Biotech & Pharma F-1 STEM OPT Sponsorship Jobs in Delaware
Delaware's biotech and pharma sector, anchored by companies like AstraZeneca, Incyte, and DuPont's life sciences divisions near Wilmington and the I-95 corridor, actively hires F-1 STEM OPT graduates in research, analytical chemistry, and regulatory roles. The state's proximity to Philadelphia's biotech cluster extends your employer options significantly.
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Get Access To All JobsINTRODUCTION
A global biopharmaceutical company on a mission to Solve On, Incyte follows science to find solutions for patients with unmet medical needs. Through the discovery, development, and commercialization of proprietary therapeutics, Incyte has established a portfolio of first-in-class medicines for patients and a strong pipeline of products in Hematology, Oncology and Inflammation and Autoimmunity.
Headquartered in Wilmington, Delaware, Incyte has operations in North America, Europe, and Asia.
The Biotransformation group within Drug Metabolism and Bioanalysis (DMB) supports discovery and development programs through characterization of drug metabolism and disposition.
We are seeking an experienced scientist who has the flexibility to provide hands-on (lab-based) support of biotransformation (metabolite identification) activities across a portfolio of small molecule programs. The incumbent will contribute to metabolite identification and data interpretation for compounds during optimization and development, while scientifically and strategically interfacing with other DMPK colleagues as well as Medicinal Chemistry partners.
ESSENTIAL FUNCTIONS OF THE JOB
- Conduct in vitro and in vivo biotransformation studies, including hepatocyte, microsomal, and radiolabeled (e.g., 14C) ADME investigations
- Perform metabolite identification using LC-MS/MS and high-resolution mass spectrometry platforms (e.g., Orbitrap, QTOF)
- Analyze and interpret mass spectrometry data to characterize metabolic pathways and identify potential liabilities
- Serve as the biotransformation representative on assigned discovery program(s), with level of independence commensurate with experience
- Generate and communicate metabolite identification results to support medicinal chemistry and program decision-making
- Support development programs through analysis and reporting of preclinical and clinical ADME studies, including mass balance and human ADME studies
- Prepare and review technical reports and contribute to regulatory documents (IND/NDA) as appropriate
- Collaborate with cross-functional teams and coordinate external CRO activities as needed
MINIMUM QUALIFICATIONS
- Ph.D. in Pharmaceutical Sciences, Chemistry, Biochemistry, or a related discipline with 0–5+ years of relevant industry or postdoctoral experience
or
- M.S. with 4–8+ years of relevant industry experience
or
- B.S. with 6–10+ years of relevant industry experience
- Experience in biotransformation and metabolite identification in a pharmaceutical or CRO environment
- Hands-on experience with in vitro metabolism systems (e.g., hepatocytes, microsomes)
- Experience interpreting LC-MS/MS or high-resolution MS data for metabolite identification
- Experience working with or supporting radiolabeled (e.g., 14C) ADME studies, including sample handling, data generation, or interpretation
- Strong understanding of drug metabolism pathways (e.g., CYP, UGT)
- Ability to analyze complex data and clearly communicate findings to matrix team members
PREFERRED QUALIFICATIONS
-
- Experience contributing to regulatory submissions (IND/NDA)
- Familiarity with metabolite identification software (e.g., UNIFI, Compound Discoverer, MassMetaSite)
- Experience working in a cross-functional drug discovery environment
Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
We Respect Your Privacy
The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.
During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here.
You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work.
Please contact privacy@incyte.com if you have any questions or concerns or would like to exercise your rights.
INTRODUCTION
A global biopharmaceutical company on a mission to Solve On, Incyte follows science to find solutions for patients with unmet medical needs. Through the discovery, development, and commercialization of proprietary therapeutics, Incyte has established a portfolio of first-in-class medicines for patients and a strong pipeline of products in Hematology, Oncology and Inflammation and Autoimmunity.
Headquartered in Wilmington, Delaware, Incyte has operations in North America, Europe, and Asia.
The Biotransformation group within Drug Metabolism and Bioanalysis (DMB) supports discovery and development programs through characterization of drug metabolism and disposition.
We are seeking an experienced scientist who has the flexibility to provide hands-on (lab-based) support of biotransformation (metabolite identification) activities across a portfolio of small molecule programs. The incumbent will contribute to metabolite identification and data interpretation for compounds during optimization and development, while scientifically and strategically interfacing with other DMPK colleagues as well as Medicinal Chemistry partners.
ESSENTIAL FUNCTIONS OF THE JOB
- Conduct in vitro and in vivo biotransformation studies, including hepatocyte, microsomal, and radiolabeled (e.g., 14C) ADME investigations
- Perform metabolite identification using LC-MS/MS and high-resolution mass spectrometry platforms (e.g., Orbitrap, QTOF)
- Analyze and interpret mass spectrometry data to characterize metabolic pathways and identify potential liabilities
- Serve as the biotransformation representative on assigned discovery program(s), with level of independence commensurate with experience
- Generate and communicate metabolite identification results to support medicinal chemistry and program decision-making
- Support development programs through analysis and reporting of preclinical and clinical ADME studies, including mass balance and human ADME studies
- Prepare and review technical reports and contribute to regulatory documents (IND/NDA) as appropriate
- Collaborate with cross-functional teams and coordinate external CRO activities as needed
MINIMUM QUALIFICATIONS
- Ph.D. in Pharmaceutical Sciences, Chemistry, Biochemistry, or a related discipline with 0–5+ years of relevant industry or postdoctoral experience
or
- M.S. with 4–8+ years of relevant industry experience
or
- B.S. with 6–10+ years of relevant industry experience
- Experience in biotransformation and metabolite identification in a pharmaceutical or CRO environment
- Hands-on experience with in vitro metabolism systems (e.g., hepatocytes, microsomes)
- Experience interpreting LC-MS/MS or high-resolution MS data for metabolite identification
- Experience working with or supporting radiolabeled (e.g., 14C) ADME studies, including sample handling, data generation, or interpretation
- Strong understanding of drug metabolism pathways (e.g., CYP, UGT)
- Ability to analyze complex data and clearly communicate findings to matrix team members
PREFERRED QUALIFICATIONS
-
- Experience contributing to regulatory submissions (IND/NDA)
- Familiarity with metabolite identification software (e.g., UNIFI, Compound Discoverer, MassMetaSite)
- Experience working in a cross-functional drug discovery environment
Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.
Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.
We Respect Your Privacy
The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.
During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here.
You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work.
Please contact privacy@incyte.com if you have any questions or concerns or would like to exercise your rights.
Biotech & Pharma Job Roles in Delaware
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Search Biotech & Pharma Jobs in DelawareBiotech & Pharma Jobs in Delaware: Frequently Asked Questions
Which biotech and pharma companies sponsor F-1 STEM OPT visas in Delaware?
AstraZeneca, Incyte Corporation, and W.L. Gore and Associates are among the Delaware-based employers with documented histories of hiring F-1 STEM OPT workers in life sciences roles. Contract research organizations and smaller biotech firms clustered along the Wilmington corridor also participate in STEM OPT sponsorship, though individual hiring decisions vary by department, budget cycle, and the specific role's STEM CIP code eligibility.
Which cities in Delaware have the most biotech and pharma F-1 STEM OPT sponsorship jobs?
Wilmington and its northern Delaware suburbs account for the largest concentration of biotech and pharma employers in the state, with the Route 202 and I-95 corridors hosting major research and commercial operations. Newark, home to the University of Delaware's science and engineering programs, also attracts life sciences employers seeking STEM OPT candidates. Dover has a smaller but growing presence in pharmaceutical manufacturing.
What types of biotech and pharma roles typically qualify for F-1 STEM OPT sponsorship in Delaware?
Roles most commonly qualifying include analytical chemist, research associate, bioprocess engineer, computational biologist, regulatory affairs associate, and quality assurance specialist. Eligibility depends on whether the position's duties align with a STEM-designated CIP code matching your degree field, as determined by your Designated School Official. Positions in data science applied to drug discovery or clinical trials also frequently qualify. O*NET occupation profiles can help verify alignment.
How do I find biotech and pharma F-1 STEM OPT sponsorship jobs in Delaware?
Migrate Mate lets you filter specifically for biotech and pharma employers in Delaware that have filed for STEM OPT and H-1B visa sponsorship, so you can focus on companies with a verified sponsorship track record rather than guessing. Delaware's market is concentrated enough that a targeted search by county and employer type yields a practical shortlist quickly. Pair your search with outreach to employers' university recruiting contacts at University of Delaware and Delaware State University.
Are there any state-specific considerations for F-1 STEM OPT sponsorship in Delaware's biotech and pharma sector?
Delaware's small geographic size means many employers operate across the Delaware-Pennsylvania-New Jersey tri-state area, so an employer headquartered in Wilmington may assign you to a facility in New Jersey without affecting your STEM OPT authorization, as long as your employment authorization documentation reflects the actual work location. Delaware also has a relatively strong biosciences policy environment through the Delaware Bioscience Association, which connects employers with workforce programs relevant to international hiring.