Scientist Visa Sponsorship Jobs in Ohio
Scientist visa sponsorship jobs in Ohio are concentrated in research-intensive sectors, with major employers including Battelle Memorial Institute, Ohio State University, and Procter & Gamble operating across Columbus, Cincinnati, and Cleveland. Ohio's deep university network and national laboratory presence make it a consistent source of sponsored research and applied science positions.
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Get Access To All JobsForge Your Future with Us:
At Forge Biologics, we believe in turning bold ideas into life-changing realities. Our mission is simple yet powerful: to enable access to life-changing gene therapies and help bring them from ideas into reality. We partner with scientists, physicians, biotech and pharma innovators, and patient communities — all united by one goal: improving lives. If you're driven by purpose and excited to make a tangible impact, this is where your journey begins.
Our team works out of The Hearth, a state-of-the-art, 200,000-square-foot cGMP facility in Columbus, Ohio. Here, you won't just watch innovation happen — you'll be part of it. Whether you're scaling AAV manufacturing, collaborating on cutting-edge therapies, or supporting complex technical projects, you'll play a key role in bringing hope to patients with genetic diseases.
What sets Forge apart is our culture of H.O.P.E. We are hardworking, showing up each day with determination and grit. We are open, creating a space where ideas flow freely, and every voice is valued. We are purpose-driven, with every task directly tied to changing lives. And we are engaged, energized by the challenges we face and the milestones we achieve together.
At Forge, your growth matters. We're committed to helping you expand your skills, take on new challenges, and develop your career through mentorship, hands-on learning, and opportunities for advancement. Our people are our greatest investment, and we're proud to see team members grow with us.
If you're ready to use your talent to help deliver hope to patients around the world, join us — and be part of something bigger than yourself.
About the Role:
The Scientist I, Quality Control (Analytical) role will primarily focus on analytical method execution, method qualification, method validation, and troubleshooting efforts. This position will be responsible for executing in-process, final product, and stability testing for AAV vectors, plasmids, and microbial and mammalian cell banks, while ensuring that activities occur in an efficient and cGMP compliant manner. This role will function as a subject matter expert (SME) for either nucleic acid-based methods (e.g. ddPCR, qPCR), protein-based assays (e.g. CE, AUC), or cell-based assays (e.g. TCID50, potency). This position will also be responsible for fostering innovation within the QC department, either independently or by partnering with Analytical Development, ensuring cutting edge technologies are employed to maintain the highest QC standards in the analysis of gene therapy products. This role provides an opportunity to play a significant impact in the success of client gene therapy programs.
Responsibilities:
- Perform in-process, release, and stability testing for assays relevant to viral vector/gene therapy products, plasmids, and cell banks, including in-process testing, lot release testing, assay qualification, and validations.
- Function as an SME for either nucleic acid-based methods (e.g. ddPCR, qPCR), protein-based assays (e.g. CE, AUC), or cell-based assays (e.g. TCID50, potency). Additionally, perform advanced analytical testing quality control assays, including compendial testing, ELISA, and viability assays, to assess the quality, potency, and safety of AAV vector products.
- Support troubleshooting of processes/assays as an SME. Represent QC as a SME during audits and inspections.
- Ensure effective qualifications, validations, and transfer of analytical methods to Quality Control in a phase-appropriate fashion, to support pre-clinical, clinical, and commercial activities.
- Contribute to authoring and/or reviewing QC documentation, including but not limited to: SOPs, analytical methods and forms, qualifications protocols, and validation protocols.
- Conduct thorough investigations to determine root cause of OOS investigations and other non-conforming results and implements appropriate corrective and preventative actions in a timely manner.
- Provide support for Deviations, Change Controls, and CAPAs related to in process and final product testing.
- Review and approve GMP documentation associated with in process, final product, and stability testing.
- Drive the development, optimization, and validation of novel analytical methods to enhance quality control processes.
- Provide technical guidance and mentorship to junior team members, promoting their personal growth and skill development.
- Compile data with minimal oversight, generating reports, and archiving assay data; responsible for performing the analysis and interpretation of assay results.
- Support regulatory and client inspections and internal audits of GMP systems.
- Manage tracking and trending of in process and final product testing data, including, but not limited to; leading/participating in out of specification (OOS)/out of trend (OOT) Laboratory Investigations.
Qualifications
- Bachelor's, Master's, or PhD in a relevant scientific field (e.g., biology, biochemistry, molecular biology). Advanced degree preferred.
- SME for either nucleic acid-based methods (e.g. ddPCR, qPCR), protein-based assays (e.g. CE, AUC), or cell-based assays (e.g. TCID50, potency) based on experience. Advanced knowledge of complex molecular biology, biochemistry, or cell biology techniques and analytical methods (e.g., qPCR, cell-based infectivity assays, potency assays).
- Proven ability to execute, troubleshoot, and optimize analytical assays.
- Strong analytical and data interpretation skills to assess and drive quality improvement through the analysis of quality metrics and performance data.
- Robust understanding of cGMP requirements as they pertain to Quality Control and Analytical Development testing.
- Experience in leading, mentoring, and guiding junior team members.
- Experience with electronic Quality Management Systems (EQMS), Laboratory Information Management Systems (LIMS), etc.
Work Environment and Physical Demands
This position works in both a laboratory environment and typical office environment where the physical work demands will vary depending on the specific tasks and duties required of the job. The employee will be stationary (standing/sitting) for extended periods of time. Employees regularly wear personal protective equipment based on the task being performed. Must be able to work in a confined space, such as a clean room or laboratory environment. Ability to identify small details within the field of vision, distinguish between different colors, and accurately identify objects within a specific area.
Forge Biologics is an equal opportunity employer dedicated to building an inclusive and diverse workforce. Forge Biologics provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
We've Got You Covered:
At Forge Biologics, we believe our people deserve to be taken care of – in and out of the workplace. We've built a comprehensive compensation and benefits package designed to help you thrive, grow, and feel valued every step of the way:
Health from day one
- Health, dental and vision insurance start your first day – with 90% of premiums covered for you and your family.
Time to recharge
- A competitive paid time off plan – because rest fuels innovation.
- 12 weeks of fully paid parental leave so you can focus on family when it matters most.
Rewarding your impact
- Annual bonus opportunities for all full-time team members.
- 401(k) with company match to help you plan for the future.
- Special employee discounts, including childcare and dependent care savings.
Your wellness, supported
- Onsite fitness facility at The Hearth.
- Mental health counseling and financial planning services through our Employee Assistance Program.
- Employer-paid short and long-term disability coverage to protect your peace of mind.
Fuel for your workday
- A fully stocked kitchen with free snacks and beverages – we keep you energized and ready for what's next.
Grow with us
- Ongoing professional development resources, training, and mentorship programs to help you build your care and grow within Forge.
Forge Your Future with Us:
At Forge Biologics, we believe in turning bold ideas into life-changing realities. Our mission is simple yet powerful: to enable access to life-changing gene therapies and help bring them from ideas into reality. We partner with scientists, physicians, biotech and pharma innovators, and patient communities — all united by one goal: improving lives. If you're driven by purpose and excited to make a tangible impact, this is where your journey begins.
Our team works out of The Hearth, a state-of-the-art, 200,000-square-foot cGMP facility in Columbus, Ohio. Here, you won't just watch innovation happen — you'll be part of it. Whether you're scaling AAV manufacturing, collaborating on cutting-edge therapies, or supporting complex technical projects, you'll play a key role in bringing hope to patients with genetic diseases.
What sets Forge apart is our culture of H.O.P.E. We are hardworking, showing up each day with determination and grit. We are open, creating a space where ideas flow freely, and every voice is valued. We are purpose-driven, with every task directly tied to changing lives. And we are engaged, energized by the challenges we face and the milestones we achieve together.
At Forge, your growth matters. We're committed to helping you expand your skills, take on new challenges, and develop your career through mentorship, hands-on learning, and opportunities for advancement. Our people are our greatest investment, and we're proud to see team members grow with us.
If you're ready to use your talent to help deliver hope to patients around the world, join us — and be part of something bigger than yourself.
About the Role:
The Scientist I, Quality Control (Analytical) role will primarily focus on analytical method execution, method qualification, method validation, and troubleshooting efforts. This position will be responsible for executing in-process, final product, and stability testing for AAV vectors, plasmids, and microbial and mammalian cell banks, while ensuring that activities occur in an efficient and cGMP compliant manner. This role will function as a subject matter expert (SME) for either nucleic acid-based methods (e.g. ddPCR, qPCR), protein-based assays (e.g. CE, AUC), or cell-based assays (e.g. TCID50, potency). This position will also be responsible for fostering innovation within the QC department, either independently or by partnering with Analytical Development, ensuring cutting edge technologies are employed to maintain the highest QC standards in the analysis of gene therapy products. This role provides an opportunity to play a significant impact in the success of client gene therapy programs.
Responsibilities:
- Perform in-process, release, and stability testing for assays relevant to viral vector/gene therapy products, plasmids, and cell banks, including in-process testing, lot release testing, assay qualification, and validations.
- Function as an SME for either nucleic acid-based methods (e.g. ddPCR, qPCR), protein-based assays (e.g. CE, AUC), or cell-based assays (e.g. TCID50, potency). Additionally, perform advanced analytical testing quality control assays, including compendial testing, ELISA, and viability assays, to assess the quality, potency, and safety of AAV vector products.
- Support troubleshooting of processes/assays as an SME. Represent QC as a SME during audits and inspections.
- Ensure effective qualifications, validations, and transfer of analytical methods to Quality Control in a phase-appropriate fashion, to support pre-clinical, clinical, and commercial activities.
- Contribute to authoring and/or reviewing QC documentation, including but not limited to: SOPs, analytical methods and forms, qualifications protocols, and validation protocols.
- Conduct thorough investigations to determine root cause of OOS investigations and other non-conforming results and implements appropriate corrective and preventative actions in a timely manner.
- Provide support for Deviations, Change Controls, and CAPAs related to in process and final product testing.
- Review and approve GMP documentation associated with in process, final product, and stability testing.
- Drive the development, optimization, and validation of novel analytical methods to enhance quality control processes.
- Provide technical guidance and mentorship to junior team members, promoting their personal growth and skill development.
- Compile data with minimal oversight, generating reports, and archiving assay data; responsible for performing the analysis and interpretation of assay results.
- Support regulatory and client inspections and internal audits of GMP systems.
- Manage tracking and trending of in process and final product testing data, including, but not limited to; leading/participating in out of specification (OOS)/out of trend (OOT) Laboratory Investigations.
Qualifications
- Bachelor's, Master's, or PhD in a relevant scientific field (e.g., biology, biochemistry, molecular biology). Advanced degree preferred.
- SME for either nucleic acid-based methods (e.g. ddPCR, qPCR), protein-based assays (e.g. CE, AUC), or cell-based assays (e.g. TCID50, potency) based on experience. Advanced knowledge of complex molecular biology, biochemistry, or cell biology techniques and analytical methods (e.g., qPCR, cell-based infectivity assays, potency assays).
- Proven ability to execute, troubleshoot, and optimize analytical assays.
- Strong analytical and data interpretation skills to assess and drive quality improvement through the analysis of quality metrics and performance data.
- Robust understanding of cGMP requirements as they pertain to Quality Control and Analytical Development testing.
- Experience in leading, mentoring, and guiding junior team members.
- Experience with electronic Quality Management Systems (EQMS), Laboratory Information Management Systems (LIMS), etc.
Work Environment and Physical Demands
This position works in both a laboratory environment and typical office environment where the physical work demands will vary depending on the specific tasks and duties required of the job. The employee will be stationary (standing/sitting) for extended periods of time. Employees regularly wear personal protective equipment based on the task being performed. Must be able to work in a confined space, such as a clean room or laboratory environment. Ability to identify small details within the field of vision, distinguish between different colors, and accurately identify objects within a specific area.
Forge Biologics is an equal opportunity employer dedicated to building an inclusive and diverse workforce. Forge Biologics provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
We've Got You Covered:
At Forge Biologics, we believe our people deserve to be taken care of – in and out of the workplace. We've built a comprehensive compensation and benefits package designed to help you thrive, grow, and feel valued every step of the way:
Health from day one
- Health, dental and vision insurance start your first day – with 90% of premiums covered for you and your family.
Time to recharge
- A competitive paid time off plan – because rest fuels innovation.
- 12 weeks of fully paid parental leave so you can focus on family when it matters most.
Rewarding your impact
- Annual bonus opportunities for all full-time team members.
- 401(k) with company match to help you plan for the future.
- Special employee discounts, including childcare and dependent care savings.
Your wellness, supported
- Onsite fitness facility at The Hearth.
- Mental health counseling and financial planning services through our Employee Assistance Program.
- Employer-paid short and long-term disability coverage to protect your peace of mind.
Fuel for your workday
- A fully stocked kitchen with free snacks and beverages – we keep you energized and ready for what's next.
Grow with us
- Ongoing professional development resources, training, and mentorship programs to help you build your care and grow within Forge.
Scientist Job Roles in Ohio
See all 141+ Scientist Jobs in Ohio
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Search Scientist Jobs in OhioScientist Jobs in Ohio: Frequently Asked Questions
Which companies sponsor visas for scientists in Ohio?
Battelle Memorial Institute in Columbus is one of Ohio's most active sponsors for research scientists, given its role as the world's largest nonprofit R&D organization. Other consistent sponsors include Procter & Gamble in Cincinnati, Goodyear Tire and Rubber in Akron, and academic medical centers like Cleveland Clinic and Ohio State University Wexner Medical Center, particularly for postdoctoral and staff scientist roles.
Which visa types are most common for scientist roles in Ohio?
The H-1B visa is the most common visa for scientist positions in Ohio, as most research and applied science roles qualify as specialty occupations requiring at least a bachelor's degree in a directly related field. O-1A visas appear for scientists with demonstrated extraordinary ability, such as published researchers or award recipients. J-1 visas are also common for postdoctoral researchers at Ohio's universities, though J-1 holders may face a two-year home residency requirement before transitioning to H-1B status.
How to find scientist visa sponsorship jobs in Ohio?
Migrate Mate filters job listings specifically by visa sponsorship availability, making it straightforward to search for scientist roles in Ohio without sifting through positions that don't support international candidates. You can narrow results by city, research field, or employer type. Given Ohio's concentration of R&D employers and universities, sponsored scientist openings appear regularly on Migrate Mate across Columbus, Cleveland, and Cincinnati.
Which cities in Ohio have the most scientist sponsorship jobs?
Columbus leads due to the presence of Ohio State University, Battelle, and a growing biotech corridor. Cleveland follows closely, anchored by Case Western Reserve University, Cleveland Clinic, and University Hospitals, all of which hire sponsored research scientists regularly. Cincinnati is a strong third, driven by Procter & Gamble's R&D operations and the University of Cincinnati. Akron sees sponsorship activity in polymer science and materials research tied to its industrial base.
Are there state-specific considerations for scientists seeking visa sponsorship in Ohio?
Ohio's university system, including Ohio State, Case Western Reserve, and the University of Cincinnati, creates a pipeline of postdoctoral positions that frequently lead to sponsored staff scientist or research faculty roles. Employers must file a Labor Condition Application with the Department of Labor certifying the offered wage meets prevailing wage levels for the relevant science occupation and Ohio location. Prevailing wages vary by county and job zone, so positions in Columbus or Cleveland may have different wage thresholds than those in smaller Ohio cities.
What is the prevailing wage for sponsored scientist jobs in Ohio?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.