of short-term cash forecasts supporting liquidity management.
Technical Accounting and Contracts Review
- Review commercial agreements for financial terms, revenue recognition implications, and downstream system and process impacts.
- Assist with preparation of technical accounting memos on revenue and commercial arrangements, including ASC 606 analyses, new contract structures, and implementation of new accounting standards.
- Maintain the revenue recognition accounting policy and related position papers and support their review with the Controller organization and external auditors. Serve as process owner for commercial-cycle SOX controls.
BASIC QUALIFICATIONS
- Typically requires a Bachelor's degree in Accounting, Finance, or a related field and 12+ years of progressive accounting and finance experience, including commercial and revenue accounting under ASC 606.
- Demonstrated ownership of order-to-cash operations, including order management, accounts receivable, collections, and customer credit, at a subject-matter-expert level.
- Strong working knowledge of U.S. GAAP, SOX compliance, and public company reporting requirements.
- Demonstrated ability to partner cross-functionally with Commercial, Market Access, Supply Chain, IT, Legal, and Tax, and to communicate financial concepts to non-finance stakeholders.
- Ability to operate effectively in a fast-paced, early commercial environment where processes are still being built.
PREFERRED QUALIFICATIONS
- CPA strongly preferred (active or inactive)
- Big Four public accounting experience
- International commercial experience
- Advanced Excel skills and comfort working with large transactional data sets and reconciliations
- Demonstrated commitment to actively leveraging AI tools and proactively identifying opportunities to integrate AI into processes and workflows
- Familiarity with U.S. government pricing programs, including Medicaid, 340B, and Medicare Part D
- Experience with SAP, FloQast, Workiva
- Experience in a pharmaceutical, biotechnology, or life sciences company
COMPENSATION
- Salary Range: $159,000.00 to $207,000.00. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Denali offers a competitive total rewards package, which includes a 401k, healthcare coverage, ESPP and a broad range of other benefits.
This compensation and benefits information is based on Denali’s good faith estimate as of the date of publication and may be modified in the future.
Denali is committed to its core company value of unity by creating a diverse and inclusive environment. We are proud to be an equal opportunity employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity and/or expression, status as a veteran, basis of disability, or any other federal, state, or local protected class.
Director of Commercial Operations Job Roles in California
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Search Director of Commercial Operations Jobs in CaliforniaDirector of Commercial Operations Jobs in California: Frequently Asked Questions
Which companies in California sponsor visas for director of commercial operations roles?
Large technology and enterprise software companies are among the most active sponsors for director of commercial operations positions in California. Firms like Salesforce, Google, Cisco, Oracle, and Adobe have established immigration programs and regularly file sponsorship petitions for senior operations leaders. Life sciences companies in the San Diego and San Francisco Bay Area also sponsor at the director level, particularly for roles overseeing commercial strategy and go-to-market operations.
What visa types realistically apply to director of commercial operations jobs in California?
Director of commercial operations is a specialty occupation requiring a directly related bachelor's degree, so H-1B visa is the primary visa path. Australian nationals can pursue the E-3 visa, which has no lottery and an annual cap that has never been exhausted. Chilean nationals may qualify under H-1B1 visa and Singaporean nationals under the Singapore H-1B visa1 track. For longer-term stays, EB-2 or EB-3 employment-based green cards through PERM labor certification are common for director-level hires at large California employers.
How to find director of commercial operations visa sponsorship jobs in California?
Migrate Mate lists California employers with verified visa sponsorship history for director of commercial operations roles, searchable by city and company. Because sponsorship at the director level often depends on a company's existing immigration infrastructure, focusing on employers with a track record of H-1B or E-3 filings in operations leadership saves significant time. Migrate Mate surfaces that filing history so you can prioritize outreach to companies already set up to sponsor senior hires.
Which California cities have the most director of commercial operations sponsorship opportunities?
San Francisco and San Jose account for the highest concentration of sponsored director of commercial operations roles, driven by the density of enterprise technology and SaaS companies headquartered there. Los Angeles is a growing market, particularly in media technology, e-commerce, and consumer goods. San Diego sees demand from life sciences and defense technology firms. Smaller hubs like Santa Clara and Redwood City also have active sponsorship activity within Silicon Valley's corporate campuses.
Are there California-specific factors that affect visa sponsorship for director of commercial operations roles?
California's high concentration of multinational technology and life sciences headquarters means many companies already have immigration counsel and established sponsorship processes for senior roles. California Labor Code requirements add compliance steps for employers, but these typically do not impede the federal visa process. The state's large F-1 alumni base from universities like Stanford, UC Berkeley, and UCLA also means many sponsoring employers are experienced with transitions from OPT or STEM OPT into H-1B status at the director level.
What is the prevailing wage for sponsored director of commercial operations jobs in California?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.